류마티스성 관절염 및 퇴행성 골관절염에 있어서의 Tenoxicam(Tilcotil^(�))제제의 임상적 연구

이준규,임현수,이정웅,김석범 최신의학사 1988 最新醫學 Vol.31 No.6

슬개골 골절의 임상적 고찰

이준규,안상로,박찬희 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

We studies the cases of 30 patients who had fracture of patella, 28 patients were male and 2 patients were female. We treated the patients with operative treatment in 27 patients and with nonoperative treatment in 3 patients. The results are as follows. 1. It was more frequent in male, and average age of patient was 38.5 years old. 2. Most frequent cause of fractures was traffic accident. 3. Open fracture was 76.7%, and transverse or bursting fracture was 66.7%. 4. The end result was dependent on the initial trauma. 5. The associated injuries were frequent nearby the knee joints.

퇴행성 골관절염에 있어서 Diacerhein(Artrodar^(�)) 제제의 효과에 대한 임상적 연구 : Prioxicam 제제 투여군과의 비교연구

이준규,신현대,이정구 최신의학사 1990 最新醫學 Vol.33 No.2

척추관 협착증에 대한 연구 : 요추관 협착증 환자에서 협착 부위에 따른 수술적 치료의 결과 Results of the Operative Treatments by the Level of Lumbar Spinal Stenosis

이준규,안재성,양준영 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Spinal stenosis is any type of narrowing of the main spinal canal, nerve canal or foramina from structural abnormality of bony components. Posterior decompression only provide relief of pain and restoration of neurologic function, and simultaneous posterolateral fusion is needed for prevention of spinal instability after wide posterior decompression. The degree of decompression (focal or wide), instrumentation and bone graft is dependent to the level of stenosis and instability. The purpose of this study is to compare the operative results clinically and radiologically by the level of spinal stenosis. We reviewed 73 patients of lumbar spinal stenosis who had undergone operations with posterior decompression or posterolateral fusion with spinal instrumentation at our hospital, From January 1987 to October 1997. We classified the level of stenosis into one level, two level and multi-level(above three level) stenosis, and on the last follow up, radiological bony union, clinical results, and complications were compared. The following results were obtained. I. The one level was 42 cases(57.6%), two level 24 cases(32.9%), and multi-level stenosis 7 cases(9.6%) and the most common stenotic level was at LA-5, 31 cases(42.5%). 2. Posterior decompression only were carried out on 20 patients(27.4%), and simultaneous posterolateral fusion with instrumentation were 53 patients(72.6%), CD 4 cases, CCD 11 cases, PWB 2 cases, and Diapason 36 cases. 3. The radiologic union rate was 41 cases(97.6%) in one level, 22 cases(87.5%) in two level, 6cases(85.7%) in multi-level spinal stenosis. 4. The excellent or good clinical results(by the Kikaldy-Willis criteria) were 40 cases (95.2%) in one level, 22 cases(91.8%) in two level, 6 cases(85.7%) in multi-level spinal stenosis. 5. The postoperative complications such as infection, metal failure, neurologic deficit or death were 6 cases(14.3%) in one level, 4 cases(21%) in two level, 3 cases(44.3%) in multi-level stenosis.

백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

천추 골절에 대한 임상적 연구

이준규 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

Sacral fractures and lumbosacral dislocation are rare condition but almost constitute approximately 1% of all spinal fractures. They are frequently associated with pelvic fractures and often are overlooked. Lafollette, Levine, and McNiesh noted that 60% of sacral fractures are missed initially. So simple plain radiology are not sufficient for diagnose sacral fractures. Recently advanced diagnostic immaging technique, ie computerized tomogram, has more accate diagosis of sacral fractures. A high index of suspicioun is necessary to diagnose sacral fractures in patients with multiple trauma. The most common causes of this fractures are motor vehicle accidents and falls. Neural and nerve roots damage frequently noted in sacral fractures and lumbosacral dislocation because sacrum is continuation of the spine and contain of the neural tissue. The classification of sacral fractures are not well established until now, some authurs classified sacral fractures with corelation of neural damage, but it is not clear betwen fractures pattern and prognosis. The aimes of paper to evaluation of neural damage incidence, fracrures patterns, prognosis of the sacral fractures, So we studied 12 cases of sacral fractures retrospectively admmited to Dept' of orthpaedic surgery of Chungnam university hospital from 1987 to 1992 and mean follow up is 27 months. The results of this study are following. 1) Sacral fractures combined pelvic fracure always. 2) Simple plain X-ray missed sacral fractures frequently, so computerized tomogram is necessary at unstable pelvic fracture. 3) The sacral fractures are involved the neural canal and foramen commonly, but neural deficits are uncommon. 4) The overall prognosis of sacral fractures are followed by combined pelvic farctures. 5) The isolated sacral fractures are rare and the prognosis is good.

