論文(론문) : 大腸正格證(대장정격증)과 장누수증후군(Leaky Gut Syndrome)과의 관계 考察(고찰)

이진철 ( Jin Cheoul Lee ),박상균 ( Sang Kyun Park ),방정균 ( Jung Kyun Bang ) 대한한의학원전학회(구 대한원전의사학회) 2013 대한한의학원전학회지 Vol.26 No.4

A Study on the Relationship between Dae-Jang-Jung-Gyeok(大腸正格) and Leaky Gut Syndrome Lee Jin-Cheoul1·Park Sang-Kyun2·Bang Jung-kyun3 *1Dept. of Medical History, College of Korean Medicine, Kyunghee University 2Dept. of Meridian, College of Korean Medicine, Sangji University 3Dept. of Korean Medical Classics and History, College of Korean Medicine, Sangji University Objective: If the penetration ratio of the intestinal mucosa is increased, the toxic or unhealthy materials - which should not be absorbed into our bodies - will be come into our bodies. They cause a sort of anti-toxic response or confusion of the immune system, and ultimately bring various types of diseases. This syndrome is related "Poison in Excrement" or "Internal Damage(內傷發□)" and Leaky Gut Syndrome, so I will study on the relationship between them. Method: Study on the relationship between Dae-Jang-Jung-gyeok and Leaky Gut Syndrome. Result: Korean doctors in ancient times called this syndrome "Poison in Excrement" or "Internal Damage(內傷發□)" and treated it with "Dae-Jang-Jung-Gyeok(大腸正格)". Leaky Gut Syndrome is a sort of clinical lesion, which allows foreign and harmful toxins in and results in a disorder of the immune system due to the leaking intestinal mucosa. Conclusion: Based upon the analyses, Dae-Jang-Jung-Gyeok and Leaky Gut Syndrome are closely related. Therefore diseases caused by the Leaky Gut Syndrome might be expected to be cured by Dae-Jang-Jung-Gyeok. Particularly the use of treatments for self-immune diseases and allergic diseases such as atopyic dermatitis and articular rheumatism should be expected to reveal a new path of treatment for other disorders such as Leaky Gut Syndrome. Key Words: Poison in Excrement, Internal Damage(內傷發□), Dae-Jang-Jung-Gyeok(大腸正格), Leaky Gut Syndrome

1,2-Benzisothiazol-3-one-1,1-Dioxide 유도체의 합성

정대일,정희철,변석인,이용균,박유미,최순규,한정태 東亞大學校附設基礎科學硏究所 2002 基礎科學硏究論文集 Vol.19 No.1

사카린 유도체는 제초제, 항독성, 살균제 등에 광범위하게 연구되어져 오고 있다. 새로운 농략 활성을 가진 물질을 합성하기 위해 먼저 선도물질로 사카린 1을 산화, 염소화 시킨 3-chloro-1,2-benzisothiazol-1,1-dioxide(BID-CI) 2와2cholromethy-1,2-benzisohizol-3-one1,1-dioxide 4를 합성하였다. 선도물질, amines, imidazoles, trones등과 반응시켜 다음과 같은 물질들을 얻었다. ; 3-cyclohexylamino-1,2-benzisothiazol-1,1-dioxide 6, 3-furylamino-1,2-benzisothiazol-1,1-dioxide 8, 3-(3-imidazol)-1,2-benzisothiazol-1,1-dioxide 10, 3-(2-methy-3-imidazol)-1,2-benzisothaizol-1,1-dioxide 12, 2-(3-imidazol)methy-1-1,2-benzisothiazol-3-one-1,1-dioxide 13, and 2-(-3-imidazol)methyl- 1,2-benzisothiazol-1,1-dioxide 14.

