염색 단판을 이용한 集成 染色 무늬목 開發

안삼근,강형철,안상열,이균필,변희섭 경상대학교 농업생명과학연구원 2002 농업생명과학연구 Vol.36 No.4

본 연구는 집성 염색 무니목 개발을 위하여 사용 가능한 수종과 3종류의 염료를 사용하여 염색시간, 염색온도, 함수율 및 Flitch 제작에 대하여 연구한 결과는 다음과 같다. 실험에 사용한 4수종 중에서 선삭성이 불량한 은수원 사시나무를 제외한 3수종인 소나무와 이태리 포플러, 마티카가 사용 가능한 수종으로 밝혀졌다. Stain은 번지거나 얼룩이 지는 현상, Dylon은 침투 불균일로 부적당하였으나 Fine은 염색상태가 양호하였다. 염색시간은 5시간 이상 되어야 염색정도가 양호하였고, 염색온도는 90℃에서 가장 적당하였으며 생재와 기건재 및 포수재에 대한 영향은 큰 차이가 없었다. Flitch제작에 적당한 함수율은 9%이었다. This study was carried out to develop laminated dyeing wood, for which usable three sixties of trees and 3 kinds of dye stuffs were used to investigate dyeing time, dyeing temperature, moisture content and manufacture of flitch, the results were as follows: Out of four species of trees used in the experiment, it was found that three species, Pinus densiflora, Populus euramercana and Dyrea costulata were usable excluding Populus tomentiglandulosa whose cutting ability was bad. As to influence according to the kind of dye stuff, the Stain of low price could be used as a coloring agent but it was not proper as a dyeing agent due to spreading or staining phenomenon. As Dylon which was generally used to dye textile penetrated them uneven, dyeing only their surface, it was also found improper to be used. On the other hand, the dyed condition was good with Fine. The dyed condition was good when dyeing time was more than 5 hours and it was the most adequate when the temperature was at 90℃. There was no significant difference between their influence on green, dried and saturated wood.-In the manufacture of Flitch, the most appropriate moisture content was 9%.

국내 다기관에서 조사한 지역사회획득 메티실린내성 황색포도알균의 빈도와 임상적 특성

송진수,최평균,송경호,조재현,김성한,방지환,이창섭,박경화,박경운,신수,최희정,김의석,김동민,이미숙,박완범,김남중,오명돈,김의종,김홍빈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

목적 : 최근 전세계적으로 지역사회획득 메티실린내성 황색포도알균(community-associated methicillin-resistant Staphylococcus aureus, CA-MRSA)의 보고가 증가하고 있다. 하지만, 우리나라에서는 CA-MRSA 감염증에 대한 증례보고만 있을 뿐 아직까지 체계적인 연구결과가 없는 실정이다. 저자들은 국내에서 CA-MRSA의 빈도, 감염증의 임상적 양상, 분리된 균주의 항균제내성 양상을 조사하였다. 재료 및 방법 : 2005년 1월부터 2005년 6월까지 7개 병원에서 MRSA가 분리된 환자의 명단을 파악한 후 의무기록지와 건강보험심사평가원의 자료를 검토하였다. 외래나 응급실에서 혹은 입원 후 72시간 이내에 균주가 분리되고 MRSA 획득과 관련된 위험인자가 없는 경우 CA-MRSA로 정의하였으며, 분리된 균주의 임상적 의미에 따라 원인병원체(pathogen), 집락화(colonizer), 미결정(undetermined)으로 분류하였다. Penicillin과 oxacillin을 제외하고 3개 이상의 다른 계열 항균제에 내성이면 다제내성으로 정의하였다. 결과 : 연구기간동안 총 3,251주의 황색포도알균이 분리되었으며, 이 중 MRSA는 1,900주(58.4%)였다. MRSA 가운데 CA-MRSA는 114주(6.0%) 였으며, 이들이 분리된 부위는 귀(62주), 비뇨기계(14주), 피부 및 연부조직(11주), 호흡기계(10주), 혈액(3주) 등이었다. CA-MRSA 균주 가운데 집락균은 22주, 원인병원체는 22주였으며, 나머지 균주에 대해서는 그 임상적 의미를 결정할 수 없었다. 항균제 감수성 검사를 시행한 73균주 중 47주(64.4%)는 다제내성이었다. CA-MRSA 감염증 22예 중 피부 및 연부조직 감염(9예)과 중이염/외이도염(9예)이 가장 흔하였다. 침습적 감염증(invasive infection)은 4명(원발성 균혈증 3예, 감염성 관절염 1예)에서 확인되었지만, CA-MRSA 감염증으로 사망한 환자는 없었다. 결론 : 병원내 감염증에서는 MRSA가 심각한 문제이지만, 아직까지 지역사회 감염증에서 CA-MRSA는 흔하지 않았다. Background : Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. In Korea, little is known about the epidemiology and clinical features of community-associated MRSA (CA-MRSA). Material and Methods : Clinical microbiology laboratory databases of 7 hospitals were reviewed to identify the patients from whom MRSA was isolated during the period of January to July 2005. Only one isolate per patient was enrolled. In order to identify the risk factors of MRSA acquisition, the medical records and the Health Insurance Review Agency databases were reviewed. CA-MRSA was defined as MRSA isolated from patient without established risk factors. We analyzed patient demographics, underlying medical conditions, characteristics of infection, and antimicrobial susceptibility profiles. Results : Of total 3,251 S. aureus isolates, 1900 (58.4%) were MRSAs. Of the MRSA isolates, 114 (6.0%) were CA-MRSA. Of 114 CA-MRSA isolates, 22 (19.3%) were colonizers, 22 (19.3%) were pathogens, and the clinical significance of remaining 70 (61.4%) could not be determined. Median age of the 22 patients with CA-MRSA disease was 47 years. Nine patients had skin and soft tissue infections, 9 ear infections, 3 bacteremia, 1 septic arthritis. Seven patients had underlying medical disease. None died of the CA-MRSA infections. Of the 73 isolates of CA-MRSA, 47 (64.4%) were resistant to more than 3 classes of antibiotics besides β-lactams. Conclusion : Although MRSA is highly prevalent among hospital-associated S. aureus infection, CA-MRSA infections are not common.

