Correction: Bioinspired M-13 bacteriophage-based photonic nose for differential cell recognition

Moon, Jong-Sik,Kim, Won-Geun,Shin, Dong-Myeong,Lee, So-Young,Kim, Chuntae,Lee, Yujin,Han, Jiye,Kim, Kyujung,Yoo, So Young,Oh, Jin-Woo Royal Society of Chemistry 2017 Chemical Science Vol.8 No.2

<P>Correction for ‘Bioinspired M-13 bacteriophage-based photonic nose for differential cell recognition’ by Jong-Sik Moon <I>et al.</I>, <I>Chem. Sci.</I>, 2017, DOI: 10.1039/c6sc02021f.</P>

육우 햄에 대한 소비자 선호 분석

박종섭, 최양일, 공기서, 여순식 忠北大學校 農業科學硏究所 2012 農業科學硏究 Vol.28 No.3

The purpose of this study is to estimate the implicit prices and consumers’ preference by attributes on Korean beef cattle ham using choice experiments. Main attributes are the country of origin, non-antibiotic certification, HACCP certification, addition of Korean agricultural products and use of natural colors. The implicit prices of each attribute and level for country of origin are estimated as KRW 919.0 for Korean pork, KRW 2,173. for imported beef and KRW 5,232.9 for Korean cattle beef. The other estimated implicit prices are KRW1,762.9 for non-antibiotic certification, KRW 577.5 for HACCP certification, KRW 57.9 for addition of Korean agricultural products and finally, KRW 572.9 for use of natural colors. This study is expected to contribute to the decision-making process of Korean beef cattle farmers by providing useful quantitative information on attributes and price that are related to consumers’ preference on Korean beef cattle ham.

초임계 유체를 이용한 미세조류 바이오디젤의 직접 생산

유종훈,문성식 水原大學校 2014 論文集 Vol.28 No.-

In this study, we attempted to evaluate the feasibility of a supercritical methanol process for direct production of biodiesel from microalgae. The effects of various factors such as temperature, reaction time, water content and pretreatment on the efficiency of biodiesel conversion were investigated. The conversion efficiency increased with both temperature and extraction/conversion time. The supercritical methanol process produced a fatty acid methyl ester (FAME) yield of around 88% within 20 minutes. The optimal conditions for this process were found to be a microalgae/methanol ratio of around 1:9, a reaction temperature of about 270℃, and a reaction time of approximately 20 minutes. The effect of water content in microalgae samples on the FAME conversion was also evaluated. The supercritical methanol process was not affected by the water content up to 250 wt%. Our experiments demonstrated that the supercritical methanol process is more effective compared with conventional in situ transesterification processes.

Acriflavine-Guanosine 복합제 (AG60)의 조직내 분포에 대한 형광현미경적 연구

고정식,임수재,안의태,김진국,김상건,이경영,강종구,홍은경,정영신,유보림,한영복 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.1

내시경적 절제로 진단된 폴립 형태의 심재성 낭종성 위염 2예

허종현,조영화,성용완,유재훈,구동영,김갑식,노지훈,문원 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Gastritis cystica profunda (GCP) is a disease characterized by hyperplastic and significant extension of cystic dilatation of the gastric mucous glands, which results in a cystic lesion in gastric submucosa. It often occurs on the part of gastroenterostomy, but can be found in the stomach without any previous surgery. GCP has variable gross finding including solitary polyps, diffuse ones, submucosal tumors, and rare giant gastric mucosal fold. It is difficult to tell GCP from a cancerous lesion by gross finding that the disease demands a necessary tissue biopsy, though GCP is commonly showed as a benign in the progress. We report a case of GCP in polypoid types diagnosed by endoscopic polypectomy.

연령이 증가함에 따른 흰쥐 망막의 막대세포, 원뿔세포 및 바깥얼기층의 미세구조 변화

고정식,한종원,양남길,안의태 대한해부학회 1992 Anatomy & Cell Biology Vol.25 No.3

내시경적 밴드 결찰술로 치료한 출혈을 동반한 위 혈관이형성증 1예

김갑식,허종현,성용완,조영화,구동영,유재훈,노지훈,문원 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Gastric angiodysplasia is vascular ectasia in mucosa and submucosa of the gastric wall. It is an uncommon cause of upper gastrointesinal hemorrhage that may occur in the stomach or duodenum. There are many kinds of endoscopic treatments, such as argon plasma coagulation, electrocoagulation, heat probe, and submucosal injection of hypertonic saline mixed with epinephrine for gastric angiodysplasia. However, these treatment methods are associated with high rate of rebleeding. In order to avoid the recurrence, endoscopic band ligation has recently been used as an alternative method for endoscopic treatment of gastric angiodysplasia. We encountered a case of gastric angiodysplasia that presented with overt bleeding and anemia, and was successfully treated with endoscopic band ligation.

