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      • Diethylstilbestrol계가 노랑초파리의 발육에 미치는 영향

        김택수,김종세,조남기 조선대학교 부설 유전생물공학연구소 1991 유전생물공학연구지 Vol.1 No.1

        Four strains of Drosophila melanogaster : one wild strain gathered from the native inhabitant group on Ssangchon-dong in Kwangju, Korea, from May 10 to 23, 1988 and three strains bred and kept in incubators of Kwangju Teachers college for many years-namely, Oregon-R, cinnarbar brown and SD-72 were taken for this experiment to find the effects of two medicines are so constitued Diethylstilbestrol, Euvestrol, and Stilbestrol (Jungwon pharm. Co.) respectively, on the development and eclosion of Drosophila melanogaster. Eggs and imagines of these strains were given Euvestrol and Stilbestrol, and bred in incubators separately, and the following results were obtained from observation. When the laid eggs of Drosophila melanogaster were given Euvestrol Inj., no difference was found by strains, but there was difference by quantity of medicines given. When the imagines of Drosophila melanogaster were given Euvestrol Inj., no difference was observed by strains, but some difference by concentration of medicines with serious effect in high concentration. When the laid eggs of Drosophila melanogaster were given Stilvestrol tab., difference of effects was observed neither of strains by quantity of medicines. When the imagines of Drosophila melanogaster given Stilbestrol tab., showed little difference of effects among the four strains, and no difference by quantity of medicines

      • KCI등재

        Tardive Dyskinesia 에 대한 Sodium Valproate 의 치료효과에 관한 연구

        禹種仁,權俊壽,洪澤裕 大韓神經精神醫學會 1987 신경정신의학 Vol.26 No.4

        We performed the double-blind placebo-controlled study to investigate the therapeutic effect of sodium valproate known as GABA-ergic agent on tardive dyskinesia. 15 out of 31 patients were treated with sodium valproate (maintenance dose: 1500-2700㎎) and the rest of them were treated with placabo over 8 weeks. We checked the severity of tardive dyskinesia by TDRS (Tardive Dyskinesia Rating Scale, Simpson et al, 1979) just before treatment, the 4th week, the 8th week and the 12th week following beginning of treatment. We checked the serum level of sodium valproate at the 4th weeks and the 8th weeks since the beginning of treatment. The results were as follows: 1) Both TDRS scores of 4th week and 8th week were significantly low compared with those of pretreatment in the group treated with sodium valproate (P<0.001), but TDRS scores returned to the pretreatment score at 12th week (4 weeks after withdrawal of medication). There was no significant relationship between serum level of sodium valproate and TDRS total scores. 2) All of the TDRS scores of 4th week, 8th week, and 12th week were significantly low compared with those of pretreatment in the group treated with placebo.(P<0.01) 3) TDRS scores of the group treated with sodium valproate were not significantly different from those of the group treated with placebo at the time prior to treatment, 4th week, 8th week and 12th week.

      • 성인형 당뇨병 환자에서 피부생검을 이용한 표피하 모세혈관 기저막 두께의 변화에 관한 연구

        김원학,오금탁,김만우,장경식,채종구,조건국 朝鮮大學校 附設 醫學硏究所 1987 The Medical Journal of Chosun University Vol.12 No.1

        Thickening and proliferation of capillary basement membrane is a generalized phenomenon in diabetes mellitus and has been described in many organs including heart, kidney, pancreas, retina etc. While such changes are specific, it is difficult to obtain specimens from those organs. We took the specimens from the medial surface of the thing of 33 diabetics and 4 healthy persons as controls by means of punch biopsy. The measurement carried out by normogram and electron microscopic technique. HbA_(1c) values were also measured simultaneously. 1. The HbA_(1c) values are higher in diabetics than in control group (p<0.01). 2. The subepidermal capillary basement membrane thickness of the diabetics : 30% of the 5 th decade population, 53.9% of the 6 rh decade population and 83.3% of the 7th decade population showed more rhan 3,000 A. Whereas all the controls showed below 3,000 A. 3. The subepidermal capillary basement membrane thickness did nor increase significantly with the duration of the disease. 4. In cases of high subepidermal capillary basement membrane thickness, HbA_(1c) showed significant increase. (p<0.01).

