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Architecture to Implement Secure Cloud Computing with Elliptic Curve Cryptography
Debajyoti Mukhopadhyay,Abhay kawade,Akash Thakur,Nikhilesh Chaudhari,Sani Nanekar 한국산학기술학회 2015 SmartCR Vol.5 No.3
Cloud computing is an emerging domain that enables the deployment of a new IT service paradigm. Cloud providers offer a wide range of services which are charged per unit basis. The major challenge facing clouds is security. It includes ensuring the safety of the infrastructure as well as protection against unauthorized access. In this paper, we deal with cloud security services, including key agreements and authentication. By employing Elliptic Curve Cryptography for client authentication process and data storage, we design the Multi-Server Cloud Computing system. Our scheme chooses not to store encryption keys anywhere in the cloud because of the secret isolation guideline. A request counter is used at the time of the client authentication process to prevent replay attacks. To aid in controlled access, a mandatory access control model is preferred. We split the encrypted data and store it on different clouds, which provides security against attacks on the storage server. Restrictions are imposed to ensure only selected employees (administrators) have authority to handle the encrypted data. Our Multi-Server Cloud Computing system is used to fit an environment in which each cloud contains multiple servers that collaborate in serving applications. One cloud is used for client authentication and key agreement, and another cloud for data splitting and combining. Due to strong security and operation efficiency, the proposed secure cloud computing should be most suitable for use in a cloud computing environment.
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Yuji Hotta,Naoya Ieda,Ayako Fukamoto,Tomoya Kataoka,Yoshihiro Kawade,Yasuhiro Maeda,Hidehiko Nakagawa,Kazunori Kimura 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.3
Purpose: To investigate whether relaxation of the rat penile corpus cavernosum could be controlled with NOBL-1, a novel, light-controllable nitric oxide (NO) releaser. Materials and Methods: Fifteen-week-old male Wistar-ST rats were used. The penile corpus cavernosum was prepared and used in an isometric tension study. After noradrenaline (10-5 M) achieved precontraction, the penile corpus cavernosum was irradiated by light (470–500 nm) with and without NOBL-1 (10-6 M). In addition, we noted rats' responses to light with vardenafil (10-6 M), a phosphodiesterase-5 (PDE-5) inhibitor. Next, responses to light in the presence of a guanylate cyclase inhibitor, ODQ (1H-[1,2,4] oxadiazolo[4,3-a]quinoxalin-1-one) (10-5 M), were measured. All measurements were performed in pretreated L-NAME (10-4 M) conditions to inhibit endogenous NO production. Results: Corpus cavernosal smooth muscle, precontracted with noradrenaline, was unchanged by light irradiation in the absence of NOBL-1. However, in the presence of NOBL-1, corpus cavernosal smooth muscle, precontracted with noradrenaline, relaxed in response to light irradiation. After blue light irradiation ceased, tension returned. In addition, the light response was obviously enhanced in the presence of a PDE-5 inhibitor. Conclusions: This study showed that rat corpus cavernosal smooth muscle relaxation can be light-controlled using NOBL-1, a novel, light sensitive NO releaser. Though further in vivo studies are needed to investigate possible usefulness, NOBL-1 may be prove to be a useful tool for erectile dysfunction therapy, specifically in the field of penile rehabilitation.
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