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크롬 노출 근로자의 말초혈액 임파구내 소핵출현에 관한 연구
김해준,나중호,김영환,최재욱 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.3
Objectives: The goal of this study is to observe the associations between the chrome concentrations (blood and urine) and number of lymphocyte with micronuclei among workers exposed to chrome. Additionally to test appropriateness of micronuclei test for biologic monitoring markers such as urine or blood chrome. Methods: Twenty-seven pairs of subjects exposed to chromate environment and non-exposed were matched with age and smoking habit, and all subjects were composed of male workers only. Results: In control group, age-related increment in number of cultured lymphocytes with micronuclei was observed statistically significant. But, in exposed group, similar results were revealed without statistically significance. Number of lymphocytes with micronuclei was significantly increased with the increment of blood or urinary Cr concentration. The number of lymphocytes with micronuclei were highly correlated with age and smoking habit in control group. But, in chromate exposed group, age and logarithmic converted concentration of urinary Cr were significantly correlated with appearance of micronuclei. In both of control and exposed group, age, urinary concentration of Cr and logarithmic converted concentration of blood Cr were thought to be important variables. Conclusions: There was close relationship between the micronuclei assay for evaluation of mutagenesis and biological exposure markers such as blood or urinary Cr concentration of chromate workers. And obtained results suggested that further studies for establishing age-related reference frequencies of the micronuclei appearance for general people of Korean were needed to clarify physical increment with aging.
나수균,정호원,최창욱 대한스포츠의학회 1996 대한스포츠의학회지 Vol.14 No.1
Osteochondritis dissecans of the capitellum is a condition in which segment of articular cartilage with its underlying subechondral bone gradually separates from the surrounding osteocartilaginous tissue. If there is no loose body, conservative management can be done but operative treatment is indicated when consevative treatment is failed or loose bodies causes symptoms. We operated 12 cases of ostechondritis dissecans of the elbow who were followed for the average of 2 years 3 months postoperatively, at the Department of Orthopedic Surgery, College of Medicine, Soonchyang University, Hosptial from January, 1989 to September 1994. The Results were follow as. 1. Twelve cases between the age of 13 and 22 years(mean 17.3) were seen with chronic stress injuries of the elbow resulting from sports activity. 2. Clinical pictures were pain(100%), reduced range of motion(83%), locking(50%), and click sound(17%). 3. Treatment was performed by mutiple drilling in 5 cases, removal of loose body in 4 cases, removal of loose body and curettage in 2 cases and removal of loose body and multiple drilling in 1 case. 4. According to Smillie evaluation, Results were excellent in 5 cases(42%), good in 5 cases(42%), and moderate in 2 cases(16%). 5. All of excellent results returned to the pre-injury level of sports activity at the time of follow up.