화학요법에 의한 설암조직의 CD44의 변화

김종식,길영기 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Despite enormous progress in current chemotherapeutic approaches for cancer, there is no advances of prognosis in malignant tumor of head and neck. Especially the prognosis in tongue cancer in which vessels are well developed is bad. Therefore, it is very important to distinguish the patient with infiltrating tumor and to find tumor marker which can play a key role in effective strategy for cancer treatment. Because there is little report about CD44 as prognostic marker in tongue cancer, this study was performed to investigate the alteration of CD44 expression in tumor specimens from eleven patients with tongue cancers before and after chemotherapy. In this study, CD44 was expressed strongly in spinous layer of specimen before chemotherapy and the expression of CD44 decreased significantly after chemotherapy, suggesting that the expression of CD44 is related with metastasis of tongue cancer. Taking above, the alteration of CD44 expression in tongue cancer tissue by chemotherapy suggests that CD44 are potentially expected to use in tongue cancer as prognostic factors.

원발성 위장관 악성 림프종의 임상적 고찰 : 치료 결과를 중심으로

원종호,백승호,홍대식,오도연,박희숙 순천향대학교 1994 논문집 Vol.17 No.4

저자들은 1984년 3월부터 1992년 12월까지 순천향 대학교 부속병원에서 원발성 위장관 악성 림프종으로 진단되었던 23명을 대상으로 다음과 같은 결론을 얻었다. 1. 대상 환자의 나이의 중앙치는 44(23-75)세로 남녀비가 2.8 : 1이었다. 2. 원발병소는 위 10예(43.5%), 소장 8예(34.8%) 및 회맹장 이행부위 5예(21.7%)였고, 병기 Ⅰ??기 8예(34.8%), Ⅱ??기 12예(52.2%), Ⅲ기 2예(8.7%), Ⅳ기 1예(4.3%)였다. 동반된 다른 장기는 주로 복부 임파절이었으며 폐 임파절 침범이 1예 있었고, 간을 침범한 경우가 1예, 위장과 소장에 병발한 경우가 1예 있었다. 조직학적 분류로는 중등도 19예(82.6%) 및 고도 4예(17.4%)였고 10예(43.5%)에서 B 증후가 있었다. 3. 치료를 시행한 20예중 Ⅰ??기 7예는 수술적 치료후 보조항암화학요법을 시행하였으며, Ⅱ??기 13예중 진단적 개복술후 완전절제가 확인된 3예는 보조항암화학요법을, 불완전절제로 확인된 7예는 관해유도 항암화학요법을 시행하였고, 3예는 항암화학요법만을 시행하였다. 4. 치료를 시행한 20예의 생존기간은 중앙치 43(4-100??개월이었으며, 3년 생존율 60.9%, 5년 생존율 40.6%였다. 5. Ⅰ??기 7예의 생존기간은 중앙치 42(11-100??개월이었으며, Ⅱ??, Ⅲ기 13예에서 치료에 대한 완전 관해가 9례(70%), 부분관해(15%), 무반응이 2례(15%)로 관해율은 85%였으며, 생존기간은 중앙치 44(4-52??개월이었다. 6. 완전관해자가 진행시까지의 관해지속기간은 중앙치 43(10-56??개월이었으며, 3년 무병생존율 79.1%, 5년 무병생존율 36.2%였다. Over a 8-year period(March 1984 through December 1992), 23 patients with primary gastrointestinal non-Hodgkin's lymphoma treated at Soonchunhyang University Hospital were analyzed with the following results; 1. The mean age of the patients was 43(23-75) years with male to female ratio of 2.8 : 1. 2. The primary sites of lymphoma were stomach in 10(43.5%), small intestine in 8(34.8%), and ileocecal area in 5(21.7%) and by modified Ann Arbor system, stage Ⅰ?? was 8(34.8%), stage Ⅱ?? was 12(52.2%), stage Ⅲ was 2(8.7%), and stage Ⅳ was 1(4.3%). Histologic classification by Working formulation revealed 19 cases(82.6%) of intermediate grade and 4 cases(17.4%) of high grade. B symptoms were observed in 10 cases(43.5%). 3. Treatments were performed in 20 cases as follows : In 7 cases with stage Ⅰ, complete surgical resection with systemic combined chemotherapy was performed. In 13 cases with stage ⅡE and Ⅲ, complete resection with systemic combined chemotherapy in 3 cases, incomplete resection with combined chemotherapy in 7 cases, and combined chemotherapy only in 3 cases. 4. Median survival duration of 20 treated patients was 43(4-100?? months and 3-year survival rate and 5-year survival rate were 60.9% and 40.6%, respectively. 5. Median survival duration of 7 cases with stage Ⅰ?? was 42 months(11-100??. In 13 cases with stage Ⅱ??, Ⅲ, response to treatment was complete remission in 9(70%), partial remission in 2(15%), and no response in 2(15%) resulting 85% of response rate and median survival duration was 44(4-52?? months. 6. Disease free survival rate of achieving a complete remission was 43(10-56?? months and 3-year disease-free survival rate and 5-year disease-free survival rate were 79.1% and 39.2%, respectively.

