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Park, Juhun,Lim, Jong Hyun,Jin, Hye Jun,Namgung, Seon,Lee, Sang Hun,Park, Tai Hyun,Hong, Seunghun The Royal Society of Chemistry 2012 The Analyst Vol.137 No.14
<P>We developed an olfactory-nanovesicle-fused carbon-nanotube-transistor biosensor (OCB) that mimics the responses of a canine nose for the sensitive and selective detection of hexanal, an indicator of the oxidation of food. OCBs allowed us to detect hexanal down to 1 fM concentration in real-time. Significantly, we demonstrated the detection of hexanal with an excellent selectivity capable of discriminating hexanal from analogous compounds such as pentanal, heptanal, and octanal. Furthermore, we successfully detected hexanal in spoiled milk without any pretreatment processes. Considering these results, our sensor platform should offer a new method for the assessment of food quality and contribute to the development of portable sensing devices.</P> <P>Graphic Abstract</P><P>We developed an olfactory-nanovesicle-fused carbon-nanotube-transistor biosensor (OCB) that mimics the responses of a canine nose for the sensitive and selective detection of hexanal, an indicator of the oxidation of food. OCB devices have been utilized to evaluate spoiled milk without any pretreatment. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2an16274a'> </P>
Park, Sung Young,Choi, Dong Shin,Jin, Hye Jun,Park, Juhun,Byun, Kyung-Eun,Lee, Ki-Bum,Hong, Seunghun American Chemical Society 2011 ACS NANO Vol.5 No.6
<P>We report a method for selective growth and structural-polarization-controlled neuronal differentiation of human neural stem cells (hNSCs) into neurons using carbon nanotube network patterns. The CNT patterns provide synergistic cues for the differentiation of hNSCs in physiological solution and an optimal nanotopography at the same time with good biocompatibility. We demonstrated a polarization-controlled neuronal differentiation at the level of individual NSCs. This result should provide a stable and versatile platform for controlling the hNSC growth because CNT patterns are known to be stable in time unlike commonly used organic molecular patterns.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2011/ancac3.2011.5.issue-6/nn2006128/production/images/medium/nn-2011-006128_0004.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn2006128'>ACS Electronic Supporting Info</A></P>
미립화 및 분무장치 1 : 노즐 홀 출구 형상과 감압비등 현상이 직분식 다공 가솔린 인젝터의 노즐 출구 적심에 미치는 영향
박찬수 ( Chansoo Park ),박상재 ( Sangjae Park ),오희창 ( Heechang Oh ),이주헌 ( Juhun Lee ),배충식 ( Choongsik Bae ) 한국액체미립화학회 2015 한국액체미립화학회 학술강연회 논문집 Vol.2015 No.-
Nowadays, direct fuel injection into the engine cylinder technologies are becoming standard fuel injection regime in spark ignition engines. Unlike conventional port fuel injection (PFI) engines, Particulate matter (PM) emission from the direct injection spark ignition (DISI) engines is an important issue in the automotive industry due to stringent emission regulations. Fuel wetting on the surface of the injector nozzle tip has been pointed out as a major source of PM emission and injector tip fouling in the DISI engines. In the present study, the degree of gasoline fuel wetting on the surface of nozzle tip was evaluated, and the mechanism of injector tip wetting was explored. To measure the quantity of the wetted fuel, laser induced fluorescence (LIF) imaging technique was used. Fourth harmonic wavelength (266 nm) high intensity laser light from Nd:Yag laser was used as an excitation source. Emitted light from the wetted fuel was filtered by a bandpass filter (300-430 nm) and captured by intensified charge coupled device (ICCD) with a long distance microscope. Ambient conditions are adjusted to gasoline fuel injection timing of real engine operating conditions under different engine load, and experiment was performed in a constant volume chamber. From the result, a conventional step-hole shaped nozzle showed less fuel wetting than that of diverging shaped nozzle hole, and fuel wetting reduction potential of converging shaped concept can be expected even though it was hard to compare the results of the converging concept to the other concept. Fuel wetting under flash boiling conditions were higher than that under non-flash boiling conditions. In order to explore the mechanism of fuel wetting on the surface of the injection nozzle tip, back light illuminated spray imaging technique was utilized. The fuel wetting mechanism could be analyze through the transient fuel injection phenomenon including opening and closing events. Especially, it is thought that fuel wetting of wide near nozzle spray angle at the start of injection (SOI), transient spray angle fluctuation during the injection and low momentum liquid ligaments as well as droplets are main reasons of injector nozzle tip wetting.
