Snorer의 앙와위와 직립위에서의 상도의 크기

이계형,김종철 전남대학교 치과대학 1995 전남치대논문집 Vol.7 No.1

The purpose of this study was to compare and evaluate the upper airway structure between the snorers and asymptomatic control subjects depending on the positional change. Lateral cephalograms in the upright and supine position were taken in 25 female snorers and 20 female asymptomatic control subjects. The length and the area of the soft palate, tongue and airway were measured and evaluated statistically. The results obtained were as follows : 1. The snorers showed longer and higher tongue, narrower and longer airway, inferiorly positioned hyoid bone, longer and broader soft palate and narrower hypopharynx than the control subjects both in the upright and supine position. In addition, the snorers showed broader tongue area and narrower oropharynx area than the control subjects in supine position. 2. Depending on the positional change from upright to supine position, the controls and the snorers showed decreased airway length and superior positioned the hyoid bone. In addition, the snorers showed decreased tongue length and height, airway length and thickness and oropharynx area, but increased tongue area and soft palate area.

Snorer의 앙와위와 직립위에서의 상기도 크기

김종철,조홍규,이계형 대한치과교정학회 1996 대한치과교정학회지 Vol.26 No.1

Snorer와 정상인의 상기도 부위 연조직의 차이를 비교하며, 자세의 변화에 따른 snorer와 정상인의 상기도 부위 연조직 크기의 변화를 알아보고자 여성에서 snorer 25명과 정상군 20명을 대상으로 직립위와 앙와위에서 측모 두부 방사선 계측 사진을 촬영한 후 연구개, 혀 및 상기도에 관한 거리와 면적을 계측하고 통계학적으로 분석하여 다음과 같은 결과를 얻었다. 1. 직립위와 앙와위에서 snorer군은 정상군에 비해 혀의 길이가 길고 높이가 높았으며 기도가 좁고 길며 설골은 하방에 위치하였고 넓은 연구개와 좁은 hypopharynx를 가졌다. 앙와위에서 snorer군은 이와 더불어 정상군보다 더 넓은 혀와 더 좁은 oropharynx를 가졌다. 2. 직립위에서 앙와위로 자세의 변화에 따라 정상군과 snorer군 모두에서 기도의 길이가 감소하였고 설골이 더 상방위치 되었다. snorer군에서는 이와 더불어 혀의 길이와 높이, 기도의 두께와 oropharynx 면적은 감소하였으며 혀와 연구개 면적은 증가하였다. The purpose of this study was to compare and evaluate the upper airway structure between the snorers and asymptomatic control subjects depending on the positional change. Lateral cephalograms in the upright and supine position were taken in 25 female snorers and 20 female asymptomatic control subjects. The length and the area of the soft palate, tongue and airway were measured and evaluated statistically. The results obtained were as follows: 1. The sonorers showed longer and higher tongue, narrower and longer airway, inferiorly positioned hyoid bone, longer and broader soft palate and narrower hypopharynx than the control subjects both in the upright and supine position. In addition, the snorers showed broader tongue area and narrower oropharynx area than the control subjects in supine position. 2. Depending on the positional change from upright to supine position, the controls and the snorers showed decreased airway length and superior positioned the hyoid bone. In addition, the snorers showed decreased tongue length and height, airway length and thickness and oropharynx area, but increased tongue area and soft palate area.

경골어류에 있어서 알부민과 글로블린의 분리 추출에 관한 연구 : Ⅰ. 틸라피아에 있어서 알부민과 글로블린의 분리 추출 Ⅰ. Classification of a Albumin and Globulin in Tilapia spp

윤종만,김계웅 건국대학교 1989 論文集 Vol.29 No.2

This study were taken to isolate albumin and globulin fractions from the serum of tilapia sap., Tilapia mossambica, by physico-chemical analyses such as the classical salting- out, dialyses, electrophoretic method, ion-exchange chromatography and gel filtration chromatography. The result obtained in these experiments were summarized as tool lows: 1.The albumin fraction is composed of several components possessing relatively higherelectrophoretic mobilities and lower molecular sizes than the globulin components. 2.The molecular weight of albumin component was 89,000 and it possessed a BPB-binding ability. 3.Non of the albumin components was found to fit completely the definition of mammalian serum albumin. 4.The molecular weight of the globulin components was more than 295,000. 5.The correlation coefficient of the albumin/globulin ratio by BCG and blood analyzer was +0.599.