대퇴골 과상부 골절에 대한 연구 : 과간 골절을 중심으로 Focus on Intercondylar Fractures

이준규,임상덕 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

Supracondylar and intercondylar fractures of the femur remain difficult fracture to treat successfully, because of specific anatomical structure and location. There was a controversial in method of treatment, classification, and clinical result. Any mode of classification in intercondylar fracture, which reflects profound relationship of clinical aspects, has not been presented yet. So, a new classification system for fracture of the intetcondylar fracture of the distal femur are presented and clinical results are analyzed, according to type of fracture. The result are as follows: 1. The prevalent age was 3rd and 4th decade, and the sex ratio between males and females was 3.5:1. The mean age was 37.3 years old. 2. The satisfactory result of surgical treatment was 56.3% and conservative treatment was 33.3% respectively. 3. The intercondylar fracture of the distal femur were classified into 4 types, based on state of cortical comminution and involvement of joint surface. Type A (simple intercondylar fracture): there was no or slight comminution. Type B(lateral comminuted intercondylar fracture): there was comminution on lateral side of supracondylar or condylar cortex. Type C (medial comminuted intercondylar fracture) :

불안정성 골반골절의 수술적 치료

이준규,류천환 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

Massive pelvic disruption is an important and aften life threatening injury. The goals of orthopedic management of pelvic bone injuries are mobilization of parient as early as possible by achieving anatomical reduction and secure fixation of fragments. The authers reviewed 26 cases of unstable pelvic bone fracture treated at the orthopedic department of Chung Nam National University Hospital during the period from January 1985 to August 1990. The injury was classified according to the Pennal and Bucholz method and analyzed the causes of injury, methods of treatment. The results were obtained as follows. 1. The highest incidence was in the 3rd decade and sex ratio between male and female was 6:7. 2. The causes of injury were traffic accidents, fall down, motor bicycle accidents, industrial accidents in order of frequency. 3. According to classification of Pennal et al, type II fracture due to lateral compression injury was most common(68%). According to classification of Bucholz, type II fracture was most common(77%). 4. The fracture of tibia or fibular was most commonly associated bone injury and the most common associated soft tissue injury was genitounary tract injury. 5. 10 cases of Bucholz type II were treated with external fixation with internal fixation or internal fixation. 6 cases of Bucholz type III were treated external fixation or external fixation with internal fixation or internal fixation. 6. The result analysed by grading the outcome of pelvic fracture proposed SAID ABDUL MAJEED were excellant, good, fair, poor; 4, 6, 4, 0, in operative cases, 0, 3, 3, 4 in conservative cases. 7. The average weeks of immobilization were 6 in operative cases, 12 in conservative cases. 8. Even unstable pelvic bone fracture, we recommend early anatomical reduction and secure fixation with operative management.

편측하지의 대퇴골 및 경골골절에 대한 임상적 고찰

이준규,김석범 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

The fracture of the ipsilateral femur and tibia is ususlly produced by violent external forces. It has many problems in the treatment, and may produce many complications. There are no many literatures about the method of treatment, and it may produce variable prognosis with different treatment. The most important objectives of the treatment is the restoration of the function. It can be obtained by early exercise therough the rigid fixation of the both fractures. The authors reviewed 18 cases of fracture of the ,ipsilateral femur and tibia treated at the department of orthopaedic surgery CNUH. and compared the results according to the method of treatment. The results were as follows: 1. Fifteen patients were male, and three patients were female. Of the eighteen patients, eleven patients were at their third and fourth decades. 2. The causes of the injury were traffic accident in fifteen cases, and industrial injuries in three cases. 3. The femoral fractures were open in five cases, and in twelve cases of the tibial fractures. 4. The femur fractures wer treated by internal fixation in sixteen cases, and by conservative treatmentin two cases. 5 The tibial fractures were treated by internal fixation in eight cases, by external fixtion in eight cases, and by conservative treatment in two case. 6. After follow up, the restoration of the function was maximum in the group of femoral internal fixation and tibial internal fixation, and the restoration of the function was minimum in the group of conservative treatment of the femur fractures. 7. The most important point of the treatment was early exercise through the rigid fixatioo of the both fractures.

보존적 치료 및 수술적 치료에 의한 상위 경추 골절 및 탈구의 안정성

이준규,안재성,양준영,이장익 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

In general, hangman's fracture, odontoid Type III fractures, and most miscellaneous axis fractures are effectively managed with nonoperative methods (typically, the halo vest with its rigid external immobilization). Halo apparatus is a reliable instrument for the management of cervical spine injury, including that of odontoid fractures and other C1-2 injuries. Surgical fusion is the usual alternative to the halo device. Posterior wiring with or without fusion using autogenous iliac bone graft is probably the most common surgical treatment of cervical spine fracture and dislocation. The purpose of this study was to compare with stability of each others and to estimate the atlanto-dental interval and space for available in patients who were received conservative treatment and operative treatment due to upper cervical spine fracture and/or dislocation. 25 patients who were recieved conservative and operative management due to fracture and/or dislocation of the upper cervical spine (Cl and C2) during 1990. Jan. to 1997. May. were defined as a patient group. 12 patients were received conservative treatment. 13 patients were received operative treatment. In patient group who were received conservative treatment, the average of ADI and SAC was within normal range. In patient group who were received operative treatment, the average of ADI and SAC was within normal range. The patient group with the ADI and SAC of normal range were stable with good bone union at the last follow-up examination. Also the patient group was received fusion as their initial treatment for injuries incurred 1 month to 8 month prior to hospitalization were stable with good bone union.