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      • 방광기능에 있어 칼슘통로차단제의 영향

        김갑병 대구효성가톨릭 대학교 1997 연구논문집 Vol.54 No.2

        Purpose:These studies were designed to determine the effect of inhibition of calcium translocation through L-type channels and inhibition of the release of intracellular bound calcium from the sarcoplasmic reticulum(SR) on the ability of the bladder to generate pressure and empty. Methods:Using our isolated rabbit whole bladder preparation, we investigated the effect of selectively inhibiting either the translocation of extracellular calcium using Diltiazem[D](10μM) or intracellular calcium induced calcum release using a combination of Thapsigargin(40μM)+Ryanodine(80μM)[T & R] on the responses to either maximal field stimulation(32Hz, 80V, lms) or maximal bethanechol stimulation(250μM). Two experiments were performed:in the first, the bladder contracted isometrically with 15ml, saline and in the second, the bladder contracted and emptied the 15ml. saline into a bottle hanging from a force transducer, allowing simultaneous measurement of pressure and volume emptied. Flow rate, rate of pressure generation, and work performed were calculated from pressure and volume emptied. Results:Diltiazem produced significant inhibitions of the maximal isometric response to FS. The time to maximal rpessure generation was significantly reduced, whereas the mean rate of pressure generation was increased. R & T inhibited maximum pressure generation to the same degree as Diltiazem. However, there was no effect on the time to maximal pressure generation but the mean rate of pressure generation was significantly reduced. D reduced the percentage volume emptied in response to FS to a significantly greater extent than the response to bethanechol whereas R & T reduced the response to FS and the bethanechol equally. Both drug treatments resulted in significant reduction in the total amount of work performed by the bladder in response to both FS and bethanechol. Conclusions:Bladder function is dependent upon both translocation of extracellular calcium through L-type calcium channels and the stimulated release of calcium from SR(both IP3-sensitive and insensitive sites). Inhibition of either site results in signigicant reductions of the ability of the bladder to generate and sustain pressure, generate power, and perform work. These results are consistent with the hypothesis that several forms of expeimental bladder dysfunction may be directly related to significant alterations in calcium homeostasis that results in the observed dysfunction in the ability of the bladder to generate pressure and empty.

      • KCI등재

        이륙 직후 동력 상실시 활주로로 선회 착륙을 위한 안전 고도에 관한 연구

        송병흠,김갑수 한국항공운항학회 1996 한국항공운항학회지 Vol.4 No.1

        본 연구에서는 항공기 사고의 70% 이상을 차지하는 이ㆍ착륙단계 중에서, 이륙 직후 저고도에서 동력이 상실되었을 경우에 이륙활주로 방향으로 Turning Back하는 것은 어떠한 안전 한계를 지니고 있는지를 알아보기 위하여, 우선 조종사에 대한 설문 조사를 실시하여 비행 경력별로 이륙 직후 동력 상실시의 비상 처치 경향과 위험에 처할 확률을 조사하였다. 그리고 실제 활공 성능이 우수한 M20J 항공기와 기동 성능이 우수한 FH20 항공기를 이용한 비행 시험을 통하여 이륙 직후 Turning Back to Runway조작 시의 고도 손실과 선희시 하강율을 실험 자료로 구하였다. 비행 시험 자료를 비교 적용함은 물론 선희 소요 시간과 고도 손실, 선희율과 활공 속도와의 관계 등의 항공 역학적 이론을 적용한 분석 근거에 기초하여 안전하게 Turning Back to Runway 조작을 시작할 수 있는 안전 고도 한계 및 선희율을 제시하였다.

      • 반연속폭포 HMM을 이용한 한국어 지역명 인식

        조병서,최갑석,이용동 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

        This paper studies on the Korean word recognition using the semi-continuous hidden Markov model(SCHMM) which approximate the discrete hidden Markov model(DHMM) to the continuous hidden Markov models(CHMM). In generating of this model, the output probability of an input vector, which is assumed to the mixture continuous Gaussian distribution, is linearly combined with the probability function of each input vector and the symbol output of codewords for approximating to the CHMM, In the word recognition, this model recognized words more correctly than the DHMM because of reducing a quantized distortion due to the DHMM. In order to evaluate this model, comparing experiments between DHMM and SCHMM are carried out for DDD area names. Also, input vector takes the traditional LPC or the LPC cepstrum using euclidean distance. As a result, recognition rate of the SCHMM using the LPC cepstrum is improved.

