가토 간의 VX2 carcinoma : 종양이식방법에 따른 영상소견의 차이 Different Radiologic Features According to Innoculation Methods

이준우,정진욱,최국명,김종재,김세형,최준일,이경호,김승협,박재형 대한초음파의학회 2000 ULTRASONOGRAPHY Vol.19 No.3

북제주 삼양화력발전소 주변해역의 식물플랑크톤 군집동태와 1차생산력

이준백,이무형,강동우 제주대학교 해양연구소 1998 해양자원연구소연구보고 Vol.22 No.-

Angelica gigas Nakai 成分의 藥理學的硏究

池亨浚 忠南大學校 1962 論文集 Vol.2 No.-

Two crystals were obtained from ether extract and saponificated Ether extract of root of Angelica gigas Nakai commonly called "TANG-GUI" in Korea. One crystal (m.p. 110-111℃) which was suggested as coumarine derivative was separated from ether extract of dried root. (Substance A) The other crystal (M.p. 178℃-180℃) which showed furo-coumarine reaction was separated from the saponificated ether extract. (Substance B) The general pharmacological effects of crystal (Substance A) and etherextract (Extract A) were studied and compared, and the following conclusions were obtained: LT50 of Subtance A is 382㎎/㎏., when given to mouse intraperitonially. Motility of excised intestine and uterus of rabbit was augmented by the treatment of Substance A, while Ertract A is inhibitory in same cocentration. Blood pressure of rabbit was elavated by Subtance A and A Extract Extract A stimulated the respiration of rabbit, but Substance A did not show any effect on respiration.

심실성 조기박동의 심전도학적 연구

배형준 서울保健大學 1995 論文集 Vol.15 No.1

A study on the ventricular premature beats was made on 123 cases diagnosed by surface electrocardiographic examination. The results were as follows : 1. Ventricular premature beats were observed in 123 cases of the 5,456 adult patients and the incidence of ventricular premature beats was 2.3%. 2. The ratio of male to female was 44.7% to 55.3%. The most frequent age group was 5th decade, and the incidence of ventricular premature beats rose suddenly over the 5th decade. 3. Atrial fibrillation was one of the most frequent arrhythmias associated with ventricular premature beats, being 24 cases(19.5%) Second most associating arrhythmias was bundle branch block with or without fascicular block, being 9 cases(7.3%). 4. Ventricular premature beats with interpolated beat were 8 cases(6.5%), with retrograde-P wave were 18 cases(14.6%), and end-diastolic ventricular premature beats were 8 cases(14.6 %). 5. 66 cases(53.7%) were classified as having ventricular premature beats originated in the right ventricle, 52 cases(42.3%) were originated in the left ventricle, and 5 cases(4.1%) had septal ventricular premature beats. 6. Ventricular bigeminy were 10 cases(8.1%), ventricular trigeminy were 4 cases(3.3%), and ventricular Quadrigeminy was 1 case(0.8%).

Y₂O₃함량에 따른 Al₂O₃- ZrO₂계 세라믹스의 특성

이형복,이홍림,홍기곤,김준태 연세대학교 산업기술연구소 1986 논문집 Vol.18 No.2

In this work the effect of Y₂O₃ content on Al₂O₃-ZrO₂ ceramics was studied and compared for coprecipitation and powder methods. Al₂O₃-ZrO₂ ceramics prepared by coprecipitation method showed the maximum M.O.R. value at 15 mole% ZrO₂ content for both 1.5 and 3 mole% Y₂O₃ addition, on the other hand, the ceramics prepared by powder method showed the increasing strength with increase of ZrO₂ content over the range of this work.

