Electrophoretic Superconducting Film Applications

( Feng Hua Li ),( Jue Wang ),( Dea Wha Soh ),( Zhang Guo Fan ) 한국동굴학회 2006 동굴 Vol.76 No.-

YBa2Cu3O7-6 superconductor films have been prepared on silver substrates by electrophoretic deposition. As silver does not react with YBa2Cu3O7-6 compound and has little influence on its superconductivity, it is usually doped in YBa2Cu3O7 to improve the strength of the material and eliminate micro cracks. It has been proved that Ag additive can lower the melting temperature of YBa2Cu3O7-6 and act as linking bridge among YBa2Cu3O7-6 particles, thus in this paper Ag doped YBa2Cu3O7-6 thick films are prepared by electrophoretic co deposition. As there are only some referenced experience formula and models for co electrophoretic deposition and does not exist unified explanation, the behavior of Ag particles during co electrophoretic deposition is also studied.

MUTYH Association with Esophageal Adenocarcinoma in a Han Chinese Population

Kong, Feng,Han, Xue-Ying,Luan, Yun,Qi, Tong-Gang,Sun, Chao,Wang, Jue,Hou, Hua-Ying,Jiang, Yu-Hua,Zhao, Jing-Jie,Cheng, Guang-Hui Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Adenocarcinoma of esophagus (AE) is a complex disease, affected by a variety of genetic and environmental factors. Much evidence has shown that the MutY glycosylase homologue (MUTYH) plays a key role in the pathogenesis of many cancers. However, there have been no reports on influence on AE in the Han Chinese population. The objective of this study was to investigate this issue. A gene-based association study was conducted using three single nucleotide polymorphisms(SNPs) reported in previous studies. The three SNPs (rs3219463, rs3219472, rs3219489) were genotyped in 207 unrelated AE patients and 249 healthy controls in a case-control study using polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP). The results revealed that the genotype distribution of rs3219472 differed between the case and control groups (OR=1.66,95%CI=1.11-2.48, P=0.012), indicating that an association may exist between MUTYH and AE. These findings support a signifcant role for MUTYH in AE pathogenesis in the Han Chinese population.

Research on Improved Hadoop Distributed File System in Cloud Rendering

Ren Qin,Gao Jue,Gao Honghao,Bian Minjie,Xu Huahu,Feng Weibing 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.11

With the rapid development of cloud computing technology, it’s the cloud rendering that cloud computing is applied to render the job in CG (Computer Graphic) industry. The cloud rendering can handle a large number of rendering requests which are enormous pressure for back-end servers in system. Facing with massive data and computing resources, the bottleneck of original HDFS (Hadoop Distributed File System) based on cloud computing has become more and more prominent, such as the failure of single Namenode, scalability issues. Therefore, the paper proposed an improved HDFS which evolved a single Namenode into multi-Namenode. In HDFS, Metadata management is very important. So this paper presented a two-level Metadata distribution algorithm. The two-level algorithm was based on the principle that different distribution strategies were used to different categories of Metadata. The experiments verified that the improved HDFS effectively improved the performance of the system.

3.2-kW 9.7-GHz Polarization-maintaining Narrow-linewidth All-fiber Amplifier

Hang Liu,Yujun Feng,Xiaobo Yang,Yao Wang,Hongming Yu,Jue Wang,Wanjing Peng,Yanshan Wang,Yinhong Sun,Yi Ma,Qingsong Gao,Chun Tang 한국광학회 2024 Current Optics and Photonics Vol.8 No.1

We present a Yb-doped narrow-linewidth polarization-maintaining (PM) all-fiber amplifier that achieves a high mode-instability (MI) threshold, high output power, and 9.7-GHz spectral linewidth. Six wavelength-multiplexed laser diodes are used to pump this amplifier. First, we construct a high-power fiber amplifier based on a master oscillator-power amplifier (MOPA) configuration for experiments. Subsequently, we examine the MI threshold by individually pumping the amplifier with wavelengths of 976, 974, 981, 974, and 981 nm respectively. The experimental results demonstrate that the amplifier exhibits a high MI threshold (>3.5 kW) when pumped with a combination of wavelengths at 974 and 981 nm. Afterward, we inject an optimized phase-modulated seed with a nearly flat-top spectrum into this amplifier. Ultimately, laser output of 3.2 kW and 9.7 GHz are obtained.

