컴퓨터에서 쉽게 즐길 수 있는 비행 슈팅게임의 설계

강상우, 김지윤, 안성옥, 김수균, 박동원 배재대학교 공학연구소 2014 공학논문집 Vol.16 No.1

슈팅 게임(Shoting game)은 액션게임에 속해 있는 장르중 하나로 총 또는 미사일 같은 원거리 무기를 사용해 공격과 적의 공격을 피하는 게임이며[1]‘비행슈팅(Aircraft Shooting)’은 비행기를 조작해서 싸우는 게임이다[2]. 비행슈팅게임은 누구나 게임에 대해 쉽게 이해하고, 쉽게 즐길 수 있기 때문에 다른 장르의 게임들에 비해 대중화 되어 있다. 본 게임은 컴퓨터에서 쉽게 즐길 수 있도록 설계된 게임으로 우주를 배경으로 제작된 게임이며, 수많은 운석과 기뢰들을 피하고, 게임 중반부에 나오는 해적선을 파괴하고 목적지까지 도달하는 것이 게임의 목표이다. 본 게임은 Unity3D를 이용하였고, Unity3D엔진은 다른 플랫폼과의 호완성이 좋고 자체 내에서 지원해주는 기능들이 많기 때문에 많은 개발자들이 사용하고 있다.

伏梁丸이 白血病과 肝癌患者에서 抽出한 癌細胞에 미치는 抗癌效果

金剛山,姜秉淇 圓光大學校 韓醫學硏究所 1991 원광한의학 Vol.1 No.1

To investigate the quantitative effect of an antitumor drug, Bokyangwhan(伏梁丸) which has been widely used in herb medicine area, rates of tumor cell death were measured by MTT colorimetric assay and ^3H-thymidine uptake analysis after treatment of tumor cell lines, K-562 derived from human myeloid leukemia and HEP-G2 and HEP-2 both derived from human hepatoma, with 1, 5 and 10% dconcentrations of Bokyangwhan(伏梁丸). The results obtained from this study were as follows. 1. The antitumor effect of Bokyangwhan(伏梁丸) observed in these three tumor cell lines were highly efficient showing 97% cell death in HEP-2, 93% cell death in HEP-G2 and 90% of cell death in K-562 when 10^5 cells/well were investigated. 2. An antitumor drug Bokyangwhan(伏梁丸) showed the very low survival rate of tumor cells as the concentration of Bokyangwhan(伏梁丸) increased(10% Bokyangwhan(伏梁丸) treated on the 3×10 exp(4) cell/well showed 70% cell death of K-562, 75% that of HEP-2 and 60% that of HEP-G2). 3. The antitumor effect of Bokyangwhan(伏梁丸) was smoehow different according to the different kinds of tumor cells showing 2% cell death of HEP-2, 17% that of HEP-G2 and 27% that of K-562 when 1% of Bokyangwhan(伏梁丸) was treated on the 2×10 exp(4) cell/well. 4. The antitumor effect of Bokyangwhan(伏梁丸) showed more sensitive to HEP-2 than HEP-G2 through all the concentrations observed, through both of these tumor cells were originated in the same organ, human liver(40∼50% of cell death were observed in HIP-G2 while 70% of that were observed in HEP-2 when 1% Bokyangwhan(伏梁丸) was treated). 5. The correlationship between MTT colorimetric assay and ^3H-thymidine uptake analysis was very strongly positive in all the cell lines observed among which K-562 showed most strongly correlative.

포르피린증 환자에서 보인 가역적 자기공명영상소견 1례

강석윤,마효일,곽규환,이상암 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

Paraquat 中毒에 대한 臨床的 考察

金剛山 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

Gamkutanggamibang(甘豆湯加味方) was adminstrated to a paraquat poisoned patient. The obtained results are as follows: 1. Paraquat poisoning caused depression to liver, kidney and the like. 2. The function of depressed liver and kidney were recovered since the adminstration of Gandutanggamibang(甘豆湯加味方) has two or three weeks. 3. Clinical symptoms induced by paraquat poisoning slowly disappeared since the adminstration of Gamdutanggamibang(甘豆湯加味方) has 3 weeks. It is concluded in this study that Gamdutanggamibang(甘豆湯加味方) has a good effect on a paraquat poisoned patient. From now on, I suggest, various herb medicines for poisoning should be ex-perimented and studied.

대합조개 배지에서의 세균증식

김정산,고광균,이강순 순천향대학교 1992 논문집 Vol.15 No.2

This study was performed to develop for korean products of culture medium which favors the growth of Vibrio vulnificus from the extract of a large clam(Meretrix lasoria). The new plating medium was tested for the growth of Vibrio vulnificus and their ability to form colonies compared with thiosulfate-citrate-bile salt-sucrose(TCBS) agar medium. The new medium was also tested for the growth of the members of the Enterobacteriaceae as well as Staphylococcus compare with MacConkey agar medium. 1. The growth of Vibrio vulnificus was excellent on clam agar as large colonies. 2. Most bacteria of the Enterobacteriaceae grow well on clam agar medium, on the other hand their were moderately inhibited on MacConkey agar medium. 3. The growth of Staphylococcus was highly inhibited on clam agar medium.