      • 하수슬러지 처분 및 재활용 방안에 관한 연구 : 경상남도를 중심으로 Focused on Kyongsangnamdo

        이창호,강신탁,김종오 경상대학교 환경보전연구소 2000 環境保全硏究所報 Vol.8 No.-

        The purpose of this study was to analysis the disposal and reuse methods of sewage treatment plant sludge in Kyongsangnamdo. The present practice of sewage sludge management was surveyed and evaluated. The sewage sludge generation amounts in future were estimated and the regulations concerning sewage sludge were reviewed. Considering environmental impacts and costs the disposal and reuse alternatives were established and the effective methods were recommended. The results were as follows : 1. While the amount of sewage sludge generation in Kyongsangnamdo was about 26 thousand tons in 1997. a amount of sewage sludge in 2001 would be estimated to increase up to 59 thousand tons due to new facility constructions. These large increase of sewage sludge needs the effective disposal and reuse alternatives. 2. Considering current cost of sewage sludge management. the economical alternatives were successively composting. landfill. ocean dumping. and incineration. But, the regulation trends to prohibit the sewage sludge from direct landfilling and ocean dumping. the other alternatives must be considered. 3. Considering regional conditions of Kyongsangnamdo. the sewage sludges in urban area were recommended to incinerate and reuse as landfill cover. However, the sludges in rural area was recommended to compost and reuse as agricultural fertilizer.

      • KCI등재후보

        단량체 및 무기질 filler 조성 변화에 따른 복합레진의 유변학적 특성

        이인복,이종혁,조병훈,손호현,이상탁,엄정문 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.6

        Objectives. The aim of this study was to investigate the effect of monomer and filler compositions on the rheological properties related to the handling characteristics of resin composites. Methods. Resin matrices that Bis-GMA as base monomer was blended with TEGDMA as diluent at various ratio were mixed with the Barium glass (0.7 um and 1.0 um), 0.04 um fumed silica and 0.5 um round silica. All used fillers were silane treated. In order to vary the viscosity of experimental composites, the type and content of incorporated fillers were changed. Using a rheometer, a steady shear test and a dynamic oscillatory shear test were used to evaluate the viscosity (η) of resin matrix, and the storage shear modulus (G′), the loss shear modulus (G″), the loss tangent (tanδ) and the complex viscosity (η*) of the composites as a function of frequency ω= 0.1-100 rad/s. To investigate the effect of temperature on the viscosity of composites, a temperature sweep test was also undertaken. Results. Resin matrices were Newtonian fluid regardless of diluent concentration and all experimental composites exhibited pseudoplastic behavior with increasing shear rate. The viscosity of composites was exponentially increased with increasing filler volume%. In the same filler volume, the smaller the fillers were used, the higher the viscosities were. The effect of filler size on the viscosity was increased with increasing filler content. Increasing filler content reduced tanδby increasing the G′further than the G″. The viscosity of composites was decreased exponentially with increasing temperature.

      • Characterization of the Agronomic traits in the Inbred line derived from Double Haploid line using Pollen of Maize in the Crossing between Geumgang and CIMMYT’s wheat

        Jong-Nae Hyun,Chon-Sik Kang,Jae-Bok Hwang,Ki-Yeol Chung,Young-Dae Choi,Jong-Tag Youn,Eul-Soo Yun,Jee-Yeon Ko,Ji-Yeon Kim,In-Seok Oh,Sang-Jong Lim 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07