대전광역시 동⋅서지역 교육격차의 변화 모습

우중호(Jung-ho Woo),김도균(Do-kyun Kim) 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.15

목적 본 연구는 대전광역시의 동⋅서지역 교육격차에 영향을 미치는 생활 및 교육실태가 어떻게 변화하여 왔는지 분석하여 대전광역시의 교육격차를 보여주는 지표들이 어떻게 변화하고 있는지 알아보고자 한다. 또한 지역의 초등학교 교사 면담을 통해 교사들이 체감하는 교육격차의 변화 모습과 해결 방안에 대하여 함께 알아보고자 한다. 방법 통계청의 자료와 대전광역시교육청의 교육통계연보를 활용하여 대전광역시의 동⋅서지역의 생활 및 교육실태에 해당하는 지표들의 변화 모습을 알아보고, 대전광역시교육청 관내 초등학교에 근무하고 있으며, 동부와 서부의 학교에 모두 근무한 경험이 있는 초등학교 교사를 대상으로 초점집단면접(Focus Group Interview)을 통하여 교육격차의 변화를 고찰하여 교육격차 해소를 위한 방안을 제시하고자 한다. 결과 대전광역시 서부(서구, 유성구) 지역과 동부(중구, 동구, 대덕구) 지역의 생활 및 교육실태의 거의 모든 부분에서 동부가 서부보다 낙후되었으며 시간이 지날수록 생활 및 교육실태의 차이가 심화되고 있는 것으로 나타났다. 또한 대전광역시교육청 소속 초등학교 교사들은 대전광역시의 동⋅서지역 교육격차가 더욱 커짐을 직접적으로 체감하고 있었다. 결론 교육에 취약한 학생에 대한 보장 정책을 더 적극적으로 시행해야 한다. 지원 기준을 보다 세밀화하고 행정구역별, 학교별 교육 격차의 수준과 원인을 심도 있게 조사하여 학교 특성에 따른 맞춤형 지원이 될 수 있도록 해야 한다. 특히 기초학력 보장 정책의 연계성 있는 추진과 학생의 교육 경험의 확장, 가정 내 학생의 학습에 대한 관심도 제고 등과 같은 다각도의 접근이 필요하다. 마지막으로, 이 문제는 교육에 국한된 문제가 아니기 때문에 대전광역시의 현 상황을 모든 구성원들이 인식하고 함께 해결해나가야 할 문제임을 제언하였다. Objectives This study analyzes the living and educational conditions that affect the education gap in the eastern and western regions of Daejeon Metropolitan City, and tries to find out how the education gap in Daejeon is changing through interviews with local elementary school teachers. Methods In order to study the changes in living and educational conditions in the eastern and western regions of Daejeon Metropolitan City, data from the Statistics Korea and the Educational Statistical Yearbook of the Daejeon Metropolitan Office of Education were used. Also, a focus group interview was conducted on elementary school teachers. The target was a teacher who worked at an elementary school in the Daejeon Metropolitan Office of Education and had experience working at both schools in the east and west. Through FGI, We suggest a way to bridge the educational gap. Results The living and educational conditions of Seo-gu (Seo-gu, Yuseong-gu) and Dongbu (Jung-gu, Dong-gu, Daedeok-gu) of Daejeon Metropolitan City were analyzed. In almost all regions, the east was inferior to the west, and the difference was deepening over time. In addition, elementary school teachers felt that the educational gap between the eastern and western regions of Daejeon Metropolitan City was widening. Conclusions Guarantee policies for vulnerable students should be more aggressively implemented. Support standards should be refined and the level and causes of educational disparities by administrative district and school should be in-depth investigated so that customized support can be provided according to the characteristics of each school. In particular, it is necessary to take a multi-pronged approach, such as promoting policies that guarantee basic academic ability, expanding students' educational experiences, and raising students' interest in learning at home. Finally, since this problem is not limited to education, it is suggested that all members of Daejeon Metropolitan City should be aware of the current situation and solve it together.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