골수구성 백혈병 환자에게 발생한 결핵성 림프절염

이창섭,송진수,최평균,조재현,방지환,박경화,박완범,김홍빈,김남중,윤성수,박선양,김병국,오명돈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

혈액질환 가운데 결핵 발생이 증가한다고 알려진 것은 호지킨 림프종을 포함한 림프증식성질환 그리고 모양세포성 백혈병 등이 있다. 또한 동종 골수이식을 받은 환자에서도 결핵은 증가한다고 알려져있다. Kaplan 등은 골수구성 백혈병 환자에서 결핵 발생이 증가한다고 보고하였다. 그러나 골수구성 백혈병 환자에서 결핵의 발생이 증가하는 이유에 대해서는 아직까지 정확하게 밝혀지지 않았다. 저자들이 2년 동안 후향적으로 조사한 180명의 성인 골수구성 백혈병 환자들 가운데 결핵이 발생한 환자는 4명이었고, 발생 부위는 모두 림프절이었다. 결핵은 골수구성 백혈병의 특정 아형에만 국한되어 발생하지 않았지만, 50%에서 FAB 분류에 의한 M4였다. 림프절이 종대된 골수구성 백혈병 환자에서 특히, 결핵의 유병율이 높은 나라에서는 결핵성 림프절염도 감별진단에 포함시켜야 한다. During the neutropenic phase, leukemia patients receiving chemotherapy are prone to bacterial and, fungal infections; occasionally mycobacterial, viral and protozoal organisms may also cause infections. Mycobacterium tuberculosis infection was reported very rarely in these patients. This report describes four patients with M. tuberculosis infection identified from 185 adult patients who were diagnosed myelogenous leukemia between January 2003, and December 2004. There was no patient with M. tuberculosis infection from 44 lymphoid leukemia and 11 acute biphenotypic leukemia patients. Sites of infection were all lymph nodes. Three among four patients were presented with lymphadenopathy at initial diagnosis of leukemia, and the other one presented with lymphadenopathy after induction chemotherapy. There was no patient presented with lymphadenopathy during the neutropenic phase. Tuberculous lymphadenitis was presented in a patient with three acute myelogenous leukemia (FAB class 2 M4, 1 M2) and a chronic myelogenous leukemia, accelerated phase. An acute myelogenous leukemia patient had a leukemic cell and tubercle bacilli in the same lymph node. Tuberculosis should also be included as a differential diagnosis in myelogenous leukemia patient with lymphadenopathy, especially in the countries in which the disease is endemic.