      • 膀胱의 吸收能에 關한 實驗的硏究

        閔丙甲 中央醫學社 1965 中央醫學 Vol.8 No.3

        A study was made on absorption of Radioactive iodine (I^(131)) in the urinary bladder of the rabbit. Activity of blood sample drawn at certain intervals from 15 minutes up to 6 hours following introduction of NaI^(131) into the bladder was measured with well counter. 1) Following administration of 2 ml. of solution containing 20μC of I^(131), average count . per minute of 1 ml of blood sample was 343 at 15 minutes, 688 at one hour, 1116 at 3 hours and 1449 at 6 hours, respetively. There was steady increase in CPM with passage of time, indicating the defnite evidence of absorption of I^(131) in the urinary bladder. 2) Effect of different solution on the absorption of I131 was studied using both distilled water and saline solution with different concentration. With distilled water, activity was always higher than one with either physiolocal or 3% saline solution, irrespective of intervals at which it was measured. Activity with distilled water is 2 times and 3 times that with either physiological or 3% saline solution at 3 and 6 hours, respectively. 3) No significant difference in activity between 3% saline and physiological saline solution was found.

      • Hilbert 空間 ℓ_2에서 無限行列로 表示되는 線型作用素 (Ⅱ)

        尹甲炳 慶熙大學校 1989 論文集 Vol.18 No.-

        Hillert 空間 ℓ_2에서 標準基底에 관하여 無限行列 A=(a_(ij))로 表示되는 線型作用素(이것도 같은 文字 A로 나타내기로 함)의 連續性에 관하여 考察하였음. 主要한 結果는 §4의 定理 1) A는 임의 (無限)行列, U는 임의 unitary行列, B=UAU^*라함. 다음 條件들은 서로 同値하다. (ⅰ) A는 連續 (ⅱ) 모든 U, i, j에 대하여 || B_i ||, || B^j ||≤M 인 陽의 常數 M가 存在(B_i, B^j는 行列 B의 제i行 및 제j列로 된 Voctor) (ⅲ) 임의 U에 대하여 한 陽의 常數 M이 存在해서, 모든 i, j에 대하여 || B_i ||, || B^j ||≤M (ⅳ) 모든 U, i, j에 대하여 || B_i ||, || B^j ||<∞

      • KCI등재

        조선조 교육·문화 정책과정에 있어서 정파간의 이익갈등 분석 : 16세기 붕당간의 관계를 중심으로 Mainly on the Relationship between Factional Parties during 16th Century

        이병갑 서울대학교 행정대학원 2004 行政論叢 Vol.42 No.1

        교육·문화정책과정에 있어서 정파간의 이익갈등현상을 16세기의 경서번역정책과 문묘종향정책을 중심으로 논의하였다. 경서번역정책의 경우, 각 정파는 성균관·사학·향교 서당의 교재로 사용되고 있는 경서를 언해하는 데 주도권을 장악하기 위하여 이익갈등을 벌였다. 집권세력인 동인의 의도대로 동인이 존봉하는 인물인 이황 사서석의(四書釋義)가 교정청의 언해과정에 반영되었다. 이는 동인의 영향력 증대 즉, 정치적 이익과 관련되고 있다. 동인과 서인간에 이익갈등은 경쟁의 형태로 전개되었으며, 갈등의 귀결은 동인의 권력유지였다. 문화정책의 경우 유현(儒賢)의 문묘종향정책에 관한 것이었으며, 이 문제는 남인과 서인·북인간에 전개되었고, 이익갈등의 전개양상은 대립이었으며, 상당한 기간이 경과한 후 오현의 문묘종향을 반대한 북인 핵심세력이 권력원에서 축출되는 것으로 귀결되었다. This article is the analysis of the conflict of interest between parties in educational and cultural policy process during 16th century. In the process of educational policy, factional parties wanted to have the initiative concerning the policy for translation in the confucious books. The ruling party was Easterners[Dongin(東人)], they respected Yi Hwang(李滉) who wrote Kyungseoseokyi(經書釋義). His books were reflected on the process of translation in the correction authority(校正廳). It signifies the increase of influence of Easterners, for example, political interest. The conflict of interest between Dongin and Westerners[Seoin(西人)]was progressed through their competition. As a result of the conflict, the party of Easterners[Dongin(東人)]reinforced their political power. In the process of cultural policy, factional parties wanted to be selected in the Confucian Schrines(文廟), whom they worshiped. The conflict of another interest arose among Southerners[Namin(南人)], Northerners[Pukin(北人)]and Westerners. The type of conflicts was each other's antagonism and its consequence was Pukin's leader's expulsion out of the official position after several years. The interest of Namin was reflected in the process of placing the Confusion Schrine.

