Chemical Constituents of Essential Oils Possessing Anti-Influenza A/WS/33 Virus Activity

Hwa-Jung Choi 질병관리본부 2018 Osong Public Health and Research Persptectives Vol.9 No.6

Osong Public Health Res Perspect > 9(6); 2018 > Article Original Article Osong Public Health and Research Perspectives 2018;9(6):348-353. DOI: https://doi.org/10.24171/j.phrp.2018.9.6.09 Chemical Constituents of Essential Oils Possessing Anti-Influenza A/WS/33 Virus Activity Hwa-Jung Choi* Department of Beauty Science, Kwangju Women’s University, Gwangju, Korea *Corresponding author: Hwa-Jung Choi, Department of Beauty Science, Kwangju Women’s University, Gwangju, South Korea, E-mail: rerived@kwu.ac.kr Received April 30, 2018 Revised November 23, 2018 Accepted November 27, 2018 Copyright ©2018, Korea Centers for Disease Control and Prevention (open-access, http://creativecommons.org/licenses/by-nc-nd/4.0/): This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Objectives This study was conducted to determine whether essential oils had anti-influenza A/WS/33 virus activity and whether there were specific compounds associated with this activity. Methods There were 63 essential oils evaluated for anti-influenza (A/WS/33 virus) activity using a cytopathic effect reduction method. The chemical composition of the anti-influenza essential oils was phytochemically analyzed by gas chromatography-mass spectrometry. Results The antiviral assays demonstrated that 11 of the 62 essential oils (100 μg/mL) possessed anti-influenza activity, reducing visible cytopathic effects of influenza A/WS/33 virus activity by > 30%. Furthermore, marjoram, clary sage and anise oils exhibited anti-influenza A/WS/33 virus activity of > 52.8%. However, oseltamivir (the anti-influenza A and B drug), showed cytotoxicity at the same concentration (100 μg/mL) as the essential oils. The chemical composition detected by GC–MS analysis, differed amongst the 3 most potent anti-viral essential oils (marjoram, clary sage and anise oils) except for linalool, which was detected in all 3 essential oils. Conclusion This study demonstrated anti-influenza activity in 11 essential oils tested, with marjoram, clary sage and anise essential oils being the most effective at reducing visible cytopathic effects of the A/WS/33 virus. All 3 oils contained linalool, suggesting that this may have anti-influenza activity. Further investigation is needed to characterize the antiviral activity of linalool against influenza A/WS/33 virus.

축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

유가증권시장 상장기업의 선택적 회계처리에 관한 실태 분석

이병화 ( Lee Byung-hwa ),윤우영 ( Yun Woo-young ),정원일 ( Jung Won-il ) 한국세무회계학회 2017 세무회계연구 Vol.0 No.52

본 연구는 한국거래소 유가증권시장에 상장된 기업의 유형자산과 재고자산의 선택적 회계처리에 관한 실태 분석이다. 유형자산의 평가모형 및 감가상각방법 분석결과 유형자산의 평가모형 중 원가모형을 적용하고 있는 회사는 전체 728개 중 659개(90.5%), 64개(8.8%)가 원가모형과 재평가모형을 함께 적용하고 있다. 재평가모형을 적용하는 유형자산은 대부분 토지로 나타나고 있으며, 재평가모형만을 적용하는 회사는 없는 것으로 나타났다. 유형자산의 감가상각방법 중 정액법을 적용하고 있는 회사는 전체 728개 중 709개(97%), 정액법과 정률법을 함께 적용하는 회사는 11개(1.5%), 정액법과 생산량비례법을 함께 적용하는 회사는 2개, 정률법만 적용하는 회사는 1개 회사로 나타났다. 그리고 3개 회사는 유형자산 계정과목이 없으며, 2개 회사는 감가상각방법에 대한 내용이 주석에 공시되지 않고 있다. 재고자산의 수량결정방법과 가격결정방법을 분석한 결과 재고자산의 수량결정방법으로 계속 기록법과 실지재고조사법을 함께 적용하고 있는 회사는 728개 중 68개(9.3%), 실지재고조사법만 적용하는 회사는 3개, 계속기록법만 적용하는 회사는 1개 회사이다. 나머지 548개(75.3%) 회사는 주석에 수량결정방법을 공시하지 않고 있다. 재고자산의 가격결정방법은 회사들이 기업의 환경에 맞게 재고자산의 유형에 따라 다양하게 적용하고 있으며, 업종의 특성에 따라 금융업과 서비스업 중 지주회사에 해당하는 기업에서는 재고자산 계정과목이 재무상태표에 나타나지 않고 있으며, 유통업에서는 소매재고법(매출가격환원법)을 적용하는 회사가 9개 회사로 나타났다. 유형자산의 경우는 업종 특성에 관계없이 대부분의 회사가 평가모형으로 원가모형, 감가상각방법으로 정액법을 사용하고 있으며, 이와 달리 재고자산의 경우는 기업의 상황과 업종 특성을 반영하여 다양한 가격결정방법을 사용하고 있는 것으로 판단된다. This study is an analysis on the realities on the selective accounting of property, plant and equipment and inventories of listed firms in KOSPI. As a result of analyzing the evaluation model and depreciation method of property, plant and equipment, 659 firms(90.5%) out of the total 728 firms that applied cost model. and 64 firms(8.8%) applied cost model and revaluation model. Most of the property, plant and equipment applying the revaluation model are shown as land, and no firm applies the revaluation model. Among depreciation methods of property, plant and equipment, 706 firms(97%) of the total 728 firms that apply the straight-line method, 11 firms(1.5%) to apply the straight-line method and the fixed percentage method. There are two firms that apply the straight-line method and activity method, one firm that applies only the fixed percentage method. The three firms do not have a property, plant and equipment account and the two firms do not disclose depreciation methods in the footnotes. As a result of analyzing the method of determining the quantity of inventories and the method of determining the price, 68 firms(9.3%) of the 728 firms that applied perpetual inventory system and periodic inventory system. There are three firms that applies only periodic inventory system, and one firm that applies only perpetual inventory system. The remaining 548 firms(75.3%) do not disclose how to determine the amount in the financial statements footnotes. The method of determining the price of inventories varies according to the types of inventories according to the firm`s environment. According to the characteristics of the industry, firms in the financial and service industries that are holding companies do not show inventory account in their financial statements. In the retail industry, six firms apply the retail inventory method.