        Wheat is one of the most important food crops in the world and provides 20% of nutritional requirement to the consumers in developing countries. The consumption per capita of wheat is persistent but the self-sufficiency has decreased owing to the less competitive world market and double cropping system with rice in Korea. This study was conducted to obtain baseline data on the selection lines with early maturity and good agronomic traits. Geumgangmil, a leading Korean variety, was crossed with CIMMYT’s line, and a DH (double haploid) line was released using pollens of Maize in Mexico. The 71 inbred lines were grown in fields at NICS, Miryang. The culm length of inbred lines were normally distributed from 37cm to 106cm, though that of the P1 (Geumgangmil) was 71 and P2 (CIMMYT’s Line) was 77cm. Especially, some lines were very short and measured below 50cm. The spike lengths of most of the lines were longer than that of P1 (7.5cm), but were normally distributed. The number of spikelet was less than that in P2 (19ea.), but was more than P1(10ea.). The heading day of most of the lines was between P1 (11th April) and P2 (25th April) and the maturity day of the lines was similar to P1 (1st June) but 5 lines showed 2~6 days shorter maturity period than that of P1. However, 20 lines were found to have 2~10 days longer maturity period than that of P2.

      • KCI등재후보

        Evaluation of Nitrogen Fixation between Supernodulating Soybean Mutants and their Wild- Types Using 15N in Field Conditions

        Jong-Tag Youn,반규정,Yong-Hwan Ryu,Shinji Shimada,Choon-Ki Lee,김선림,Sea-Jung Seo,이석하 한국작물학회 2008 Journal of crop science and biotechnology Vol.11 No.1

        Improvement of N2 fixation by symbiotic rhizobia is considered an effective means for enhancing its productivity without high input of nitrogen (N) fertilizer. Several methods to improve N2 fixation have been proposed including the use of supernodulating mutants. The objective of this research was to identify the varietal difference in N and N2-fixation ability among the soybean supernodulating mutants, SS2-2 and Sakukei 4, with different nodulation abilities using 15N in field conditions in both Korea and Japan. The dry weight (DW) was higher in wild-type soybeans. The distribution rate of DW in each plant part was high in seeds of supernoduating and wild-type soybeans but high in stems and leaves of non-nodulating mutants. Although the supernodulating mutants had a low DW rate at maturity, they showed a similar N2 fixation ability compared with wild-type. Supernodulating mutant plants mainly obtained N from N2 fixation, while soil N was the main resource for obtaining N in non-nodulating mutants. The percentage of N derived from atmospheric dinitrogen (Ndfa) was higher in supernodulating mutants than in wild-type and relatively high in seeds between plant parts at maturity. In particular, supernodulating mutants showed higher N content in roots than those of wild-type and non-nodulating mutants. It was considered that supernodulating mutants have the advantage of saving nitrate in soil and being beneficial for N absorption of subsequent crops due to their conserving more N in the field and releasing considerable amounts of N from roots and leaves fallen to the soil.

      • KCI등재후보

        Waterlogging Effects on Nitrogen Accumulation and N₂ Fixation of Supernodulating Soybean Mutants

        Jong-Tag Youn,반규정,이재은,김욱한,Hong-Tae Yun,Young-Up Kwon,Yong-Hwan Ryu,이석하 한국작물학회 2008 Journal of crop science and biotechnology Vol.11 No.2