자궁경부 편평상피병소에서 인체유두종바이러스 감염과 Ki-67표출에 대한 연구

김창진,강상균,이종칠 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

The squamous cell carcinoma of the uterine cervix is the most common malignant tumor among women in Korea. Since 1976, when a research result that human papillomavirus(HPV) infection played some role in the tumorigenesis of the uterine cervical carcinoma had been published, numerous reports supporting the result has been released. They reported that about 90% of the carcinoma had some relation with HPV infections. About 20 subtypes of HPV has been observed in the anogenital lesions. As subtypes of the virus can be grouped into three according to the potentiality of malignant tumorigenesis, high risk group (HPV16, 18), intermediate risk group(HPV31, 33)and low risk group(HPV6/11), it is very important to identify the subgroups in the precancerous and cancerous lesions of the cervix for either diagnosis or prognosis. When HPV infects the epithelial cells, it promotes cellular proliferation. The cellular proliferation can be evaluated by immunohistochemistry with the antibodies for proliferting cell nuclear antigen(PCNA) and KI-67. Because PCNA has long half-life, and can be detected 48 hours after completion of mitosis, an estimation of proliferating cells by PCNA could be inaccurate. The expression of Ki-67 antigen is more correct than PCNA for the evaluation of proliferating cells due to its short half-life and rapid degradaton after completion of the mitosis. This study was conducted to see the relation between subtypes of HPV and cell proliferation by in situ hybridization(ISH) and immunohistochemistry in 60 cases of squamous intraepithelial lesions(SILs) and invasive carcinoma of the uterine cervix. The results are as follows; 1. HPV was detected in 50 out of 60 cases (83.5%). 2. The subtypes HPV6/11, the low risk group, were detected in 78.2% and 4.5% of low grade SIL and high grade SIL respectively, while not detected in any of invasive carcinomas. 3. The subtypes HPV 16, 18, the high risk groups, were detected in 4.3%, 59.1% and 80% of low grade SIL, high grade SIL and invasive carcinomas respectively. 4. In normal squamous epithelium and squamous metaplasia, the cell fraction expressing Ki-67 were 13.5%±6.7% and 8.7%±3.5%, while in low grade SIL, high grade SIL and invasive carcinomas they were 35.8±7.9%, 66.8±11.8% and 84±13.4% resepectively. 5. There was no relation between HPV subtypes and cell fractions expressing Ki-67. Above results shows that subtypes HPV6/11 are prevalent in low grade SILs, while HPV16, 18 are common in the high grade SIL and invasive carcinoma. It seems that there is no correlation between the cell fractions expressing Ki-67 and subtypes of HPV, which suggests that cellular proliferation can be induced by other than HPV infections. As the cell fraction expressing Ki-67 increases according to the grade of SIL and invasiveness, it would be useful prognostic factor along with the identification of high risk HPV type in the uterine cervical squamous epithelial lesions.

中風急性期에 活用되는 鎭肝熄風湯에 관한 臨床的 考察

沈廷燮,金剛山 대한동의병리학회 1998 동의생리병리학회지 Vol.12 No.1

최근 식생활의 변화와 노년층의 증가 등으로 中風이 증가하고 있어 동서의학적인 연구가 활발히 이루어지고 있다. 中風은 本虛表實證으로 인식되고 主風說, 主氣說, 主火說, 主痰濕說 등이 있으나 葉天士가 內風說을 개창한 이래 肝腸上亢, 肝腎陰虛 등에 의한 肝風內動이 주병기로 인식되고 있으며 內風은 양기가 음혈의 억제를 받지 못하여 과항하는 것이라 할 수 있다. 따라서 張錫純의 鎭肝熄風湯이 본 肝風內動證에 많이 사용되고 있으며 본 병원에서도 임상에 사용되고 있는 바 구체적인 치료효과에 대해 알아보고자 본 연구를 시행하였다. We studied the meaning and use of the Jingansickphungtang, so we found the Jingansickphungtang is effective of preventing early cerebral stroke. We had prescirbed the abstract of the Jingansickphungtang in 24 early cerebral stroke patients for six days from May, 1997 to December, 1997 and the results was as follows. 1. We observed recovering rates after a week; headache 72.7%, dizziness 75%, chest discomfort 83.3%, red face 93.7%, yawning sign 100%; average recovering rates 84.1%. 2. We observed the states of consciousness after a week. There were increasing from 20 patients to 23 patients in Gr.1 and decreasing from 4 patients to 1 patient in Gr.2. 3. We observed the states of swallowing after a week. There were increasing from 16 patients to 19 patients in having general diet and decreasing from 6 patients to 5 patients in having soft diet and decreasing from 2 patients to 0 patient in having liquid diet. 4. We observed the states of aphasia after a week. There were incresing from 7 patients to 16 patients in Gr.5 and decreasing from 13 patients to 4 patients in Gr.4. 5. We observed the states of motor weakness after a week. Upper limbdegeneration; 0 patient, changelessness; 13 patients(54.1%), improvement; 11 patients(45.9%) Lower limbdegeneration; 0 patient, changelessness; 12 patients(50%), improvement; 12 patients(50%) As the results, the Jingansickphungtang have effects in preventing of the most serious neurological symptomsmental disorder, dysphasia, aphagia and hemiparesis in early cerebral stroke.