세라믹튜브 및 패킹형 플라스틱 여재충전 혐기성 여상의 유가공 폐수 처리특성 및 반응조 내부거동

허준무,장봉기,서성철,박종안,이종화,배형석,김준현 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2

This study was carried to develop of anaerobic reactor to be able to maximize the organic removal efficiency using laboratory-scale anaerobic filter. The ceramic tube and pall ring media were tested for the applicability as packing media of anaerobic filter for the treatment of a dairy waste. This study was conducted to determine the anaerobic treatability of a dairy waste, and investigate the effects of ceramic tube and pall ring media. Anaerobic filters were packed with packing volume of 65% of total working volume. When treating a dairy waste, the organic removal efficiency of anaerobic filter packed with pall rings was a little higher than that of anaerobic filter packed with ceramic tubes. This was because the reactor packed with ceramic tube had clogging problems and substrate transfer limitations. It seemed that the reactor packed with ceramic tubes had uneven packing due to structural characteristics. The COD removals of ceramic tube and pall ring anaerobic filters were greater than about 91% and 94%, respectively, at organic loading rate lower than 5kgCOD/㎥/d. The COD removals of both reactors decreased to 80% with organic loading rate of 10kgCOD/㎥/d. Biomass capture and solid-liquid-gas separation efficiency seemed to vary with the type of media.

핀의 최적 설계를 위한 구조화 표본추출 적용 연구

박홍준,김정호,전형주 순천대학교 2000 순천대학교 자연과학논문집 Vol.19 No.1

The Taguchi method by orthogonal array, one of the structured sampling methods, has many advantages which are row cost and time saving for experiments and researches. But this method has applied limited area especially about mechanical problems. So, we experimented whether the structured sampling is useful to apply optimal design of mechanical elements. First, we made a mechanical problem to determine optimal parameters of a pin with a hole. The second, we calculated combination of optimal parameters by simulation. At the same time, we seeked optimal combination by structured sampling using orthogonal array and ANOVA(Analysis of Variance). The last, we compared these two results. The experimental result have shown that the structured sampling method seeked optimal parameters exactly. So, we see some possibility in this application.

불안장애의 경계 : 강박장애와 정신분열병

임준석,김찬형 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6

Although obsessive-compulsive disorder (OCD) is recognized as a major psychiatric illness, few studies have investigated obsessive-compulsive symptoms in patients with schizophrenia. Recent increases in dual diagnosis due to changes to the DSM-IV diagnostic criteria, findings of obsessive-compulsive symptoms (OCS) after administration of atypical antipsychotics, in-creased reports of co-occurrence of schizophrenia and OCD have increased the interest in OCS in schizophrenia. The incidence of OCS patients with schizophrenia is reported to be 3-59% ; however, the rate of progression to schizophrenia from OCD is not higher than in the general population. Level of insight, which differentiates obsessions from delusions, can be confounded by the specifier 'with poor insight' in OCD. OCD with schizotypal personality disorder or poor insight differs from pure OCD in that it responds poorly to treatment, has a poor prognosis, leads to deficits in cognitive functioning similar to those observed in schizophrenia, and responds well to low-dose antipsychotics. In the past, it was believed that OCS could prevent or delay the deteriorative course of schizophrenia. However, recent studies have shown that co-occurrence of OCD and schizophrenia in-creases the severity of symptoms, delays the treatment response, and reduces socio-occupational functions. Schizophrenia and OCD share the same pathophysiology in that both diseases have defects in the fronto-basal functional circuitry of the brain. The use of serotonin and dopamine has been addressed in schizophrenia due to the use of atypical antipsychotics in patients with schizophrenia. The finding of drug-induced OCS suggested that the two diseases share a similar pathogenesis involving neurotransmitters. Further studies are needed to make an exact diagnosis between the two diseases and to determine the com-mon pathophysiology between OCD and schizophrenia.