Comparison of the Efficacy and Safety of EFGR Tyrosine Kinase Inhibitor Monotherapy with Standard Second-line Chemotherapy in Previously Treated Advanced Non-small-cell Lung Cancer: a Systematic Review and Meta-analysis

Qi, Wei-Xiang,Shen, Zan,Lin, Feng,Sun, Yuan-Jue,Min, Da-Liu,Tang, Li-Na,He, Ai-Na,Yao, Yang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

Purpose: To compare the efficacy and safety of epidermal growth factor receptor tyrosine kinase inhibitormonotherapy (EFGR-TKIs: gefitinib or erlotinib) with standard second-line chemotherapy (single agent docetaxel or pemetrexed) in previously treated advanced non-small-cell lung cancer (NSCLC). Methods: We systematically searched for randomized clinical trials that compared EGFR-TKI monotherapy with standard second-line chemotherapy in previously treated advanced NSCLC. The end points were overall survival (OS), progression-free survival (PFS), overall response rate (ORR), 1-year survival rate (1-year SR) and grade 3 or 4 toxicities. The pooled hazard ratio (HR) or risk ratio (RR), with their corresponding 95% confidence intervals (CI) were calculated employing fixed- or random-effects models depending on the heterogeneity of the included trials. Results: Eight randomized controlled trials (totally 3218 patients) were eligible. Our meta-analysis results showed that EGFR-TKIs were comparable to standard second-line chemotherapy for advanced NSCLC in terms of overall survival (HR 1.00, 95%CI 0.92-1.10; p=0.943), progression-free survival (HR 0.90, 95%CI 0.75-1.08, P=0.258) and 1-year-survival rate (RR 0.97, 95%CI 0.87-1.08, P=0.619), and the overall response rate was higher in patients who receiving EGFR-TKIs(RR 1.50, 95%CI 1.22-1.83, P=0.000). Sub-group analysis demonstrated that EGFR-TKI monotherapy significantly improved PFS (HR 0.73, 95%CI: 0.55-0.97, p=0.03) and ORR (RR 1.96, 95%CI: 1.46-2.63, p=0.000) in East Asian patients, but it did not translate into increase in OS and 1-year SR. Furthermore, there were fewer incidences of grade 3 or 4 neutropenia, febrile neutropenia and neutrotoxicity in EGFR-TKI monotherapy group, excluding grade 3 or 4 rash. Conclusion: Both interventions had comparable efficacy as second-line treatments for patients with advanced NSCLC, and EGFR-TKI monotherapy was associated with less toxicity and better tolerability. Moreover, our data also demonstrated that EGFR-TKImonotherapy tended to be more effective in East Asian patients in terms of PFS and ORR compared with standard second-line chemotherapy. These results should help inform decisions about patient management and design of future trials.

Effects of SRBSDV-infected rice plants on the fitness of vector and non-vector rice planthoppers

Hong-Xing Xu,Hong-Xing Xu,Xu-Song Zheng,Yajun Yang,Jue-Feng Zhang Zhang,Zhong-Xian Lu 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.3

Southern rice black-streaked dwarf virus (SRBSDV) is a new member of the genus Fijivirus and transmitted by whitebacked planthopper (WBPH), Sogatella furcifera (Horváth). The rice area affected by SRBSDV and the subsequent damages are increasing rapidly. In current study, we evaluated the effects of SRBSDV-infected plants on the ecological fitness and the tolerance to adverse environmental factors of vector WBPH and non-vector brown planthopper (BPH), Nilaparvata lugens (Stål). Our study revealed that the fitness of WBPH and BPH were both influenced by feeding on SRBSDV-infected rice. Fecundity ofWBPH feeding on the SRBSDV-infected rice plants were higher than those on healthy plants, nymphal duration of male WBPH prolonged markedly by 0.77 d (P b 0.05), while the weight of brachypterous female adults significantly decreased (P b 0.05), and the average survival time shortened both at 26 °C and 31 °C, respectively. Median lethal time of WBPH on SRBSDV-infected and healthy rice plants were 80 h and 112 h at 26 °C, 64 h and 88 h at 31 °C, respectively. As for non-vector BPH, nymph survival rate decreased significantly by 11.22% (P b 0.05) and the longevity of female adults also shortened (P b 0.05), while hatchability of BPH eggs increased (P b 0.05). Survival time of BPH feeding on healthy rice at 26 °Cwas significant longer than those feeding on healthy and infected rice at 31 °C. The above results imply that the vectorWBPH suffers much stronger effects than non-vector BPH fromfeeding on SRBSDVinfected rice plants.

High Expression of MICA in Human Kidney Cancer Tissue and Renal Cell Carcinoma Lines

Jia, Hong-Ying,Liu, Jun-Li,Zhou, Cheng-Jun,Kong, Feng,Yuan, Ming-Zhen,Sun, Wen-Dong,Wang, Jue,Liu, Ling,Zhao, Jing-Jie,Luan, Yun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

The overall incidence and mortality of renal cell carcinoma (RCC), the most common kidney cancer, are steadily increasing for reasons that are not fully explained. Our aim was to explore the expression of membrane MHC class I chain-related gene A (mMICA) in human RCC cell lines and tissue specimens, and to determine expression of soluble MICA (sMICA) in serum of patients with renal cell carcinoma, we used flow cytometry (FCM) and immunohistochemistry as well as an enzyme linked immunosorbent assay (ELISA). The results showed that percentage of mMICA expression was significantly increased in human kidney cancer tissues and RCC cell lines (786-O and Ketr-3) than that in healthy adults and human embryonic kidney 293 (HEK293) cell line individuality (P<0.05). sMICA content in healthy adults was negative, but in renal cancer patients was significantly elevated (P<0.05). Our research showed that high expression of MICA in human kidney cancer, this results show that MICA might serve as potential tumor-associated antigen (TAA) in RCC.