A NOTE ON IDEALS WHICH ARE MAXIMAL AMONG NONVALUATION IDEALS

KANG, BYUNG GYUN Korean Mathematical Society 1990 대한수학회지 Vol.27 No.1

Impact of Young Age at Diagnosis on Survival in Patients with Surgically Treated Renal Cell Carcinoma: a Multicenter Study

Kang, Ho Won,Seo, Sung Pil,Kim, Won Tae,Yun, Seok Joong,Lee, Sang-Cheol,Kim, Wun-Jae,Hwang, Eu Chang,Kang, Seok Ho,Hong, Sung-Hoo,Chung, Jinsoo,Kwon, Tae Gyun,Kim, Hyeon Hoe,Kwak, Cheol,Byun, Seok-Soo The Korean Academy of Medical Sciences 2016 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.31 No.12

<P>The prognostic significance of age in renal cell carcinoma (RCC) is a subject of debate. The aim of the present multi-institutional study was to evaluate the impact of age on clinicopathological features and survival in a large cohort of patients with RCC. A total of 5,178 patients who underwent surgery for RCC at eight institutions in Korea between 1999 and 2011 were categorized into three groups according to age at diagnosis as follows: young age (< 40 years, n = 541), middle-age (≥ 40 and < 60 years, n = 2,551), and old age (≥ 60 years, n = 2,096) groups. Clinicopathological variables and survival rates were compared between the three groups. Young patients had lower stage tumors with a low Fuhrman grade, a lower rate of lymphovascular invasion than patients in the other age groups. Regarding histologic type, the young age group had a lower percentage of clear cell histology and a greater incidence of Xp11.2 translocation RCC. Kaplan-Meier estimates showed that cancer-specific survival was significantly better in the young age group than in the other groups (log rank test, <I>P</I> = 0.008). However, age at diagnosis was not an independent predictor of survival in multivariate analysis. In conclusion, young age at diagnosis was associated with favorable pathologic features, although it was not an independent prognostic factor for survival in patients with surgically-treated RCC. Age itself should not be regarded as a crucial determinant for the treatment of RCC.</P>

Novel D–π–A structured Zn(<small>II</small>)-porphyrin dyes containing a bis(3,3-dimethylfluorenyl)amine moiety for dye-sensitised solar cells

Kang, Min Soo,Kang, Sung Ho,Kim, Sang Gyun,Choi, In Taek,Ryu, Jung Ho,Ju, Myung Jong,Cho, Daeheum,Lee, Jin Yong,Kim, Hwan Kyu The Royal Society of Chemistry 2012 Chemical communications Vol.48 No.75

<P>A high solar-to-electricity conversion efficiency of 7.22% was achieved with a short circuit current (<I>J</I><SUB>sc</SUB>) of 15.30 mA cm<SUP>−2</SUP>, an open circuit voltage (<I>V</I><SUB>oc</SUB>) of 669 mV and a fill factor (FF) of 0.71 for the 2Flu–ZnP–CN–COOH dye with a multi-functional co-adsorbent, under 100 mW cm<SUP>−2</SUP> AM 1.5 G simulated light.</P> <P>Graphic Abstract</P><P>A high photovoltaic efficiency of 7.22% was achieved with a <I>J</I><SUB>sc</SUB> of 15.30 mA cm<SUP>-2</SUP>, a <I>V</I><SUB>oc</SUB> of 669 mV and a FF of 0.71 for 2Flu-ZnP-CN-COOH with a multi-functional co-adsorbent, under 100 mW cm<SUP>-2</SUP> AM 1.5 G simulated light. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cc31384g'> </P>

The safety and efficacy of EGF-based cream for the prevention of radiotherapy-induced skin injury: results from a multicenter observational study

Kang, Hyun-Cheol,Ahn, Seung-Do,Choi, Doo-Ho,Kang, Min Kyu,Chung, Woong-Ki,Wu, Hong-Gyun The Korean Society for Radiation Oncology 2014 Radiation Oncology Journal Vol.32 No.3