발열을 동반한 호중구감소증에서 Cefepime 단독투여와 Ceftazidime 및 Tobramycin 병합투여의 효능비교

정현욱,채제욱,강미라,양정채,문치숙,기현균,장현하,오원섭,김기현,백경란,이남용,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 국내에서 발열을 동반한 호중구감소증이 있는 악성 종양환자에게 경험적 항생제로 베타락탐계 항생제와 아미노배당체의 병합요법의 사용이 일반적이다. Cefepime은 광범위 항균 작용을 가지고 있어, 그람 음성균 뿐만 아니라 그람 양성균에 대해서도 우수한 효과를 나타낸다. 재료 및 방법: 발열을 동반한 호중구감소증이 있는 악성 종양환자를 대상으로 무작위, 공개, 비교 연구를 시행하였다. 대상 환자를 무작위로 cefepime 단독요법군과 ceftazidime 및 tobramycin 병합요법군으로 나누어 투여하고 각각의 임상적 효능과 안전성을 비교하였다. 구강및 인후 점막염이 있는 환자에서 분리된 녹색 연쇄알 구균에 대한 항생제 내성 정도를 조사하였다. 결과 : 대상환자 89명 중 CA 투여군이 48예(53.9%), CT 투여군이 41예(46.1%)이었다. 발열의 유형별로 MDI는 18예(20.2%), CDI는 9예(10.1%), UF는 62예(69.7%)로 두 군 간에 차이가 없었다. CA 투여군과 CT 투여군의 임상적 호전률은 시험약 투여 후 2-4일째 각각 91.7%, 85.4% (P=0.31), 치료 종료 시 각각 91.7%, 100% (P=0.15)로 두 군간에 유의한 차이가 없었다. 치료 종료 시 CA 투여군과 CT 투여군의 세균학적 소실률은 모두 100%로 두 군간의 유의한 차이가 없었다(P=0.78). 점막염이 있는 환자로부터 녹색 연쇄알 구균이 분리된 경우는 25예(28.1%)이었으며, 분리된 녹색 연쇄알 구균은 penicillin, ceftriaxone, cefepime, vancomycin에 모두 감수성을 보였다. 약제 관련 이상 반응의 발생 빈도도 두 군간에 유의한 차이가 없었다. 결론 : 발열을 동반한 호중구감소증이 있는 악성 종양환자의 경험적 항생제로서 cefepime 단독요법은 ceftazidime 및 아미노배당체의 병합요법만큼 효과적이고 안전하였다. Background : Broad-spectrum antibiotic therapy has been recommended as an empirical regimen in cancer patients with febrile neutropenia. Cefepime is a fourth generation cephalosporin with good activity against both gram-positive cocci and gram-negative bacilli. Materials and Methods : To compare the efficacy and safety of cefepime alone with ceftazidime plus tobramycin as empirical regimen for adult cancer patients with febrile neutropenia, a randomized, open label, comparative trial was performed. If the patient showed clinical improvent 72 hours, antibiotic could be changed to oral ciprofloxacin. Clinical and microbiological responses were determined at 72 hours and at the end of therapy. To investigate the antimicrobial resistance of viridans streptococci, swab cultures were obtained from throat in all enrolled patients and antimicrobial susceptibility tests were performed by using microdilution method according to the NCCLS. Results : A total of 89 patients were enrolled. Forty-eight patients received cefepime alone (CA), and 41 patients received ceftazidime plus tobramycin (CT). Demographic and baseline clinical characteristics were similar in both groups (P>0.05). The initial clinical success rate at day 2-4 in group CA (91.7%) was similar with that in CT group (85.4%) (P=0.31). At the end of therapy, the final clinical success rate in CA group (91.7%) was similar to that in CT group (100%) (P=0.15). In 18 patients, with microbiologically defined infections, the eradication rate was 100% in both groups. Adverse events including liver dysfunction (21.3%) and renal dysfunction (2.2%), were similar in both groups (P=0.87). Viridans streptococci were isolated from the throat cultures in 25 cases, and all of these strains were susceptible to penicillin (MIC_(90) 0.12 ㎍/mL), cefepime (1 ㎍/mL), and vancomycin (0.12 ㎍/mL). Conclusion : Efficacy and safety of cefepime monotherapy was comparable to the combination of ceftazidime and tobramycin. It could be used as an alternative empirical regimen for treating cancer patients with febrile neutropenia.