트리암시놀론아세토나이드 함유 구강점막 필름제의 제제설계 및 평가

이계주,박종범,신광현,이덕근,황성주 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-

To design and evaluate the double-layered mucoadhesive film preparation for the treatment of aphthous stomatitis, the film consisting of an adhesive layer containing triamcinolone acetonide and impermeable protective layer was prepared by a solvent-casting evaporation technique and subsequent drying. The polymers, Polycarbophil®, Carbopol®, CMC and gelatin, swell appoximately 2 times its volume in 30 minutes when added to water. In vitro adhesive time was longer than 8hrs and adhesive force was 177-482g/㎤. The diffusion rate of triamcinolone acetonide from film was faster than that of commercial tablet but slower than that of the film. the effect of plasticizer on the protective layer showed that the more amount of plasticizer, the greater elongation, the lesser tensile strength. The stability of drug in the film revealed that no significant reduction in the content of triamcinolone acetonide during a period of six months at room temperature and 40℃ 75% RH. Drug deposit amount permeated through hsmster cheek pouch mucosa from film was greater than that of control film and tablet. In human oral mucosa, adhesive time was between 2.38∼2.83hrs. The adhesive feeling to the human muoscal membrane of sample was better than compared with commercial film and tablet.

Ag 가 첨가된 비정질 유리반도체 As_2S_3의 물리적 특성

이종록,桂善姬 梨花女子大學校 韓國生活科學硏究院 1987 韓國生活科學硏究院 論叢 Vol.40 No.-

비정질 유리 반도체 As_2S_3에 Ag를 0, 5.7, 9.1, 12. at%로 첨가하여 thermal evaporation방법으로 박막 시료를 만들어 직류 전기 전도도, 광 흡수도를 측정하였다. X선 회절 실험 결과 각 시료는 비정질임이 확인되었다. 273K에서 373K 온도 영역에서의 직류전기 전도도는 7.04x10^-17(Ω^-1cm^-1)에서 8.66x10^-12(Ω^-1cm^-1_의 값을 나타내며 Ag의 농도가 증가함에 따라 직류 전기 전도도는 증가하였다. 직류 전기 전도도는 σ=σ_0exp(-ΔE_α/KT)의 관계식을 만족하고 광학적 에너지 gap은 Ag의 농도가 증가함에 따라 2.34, 2.12, 1.89, 1.78eV로 감소하였다. E_-ΔE_α의 값은 Ag의 농도에 관계없이 거의 일정하였다. D.C. electrical conductivity, optical absorption experiments on glassy semiconductor As_2S_3+Ag for which the Ag concentration is 0, 5.7, 9.1, 12.3 at. % are investigated. The thin film samples are prepared by the thermal evaporation method. From the result of X-ray diffraction experiment, it was convinced that each sample was amorphous semiconductor. Over the temperature range from 273˚K to 373˚K, the d.c. conductivity of the investigated samples is 8.66x10^-12(Ω^-1cm^-1)∼7.04c10^-17(Ω^-1cm^-1). As Ag concentration increases, the electrical d.c. conductivity increases. D.C. conductivities are proportional to inverse of temperature and satisfy the relation σ=σ_0exp(-ΔE_α/KT). The optical energy gap decreases with the Ag concentration having the value of the range from 2.34eV to 1.79eV. It is also shown that the value of difference E_g-ΔE_α is independent of Ag concentration.

