관상동맥 시술 도중 발생한 좌주간부 관상동맥 박리에 대한 스텐트 삽입 치료의 단장기 임상 결과 : acute and long-term results

이세환,이승환,홍명기,김영학,이철환,한기훈,송종민,강덕현,송재관,김재중,박성욱,박승정 대한내과학회 2004 대한내과학회지 Vol.66 No.6

목적 : 심도자 사용 시술과 관련된 좌주간부 관상동맥박리에 대한 적절한 치료는 아직 확실히 정립되지 않은 상태이다. 이에 본 연구는 좌주간부 관상동맥 박리에 대한 스텐트 삽입술의 단장기 임상결과를 후향적으로 분석하였다. 방법 : 좌주간부 관상동맥 박리에 대한 치료로 즉각적인 스텐트 삽입술을 시행하는 것이 안전하고 효과적인 방법임을 가설하였고, 이러한 즉각적인 스텐트 삽입을 시행한 10명의 환자를 대상으로 단장기적 임상경과를 의무기록 고찰과 전화 면담을 통해서 평가하였다. 결과 : 전체 환자 모두 처음부터 좌주간부 관상동맥에 유의한 협착을 가진 환자는 없었으며, 8명의 환자는 심도자의 조작으로 인한 박리가 발생한 경우였고(진단적 혈관 조영술 중에 3명, 유도 도자 조작 중에 5명), 나머지 2명은 다른 병변에 스텐트 삽입시술을 하는 중에 박리가 발생하였다. 이 10명의 환자에서 모두 즉각적인 스텐트 삽입술이 시행되었고, 4명의 환자에서 시술 도중 혈압 저하로 Intra-aortic Ballon Pump (IABP)를 장착하였다. 모든 환자에서 성공적으로 스텐트가 삽입되었고, 병원내 사망은 1명도 없었다. 6개월 추적 관상동맥 조영술은 8명의 환자에서 시행되었다. 혈관 조영상의 재협착(직경 협착 50% 이상)은 8명 모두에게서 관찰되지 않았으며, 퇴원 후 평균 31±25개월의 추적관찰 결과 주요 심장사건은 1건도 발생하지 않았다. 결론 : 비록 대상 환자가 적은 연구였지만 좌주간부 관상동맥 박리에 대한 스텐트 삽입술은 기술적으로 안전하고 빠르게 시행 할 수 있으며, 훌륭한 단장기적인 치료 효과를 보여준다. Background : The optimal treatment of patients with left main coronary artery (LMCA) dissection during catheter-based procedure remains uncertain. We retrospectively analyzed the acute and long-term results of bail-out stenting for LMCA dissection. Methods : In cases with significant LMCA dissection occurring during catheter-based procedure, prompt stent implantation may be safe and associated with favorable clinical outcome. We evaluated the acute and long-term results of bail-out stenting for LMCA dissection occurring during catheter-bases procedure in 1- patients. Results : Initially, there was significant stenosis of LMCA segment in these patients. Catheter-induced dissection occurred in 8 patients (during diagnostic angiography in 3 patients and guiding catheter manipulation in 5 patients). Two patients suffered dissection in the setting of stent deployment in other vessels. Therefore, bail-out stenting LMCA dissection was performed in a total of 10 patients. In 4 patients, hypotension developed and intra-aortic balloon pump was placed during procedure. Stents were successfully deployed in all patients. There was no in-hospital mortality. Six-month angiographic follow-up was performed in 8 patients. Angiographic restenosis(diameter stenosis 50%) was not observed in all patients at follow-up study. During a mean follow-up of 31±25 months after hospital discharge, there was no major adverse cardiac event (death, myocardial infarction, and target lesion revascularization). Conclusion : Bail-out LMCA stenting is technically feasible, and showed good acute and long-term results in a small series of patients.