주정 중독 흰쥐에서 총담관 결찰이 혈청 및 간의 α-D-및 β-D-Glucosidase 활성에 미치는 영향

곽춘식,김여희,임종술 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.2

이 연구는 간담도 질환시 음주의 해로움에 대한 생화학적 배경의 일단을 밝히고자 시행한 실험으로서 급성 및 만성 주정 중독을 시킨 흰쥐에게 총담관결찰로 담즙울체를 야기시켜 혈청과 간의 α-D-glucosidase와 β-D-glucosidase의 활성도를 측정한 것이다. 쥐간의 lysosomal α-D-glucosidase 활성도는 총담관만 결찰한 군보다 만성 주정 중독 후 총담관을 결찰한 군이 총담관 결찰 후 7일부터 14일까지 덜 현저한 증가를 나타내었다. 총담관을 결찰한 군과 만성 주정 중독 후 총담관을 결찰한 군에서 간의 lysosomal acid β-D-glucosidase 및 cytosolic broad specificity β-D-glucosidase 활성도를 비교했을 때는 양군간에 별 차이가 없었다. 총담관을 결찰하고 14일 경과한 군과 총담관 결찰 14일 후 급성 주정 중독을 시킨 군에서 간의 lysosomal α-D-glucosidase, lysosomal acid β-D-glucosidase 및 cytosolic broad specificity β-D-glucosidase의 활성도를 비교했을 때는 양군간에 별 차이가 없었다. 쥐 혈청의 lysosomal α-D-glucosidase와 broad specificity β-D-glucosidase 활성도를 총담관을 결찰한 군과 만성 주정 중독 후 총담관을 결찰한 군을 비교했을 때는 만성 주정 중독 후 총담관을 결찰한 군이 총담관만 결찰한 군보다 더 현저한 증가를 나타내었다. 그러나 총담관을 결찰하고 14일 경과한 군과 총담관 결찰 후 급성 주정 중독을 시킨 군에서 혈청의 이들 효소의 활성도를 비교했을 때는 broad specificity β-D-glucosidase만 총담관 결찰 후 14일 경과한 군보다 총담관결찰 14일 후 급성 주정 중독을 시킨 군이 그 활성도가 더 높았다. 이들 성적 중에서 혈청의 lysosomal α-D-glucosidase와 broad specificity β -D-glucosidase의 활성도가 총담관만 결찰했을 때 보다 만성 주정 중독 후 총담관을 결찰했을 때 더 증가되고 아울러 혈청의 broad specificity β-D-glucosidase 활성도가 총담관 결찰 14일 후 급성 주정 중독을 시켰을 때는 총담관만 결찰한 후 14일 경과했을 때보다 그 활성도가 높은 것은 만성 주정 중독 및 급성 주정 중독시 담즙울체가 야기되면 담즙울체만 있을 때보다 간손상이 증폭된다는 것을 나타낸 결과라 생각되며 이성적은 간손상의 증폭으로 간에서 이들 효소의 누출일 증가된 것이라 할 수 있다. 따라서 이 성적은 담즙울체로 간손상이 있을 때는 음주를 해서는 안된다는 것을 뒷받침하는 자료라 하겠다. The activities of the liver and serum α-D and β-D-glucosidase were studied for cholestasis induced by common bile duct ligation and chronic ethanol intoxication developed, or cholestasis after acute ethanol intoxication for manifestation of the biochemical background of alcohol intoxication in hepatobiliary disease. The groups that received common bile duct(CBD) ligation after being chronically intoxicated with ethanol showed a marked increase at the 7th and 14th day after the ligation in the liver lysosomal α-D-glucosidase activities. However, the activities showd a lower degree than groups of the CBD lgation. The groups that received CBD ligation after being chronically intoxicated with ethanol showed a slight increase after the ligation in the liver lysosomal acid β-D-glucosidase and cytosolic broad specificity β-D-glucosidase activities, and the same was seen in the groups of the CBD ligation. At the 1.5th and 24th hours after the acute intoxication with ethanol which was done after 14 days of the CBD ligation, the rats showed a considerable increase in the liver lysosomal α-D-glucosidase, lysosomal acid β-D-glucosidase and cytosolic broad speciticity β-D-glucosidase activities, and the same was seen in the group sacrificed on the 14th day after the CBD ligation. The groups that received CBD ligation after being chronically intoxicated with ethanol showed a marked increase after the ligation in the serum lysosomal α-D-glucosidase and broad specificity β-D-glucosidase activities. However, the activities showed a far higher degree than groups of the CBD ligation. For the groups of acute intoxication with ethanol done after 14 days of the CBD ligation, the serum broad specificity β-D-glucosidase activities increased markadly, but the activities showed a higher degree than the group with the 14th day after the CBD ligation. In summary, especially, when the acute and chronic ethanol intoxication with cholestasis occurred, the serum lysosomal α-D-glucosidase and broad specificity β-D-glucosidase are higher than in cholestasis because of increased liver cell damage, which causes the enzyme to leak into the blood in great quantity. Accordingly, these results will be the data supporting the alcoholic drink is enzymologically harmful in hepatobiliary disease.