韓國産 미꾸리에 關한 育種·繁殖學的 硏究 : Ⅴ. Ultrastructures Changes of Pituitary Gland and Testes in Male Loach Ⅴ. 미꾸리 수컷의 腦下垂體와 精巢의 微細構造

윤종만,노순창,김계웅,박홍양 건국대학교 동물자원연구센터 1993 動物資源硏究誌 Vol.18 No.-

본 연구는 1992년 3월부터 5월까지 자연채광 상태의 건국대학교 양어실습장에서 사육중인 한국산 미꾸리 수컷(Misgurnus anguillicaudatus)의 뇌하수체와 정소의 조직형태학적 변화를 이해하기 위해서 실시되었다. 미성숙 시기인 3월의 뇌하수체와 정소의 미세구조와 5월경의 성숙단계인 각 조직간의 발달상황을 비교 분석하기 위해서 광학 및 투과형 전자현미경을 이용하였다. 뇌하수체의 성선자극 호르몬이 분비되는 부위(GTH)의 발달은 정소의 주기적인 발달단계와 대체로 일치한다. 성성숙 지수(GSI)는 4월부터 5월에 이르는 시기에 증가하다가 정자세포와 정자의 수가 증가되는 5월에 가장 높게 나타났다. 하나의 小葉 속에 발달단계가 다른 nest가 들어있더라도 같은 정자형성 단계에 속한다. 미성숙 단계에서는 이형염색질이 분산되어 있다가 성숙 단계에서는 핵이 진하고 균질한 상태로서 존재한다. 핵막은 분화초기에 나타난다. 제1차 정모세포에는 15개 이상의 작은 미토콘드리아가 두부의 세포질 주변에 있다가 발달함에 따라 2개의 커다란 미토콘드리아로 변화되면서 한쪽으로 튀어나온 부위 주변에 위치하게 된다. 정자 중편부의 주위에는 미토콘드리아초와 외측 섬유소로 둘러싸여져 있다. This study was undertaken to understand the histomorphological changes of pituitary gland and testis of Korea loach(Misgurnus anguillicaudatus) under natural circumstances from March to May 1992. Sexual maturation was studied on 50 males Korean loach(Misgurnus anguillicaudatus). The results obtained in this study were as follows: The ultrastructures of the gonadotrophs largely parallel the cyclical changes in the testes. Gonadosomatic indices(GSI) increased from April to May, and showed the peak in May, coinciding with the increase of spermatids and spermatozoa in male. Each nest of cells belongs to one spermatogenetic stage, although nests at different stages can be found within the one lobule. At first heterochromatin is dispersed and then is condensed. In mature gamete, the nucleus is dense and homogeneous. The nuclear membrane appeared at the beginning of differentiation. In the primary spermatocytes, the small mitochondria are abundant over the outer cytoplasm. In the latter, the two large mitochondria are located over the cytoplasm. During cell differentiation, the cytoplasm decrease and the nucleus increases. Sperm mitochondria are assembled into an organized sheath surrounding the outer dense fibres and axoneme of the flagellar midpiece.

회체의 진동신호 해석용 보간기법에 관한 비교

박준용,조계현,박종연 강원대학교 정보통신연구소 2004 정보통신논문지 Vol.8 No.-

This paper compares error values of interpolation methods that are used in resampling process before the vibration signal analysis by the change of the motor sped. The motor speed is measured by the tachometer. Tachometer produces one pulse per rotation. We determined resampling time by angle interpolation. To estimate the sample values, we used various interpolation technique. This paper estimated the discrete signal through the linear, quaratic, and cubic interpolation. We proposed the optimum interpolration method by comparing MSE(Mean Squre Error) and calculation amount.

