생체분해성 안과제형의 안구내흡수정도와 안독성

민병무,김용백,박근성,송규상,양준묵,이성복,조항진,길숙종,김승영,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

An improved retinal tack can be used to fix the retina in complicated retinal detachment and proliferative vitreoretinopathy. We used the retinal tack made by biodegradable polyglycolic acid, polylactic acid and copolymers. The tacks with polyglycolic acid were placed in the retina the right eyes of 10 rabbits as group 1, with polylactic-polyglycolic acid copolymers as group 2 in each left eyes. We examined the absorption rates and degree of intraocular inflammation at 1 day, 1, 2, 4, and 8 weeks and compared both eyes. The tacks were absorbed with time in both eyes, but more rapid in copolymers. And there was no inflammation in both eyes. Now, this study will be a base on the drug delivery system in intraocular pharmacological and surgical management.

요인분석법을 이용한 광촉매 산화반응조의 최적 운영인자 도출

허준무,전승렬,이인형,김종수 한국환경농학회 2004 한국환경농학회지 Vol.23 No.2

폐수내의 오염물질 제거를 위해 광촉매 산화반응조의 운영인자로 선택한 대상물질의 초기농도, 자외선의 강도, 촉매의 표면적에 대해 실험을 수행하여 각 인자 수준에 따른 페놀농도의 제거율을 조사하고, 분산분석법을 통해 오차에 의한 영향을 평가하고, 요인분석법을 적용하여 각 인자 및 인자 사이의 상호작용 효과를 계산하여 광촉매 산화반응조의 최적운영 조건을 도출하였다. 광촉매 산화반응조의 실험인자로 선택한 페놀의 초기농도, 자외선의 강도, 촉매의 표면적이 페놀의 제거량에 미치는 정도를 조사하기 위하여 각 인자의 수준을 3가지로 변화시키고 반복횟수 3회인 예비실험을 통해, 각 인자의 수준변화가 페놀의 제거에 영향을 미칠 수 있다는 것을 분산분석법으로 검증하였으며, 시간당 페놀 제거농도는 각 인자의 수준을 각각 50 mg/L, 20,000 μW/cm², 2,105 cm²때 가장 높았다. 광촉매 산화반응조의 실험인자로 선택한 페놀의 초기농도, 자외선의 강도, 촉매의 표면적이 각각 페놀의 제거에 미치는 영향과 인자와 인자 사이에 존재하는 상호작용의 영향을 규명하기 위하여 각 인자의 수준이 2가지이고 반복횟수가 3회인 요인분석 실험을 수행하였다. 페놀의 초기농도를 5에서 50 mg/L로, 자외선 강도를 5,000에서 20,000 μW/cm² 촉매의 표면적을 740에서 2,105 cm²증가시킴으로써 얻을 수 있는 페놀농도의 제거율은 각각 1.86 및 1.79와 2.10 mg/L·hr 이었으며, 인자와 인자 사이의 상호작용 효과는 페놀의 초기농도와 촉매의 표면적 사이에 존재하는 상호작용의 영향을 제외 하고는 각 인자들의 주 효과에 비교하여 페놀의 제거농도에 미치는 영향이 상대적으로 적었다. 따라서 각 인자의 수준을 높은 방향으로 운영하는 것이 가장 많은 대상물질을 제거할 수 있지만 광촉매 산화반응조로 유입되는 오염물질의 농도를 조절하기 곤란하고, 자외선의 강도 증가 또한 전력비등으로 한계가 예견되므로, 대상물질의 제거에 가장 큰 영향을 미치는 촉매의 표면적을 증가시키는 것이 광촉매 산화 반응조를 효율적으로 운영하는 방안이라고 판단된다. The objective of this study is to determine the optimum conditions of operational parameters using factorial design for phenol degradation in photocatalytic oxidation reactors. Factorial design is widely used to select the dominant factors and their ranges in experiments involving several factors where it is necessary to study the effect of factors on a response. The effects of initial concentration of phenol, intensity of UV light and surface area of catalyst on phenol degradation were investigated. Two levels were considered in this study so that the experiment was a 2³ factorial design with three replicates. The experimental results show that an increase in initial concentration of phenol from 5 to 50 mg/L, intensity of UV light from 5,000 to 20,000 μW/cm² and surface area of catalyst from 740 to 2,105 cm² enhanced the phenol degradation rate by an average of 1.86, 1.79, and 2.10 mg/L·hr, respectively. Interaction effects do not appear to be as large on the phenol degradation rate as the main effects of single factors. The optimum working condition for photocatalytic oxidation reactors, despite the higher three factors the better removal rate, is the highest surface area of catalyst.