Park, Youngmin,Xu, Zheng-Yi,Kim, Soo Youn,Lee, Jihyeong,Choi, Bongsoo,Lee, Juhun,Kim, Hyeran,Sim, Hee-Jung,Hwang, Inhwan Americ 2016 The Plant cell Vol.28 No.10
<P>The phytohormone abscisic acid (ABA) plays crucial roles in various physiological processes, including responses to abiotic stresses, in plants. Recently, multiple ABA transporters were identified. The loss-of-function and gain-of-function mutants of these transporters show altered ABA sensitivity and stomata regulation, highlighting the importance of ABA transporters in ABA-mediated processes. However, how the activity of these transporters is regulated remains elusive. Here, we show that spatial regulation of ATP BINDING CASETTE G25 (ABCG25), an ABA exporter, is an important mechanism controlling its activity. ABCG25, as a soluble green fluorescent protein (sGFP) fusion, was subject to posttranslational regulation via clathrin-dependent and adaptor protein complex-2-dependent endocytosis followed by trafficking to the vacuole. The levels of sGFP: ABCG25 at the plasma membrane (PM) were regulated by abiotic stresses and exogenously applied ABA; PM-localized sGFP: ABCG25 decreased under abiotic stress conditions via activation of endocytosis in an ABA-independent manner, but increased upon application of exogenous ABA via activation of recycling from early endosomes in an ABA-dependent manner. Based on these findings, we propose that the spatial regulation of ABCG25 is an important component of the mechanism by which plants fine-tune cellular ABA levels according to cellular and environmental conditions.</P>
CMOS 아날로그 전류모드 곱셈기의 선형성과 동적범위 향상을 위한 회로설계 기법에 관한 연구
Daniel Juhun Lee,김형민(Hyung-Min Kim),박소연(So-Youn Park),노태민(Tae-Min Nho),김성권(Seong-Kweon Kim) 한국전자통신학회 2020 한국전자통신학회 논문지 Vol.15 No.3
이 논문에서는 아날로그 전류모드 인공지능 프로세서에서 핵심 디바이스 중에 하나인 아날로그 전류 모드곱셈기 회로의 선형성과 동적범위 향상을 위한 설계 기법을 소개한다. 제안하는 회로는 4 quadrant Translinear loop를 NMOS 트랜지스터만으로 구성하여, 트랜지스터의 물리적 Mismatch를 최소화하는 설계로 0.35𝜇𝑚 CMOS 공정에서 117𝜇𝑚 x 109𝜇𝑚로 구현가능하였으며, 최대 전고조파왜율 0.3% 의 선형성을 확보할 수 있었다. 제안한 아날로그 전류모드 곱셈기는 전류모드 인공지능 프로세서의 핵심 회로로 유용할 것으로 기대된다. In this paper, we present a design method for improving the linearity and dynamic range of the analog current mode multiplier circuit, which is one of the key devices in an analog current mode AI processor. The proposed circuit consists of 4 quadrant translinear loops made up of NMOS transistors only, which minimizes physical mismatches of the transistors. The proposed circuit can be implemented at 117𝜇𝑚 x 109𝜇𝑚 in 0.35𝜇𝑚 CMOS process and has a total harmonic distortion of 0.3%. The proposed analog current mode multiplier is expected to be useful as the core circuit of a current mode AI processor.
Injector tip wetting visualization under flash-boiling and non-flash boiling conditions
( Chansoo Park ),( Jinyoung Jung ),( Choongsik Bae ),( Heechang Oh ),( Juhun Lee ) 한국액체미립화학회 2017 한국액체미립화학회 학술강연회 논문집 Vol.2017 No.-
In spite of various research on the particulate matter emission reduction for the direct injection spark ignition engine, particulate number (PN) emission is still an unsolved challenge in automotive society. Among various reasons of PN emission, injector tip wetting by residual fuel after fuel injection is one of emerging issue because it is a main source of diffusion bum and injector tip fouling. In this study, mechanism of injector tip wetting under flash boiling and non-flash boiling condition was studied. In order to measure the quantity of wetted fuel on the surface of fuel injector, laser induced fluorescence (LIF) technique was used. The fluorescence signal was captured by an intensified CCD camera with long distance microscope. The excitation light source was 266 nm wave length Nd:YAG laser. Direct Mie-scattering image of injector step-hole and backlight image of near-hole spray were used to explain the mechanism of the phenomenon. For further study, the effect of injector nozzle outlet configuration on the injector tip wetting was explored with various fuel injectors which have various nozzle outlet configuration. In the result, step-hole showed negative effect on injector tip wetting. Especially, for the larger diameter step-hole case showed larger tip wetting area. Flash boiling conditions showed larger injector tip wetted area compared to that of non-flash boiling conditions. It was thought that higher near-nozzle spray angle was the reason of larger injector tip wetted area due to increased interaction of spray and step-hole outlet.