베타카로틴 함유 마이크로에멀젼의 제조 및 물리화학적 특성 평가

곽은선,이종화,박목순,이계원,지웅길 충남대학교 약학대학 의약품개발연구소 2000 藥學論文集 Vol.16 No.-

The o/w microemulsions containing β-carotene were made from 3 or 5% w/w oil(soybean oil, cottonseed oil and isopropyl myristate) and 15, 20 or 25% w/w nonionic surfactant (Cremophor EL, Cremophor RH 40 and Brij 97/Pluronic F-68(2:1 w/w). They are characterized by particle size distribution, surface tension and viscosity. Also, stability study was done by antioxidant, long-term storage for 6 months.

무지개 松魚의 遺傳 育種學的 硏究 : Ⅳ.血淸成分 水準의 年中 變化 Ⅳ.Annual Changes of Serum Components Levels

朴弘陽,尹鐘萬,金桂雄 건국대학교 동물자원연구센터 1991 動物資源硏究誌 Vol.16 No.-

본 연구는 무지개 松魚 암컷 3년생 120마리에 대하여 1989년 3월부터 1990년 2월까지 계절 및 人工産卵前後에 따른 血淸成分 含量 水準을 측정하였고, 각 血淸 成分間의 상관관계를 조사하였다. 장차 무지개 松魚의 繁殖效率 增進에 필요한 遺傳育種學的 基礎 資料를 얻기 위하여 실시되었다. 본 연구에서 얻어진 결과를 요약하면 다음과 같다. 1) 血淸中 albumin, calcium, glucose, total protein, alkalin phosphatase, SGOT 및 phosphorus의 함량은 産卵期中에 높은 수준이었으나, cholesterol, creatinine 및 triglycerides의 含量은 卵黃形成期中에 비교적 높은 수준을 유지 하였다. 2) 人工産卵展, 産卵後 및 過熟時期에 따른 血淸中 albumin, calcium, cholesterol, creatinine, total protein, triglycerides, alkaline phosphatase 및 phosphorus의 含量은 人工産卵前에 비교적 높은 수준을 유지한 반면에, BUN, glucose, SGOT 및 SGPT의 含量은 過熟時期에 높은 수준이었다. 그리고 A/G 比率은 非産卵期인 6월, 7월 및 8월에 最高水準을 유지하다가 産卵時期直前부터 감소하여 산란시기 동안에 낮은 수준으로 계속 유지되었다. 3) 産卵期中 albumin수준과 calcium(r=-0.793)간에는 부(-)의 상관이었으나, 그 밖의 다른 성분간에는 有意性이 인정되는 정(+)의 상관이 존재하였다. BUN 含量水準과 alkaline phosphatase(r=0.790), SGOT(r=0.881) 및 SGPT(r=0.902)와는 正(+)의 高度相關이 존재하였다. Glucose수준과 모든 다른 성분간에는 負(-)의 相關關係였으마, cholesterol수준과 그 밖의 다른 성분간에는 正(+)의 相關이 존재하였다. Glucose수준과 total protein(r=0.856), triglycerides(r=0.973), alkaline phosphatase(r=0.738), SGOT(r=0.711) 및 SGPT(r=0.738), 및 SGPT(r=0.657)間에는 正(+)의 高度相關을 보였으며, creatinine 수준과 total protein(r=0.672)에도 正(+)의 상관관계가 존재하였다. Total protein과 triglycerides(r=0.911)와는 正(+)의 高度相關이었으며, alkaline phosphatase 水準과 SGOT(r=0.936) 및 SGPT(r=0.926)間은 正(+)의 高度相關關係가 있다. 또한 SGOT와 SGPT(r=0.995)와는 매우 높은 정(+)의 상관관계가 존재하였다. 4) 産卵期中 호르몬과 血淸成分間의 상관관계에 있어서 血淸中 LH 濃度와 BUN(r=0.747)과는 유의한 負(-)의 相關이었으나, creatinine(r=0.887) 및 total protein(r=0.688)과는 正(+)의 高度相關이 존재하였다. FSH濃度와 creatinine(r=0.831) 및 total protein(r=0.709)간에는 正(+)의 상관관계가 있었다. Estradion-17β와 creatinine(r=0.899), total protein(r=0.899), total protein(r=0.859) 및 trigpycerides(r=0.673)간에 비교적 높은 正(+)의 상관이었으나, progesterone 濃度과 BUN(r=-0.606)간에는 負(-)의 상관관계가 존재하였다. This study was carried out to investigate serum components levels(12 components) obtained from 120 of 3-year-old female rainbow trout(Oncorhynchus mykiss). All data were collected and analysed monthly from March in 1989 to February in 1990. Serum protein components were assayed by blood analyzer. The results obtained in this study were as follows; 1. The contents of serum albumin ,calcium, glucose, total protein, alkalkine phosphatase, SGOT, and phosphorus increased during spawning period, but those of serum cholesterol, creatinine, and triglycerides maintained relatively high levels during vitellogenetic period. 2. The contents of serum albumin, calcium, cholesterol, creatinine, total protein, triglycerides, alkaline phosphatase and phosphorus prior to handstripping were relatively high, while those of serum BUN, glucose, SGOT and SGPT were high in over-ripe stage. 3. The correlation between serum albumin and calcium during correlations of albumin and other contents were significantly positive. Those of serum BUN with alkaline phosphatase(r=0.790), SGOT(r=0.881) and SGPT(r=0.902) were highly positive. The content of calcium was highly correlated with various serum contents, and that of cholesterol was a signigicantly correlated with other serum contents. The correlations of serum glucose with total protein(r=0.856), triglycerides(r=0.973), alkaline phosphatase(r=0.738), SGOT(r=0.711) and SGPT(r=0.657) were significantly high. The correlation coefficients between creatinine and total protein, between total protein and triglycerides, and between SGOT and SGPT were significantly high. In addition, those of serum alkaline phosphatase with SGOT and SGPT were also significantly high. 4. The correlation of serum LH with BUN during spawning period was highly negative(r=-0.793), while the correlations of LH with creatinie and total protein were high(r=0.887 and 0.688, respectively). Similarly, the relationships of serum FSH with creatinine(r=0.831) and total protein(r=0.709) were significantly highly positive. The concentration of estradiol-17βwas highly correlated with creatinie, total protein, and triglycerides. But the relation of serum progesterone with BUM was significantly negative(r=-0.606).