PGE_2와 DBcAMP가 골조직 세포의 생리적 활성에 미치는 영향

이준기,채한정,강장숙,김형룡 원광대학교 생체재료·매식연구소 1998 원광생체재료·매식 Vol.7 No.2

One of the primary functions for which bones have evolved is to act as structural support. To achieve this goal, bones are remodeling throughout life so that their structure remains optimal for the prevailing mechanical environment. Bone remodeling consists of an initial phase of osteoclastic bone resorption followed by a bone formation period. Prostaglandins are potent regulators of bone formation and bone resorption that can have both stimulatory and inhibitory effects. Elevation of intracellular cAMP is an important intracellular signaling mechanism involved in the regulation of the expression of many proteins. In this study, the author examined whether PGE_2 or DBcAMP affected osteoblastic activation or osteoclastic differentiation in mouse bone marrow cells and osteosarcoma ROS 17/2.8 cells. The effect of PGE_2 and DBcAMP on the cell proliferation was measured by the incorporation of [^3H]-thymidine into DNA. From the result, PGE_2( 0.5-1 ㎍/ml ) and DBcAMP(0.1-0.5 mM) inhibited the [^3H]-thymidine incorporation into DNA. The effect of PGE_2 and DBcAMP on the induction of alkaline phosphatase(ALP) was investigated in ROS 17/2.8 cells cultured in medium containing 0.4% fetal bovine serum. PGE_2 and DBcAMP stimulated ALP activity in the cells. PGE_2 also increased the intracellular cAMPs contents with a maximal effect at 0.5 ㎍/ml. ROS 17/2.8 cells released nitric oxide upon stimulation of PGE2 or DBcAMP with interferon-γ. PGE_2 and DBcAMP increase the phosphorylation level of CREB(cAMP response element binding protein) without any change on the amount of CREB protein. Also, PGE_2 (10^-6 M) and DBcAMP (10^-4 M) significantly increase the generation of osteoclast-like cell in mouse bone marrow cell culture system. In conclusion, the results of this study suggested that PGE_2 and cAMP should appear to be an important regulatory molecule in the processes of bone formation and resorption.

병원내 생리기능 검사실의 적정 업무환경에 관한 연구

배형준,윤기은,김승곤,나동진,문희주,김태전,박정오 서울보건대학 1999 서울보건대학 부설 병원경영연구소 논문집 Vol.4 No.2

The purpose of this study was to suggest guideline for optimal work environment of physiological laboratory in hospital. Therefore this study was carried out to analyze the actual condition of laboratory system, major equipments and persons. The period of survey was from September to November 1997 and the objects were 123 laboratory. The major results of this study were as follows. 1. The optimal areas of general ECG room, exercise ECG room and echocardiology room were all 9-18㎡, that of Holter ECG room was 3-12㎡. The optimal areas of neurosystem laboratory were all 9-12㎡, those of respiratory system laboratory were all 9-18㎡. 2. The optimal number of persons laboratory of hospital 500 beds and less were 2∼3, those of 501∼700 beds were 3∼4.701∼1.000 beds were 4∼5 and over 1.001 beds were 7∼8 persons in circulatory system laboratory. The optimal number of persons laboratory of hospital 500 beds less than were 1∼2, those of 501∼700 beds were 3∼4, 701∼1.000 beds were 6∼7 and over 1.001 beds were over 8 persons in neurosystem laboratory. The optimal number of persons laboratory of hospital 500 beds and less 1. those 501∼1.000 beds were 1∼2 and over 1.001 beds were 2∼3 persons in repiratory system laboratory. 3. The optimal number of equipments of general ECG were 2∼3 in the 500∼1.000 beds hospital. there were 3∼4 units in the 1,001 beds. The optimal number of equipment EEG were both 1∼2 in the hospital 500 beds and less and 501∼700 beds. those were 4∼5 units in hospital over 701 beds. The optimal number of equipments of spirograph were both 1∼2 in the hospital 500 and less and 501∼1.000 beds. those were 2∼3 units in the over 1.001 beds. 4. In view of speciality and legal problem of physiofunctional test. we sugget that non-licensee were so quickly change place licensee in the interests of optimal work environment. 5. We suggest that to upgrade qualitative level of domestic equipment and to the more amplify utilization with respect to domestic equipment for the purpose of reducing loss of foreign money.