屋上綠化가 빗물流出量 및 水質에 미치는 影響

한무영,김준규,박상철 대한건축학회 2003 대한건축학회논문집 Vol.19 No.11

Greening roof is gaining much interest as means for reduction of heat island effect and prevention of urban flooding. However, the effect of Greening roof on the quantity and quality of runoff has not been addressed simultaneously. In this study, the characteristics of rainfall runoff is investigated by a set of pilot plants with different depths of soil in order to investigate the effect of greening roof on the runoff characteristics and runoff water quality. Greening roof had reduction of rainfall runoff about 23~95 % at the 10 cm of depth of soil and about 24~100% at the 20 cm of depth of soil. Also, greening roof could decrease runoff of rainfall about 84~91 % of total quantity of rainfall during experimental period. However, greening roof gives much impact to the water quality. Filtrate of greening roof has been neutralized (pH 7~7.5) from acidic (pH 4~5). However, electro conductivity and turbidity of greening roof slightly increased. Overall, the greening roof has a good potential to reduce and delay the runoff peak flow. The quality of runoff from greening roof is good enough to be used for non drinking purpose.

북제주 삼양화력발전소 주변해역의 식물플랑크톤 군집동태와 1차생산력

이준백,이무형,강동우 제주대학교 해양연구소 1998 해양자원연구소연구보고 Vol.22 No.-

프레스금형의 드로비드설계에 관한 실험적 연구

송준호,유호영,김진무 울산대학교 1994 공학연구논문집 Vol.25 No.2

정사각형 용기의 Deep Drawing 성형성 실험을 다양한 작업조건하에서 수행하였다. 본 연구에서는 재료의 유동상태와 판두께의 국부적 변화량을 성형성의 척도로 사용하였으며, Photo-etching 방법을 이용하여 이들을 측정하였다. Draw Bead의 크기, 블랭크 홀더력의 크기 및 윤활상태의 변화에 따른 정사각형 용기의 둘레방향, 대각선방향 및 반경방향으로의 판두께 변화량과 재료의 유동상태를 실험적으로 분석하였다. Experiments on the drawability of squared boxes have been performed under various working conditions. In the present work, the pattern of material flow and the local change in the thickness of shell are used as the measures of drawabilitiy and they are measured using the photo-etching technique. The size of draw bead, the magnitude of blank holding force and the condition of lubrication have been changed and their effects on the pattern of material flow and the thickness of shell along the circumferential, diagonal and radial directions of the squared boxes have been analyzed experimentally.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

세 건의 재해사고를 통한 우리 나라의 재해대책 분석

안무업,황성오,임경수,강성준 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Disaster is a any community or regional events that disrupts community functions and activities and cause concern for the lives, health, and property of the citizens of that community. Successful management of disaster requires adequate planning and practice drills. Emergency medical service must play an important role in disaster management because any disaster produces various types of patients who need emergent care. We tried to analyse korean disaster planning in review of three recent disasters including aircraft crash, ship submergence, and road traffic accident. The result of disaster survey shows that there are many defects in Korean disaster plan at the stage of notification, propagation, rescue, stabilization and withdrwal and emergency medical service system is not being involved in disaster management because korean disaster plan is a civil-defence model. We conclude that current korean disaster plan is inadequate for management of disaster and it should be reinforced.

코치들의 직업관 및 근무환경에 관한 조사 연구

차봉준,조재기,이무진 東亞大學校 附設 스포츠科學硏究所 1997 스포츠科學硏究論文集 Vol.15 No.-

This study aims at examining the factors of professional consciousness and working conditions of coaches which is an urgent question of Pusan athletics, and giving the basic data for the improvement of thier positions and working conditions, when international sports games such as the Asian Games in 2002, the East Asian Games in '97. The World Cup in 2002 of joint auspices of Korea and Japan are invited and it is filled with a great deal of interest of sports than ever before and Pusan in riging as an international sports city. The subjects of examination were limited to 138 coaches who worked at elementary school, middle school, high school in Pusan. The way of analysis of data was intersection analysis and significance also was proved using Χ2 and signicance level was 0.05. The reliance coefficient of questionnaire was 0.6819 relatively high culculating CronBacha alpha value. The results of this study are as follows ; in the first place, in the professional conciousness, the motivation to have chosen choach job was "have aptitude for" which was highest. All answered positively to the questions ; Do you think choach job is the task of life? Do you have your firm view of teaching in coach job. Do you think coach job should be suited to your character and aptitude. Can you find your life worth living as choach? Do you have self-esteem as a choach"; and the professional consciousness of choaches was very high. but the question to players that do you want to be a choach was answered negatively. Second, in the working conditions, the teaching time of a day was positive but compensation system such as salary, stability of job, and private time, vacation or day off, was negative and it was proved that choach job don't gain public acceptance. But the relationship with director were all positive. In the items that should be developed for working conditions, the most answers were "gurantee of job in his life". The mediums that should impreve these problems prositvely were "school", "Education Board", "athletics association" in order. In the reasion of being content with choach job, the most answers were "for finding his life worth living as a choach" but in the reason of being discontent with choach job, the most answers were "no guaranting of status and the unstability of job". The salary that choach receives now was "athletics association", "school", and "parents of students" and "Education Board" in order. As the result above, in the factor of professional consciousness answers were greatly high and positive, but in the factor of working conditions there still remained problems of status guarantee, salary, compensation system, and thhe unstability of job.