Purpose: This study was designed to evaluate the efficacy and safety of topically applied recombinant human epidermal growth factor (rhEGF) for the prevention of radiation-induced dermatitis in cancer patients. Materials and Methods: From December 2010 to April 2012, a total of 1,172 cancer patients who received radiotherapy (RT) of more than 50 Gy were prospectively enrolled and treated with EGF-based cream. An acute skin reaction classified according to the Radiation Therapy Oncology Group 6-point rating scale was the primary end point and we also assessed the occurrence of edema, dry skin, or pruritus. Results: The percentage of radiation dermatitis with maximum grade 0 and grade 1 was 19% and 58% at the time of 50 Gy, and it became 29% and 47% after completion of planned RT. This increment was observed only in breast cancer patients (from 18%/62% to 32%/49%). Adverse events related to the EGF-based cream developed in 49 patients (4%) with mild erythema the most common. Skin toxicity grade >2 was observed in 5% of the patients. Edema, dry skin, and pruritus grade ${\geq}3$ developed in 9%, 9%, and 1% of the patients, respectively. Conclusion: Prophylactic use of an EGF-based cream is effective in preventing radiation dermatitis with tolerable toxicity. Further studies comparing EGF cream with other topical agents may be necessary.

A tunable carbon nanotube polarizer

Kang, Byeong Gyun,Lim, Young Jin,Jeong, Kwang-Un,Lee, Kyu,Lee, Young Hee,Lee, Seung Hee IOP Pub 2010 Nanotechnology Vol.21 No.40

<P>The electro-optic response of a carbon nanotube (CNT) cluster has been investigated. The cluster absorbs incident light before stretching. In the presence of an electric field, the cluster starts stretching along the field direction and contracts back to its original stage when the applied voltage is removed. The stretched cluster absorbs and transmits incident light with its electric vector propagating parallel and perpendicular to the long axis of the stretched cluster, respectively. Utilizing this selective light absorption property of a CNT cluster, a tunable polarizer or non-emissive light modulator can be realized. </P>

Cloning, Sequencing, and Expression of cDNA Encoding Bovine Prion Protein

KANG, SANG-GYUN,KANG, SUNG-KEUN,LEE, DEOG-YONG,PARK, YONG-HO,HWANG, WOO-SUK,YOO, HAN-SANG 한국미생물 · 생명공학회 2004 Journal of microbiology and biotechnology Vol.14 No.2

A normal prion protein (PrPc) is converted to a protease resistant isoform (PrPsc) by an apparent self-propagating activity in bovine spongiform encephalopathies (BSE), which is a neurodegenerative disease. The cDNA encoding bovine PrP open reading frame (ORF) in Korean cattle was cloned by polymerase chain reaction (PCR). The cloned cDNA had a length of 795 base pairs which coded for a protein of 264 amino acid residues with a calculated molecular mass of 28.6 kDa. Identities of 90,90,79 and 78% on nucleotide and 94, 94, 84, and 84% on amino acid sequence were shown to PrP genes from sheep, goat, human, and mouse, respectively. The cloned DNA was ligated into the pQE30 expression vector and transformed into E. coli M15. The PrP was expressed by induction with isopropyl-β-D-thiogalactoside (IPTG) and purified on the Ni-NTA affinity column. High specific activities of the recombinant PrP were observed in the fraction of pH 5.8 eluate and showed a molecular mass of -29 kDa on SDS-PAGE and Western blot analysis.

Centralized Control Algorithm for Power System Performance using FACTS Devices in the Korean Power System

Kang, Sang-Gyun,Seo, Sang-Soo,Lee, Byong-Jun,Chang, Byung-Hoon,Myung, Ro-Hae The Korean Institute of Electrical Engineers 2010 Journal of Electrical Engineering & Technology Vol.5 No.3

This paper presents a centralized control algorithm for power system performance in the Korean power system using Flexible AC Transmission Systems (FACTS) devices. The algorithm is applied to the Korean power system throughout the metropolitan area in order to alleviate inherent stability problems, especially concerns with voltage stability. Generally, control strategies are divided into local and centralized control. This paper is concerned with a centralized control strategy in terms of the global system. In this research, input data of the proposed algorithm and network data are obtained from the SCADA/EMS system. Using the full system model, the centralized controller monitors the system condition and decides the operating point according to the control objectives that are, in turn, dependent on system conditions. To overcome voltage collapse problems, load-shedding is currently applied in the Korean power system. In this study, the application of the coordination between FACTS and switch capacitor (SC) can restore the solvability without load shedding or guarantee the FV margin when the margin is insufficient. Optimal Power Flow (OPF) algorithm, for which the objective function is loss minimization, is used in a stable case. The results illustrate examples of the proposed algorithm using SCADA/EMS data of the Korean power system in 2007.