Dynamics of Yeast-like Symbiote and its Relationship with the Virulence of Brown Planthopper, Nilaparvata lugens Stal, to Resistant Rice Varieties

Zhong-Xian Lu,Xiao-Ping Yu,Jian-Ming Chen,Xu-Song Zheng,Hong-Xing Xu,Jue-Feng Zhang Zhang,Lie-Zhong Chen 한국응용곤충학회 2004 Journal of Asia-Pacific Entomology Vol.7 No.3

Abundance of the yeast-like symbiote (YLS) in brown planthopper (BPH), Nilaparvata lugens Stl, collected from rice fields in China and obtained from International Rice Research Institute (IRRI), was monitored. The role of YLS in nymph survival rate, development and adult reproduction, and activities of transaminases in BPH on different resistant rice varieties were examined. Also, the relationship between YLS and virulence shifts of BPH to resistant rice varieties was discussed. The results indicated that the virulence of BPH populations to resistant rice varieties was strongly related to the abundance of YLS in 5th instar nymphs and brachypterous females of BPH field populations at Nanning in South China and Hangzhou in East China, showing the more abundance of YLS in BPH, the higher virulence of BPH to resistant rice varieties, while no obvious differences in YLS abundance were monitored between three BPH biotypes. Numbers of YLS reduced significantly in female adult of BPH biotype 1 fed on resistant rice varieties IR26, Mudgo and ASD7, compared with that fed on susceptible rice variety TN1. The lowest YLS abundance of BPH from field population was found in 2nd generation successively fed on resistant varieties, and the number of YLS was resumed at 4th generation when the BPH has adapted the resistant varieties. The markedly lower nymphal survival rate, adult fecundity and activities of alanine and aspartic transminase, and significantly longer nymph duration in the three aposymbiotic biotypes than in the symbiotic ones were recorded on both susceptible and resistant rice varieties. However, the much greater differences between aposymbiotic and symbiotic BPH were found on the inadaptable resistant rice varieties than that on the fitness resistant rice varieties. Those results implied that YLS in BPH should play a crucial role in the virulent shift of BPH populations to resistant rice varieties.

Dynamics of Yeast-like Symbiote and Its Relationship with the Virulence of Brown Planthopper, Nilaparvata lugens Stal, to Resistant Rice Varieties

Lu, Zhong-Xian,Yu, Xiao-Ping,Chen, Jian-Ming,Zheng, Xu-Song,Xu, Hong-Xing,Zhang, Jue-Feng,Chen, Lie-Zhong Korean Society of Applied Entomology 2004 Journal of Asia-Pacific Entomology Vol.7 No.3

Abundance of the yeast-like symbiote (YLS) in brown planthopper (BPH), Nilaparvata lugens Stal, collected from rice fields in China and obtained from International Rice Research Institute (IRRI), was monitored. The role of YLS in nymph survival rate, development and adult reproduction, and activities of transaminases in BPH on different resistant rice varieties were examined. Also, the relationship between YLS and virulence shifts of BPH to resistant rice varieties was discussed. The results indicated that the virulence of BPH populations to resistant rice varieties was strongly related to the abundance of YLS in 5th instar nymphs and brachypterous females of BPH field populations at Nanning in South China and Hangzhou m East China, showing the more abundance of YLS in BPH, the higher virulence of BPH to resistant rice varieties, while no obvious differences in YLS abundance were monitored between three BPH biotypes. Numbers of YLS reduced significantly in female adult of BPH biotype 1 fed on resistant rice varieties IR26, Mudgo and ASD7, compared with that fed on susceptible rice variety TN1. The lowest YLS abundance of BPH from field population was found in 2nd generation successively fed on resistant varieties, and the number of YLS was resumed at 4th generation when the BPH has adapted the resistant varieties. The markedly lower nymphal survival rate, adult fecundity and activities of alanine and aspartic transminase, and significantly longer nymph duration in the three aposymbiotic biotypes than in the symbiotic ones were recorded on both susceptible and resistant rice varieties. However, the much greater differences between aposymbiotic and symbiotic BPH were found on the inadaptable resistant rice varieties than that on the fitness resistant rice varieties. Those results implied that YLS in BPH should playa crucial role in the virulent shift of BPH populations to resistant rice varieties.