      • KCI등재후보

        단일전극을 가진 마이크로 가스센서의 제작 및 특성

        송갑득,박영일,이상문,이윤수,최낙진,주병수,서무교,허증수,이덕동 한국센서학회 2002 센서학회지 Vol.11 No.6

        센서의 안정도와 감도를 개선시킬 수 있는 단일전극을 가진 열선형 마이크로 가스센서를 제작하였다. 일반적으로, 금속산화물 반도체를 이용한 가스센서는 히터전극과 감지전극의 두 개의 전극을 가지고 있다. 제작된 센서는 히터전극위에 감지물질을 형성하여 단일 전극을 가지는 구조를 가지고 있다. 히터와 감지전극으로 사용되는 Pt는 glass 기판위에 스퍼터링법으로 형성하였으며, SnO_2 감지물질은 제작된 Pt 전극위에 열증착시켜 형성하였다. SnO_2막은 lift-off 공정을 이용해서 패턴을 형성하고 1시간 동안 산소분위기에서 열산화하였다. 제작된 소자의 크기는 1.92x.1 mm^2 이다. CO 가스에 대한 감지특성을 조사한 결과 1,000 ppm에 대해 100 mV의 출력변화를 나타내었으며, 넓은 농도범위(0 ~ 10,000 ppm에서 선형적인 전압출력을 나타내었다. 또한 가스 반응 전과 반응 후의 전압출력을 비교해 볼 때, 1 % 이내의 편차를 나타내는 우수한 회복성을 나타내었다. Micro gas sensor with single electrode was proposed for improving stability and sensitivity, Generally, metal oxide gas sensors have two electrodes for heating and sensing. This fabricated new type sensor have only a single electrode by forming a sensing material onto heating electrode. Pt as a heating and sensing electrode was sputtered on glass and a SnO_2 sensing material was thermally evaporated on Pt electrode. SnO_2 was patterned by lift-off process and then thermally oxidized in O_2 condition for 1 hr., 600 ℃. The size fabricated sensor was 1.9 x 2.1 mm^2. As a result of CO gas sensing characteristics, this sensor showed 100 mV change for 1,000 ppm and linearlity for wide range(0 ~ 10,000 ppm) of gas concentrations. And the sensor shows a good recovery characteristics of 1 % deviation compared to initial resistance.

      • KCI등재

        프리캐스트 콘크리트거푸집을 이용한 콘크리트기둥의 압축거동에 관한 연구

        정병주,홍갑표 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.1

        In the past, plywood formwork needed Various equipments, accessories, special labor, and complicate processes To use precast form, however, cuts down the process of formwork, the period of construction, the labor cost so It promotes productivity and economical efficiency Therefore, this paper aims for making clear the mechanical and structural rationality of using PC form m order to consult constructional convenience and economical efficiency To determine the compressional behavior and capability of PC form column, this paper compared and analyzed the experiment and analysis results The specimens are assorted the columns using box type PC form, the columns using channel type PC form, general block column, general brick columns, and general reinforced concrete columns The variable of the columns using the PC form are the thickness and space of wiremesh, the strength of filling concrete, the type of PC form The height of specimens is 60cm, the section is 30cm×30cm, the thickness of the PC form is 25cm, the main bar in filling concrete is D16, the tie bar is D10

      • 전립선 절제술 후 발생한 요실금의 치료에 인공 요도 괄약근의 효과

        김갑병,Stone, Anthony R. 대구효성가톨릭대학교 1997 연구논문집 Vol.55 No.2

        Purpose: A 10 year experience with the Artificial Urethral Sphincter(AUS) is reviewed to assess its efficacy and safety in treating postprostatectomy incontinence. Methods: Review of 65 patients' charts and telephone questionnarie was conducted by unbiased health care professional. Mean follow-up time is 28.0 months(2-114 months) 56 patients had prostate cancer(14 irradiated) and 9 had BPH. The initial surgery was radical prostatectomy in 51, transurethral resection in 14. 61 patients were evaluated by urodynamic preoperatively, confirming intrinsic sphincter deficiency, 22 patients exhibited detrusor instability and 12 had low compliance. On endoscopy, 7 patients had anastomotic contracture, necessitating pre-implantation incision. All patients had bulbous urethral cuffs(4.0 cm cuff in 4, 4.5 cm in 59, 5.0 cm in 1, 5.5 cm in 1) at the initial implantation. 62 patients were implanted with a 61-70 cm. reservoir, and 3 had a 51-60cm. device. Results: Delayed activation was employed in all. Before activation, 5 patients had intervention: 2 developed a peri-pump hematoma, 2 needed pump repositioning and one had pump malfunction. Following activation, 40 patients(62.5%) were continent, 18 patients(28%) had significant improvement, and 6(9.3%) were not improved. During follow-up, revision or explantation was required 19 times in 12 patients(19%): due to urethral atrophy under cuff site 6, inadequate reservoirs 5, pump malfunction 3, cuff leak 1, and infection 4(2 with erosion). Revision was required 6-43 months following implantation(average 16 months), and in most cases, continence was restored. Infection was always associated with urethral manipulation or revision. Revision rate was 40% in irradiated cases, compared to 17.6% in the rest. On questionnaire, 93.1% believed their continence was improved 86.7% were satisfied with device and 93.2% were willing to recommend AUS to friend, 90.9% of patients would undergo operation. Conclusion: The AUS is a safe and effective solution to post-prostatectomy incontinence. In the elderly and high risk population its revision and complication rate are acceptable.

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