하악골에 발생된 Low grade 골육종:증례보고

조현이,정종철,김호성,최재욱,성대경,서지훈,김성범,이계혁 大韓顎顔面成形再建外科學會 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.1

Osteosarcoma is a primary malignant tumor arising most often in the long bone, but rare in jaw bone. Especially osteogenic sarcoma of the mandible is a rare tumor, comprising less than 0.5% of all head and neck tumors. Osteosarcoma occurs cheifly in young persons, and presenting very survival rates. Histopathologically this tumor can be classified three types, osteoblastic, fibroblastic, chondroblastic and classified from low grade to high grade by anaplasia or mitosis of the tumor cells. Sometimes, the exact diagnosis of osteosarcoma is difficult especially in low grade osteosarcoma, even if clinical or radiographical findings suggest to osteosarcoma. So suspcious to malignant bone tumor in clinical or radiological findings, biopsy should be taked from deep portion and multiple area, and sharing the patient history and radiographs with pathologist will assist in the development of the diagnosis. We report a case of low grade osteosarcoma on the mandible initially difficulty in accurate diagnosis. The patient visited our hospital for routine dental treatment but radiographic findings displayed ill-defined radiolucency with osteoid formation on the mandible. Final diagnosis was difficulty in initial biopsy but subsequent biopsy taked from deep portion presented infiltrative growth and mitosis of the tumor cell in some area with small osteoid bone formation, so we could reach final diagnosis as low grade sarcoma. We treated this patient with bloc resection of the mandible and immediate reconstruction with iliac corticocancellous block.