도시공원 녹지의 점유면적 분석 : 대구시를 중심으로

사공정희,나정화,이정민 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

The objective of this research was to clarify the park area per person in Daegu and to provide the data for distributing the park area with each zone evenly. The results were as follows; 1) The types of green space were classified to 52 classes in forest area, agriculture area and developed area. 2) The analysis of gthe park area per person, at the 9 dong was presented over area 6㎡ and at any dong was presented below 1㎡ area or no green space. 3) The park area rate was presented at the highest in Dalsung-gun, 26.7% and at the lowest in Nam-gu, 1.2%. In comparison to urban park area rate in Daegu 8.9%, over rate was presented 3 zone and in the rest zones were presented below 6%. We concluded that concentration of the park area rate in some zone was serious.

췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

대구시 소방권역별 접근성 분석을 이용한 구조대 재편방안

정규동(Jung Gyu-Dong),홍원화(Hong Won-Hwa),최준호(Choi Jun-Ho),김광섭(Kim Gwang-Seob),이지수(Lee Ji-Soo) 대한건축학회 2012 대한건축학회논문집 Vol.28 No.9

In a fire situation, the priority is fast and safe rescue. Therefore, because of the importance of the role of rescue team, specify the criteria of equipments as act. But it can’t be helped appear vulnerable area according to the problems such as province fiscal conditions and budget. in this study suggest improvement considering the characteristics of the actual road and emergency vehicles through accessibility analysis. In the process of vulnerable area deduction, the area of service area is wider, the larger number of vulnerable buildings. And analyze that especially approximately 77% of the entire are vulnerable buildings. Jung-gu, Daegu, the center of the approach is only 3% of vulnerable buildings, but as a whole of Daegu, Within 5 minutes from the rescue team are difficult to access the building by about 30 percent. In order to improve it, Station of jurisdiction that need to be adjusted or additional installations proposed regional strategy for the reorganization. According to the proposed strategy to evaluate the improvement, vulnerable about the whole building from 140,000 to 70,000 could be reduced by half. Alternative to reduce the vulnerability of buildings according to the percentage reduction in overall approximately 30-16% can be reduced. If use the result of study, it will be able to set priorities of expansion of rescue team, and utilized to predict macroscopic vulnerable area in Daegu city.

골분을 이용한 구리 흡착 첨착

김은정,박정훈,김정섭,유현철,이봉섭,곽명화,우성훈,박승조 東亞大學校 環境問題硏究所 2005 硏究報告 Vol.27 No.1

Spent pig bone was consist of hydroxyapatite. And then we thought that it have a possibility as a adsorbent. The preparation of bone char prepared from spent pig bone in this study. We study on the recycling possibility as a adsorbent is able to adsorb copper ion from their single aqueous solutions. The results are summarized as follows. Bone char that prepared from spent pig bone at 105, 400, 700℃. The adsorption removal efficiency of copper ion onto bone char as adsorbent was above 90% for 15 hours. Increase in the initial pH of the copper ion solution result in an increase in the copper ion uptake per unit weight of the adsorbent. Freundlich isotherm model was found to be applicable for the experiment data of copper ion. The results showed that spent pig bone can be used for the absorption of the copper ion.

