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Kim, Jin-Il,Yu, Jung Whey,Jahng, Yurngdong 영남대학교 약품개발연구소 1994 영남대학교 약품개발연구소 연구업적집 Vol.4 No.-
The synthesis and biological activity of ethyl (±)-7-(2-furyl)-cis-3, 5-dihydroxy-6-heptenoate were described.
Kim, Jin-Il,Yu, Jung Whey,Jahng, Yurngdong 영남대학교 약품개발연구소 1995 영남대학교 약품개발연구소 연구업적집 Vol.5 No.-
the synthesis and biological activity of ethyl (±)-7-(2-furyl)-cis-3, 5-dihydroxy-6-heptenoate were described.
Synthesis and Biological Activity of Conformationally Controlled 2-PAM Derivatives
Jahng, Yurngdong,Park, Jae Gyu,Yu, Jung Whey,Kim, Sun Young,Kim, Taean,Yang, Jae Ho 영남대학교 약품개발연구소 2000 영남대학교 약품개발연구소 연구업적집 Vol.10 No.-
A series of conformationally controlled 2-PAM derivatives were prepared from 2-acetylpyridine and 2,3-pyrido[b]cycloalkenones in two steps and their reactivities towards parathion poisoned AChE were evaluated. The most planar 2,3-pyrido[b]cyclohexanone oxime methiodide showed an activity comparable to 2-PAM implying E-syn is that the most active comformation of 2-PAM in the biological system.
Synthesis and Biological Activity of Conformationally Controlled 2-PAM Derivatives
Jahng, Yurng-Dong,Park, Jae-Gyu,Yoo, Jung-Whey,Kim, Sun-Young,Kim, Tae-An,Yang, Jae-Ho The Pharmaceutical Society of Korea 2000 Archives of Pharmacal Research Vol.23 No.3
A series of conformationally controlled 2-PAM derivatives were prepared from 2-acetylpyridine and 2,3-pyrido[b]cycloalkenones in two steps and their reactivities towards parathion poisoned AChE were evaluated. The most planar 2,3-pyrido[b]cyclohexanone oxime methiodide showed an activity comparable to 2-PAM Implying E-syn is that the most active comformation of 2-PAM in the biological system.