TCE의 분해를 위한 광촉매 산화반응조의 운전인자 도출에 관한 연구

허준무,전승렬,김종수 한국환경농학회 2003 한국환경농학회지 Vol.22 No.2

광촉매 산화반응으로 인한 난분해성 유기오염물질의 분해효율을 증가시키기 위하여 산화반응의 매개체인 TiO_2 광촉매의 새로운 제조방법을 개발하였고, 이를 이용하여 TCE의 효과적인 분해를 위한 광촉매 산화반응조의 최적 운영인자를 도출하였다 TiO_2 광촉매는 해교제(Davan-C 0.24 wt%)와 결합제(PVA 0.16 wt%)를 첨가하여 슬립 캐스팅 방법으로 제조하였다. 촉매의 특성 변화에 따른 실험결과로 TCE 수용액의 분해효율이 가장 좋은 촉매의 상태는 TiO_2 코팅 횟수가 1회이고 TiO_2 슬립의 두께가 1mm인 촉매로 확인 되었다. 촉매 사용시간에 따른 비교에서는 사용시간이 250 시간인 촉매가 새로이 제작하여 사용한 촉매의 TCE 분해효율보다 20% 정도 감소되었다. 광촉매 산화반응조의 물리적 운영인자 도출을 위한 실험결과로 산소의 전처리와 재순환을 실시하면 그렇지 않은 경우보다 TCE 분해효율이 증가되었다. 촉매의 단위 표면적당 수용액의 부피비가 1.47㎖/㎠ 이하에서 높은 TCE분해효율을 보였으며 UV 광량의 조절시 광량이 225 W/㎠×100에서 75.8%의 최대 TCE 분해효율을 보였다. TCE의 초기 ?逾돋?조절했을 경우에는 농도가 2 ㎎/L 이하인 경우에 TCE의 분해효율이 높았다. 따라서 본 연구에서 제시한 방법으로 제조한 촉매를 이용하여 적절한 UV 광량과 상기한 운영조건하에 광촉매 산화반응조를 운영한다면 정수 및 폐수에 함유된 난분해성 유기성 오염물질을 제거하기 위한 공정으로 활용될 수 있을 것으로 기대된다. The objectives of this study are to manufacture an efficient TiO₂ photocatalyst and to delineate optimum operational parameters for TCE (trichloroethylene) degradation in a photocatalytic oxidative reactor. The TiO₂ photocatalyst, irradiated by 365 nm UV Light, is expected to increase degradation of TCE in solution by a series of photocatalytic oxidations in the reactor. A new membrane TiO₂ photocatalyst was eventually developed by coating a mixture of Davan-C(0.24 wt%) and PVA(0.16 wt%) on the surface of slips using the slip-casting method. Results show that increase in the number of coating of TiO₂ sol on surface of photcatalysts and in the surface thickness improved the endurance and photocatalysts, but these physical modifications caused significant decrease in the overall degradation efficiency of TCE. Pre-aeration or recirculation of the influents to the reactors containing TCE increased degradation efficiency of TCE. The optimum operational conditions for the surface area of photocatalysts and UV light intensity appeared to be 1.47 mL/㎠ and 225 W/㎠×100, respectively, in the reactor. Based on the overall experimental results, the photocatalytic oxidation of TCE with the new membrane TiO₂ photocatalyst is found to be very effective under the operational conditions delineated in this study.

주택건설현장 폐 콘크리트 발생 저감 식스시그마 프로젝트 추진 사례 : a Six Sigma Project for Decreasing Waste Concrete in a Housing Construction Site

권혁무,김정택,최준호 한국품질경영학회 2000 품질혁신 Vol.1 No.1

본 사례는 국내 APT 건설 현장에서 수행된 식스시그마 프로젝트에 대한 것으로 페콘크리트 발생 저감 및 잔량발생에 영향을 미치는 주요 인자들을 파악하고 개선안을 도출하는 과정을 보였다. 프로젝트는 식스시그마의 방법론을 따라 정의, 측정, 분석, 개선, 관리의 절차에 따라 주요 변수를 규명하고 개선안을 찾아내는 식으로 진행되었다. 분석결과 페콘크리트 발생을 줄이기 위해서는 첫째, 거푸집 시공 및 타설 프로세스를 개선하고 둘째, 압송관 및 펌프카 내 잔여 레미콘을 최소한으로 감소시키며 셋째, 최종적으로 남은 레미콘을 재활용할 수 있도록 하는 세가지로 요약되었다.