http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Jongseon Choi,So Yeon Kim 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.85 No.-
Nanocarriers have provided a new platform for the selective delivery of therapeutic agents into targetedcells and tissues using safe, efficient, and tractable routes. In particular, the integration of multipletherapeutic/diagnostic modalities into a single system has the great potential of enhancing theranosticefficiency against serious diseases with reduced side effects. In this study, a new light-triggeredtheranostic system using photosensitizer-conjugated gold nanorods (AuNR) with glutathione (GSH)-sensitive linkages was developed for cancer imaging and combinational phototherapy of photodynamictherapy (PDT) and photothermal therapy (PTT) to achieve a synergistic cancer treatment. AuNRs withvarious aspect ratios were prepared as photothermal agents, and then a folic acid (FA)-PEG blockcopolymer (FAP) and pheophorbide a (Pheo) were chemically conjugated to the surface of AuNRs foractive tumor targeting and PDT, respectively. The configuration of Pheo-conjugated AuNR nanocarriershas been precisely controlled through adjusting the feed composition ratio and the relationship betweenaspect ratio and absorption band of AuNRs. In particular, an AuNR with an aspect ratio of 3.84 andlongitudinal plasmon resonance at 873 nm (Pheo-conjugated AuNR100) exhibited superior performancein singlet oxygen generation, photothermal conversion effect, and GSH-mediated selective release ofPheo. Moreover, it also showed tumor targeting activity and a PDT-PTT synergistic effect. These resultsindicate that this multifunctional AuNR system with tumor targeting ability and GSH-sensitive linkageswould be highly efficient for noninvasive cancer treatment by integrating cancer imaging diagnostics andsynergistic therapy.
JongSeon Park 대한고혈압학회 2013 Clinical Hypertension Vol.19 No.1
Middle aortic syndrome (MAS) is very uncommon vascular pathology characterized by a long segmental narrowing or obstruction of the abdominal and/or distal thoracic aorta, commonly involving with the visceral and renal arteries. This syndrome may be presented with various physical signs of coarctation of the aorta, including resistant hypertension, renal insufficiency and/or mesenteric ischemia. Here, we report a case of a 64-year-old man with severe hypertension. He was diagnosed with MAS associated with stenosis of visceral and renal vessels by use of computed tomography and magnetic resonance angiography.
Jongseon Choe,Jinkoo Kim,In Su Cheon,원유진,나희준,김영명 한국분자세포생물학회 2003 Molecules and cells Vol.16 No.1
IL-4 is emerging as a candidate cytokine for the treatment of inflammatory and autoimmune diseases. We have reported that IL-4 has anti-angiogenic activity and inhibits the growth of human umbilical vein endothelial cells (HUVEC) in response to vascular endothelial growth factor (VEGF) or fibroblast growth factor-2 (FGF-2). Cell cycle analysis of this effect revealed that IL-4 arrests the growth of FGF-2- stimulated HUVEC in G0 + G1 phases. The absence of subdiploid cells showed that it did not induce apoptosis. Growth arrest was dose-dependent, but the percentage of G0 + G1 phase cells never exceeded 85%. An immunoblot analysis demonstrated that expression of p53 and p21Waf1 was increased and that of cyclin D1 and cyclin E decreased by IL-4. These results show that IL-4 inhibits endothelial cell growth by alte
자본구조에 따른 덤핑마진 차별적 산정의 WTO반덤핑협정 불합치성 연구
심종선(Jongseon Shim),한수진(Soojin Han) 산업통상자원부 2021 통상법무정책 Vol.- No.2
WTO 반덤핑 협정은 반덤핑관세를 결정하기 위한 계산구조를 다루면서 공정한 비교를 달성하기 위해 다양한 조정사항들을 포함하고 있다. 그 중 판매관리비를 생산원가 혹은 구성가치 계산시 가산하도록 하고 있는데, 많은 국가가 금융비용 혹은 이자비용을 판매관리비와 함께 가산하는 관행을 보이고 있다. 이러한 관행은 완전히 동일한 영업구조와 환경 하에 있는 기업이라 하더라도 부채율이 높을 수록 덤핑마진율이 인상되는 효과로 이어진다. 한국과 미국의 사례를 들어 그 관행을 구체적으로 기술하고, 회계학적 관점에서 그러한 관행이 갖는 불합리성을 지적하였다. 아울러 동 관행이 근거가 없을 뿐 아니라, 반덤핑협정상 비차별원칙에도 위반될 수 있음을 제시하였다. The WTO Anti-Dumping Agreement contains various adjustment methods to achieve fair comparison while addressing the calculation structure for determining anti-dumping duties. One of the various methods is adding SG&A expenses to cost of production or constructed value, whereas many countries show a practice of adding financial costs or interest expenses as well as SG&A expenses. Even in hypothetical situations, where exporters are in the same business environments, this particular practice leads to a higher dumping margin applied to the exporter with a higher debt ratio. Showing the practices of Korea and the United States as examples, the irrationality of the practice is pointed out from the view of Accounting. In addition to the legal and accounting groundlessness of this practice, it has the potential to violate the non-discrimination principle of the WTO Anti-Dumping Agreement.
박종선(Jongseon Park),왕기철(Gicheol Wang),김승해(Seunghae Kim),조기환(Gihwan Cho) 한국정보과학회 2013 정보과학회논문지 : 정보통신 Vol.40 No.1
네트워크 백본망의 지속적인 고속화로 인하여 장거리 사용자간 대용량 데이터 전송 서비스의 요구가 증대하고 있다. UDT(UDP based Data Transfer protocol)는 UDP 기반 전송프로토콜로써 TCP와 같은 전송 신뢰성과 안정성을 보장하면서 우수한 전송성능을 보인다. 최근 성능향상을 위해 다수의 채널을 이용하는 병렬전송기술이 시도되고 있으나, 네트워크 환경에 최적의 성능을 보이는 채널 수의 결정이 중요한 이슈이다. 본 논문에서는 UDT 기반 병렬전송에서 최적의 채널 수 예측기법을 제안한다. 먼저 실험을 통해 데이터 전송 거리 등 네트워크 환경에 따른 채널 수의 상관관계를 분석한다. 네트워크 환경의 변화에 따른 채널 수 결정 모델을 제시하고, 구현하여 제안된 모델의 유효성을 검증한다. With advance of high bandwidth backbone networks, it is dramatically increasing to cooperate between the users who are far from each other and make use of bulk data. UDT(UDP based Data Transfer protocol) is a UDP based application level data transfer protocol which designed to guarantee reliability as TCP. Parallel transfer techniques has recently been studied to increase its performance. Here, it is very important issue to decide the number of channels for best performance on a given network environment. In this paper, we propose an optimum channel prediction method for UDT parallel transfer protocol. With experimental examination, we first analyze a correlation between the number of channels and the distance for data transfer. Then a decision model to trace the number of parallel channels is suggested to reflect the trend of network situation variation. With implementing the model, the effectiveness of the suggested model is discussed in detail.