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Prognostic impact of hepatitis B or C on intrahepatic cholangiocarcinoma
Jung Woong Seo,Byung Soo Kwan,Young Koog Cheon,Tae Yoon Lee,Chan Sup Shim,So Young Kwon,Won Hyeok Choe,Byung Chul Yoo,Jeong Min Yoon,Jung Hoon Lee 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.3
Background/Aims: Intrahepatic cholangiocarcinoma (ICC) is the second-most common primary liver malignancy, arising from the peripheral intrahepatic bile duct epithelium. Hepatitis B virus (HBV) or hepatitis C virus (HCV) may be involved in the development of ICC. We explored the prognostic value of hepatitis virus infection, as well as other prognostic factors affecting survival in patients with ICC. Methods: A retrospective chart review was performed for patients diagnosed with ICC between August 2005 and December 2018 at Konkuk University Medical Center. We identified a total of 131 patients with ICC. Overall survival rates of patients with and without hepatitis were determined. Univariate and multivariate analyses were used to estimate factors influencing survival outcomes. Results: A total of 17.6% (23/131) of patients were positive for HBV or HCV. Hepatitis B positive ICC patients were significantly younger with higher albumin and higher α-fetoprotein than those without hepatitis viral infections. The median survival of hepatitis-positive and hepatitis-negative groups was 280 and 213 days, respectively. Survival rates were not significantly different between the two groups (p = 0.279). Multivariate analyses indicated that lower serum carbohydrate antigen 19-9 (CA 19-9) (p < 0.001), lower T stage (p = 0.042), the absence of lymph-node metastasis (p = 0.043), and receiving curative surgery (p = 0.033) were independent predictors of better outcomes. Conclusions: While hepatitis influenced a number of clinical features in ICC patients, it did not affect survival rate. Prognostic factors influencing survival outcomes with ICC were CA 19-9 level, T stage, the presence of lymph node metastasis, and curative surgery.
Properties of Detection Matrix and Parallel Flats fraction for $3^n$ Search Design+
Um, Jung-Koog The Korean Statistical Society 1984 Journal of the Korean Statistical Society Vol.13 No.2
A parallel flats fraction for the $3^n$ design is defined as union of flats ${t}At=c_i(mod 3)}, i=1,2,\cdots, f$ and is symbolically written as At=C where A is rank r. The A matrix partitions the effects into n+1 alias sets where $u=(3^{n-r}-1)/2. For each alias set the f flats produce an ACPM from which a detection matrix is constructed. The set of all possible parallel flats fraction C can be partitioned into equivalence classes. In this paper, we develop some properties of a detection matrix and C.
정성국(Jung-Sung Koog) 대한치과의사협회 2021 대한치과의사협회지 Vol.59 No.2
Regeneration of interdental papilla damaged by periodontal disease has been a very challenging task. Up until now, many dentists have devised and introduced great surgical methods. When I compared the pros. and cons. Of these many methods, I came up with the best way to regenerate interdental papilla. Temporarily creating space between narrow interdental papilla, which could not be solved by periodontal surgery alone, was a great help for connective tissue graft (CTG). The CTG was performed using a microblade, and only one vertical incision was required from the gingival margin. The graft was then performed by inserting the grafts through this incision. Along with the orthodontic treatment, the area between the narrow interdental papilla was widened, which made it easier to carry out the CTG. After a period of maintenance, I was able to bring the teeth together again using orthodontic force and regenerate the interdental papilla. I named this method the ELSA (Enlargement of space - Labial graft - Squeezing - for Augmentation of papilla) technique.
Alias Component Permutation Matrices (ACPM) for the $3^n$ Parallel Fractional Factorial Design
Um, Jung-Koog The Korean Statistical Society 1980 Journal of the Korean Statistical Society Vol.9 No.1
A parallel flats faraction for the $3^n$ factorial experiment is symbolically written as $At = C(r\timesf)$ where $A(r\timesn)$ is of rank r. The A-matrix partitions the nonnegligible effects into $(3^{n-r}-1)/2+1$ alias sets. The $U_i$ effects in the i-th alias set are related pairwise by elements from $S_3$, the symmetric group on three symbols. For each alias set the f flats produce an $f \times u_i$ alias componet permutation matrices (ACPM) with elements from $S_3$. All the information concerning the relationships among levels of the effects is contained in the ACPM.
