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Body Hair Scores and Total Hair Diameters in Healthy Women in Kirikkale Region, of Turkey
Nevin Sagsoz,Mansur Kamaci,Zerrin Orbak 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.SUP
It was aimed to determine the normal hair scores of women of Kırıkkale region according to the Ferriman- Gallwey scale and to investigate the relationship between the hair shaft diameter and hair scores. Hair scores were calculated in 204 healthy women, and hair shaft diameters were measured from the hair samples collected from 60 patients. Body mass index, waist to hip ratio, insulin resistance and blood androgen levels were determined. Neutral, hormonal and total hair scores were 2.1±1.4, 3.1±2.7 and 5.2±3.6, respectively. The average total hair diameter and hormonal hair diameter were 191.93±90.49μm and 121.8±75.9μm respectively. The correlation between total hair diameter and total hair score was statistically significant (r=0.704 p<0.001). Also, the correlation between hormonal hair diameter and hormonal hair score was statistically significant (r=0.724 p<0.001). While hair scores and diameters show meaningful positive correlation with androgen levels, they show negative correlation with age. In our population, 95% value of total hair score was 11, and for the hormonal score, it was 9. Hair diameters increase with hair score, regardless of total or hormonal of hair scores. Hair scores and hair diameters may be affected by blood androgens in healthy women.
The Effect of Insulin Like Growth Factor-1 on Recovery of Facial Nerve Crush Injury
Asuman Feda Bayrak,Yuksel Olgun,Ayla Ozbakan,Safiye Aktas,Can Ahmet Kulan,Gonca Kamaci,Emine Demir,Osman Yilmaz,Levent Olgun 대한이비인후과학회 2017 Clinical and Experimental Otorhinolaryngology Vol.10 No.4
Objectives. The aim of this study is to investigate the efficacy of locally applied insulin-like growth factor 1 (IGF-1) on the recovery of facial nerve functions after crush injury in a rabbit model. Methods. The rabbits were randomly assigned into three groups. Group 1 consisted of the rabbits with crush injury alone; group 2, the animals applied saline solution onto the crushed facial nerve and group 3, IGF-1 implemented to the nerve in the same manner. Facial nerve injury was first electrophysiologically studied on 10th and 42nd days of the procedure. The damage to the facial nerves was then investigated histopathologically, after sacrification of the animals. Results. In the electrophysiological study, compound muscle action potential amplitudes of the crushed nerves in the second group were decreased. In pathological specimens of the first and second groups, the orders of axons were distorted; demyelination and proliferation of Schwann cells were observed. However, in IGF-1 treated group axonal order and myelin were preserved, and Schwann cell proliferation was close to normal (P<0.05). Conclusion. Local application of IGF-1 in a slow releasing gel was found efficacious in the recovery of the facial nerve crush injury in rabbits. IGF-1 was considered worthy of being tried in clinical studies in facial nerve injury cases.