        Soybean is sensitive to waterlogging stress, leading to reduce their growth and yield significantly. The objective of this study was to characterize the relative sensitivities of biomass accumulation and specific nodule activity under waterlogging stress between supernoduating mutants, 'SS2-2' and 'Sakukei 4' and their wild-type soybeans, 'Sinpaldalkong 2' and 'Enrei', respectively. Flooding treatment was performed to soybean plants grown in a pot by waterlogging for 15 days from the beginning bloom (R1) stage under natural light. The nodule number and weight were considerably decreased by waterlogging stress. The bleeding sap rate of waterlogging soybean plants was decreased by 78-80% in supernodulating mutants and 65-74% in their wild types compared to control plants. The relative ureide-N content was also decreased by waterlogging and the reduction was high in supernodulating mutants. This may cause the massive reduction of shoot and root dry weight and leaf area in waterlogged soybean plants. There was a varietal difference in response to the waterlogging stress. During the waterlogging, supernodulating mutants maintained higher spad value than their wild types. Particularly, the difference between soybean varieties was clear in low rank leaves from the top. Also, supernodulating mutants showed a weak waterlogging tolerance than their wild types. Under waterlogging conditions, massive nodules were considerably destroyed and specific nodule activity after waterlogging may not be recovered when compared to their wild-type soybeans. Supernodulating mutants showed lower seed yield than their wild types in waterlogging conditions. Soybean is sensitive to waterlogging stress, leading to reduce their growth and yield significantly. The objective of this study was to characterize the relative sensitivities of biomass accumulation and specific nodule activity under waterlogging stress between supernoduating mutants, 'SS2-2' and 'Sakukei 4' and their wild-type soybeans, 'Sinpaldalkong 2' and 'Enrei', respectively. Flooding treatment was performed to soybean plants grown in a pot by waterlogging for 15 days from the beginning bloom (R1) stage under natural light. The nodule number and weight were considerably decreased by waterlogging stress. The bleeding sap rate of waterlogging soybean plants was decreased by 78-80% in supernodulating mutants and 65-74% in their wild types compared to control plants. The relative ureide-N content was also decreased by waterlogging and the reduction was high in supernodulating mutants. This may cause the massive reduction of shoot and root dry weight and leaf area in waterlogged soybean plants. There was a varietal difference in response to the waterlogging stress. During the waterlogging, supernodulating mutants maintained higher spad value than their wild types. Particularly, the difference between soybean varieties was clear in low rank leaves from the top. Also, supernodulating mutants showed a weak waterlogging tolerance than their wild types. Under waterlogging conditions, massive nodules were considerably destroyed and specific nodule activity after waterlogging may not be recovered when compared to their wild-type soybeans. Supernodulating mutants showed lower seed yield than their wild types in waterlogging conditions.

      • KCI등재후보

        Effect of N Fertilizer Top-dressing on N Accumulation and N2 Fixation of Supernodulating Soybean Mutant

        Jong-Tag Youn,반규정,Jae-Eun Lee,Sung-Kook Kim,Jin Song,김욱한,이석하 한국작물학회 2009 Journal of crop science and biotechnology Vol.12 No.3

        Increased application of nitrogen (N) fertilizer top-dressing during growth is an effective option for enhancing N supply to soybeanplants. SS2-2 was characterized by the superior ability of symbiotic N2 fixation at the level of 30 kg N ha-1. But, the response ofnitrogen fixation ability of supernodulating soybean mutant, SS2-2, to N fertilizer application rate remains unclear. The objective ofthis experiment was to compare the response of N fertilizer top-dressing on N accumulation and N2 fixation between supernodulatingmutant, SS2-2, and wild-type, Sinpaldalkong 2. The effect of N fertilizer top-dressing (0.6 g N pot-1 top-dressing) on the nitrogenaccumulation and redistribution were compared between SS2-2 and Sinpaldalkong 2. N fertilizer top-dressing at R1 stage increase inplant dry weight, relative growth rate (RGR), net assimilation rate (NAR), nitrogen harvest index (NHI), and N redistribution (NR). SS2-2 showed highest N concentration, 65.0 mg N g DW-1, followed by Sinpaldalkong 2 and En1282, and the N content per plant didnot show a significant difference between SS2-2 and Sinpaldalkong 2. The N2 fixation rate was significantly reduced by N top-dressing,but the amount of N2 fixation was not changed due to an improved dry weight without changes of N concentration. In addition,SS2-2 showed higher NHI, NR and NRE than Sinpaldalkong 2. These results suggested that supernodulating soybean mutants, SS2-2, could be characterized by high N concentration and N2 fixation regardless of N fertilizer top-dressing due to a higher nitrate toleranceof supernodulating mutants than that of wild-type.

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