A Detection Matrix for $3N^n$ Search Design
Um, Jung-Koog The Korean Statistical Society 1983 Journal of the Korean Statistical Society Vol.12 No.2
A parallel flats fraction for the $3^n$ factorial experiment is defined as the union of flats, ${t$\mid$At=C_i(mod 3)}, i=1,2,\cdot,f$, in EG(n,3) and is symbolically written as At=C where A is of rank r. The A matrix partitions the effects into u+1 alias sets where $u=(3^{n-r}-1)/2$. For each alias set the f flats produce an alias component permutation matrix (ACPM) with elements from $S_3$. In this paper, a detection vector of the ACPM was constructed for each combination of k or fewer two-factor interactions. Also the relationship between the detection vectors has been shown.
Number of Equivalence Classes of a Parallel Flats Fraction for the 3" Factorial Design
Um, Jung-Koog The Korean Statistical Society 1981 Journal of the Korean Statistical Society Vol.10 No.-
A parallel flats fraction for the $3^n$ factorial is symbolically written as $At=C=(C_1 C_2 \cdots C_f)$ where C is a rxf matrix and A is rxn matrix with rank r. It is shown that the set of all possible parallel flats fraction C for a given A and given size can be partitioned into equivalence classes. The number of those classes are enumerated in general.
Search Design of Resolution III.2 for $3^n,n=4,5,6^+$
Um, Jung-Koog 韓國統計學會 1988 Journal of the Korean Statistical Society Vol.17 No.2
The basic conditions for a parallel-flats fraction to be a search design of Resolution III.2 have been developed in Um (1980, 1981, 1983, 1984). In this paper, a series of resolution III.2 search designs for $3^n, n=4, 5, 6$, are presented.
On the Srivastava's Theorem for the search design.
Um, Jung-Koog The Korean Statistical Society 1980 Journal of the Korean Statistical Society Vol.9 No.2
In this paper, Srivastava's Theorem for the search design is considered, with additional assumptions, to the $3^n$ parallel flats fractions. It is also expressed in terms of ACPM.
Search Design of Resolution III.3 for $3^4$Factorial
Um, Jung-Koog 韓國統計學會 1990 Journal of the Korean Statistical Society Vol.19 No.1
The basic conditions for a parallel flats fraction to be a search design of resolution III.2 have been developed in Um (1980, 1981, 1983, 1984). A series of resolution III.2 search design for $3^n, n=4, 5, 6$ are presented in Um (1988). In this paper a resoultion III.3 search design for $3^4$ is presented.
( Hae Jung Song ),( Jin Oh Kim ),( Soo Hoon Eun ),( Young Deok Cho ),( In Seop Jung ),( Young Koog Cheon ),( Jong Ho Moon ),( Joon Seong Lee ),( Moon Sung Lee ),( Chan Sup Shim ),( Boo Sung Kim ),( So 대한소화기학회 2007 Gut and Liver Vol.1 No.1
Background/Aims: Distinguishing benign and malignant lymph nodes by the findings of endoscopic ultrasonography (EUS) is still controversial. We tried to evaluate EUS findings of benign mediastinal and abdominal lymphadenopathy (BLAP) confirmed by EUS-guided fine needle aspiration (FNA). Methods: A total of 37 patients with enlarged mediastinal or abdominal lymph nodes (diameter ≥1 cm) were enrolled and EUS-FNA was performed. Final diagnosis was based on FNA cytology and follow up imaging studies (CT scans or EUS). Results: Thirteen patients were confirmed to have BLAP by EUS-FNA. Causes of BLAP were as follows; (i) extrapulmonary tuberculosis in six cases including patients with postoperative states due to cervical cancer and advanced gastric cancer, (ii) Kikuchi disease in one case, (iii) hypereosinophilic syndrome in one case, (iv) reactive hyperplasia in five cases including patients with postoperative states due to thyroid cancer, lung cancer, and EGC with ESD. EUS findings of BLAP revealed that median lymph node size was 24.7 mm. Lymph nodes were oval or round shaped in 9 cases, sharp borders in 9 cases, hypoechoic echo pattern in 7 cases, heterogenous internal echo pattern in 7 cases. Other findings included internal septation, calcification, multiplicity, attachment to the gastrointestinal tract wall, and conglomeration. Conclusions: EUS findings of BLAP were not different from those of malignant lymphadenopathy previously reported in other studies. (Gut and Liver 2007;1:68-73)