http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Kaizhao (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
Immune Effect of Newcastle Disease Virus DNA Vaccine with C3d as a Molecular Adjuvant
( Kai Zhao ),( Xutong Duan ),( Lianwei Hao ),( Xiaohua Wang ),( Yunfeng Wang ) 한국미생물생명공학회(구 한국산업미생물학회) 2017 Journal of microbiology and biotechnology Vol.27 No.11
Newcastle disease is a serious infectious disease in the poultry industry. The commercial vaccines can only offer limited protection and some of them are expensive and need adjuvants. At present, DNA vaccines are widely used. However, the immune responses induced by DNA vaccines are too slow and low. Here, we constructed the transfer vectors with a different number of C3d as molecular adjuvants (n = 1, 2, 4, or 6), and the vectors were cloned into the optimal eukaryotic expression plasmid (pVAXI-optiF) that expressed the F gene of Newcastle disease virus (NDV), and named pVAXI-F(o)-C3d1, pVAXI -F(o)-C3d2, pVAXI-F(o)-C3d4, and pVAXI-F(o)-C3d6, respectively. Cell transfection test indicated that pVAXI-F(o)-C3d6 showed the highest expression. In vivo immunization showed that the chickens immunized with pVAXI-F(o)-C3d6 intramuscularly induced better immune responses than the chickens immunized with the other plasmids. The protective efficacy of pVAXI-F(o)-C3d6 was 80% after challenge with the highly virulent NDV strain F48E9. The results in this study showed that C3d6 could be used as a molecular adjuvant to quickly induce an effective immune response to control NDV.
-
Study on Recycling Process for EOL Liquid Crystal Display Panel
Kai Zhao,Zhifeng Liu,Yulin Wang,Hao Jiang 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
As the popularity of liquid crystal display (LCD), the number of end-of-life (EOL) LCD panel is increasing sharply. In this case, how to recycle the resources that it contains and reduce the negative impact on the environment that it will produce has been a great challenge. This research, which was based on analysis of the structure features and material properties of LCD panel, divided the recycling process for EOL LCD panel into four parts, including the separation of two glass substrates, the extraction of liquid crystal,the separation of multi-layers film and polarizing film from glass substrate. Experiments were carried out based on the theoretical analysis so as to find out a desirable resolution to each part. Finally, the optimal and practical synthetic recycling process had been obtained so as to make sure that liquid crystal, indium resources, glass substrates and polarizer could be separated and sorted for recycling more effectively and help to promote the industrialization of recycling of EOL liquid crystal display panel.
-
Kai Zhao,Tao Yang,Mimi Sun,Wei Zhang,Yong An,Gang Chen,Lei Jin,Qinghua Shang,Wengang Song 한국분자세포생물학회 2017 Molecules and cells Vol.40 No.6
Interferon-γ-inducible protein 10 (IP-10), also known as chemokine C-X-C motif ligand (CXCL) 10, is closely associ-ated with antiviral immunity and the progression of chronic hepatitis B (CHB). However, the value of baseline serological and histological IP-10 expression levels in predicting the efficacy of the antiviral response to nucleoside/nucleotide analogues (NAs) is still unknown. In our research, intrahepatic and peripheral IP-10 expression levels were systemically examined before and after treatment with entecavir (ETV). Baseline serological and histological IP-10 expression levels were significantly increased in patients with CHB, particularly in patients with higher degrees of liver inflammation and liver fibrosis. Moreover, higher baseline intrahepatic IP-10 levels indicated better prognoses in patients with CHB after entecavir therapy. The baseline IP-10 level was also positively associated with several clinical parameters, including baseline levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), hepatitis B virus (HBV) DNA, and hepatitis B surface antigen (HBsAg), and with the decrease in HBsAg levels after treatment. In addition, monocyte-derived IP-10 was expressed at higher levels in patients with CHB than in patients with liver cirrhosis (LC) and healthy controls (HC). According to the results of our in vitro experiments, IP-10 directly promoted hepatocyte apoptosis. Based on these findings, baseline serological and histological IP-10 levels might predict CHB severity and the decrease in HBsAg levels after entecavir therapy.
-
ScienceON
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