발효조를 이용한 Monascus anka의 적색소와 황색소의 생산

강성국,임종환,정순택,김선재 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

Monascus anka를 이용하여 천연식용색소를 대량생산하기 위한 방법을 개발하기 위하여 발효조를 이용하여 적색소와 황색소의 색소생산의 최적 배양 조건과 생산된 색소의 색깔 특성을 조사하였다. Monascus anka 적색소와 황색소를 생산하였는데, 이들 색소는 균체내색소와 균체외 색소로 구분되었다. 균체의 적색소(ERP)는 494nm에서, 균체외 황색소(EYP)는 380nm에서, 균체내 적색소(IRP)는 506nm에서 그리고 균체내 황색소(IYP)는 388nm에서 최대 흡광도를 나타냈다. 적색소와 황색소 생산, 색조의 특성 및 균체증식력을 배양 온도, pH, 쌀가루 농도, peptone 농도, magnesium sulfate 농도, 통기량 및 교반속도에 대하여 조사한 결과 적색소 생산력은 30℃, 초기 pH 6.0, 쌀가루 농도 3~5%, peptone 농도 0.05%, magnesium sulfate 농도 0.25%, 통기량 0.1vvm 교반속도 300rpm의 조건에서 최대치를 보였으며, 이때 ERP, EYP, IRP 및 IYP는 각각 A_494nm 0.84, A_380 nm 0.71, A_506 nm 1.18, A_388 nm 1.10, L값은 각각 29.40, 6.44, 34,98, 8.94, a값은 각각 5.76, -1.08, 11.83, -1.55, b값은 각각 18-19, 3.41 27.26, 6.16 그리고 균체량은 7.4 g/l을 보였다. 또한 황색소 생산력은 온도의 경우 적색소 생산을 위한 최적온도 보다 높은 35℃ 부근에서 우수하였으며 초기 pH와 쌀가루 농도는 적색소 생산을 위한 최적조건과 같았고, 질소원과 무기염의 농도가 높을수록 그리고 통기량이 많을수록 황색소 생산력이 우수하였다. 적색소와 황색소 생산을 위한 발효조의 교반속도는 100~300 rpm이 적합하였다. Production of Red and Yellow Pigments from Monascus anda in a Jar Fermenter, Seong-Gook Kang, Jong-Whan Rhim, Soon-Teck Jung^* and Sun-Jae Kim. Department of Food Engineering. Mokpo National University Chonnam, 534-729, Korea - In order to develop the method for mass production of natural food colorant from Monascus anka, optimum cultivation conditions for producing red and yellow pigments by cultivating the mold in a jar fermenter and their color characteristics were investigated. The mold produced red and yellow pigments both intracellularly and extracellularly. These pigments showed unique light absorption characteristics with maximum absorption of 494, 380, 506, and 388 nm for extracellular red pigment (ERP), extracellular yellow pigment (EYP), intracellular red pigment (IRP), and intracellular yellow pigment (IYP), respectively. Optimum conditions for producing red pigments were found to be temperature 30℃, initial pH 6.0, rice powder 3~5%, peptone 0.05%, magnesium sulfate 0.25%, aeration rate 0.1vvm. Optimum temperature for producing yellow pigments was around 35℃ which is higher than that of producing red pigments. The initial pH rice powder concentration for producing yellow pigments were the same as those of producing red pigments. The higher concentration of nitrogen source and inorganic salt, aeration rate, the more the yellow pigments were produced. Them optimum agitation speed was 100~300 rpm for pigment production.

경피적 승모판막 성형술 전후 측정방법에 따른 승모판구 면적

성인환,이종구,박종훈 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

To assess mitral valve area(MVA) before and after percutaneous mitral ballon valvuloplasty (PMV), MVA was calculated by 2-D and Doppler (pressure half time) echocardiography before and 1 day after PMV. Also the catheterization derived MVA was calculated by modified Gorlin's fomula before and immediately after PMV. Among a total of 63 patients performed successful PMV, 29 patients were female and 24 patients were male. The age of the patients were between 21 and 68 years with the mean age of 42±12 years. On the EKG 34 patients showed a sinus rhythm 29 patients showed an atrial fibrillation. PMV was performed using Inoue balloon in 31 patients and double balloon in 32 patients with mitral stenosis. After PMV MVA by Gorlins formula, 2-D and Doppler echocardiography was increased from 0.84±0.22㎠ to 1.86±0.47, 1.86±0.31 and 1.76±0.34㎠, respectively (p<0.01). Before PMV MVA determined by the Gorlin's formula correlated closely with MVA by 2D and Doppler echocardiography (r=0.66 and r=0.69 respectively). However, after PMV MVA determined by the Gorlin's formula did not correlate well with MVA by 2-D and Dopper echocardiography (r=0.32 and r=0.41) However, after PMV MVA determined by the Gorlin's formula did not correlate well with MVA by 2-D and Doppler echocardiography (r=0.32 and r=0.41 respectively). Then Correlation between the 2-D planimeteral MVA and doppler derived MVA was good (r=0.82) After PMV the discrepancy of correlation may be bue to lack of simultaneous meusurements of MVA by echocardiogrphy and catheterization. Immediately after PMV the dramatic hemodynamic changes by have a disturbing effect of MVA measurement by Gorlin's formula. In conclusion, 2-D and Doppler echocardiography was non-invasive and effective method for assessment of MVA before and after PMV.