두개강내-외 혈관우회로 수술 후 과관류증후군

심정현,나형균,김성림,주원일,김문찬,최창락 The Korean Neurosurgical Society 2003 Journal of Korean neurosurgical society Vol.34 No.6

G.A 기반 디지털 디자인에 관한 고찰

박정대,김진균 대한건축학회 2004 대한건축학회논문집 Vol.20 No.11

This paper investigates one of the newest digital design methods in architecture to date: Genetic Algorithm(GA)-based generative growth system as a creative surface synthesis process to explore for new architecture. The paper consider aspects of design computation and discuss the new understanding that these have been approached in order to make computation useful in creativity of design. The digital design based on the GA in architecture has typical features that new structural morphology, the operative mechanism of the inheritance and variation, the population-based adaptive process and the design process with intended productivity.

全北地域의 人口의 長期 豫測 : A modle of Chonbuk

徐東均,朴正根 全北大學校 1990 論文集 Vol.32 No.-

In this paper the population of Chonbuk province is projected by the survival method. The population projection is the essential factor to establish the long-run developing plan for regional economy. The accuracy of the estimated population is required to accomplish the developing plan efficiently. The estimated population (1990-2001) will be 2,172,015(1990),2,169,948(1995) and 2,247,593(2001) respectively. In the characteristics of population structure, the portions of the young age(0―14) and the old age(60―) to the total population will be over 23% and 13% in 2001. The population structure of Chonbuk will change to the types of the developed country step by step. When the decrease of the young age group and the increase of the old age group are anticipated, the welfare plan for the old age will be gradually required. The rapid decrease of Meon-level population results in the lack of labor forces in rural area. The counterplan to it should be considerated.

기초자치단체 행정정보공개에 관한 연구 : 수요자 및 공급자 만족도를 중심으로

우정수,임태균 인제대학교 2010 仁濟論叢 Vol.25 No.1

This study analyzes the way local governments in Gyeongsangnam-do discloses its administrative information to the public-the methods and the style-and examines the factors that affect the information suppliers‘ satisfaction and demanders’ satisfaction in order to suggest possible policy solutions. The study showed that six major factors influence the information suppliers’ satisfaction of information disclosure, respectively: relevance of information disclosure criteria (β =0.3), relevancy of information disclosure organization (β =0.219), unsoundness of information request (β =-0.179), correspondence between requested information and provided information (β =0.157), effectiveness of information disclosure (β =0.093), and pertinence of information disclosure service (β =0.091). On the other hand, the factors affecting demanders’ satisfaction were correspondence between requested information and provided information(β =0.381) , pertinence of information disclosure service handling(β =0.352), the government employees' kindness(β=0.145), and relevance of information disclosure criteria(β =0.116)

프랭크 게리의 디지털 디자인 프로세스에 관한 연구

박정대,김진균 대한건축학회 2004 대한건축학회논문집 Vol.20 No.10

The purpose of this paper investigates one of the digitally adapted design methodologies in architecture. Reverse Engineering(RE)-based digital design process as surface representation process to construct a complex free-from shape and explore for new architecture. The paper takes as its objective of inquiry a specific set of building intentions, and associated computational strategies, playing a fundamental role in Gerhy's projects the design, engineering and fabrication of surface forms. The digital design process in Frank O Gehry's architecture has typical features that new geometry, structural skin, not mass production but mass customization, new role-model of architect as master builder and cultural transition to collaborative partnerships.