초등학교 아동을 위한 리더십 프로그램 개발

김정효,정인숙,김신래,엄화정 이화여자대학교 교육과학연구소 2007 교육과학연구 Vol.38 No.3

학교교육과정에서는 자율성의 확대에 밀려 타인배려와 공동체에 대한 책임의식 교육은 상대적으로 열세의 위치에 처해있다. 그러나 21세기 정보화 산업구조에서는 한개인에게 리더이자 동시에 멤버로서의 역할을 요구하고 있다. 특별히 학령기 아동에있어서는 또래 집단 형성이라는 사회성 발달 과업의 특성이 초등학교아동기에 ‘자신이가진 독특한 자질을 발휘하여 공동체의 유익을 위해 영향을 발휘할 수 있는 능력’ 으로서의 리더십 교육을 필요로 한다. 본 연구에서는 자신자질에 대한 이해를 기반으로 자신감을 가지도록 하는 심리적요소, 자신 뿐 아니라 공동체의 유익을 중요한 삶의 목적이 되어야 한다는 가치적 요소, 그리고 의사소통능력, 대인관계기술 등의 기술적 요소를 기반으로 하는 초등학교고학년 아동을 위한 5일간의 단기 리더십 프로그램을 개발하였다. 서울 시내 한 사립초등학교 5학년을 대상으로 형성평가를 위한 예비실행연구를 하였고, 아동의 자기평가와 교사와의 면담을 통해 개발된 리더십프로그램은 대체로 심리적, 가치적, 기술적요소에 효과를 가지고 온 것으로 보였다. 특히 리더십이란 특정 개인에게만 있는 것이아니라 모두에게 잠재되어 있다는 인식의 전환을 가져옴으로써 자신감과 리더십 개념획득에 두드러진 효과를 가지고 오는 것으로 보였다. This study is to develop a leadership program for elementary school children. Due to extension of freedom, education of responsibility such as taking care ofothers and consideration of community is inferior in the school education. However, in information-oriented society asks for an individual to become aleader and a member at the same time. In addition, specific character of creatingpeer group in children of school age makes it more necessary educate "ability todisplay individual's specific quality for benefit of community". In this study, based on including psychological factor to understand themselvesto bring their confidence, value factor that benefit for the community has to bethe reason for their life and technological factors such as communicating skillsand interpersonal relationship, 5day short-trial for senior students of elementaryschool was developed. A preliminary inspection was held to 5th graders in anelementary school in Seoul. In result, our leadership program gave positive effecton psychological factor, value factor and technological factors. Especially, thisprogram was effective to give confidence and rearranged the definition ofleadership by the idea that leadership is not for the certain individuals buteveryone has their potentials.

仁川 이미지 提高를 위한 都市 마케팅 戰略

朴正華(Park, Jung-Hwa) 청운대학교 관광산업연구소 2012 관광산업연구 Vol.6 No.1

As the era of local autonomy emerged, the authority and role of the city government began to expand in 1995 and the importance of a city’s competitiveness increased in today’s age of globalization. Realizing the importance of a differentiation strategy for the advancement of regional development, local governments are now actively adopting and promoting city marketing strategies for their cities. Incheon’s image is mainly associated with an international airport and an international distribution center, and its image is slowly changing into that of a high tech city. Incheon is a place where traditional and modern times coexist. While the city is rapidly turning into a place with modern city appearances with Youngjong-do’s international airport and Song-do’s development into a cosmopolitan city Jung-gu and Dong-gu, which were the origins of modern Incheon, are still left unattended and unorganized. Like Ganghwa, Incheon, a place of traditional cultures, is capable of recreating itself as a city of modernization with the help of migrated artists’ influences. Instead of insisting on a particular cultural identity, Incheon must use a differentiation strategy by specializing unique cultural backgrounds and characteristics pertinent to each distinct region. To achieve these objectives as Incheon’s city marketing strategy, Incheon should take the following steps: first, enhance a differentiation strategy from other local cities by establishing prioritizedcity marketing policies second, establish a strategy utilizing its natural resources and cultural heritages; third, seek to actively promote cultural marketing of Jung-gu’s chinatown’s events in Incheon, which is turning into a multicultural society; fourth, establish Incheon’s city marketing strategy which effectively applies cultural events and festivals.

고등급 이형성을 보인 편평톱니샘종

권경주,정성애,심기남,정정화,강석형,송도경,전승정,김혜인 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1

Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some hyperplastic polyps with serrated morphology of the crypts have been recognized to have distinctive features and these polyps were termed ‘serrated adenomas’. Recent data show that sessile serrated adenomas (SSA) might be the precursors of serrated colonic cancers, underlining the necessity of identifying them. SSA is approximately 3% of all polyps, commonly appears as flat or sessile and yellowish due to mucus production. In the pathogenesis of SSA, progression to high grade dysplasia or early invasive carcinoma may be associated with serrated neoplasia pathway different from adenoma-carcinoma sequence. We report a case with a colon polyp diagnosed as sessile serrated adenoma with high grade dysplasia after endoscopic submucosal dissection.