白斑症의 文獻的 考察

朴庸權,金剛山 圓光大學校 韓醫學硏究所 1997 원광한의학 Vol.7 No.1

백반증(白斑症, Vitiligo)은 특발성 자가면역성에 의한 大小 各種의 局限된 범위의 피부멜라닌세포가 파괴된 상태로서, 색소가 脫失된 반(班)과 이를 둘어썬 과도색소침착이 보이며, 때로는 천천히 확대되기도 하는 질환이다. 백반증은 서양의학적인 용어이며, 한의학에서는 백전풍, 白駁風, 斑駁, 汗斑, 역양, 백전등으로, 일반인들은 백납이라 불리워지고 있다. 이에 본 연구에서는 古代에서 現代에 이르는 歷代 韓醫學書籍을 통하여 白斑症 및 白斑症 범주질환을 原因, 症狀, 治法, 治方으로 분류하고 정리한 결과 다음과 같은 결론을 얻었다. 1. 백반증은 一名 백전풍, 白駁風, 斑白, 汗斑, 역양, 白駁, 백납 등의 여러명칭으로 문헌에 기재되어 있었다. 2. 백반증의 原因은 風寒濕 등의 外因이나 七情內傷, 肺有壅熱 등의 內因들이 氣血不和를 일으켜 발생한다고 하였다. 3. 백반증의 증상은 面, 項部 등에서 주로 호발하며 白色斑點이 나타나고 疼痛이나 ??양감은 없었다. 4. 백반증의 治法과 治方은 內服藥이나 혹은 單用으로 外治法을 사용하는데 治方으로 浮萍丸, 蒼耳膏 등을 투여하거나 硫黃, 密陀僧 등의 약물을 外用으로 활용하고 있었다. In this study on Vitiligo, arranging seventeen kinds of separate volumes and papers published on Oriental medicine through the period from ancient to todays, I could get the result as folliws. 1. Vitiligo was writed several names such as begjunpung(백전풍), begbackpung(白駁風), banback(斑駁), hanban(汗斑), yuckyang(역양), begjun(반전) on literatures of oriental medicine. 2. The cause of Vitiligo is due to derangemint of Qui(氣) and Hul(血) caused exogeneous pathogenic factor such as Wind(風), Cold(寒) and Dampness(濕) or enogeneous pathogenic factor such as heat symptoms of the lung(肺有壅熱). 3. The symptom of Vitiligo may appear white-spot on face, neck area and have no pain, no itching sense. 4. The care of Vitiligo is classified as oral medication and external theraphy, and used the prescription- bupyunghwan(浮萍丸), changiego(蒼耳膏) or single drug-youhwang (硫黃), miltasueng(密陀僧).

扶正抗癌湯이 抗癌作用 및 免疫機能에 미치는 影響

최운영,김강산,강병기 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Bujeonghangam-tang(BHT) has been used in Oriental Medical Hospital of WonKwang University as a drug anti-cancer in recently. So, the purpose of this study was to investigate effect of BHT on the proliferation of anti-tumor, immunocytes and nitric oxide(NO) production from mice peritoneal macrophages. BHT consists of the following components ; Coicis semen(薏苡仁), Lilii bulbus(百合), Testudinis plastrum(龜板) Acanthopanacis cortex(五加皮), Ginseng radix(人蔘), Atractylodis macrocephalae rhizoma(白朮), Corni fructus(山茱萸), Asparagi radix(天門冬), Proraleae fructus(補骨脂). This study estimated the proliferation of L1210 cell lines, mouse thymocytes and mouse splenocytes and nitric oxide(NO) production from peritoneal macrophages in vitro. and estimated the proliferation of L1210 cells, thymocytes and splenocytes, NO production from peritoneal macrophages in L1210 cells-transplanted mice in vivo. The proliferation and cytotoxicity of cells was tested using a colorimetric tetrazoliun assay(MTT assay). The results of this study were obtained as follow ; BHT inhibited on the proliferation of L1210 cell lines in vitro and in vivo, and BHT was accelate nitric oxide prodution from peritoneal macrophages in vivo. This results sugest that BHT have anti-cancer action by NO production from peritoneal macrophages.

Trends and prospect of market of veterinary medical devices in Korea

Kyoung-Mook Kang(Kyoung-Mook Kang),Tae-Young Suh(Tae-Young Suh),Hwan-Goo Kang(Hwan-Goo Kang),Jin-San Moon(Jin-San Moon) 한국예방수의학회 2018 한국예방수의학회 학술대회자료집 Vol.2018 No.-