일부 수영장 욕수 및 이용객 urine내 Trihalomethane 농도

문경환,손종렬,김영환,변상훈,배은상 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

Chlorination of swimming pool water leads to many chlorinated products. The most frequent derivative is trihalomethane(THMs). This study was performed to investigate the distribution of THMs in swimming pool water and ambient air, and to determine whether THMs concentrations in swimmers' urine Were influenced significantly after swimming. Water samples were collected from 22 indoor and outdoor swimming pools. Concentrations of THMs in swimmers' urine determined before and after their stay in swimming pools. Results of the study as follows. 1. The concentrations of THMs in the indoor swimming pools water(41.85±73.22㎍/L) were significantly increased(p<0.05) in comparison with that of outdoor swimming pools (10.15±15.45㎍/L). The average concentration of THMs in indoor ambient was 51.2㎍/㎥, which was significantly higher than that of air quality. 2. As a results of regression analysis between THMs and water quality factors, the concentration of pH, residual chlorine and KMnO₄ consumption were highly correlated in indoor swimming pools. 3. In almost all cases, only CHCl₃ was quantifiable. The proportions of THMs in urine correlated roughly with those in water and the secretion of THMs increased significantly after swimming in the pools.

맥반석의 용출시험 및 중금속 흡착특성

김종부,신명국,성낙환,최문정,김경주,이동석 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

This experiment was done to investigate the leaching and adsorption properties of heavy metals on porphyry. The comparison with respect to the leachability of heavy metals from porphyry between the Korea Standard Leaching Test (KSLT) and the Toxicity Characteristic Leaching Procedure (TCLP) was carried out. The fractional composition of leachate and the total concentration of heavy metal of porphyry were studied through Sequential Extraction Procedure (SEP) and EPA Method 3050. Adsorption experiment of porphyry has pointed out that the optimum dosage of porphyry for 50ppm Pb was over 10g/L, the effective particle size for absorption was below 200 mesh and the optimum pH was about 7. From the Freundlich' adsorption equation, l/n was 1.0722, and k was 0.0041. After adsorption, the fractional composition of Pb was changed. The exchangeable, carbonate, reducible fractions were increased, and the organic fraction was not changed, and the residual fraction was decreased.

佛蘭西에 있어서의 半封建的 地主制의 成立과 農民層의 對應

朱宗桓 東國大學校 1974 論文集 Vol.13 No.-

Iago의 世界

李鐘歡 群山大學校 1984 論文集 Vol.7 No.-

My subject is the world of Iago. I mean simply the imaginative environment that Othello asks us to enter when we read it. Great plays, as we know, do present us with something that can be called a world, a microcosm - a world like our own in being made of people, actions, situations, thoughts, feelings, and much more, but unlike our own in being perfectly, or almost perfectly, significant and coherent. In a play's world, each part implies the other parts, and each lives, each means, with the life and meaning of the rest. However, there appear many Vices in Morality Plays and Interludes, who contain both foolish qualities of comedy and devilish ones of tragedy. The comic qualities of Vice succeeded to Shakespeare's Fool characters and the wicked ones of Vice showed the way to the Iago. Shakespeare's Fools satirize on the follies in aristocratic society. In other words, the world of Romance is the very target on which they'd give an criticism. But to carry their jokes a little too far would develop into the negation of everything and the love of evil for evil's sake. So Iago does a 'motivelsss malignity' as Vice torments other characters without any hatred. Iago's world is devil's one while Othello's world is Romance's one. The conflict which these two worlds make in colliding with each other is the theme of the tragedy Othello.

發展指向的 人間觀

姜宗煥 조선대학교 학생지도연구소 1987 生活指導硏究 Vol.9 No.-

국내 콘크리트 기준의 발전 방향에 대한 고찰

심종성,최장환,문도영,박성재 漢陽大學校 工學技術硏究所 2002 工學技術論文集 Vol.11 No.-

유럽 각국의 규준을 통합한 유로 Code의 등장과 북미지역을 중심으로 한 기술통합의 흐름과 같은 Global Network화의 추세에 적극적으로 대처하고자 Asia Concrete Model Code(ACMC)의 제정이 제안되었다. 현재까지 ACMC 위원회는 LevelⅠ과 Level Ⅱ의 draft를 완성하였으며, Level Ⅲ에서는 국가/지역조건을 고려한 실제적인 지침을 준비하고 있는 단계이다. 따라서 본 연구에서는 각 시방들을 비교·분석하고 현재 제안된 ACMC Level Ⅲ Document 및 Perforomance Based Design과 관련된 문헌들을 고찰함으로써 국내현황에 적합한 ACMC Level Ⅲ Document의 작성방안을 제안하고자한다. Asian Concrete Model Code (ACMC) was proposed to cope with appearance of Euro-Code and a trend of Global Network such as a flow of the technique unification of North America. ACMC Committee has completed two drafts of LevelⅠ and LevelⅡ. Also, prectial specification considering national/regional condition is being prepared in draft of Level Ⅲ Document. On the study, each specification was analyzed and compared and a number of references were studied in order to propose ACMC Level Ⅲ Document considering domestic conditions.

金陵 松竹里遺蹟

申鍾煥 嶺南考古學會 1990 嶺南考古學 Vol.- No.7