Hormone Use is Associated with Lymphovascular Invasion in Breast Cancer

Loof-Johanson, Margaretha,Brudin, Lars,Sundquist, Marie,Rudebeck, Carl Edvard Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3

Background: Risk of developing breast cancer increases with short breastfeeding and the use of hormones. The prognosis of breast cancer is better if the tumours are hormone receptor positive. Since breast feeding affects estrogen and progesterone receptors, we wanted to investigate how such reproductive factors as breastfeeding and the use of hormones interact with known prognostic markers and specific tumour characteristics in women with breast cancer. Materials and Methods: A total of 250 women treated for breast cancer from a larger cohort completed a questionnaire on breastfeeding, number and age at births and use of hormones. A logistic regression analysis was made to search for connections between known prognostic markers on the one hand (type of cancer, grade, tumor size, estrogen receptor and progesterone receptor, lymphovascular invasion and DNA-ploidy) and reproductive data, breastfeeding, and hormone use on the other. Results and Conclusions: Hormone use, but not breastfeeding, was significantly associated, also on multivariate analysis, with the prognostic variable lymphovascular invasion, connected to a worse prognosis. No other hormone use or breast feeding correlations with prognostic variables were found.

COOPERATION IN BUSINESS NETWORKS

(Kent Eriksson),(Jan Johanson) 한국국제경영학회 1999 한국국제경영학회 국제학술 발표대회 Vol.1999 No.-

Recent Insights from the International Common-Cause Failure Data Exchange Project

Albert Kreuser,Gunnar Johanson 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.2

Common-cause failure (CCF) events can significantly impact the availability of safety systems of nuclear power plants. For this reason, the International Common Cause Data Exchange (ICDE) project was initiated by several countries in 1994. Since 1997 it has been operated within the Organisation for Economic Co-operation and Development (OECD)/ Nuclear Energy Agency (NEA) framework and has successfully been operated over six consecutive terms (the current term being 2015-2017). The ICDE project allows multiple countries to collaborate and exchange CCF data to enhance the quality of risk analyses, which include CCF modeling. As CCF events are typically rare, most countries do not experience enough CCF events to perform meaningful analyses. Data combined from several countries, however, have yielded sufficient data for more rigorous analyses. The ICDE project has meanwhile published 11 reports on the collection and analysis of CCF events of specific component types (centrifugal pumps, emergency diesel generators, motor operated valves, safety and relief valves, check valves, circuit breakers, level measurement, control rod drive assemblies, and heat exchangers) and two topical reports. This paper presents recent activities and lessons learnt from the data collection and the results of topical analysis on emergency diesel generator CCF impacting entire exposed population.

Introduction: Comparative Performance Management and Accountability in the Age of Austerity

Grossi, Giuseppe,Hansen, Morten Balle,Johanson, Jan-Erik,Vakkuri, Jarmo,Moon, M. Jae Taylor Francis 2016 PUBLIC PERFORMANCE & MANAGEMENT REVIEW Vol.39 No.3

Institutional work and accountability in public–private partnerships

Ville-Pekka Sorsa,Jan-Erik Johanson 한국행정학회 2014 International Review of Public Administration Vol.19 No.2

The large-scale emergence of public–private partnerships (PPPs) has drawn attention to the mechanisms of accountability in PPPs. However, there has been little research yet on how the institutional logics of the mechanisms are instituted, and there is stilllittle knowledge on the role of accountability in the governance of PPPs. The purposeof this article is to develop a theoretical framework for studying the institutional logics of accountability in PPPs by including institutional work projects in an analysis. The theoretical framework is applied in a single case analysis of the Finnish public–private pension system TyEL. The case study reveals accountability gaps and changes previous understanding of the role of public accountability in governance of PPPs.

THE ROLE OF ORGANIZATIONAL AGILITY IN DIGITAL INNOVATION: A RELATIONAL PERSPECTIVE

Sabrina Thornton,Desir?e Holm,Martin Johanson,David S?rhammar 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07

The unbounded nature of digital innovation requires innovating firms to be agile in the way they manage the processes, governance and outcomes in order to sense and seize the market directly and timely. This study adopts an inter-organizational approach and asks to what extent and in what way does organizational agility impact on innovation performance? This perspective underscores the interdependencies between collaborating partners, which creates a relationship regulating system of workflow to drive value creation in the process of innovation. While the literature has offered a broad conceptual argument for organizational agility in the context of digital innovation, the mechanisms through which value is transformed in the innovation process is still unclear. We contend that an agile innovation process stands on four main cornerstones: (1) joint strategic planning, (2) joint problem solving, (3) joint improvisation and (4) community (market) sensing. The empirical research is set in the video game industry, which is in a largely digitalized and borderless business environment. The data was collected through an interviewer-administered questionnaire. The sampling frame is based on a Swedish trade association database. Usable sample is 113. We performed structural equation modelling to test the hypothesized model, including main and moderation effects, using Mplus. The findings show that while only improvisation has a significantly positive effect on innovation performance, the role of strategic planning and problem solving between two collaborating partners remains unclear. For example, strategic planning has shown to be a negative influence in our empirical research. Problem solving has no effect on innovation performance, but it interacts with community sensing and subsequently facilitates innovation outcome. This highlights the importance of community sensing, which could offer rich, crucial knowledge and resources for problem solving that proves to be effective. The results provide further theoretical arguments for understanding organizational agility and digital innovation, but also raise further questions for future research.

해외시장 진입에서의 비즈니스 네트워크의 학습과 몰입 -삼성전자의 영국시장 진입

이중우 ( Joong Woo Lee ),전용욱 ( Yong Wook Jun,Jan Johanson ) 韓國國際經營學會 2006 國際經營硏究 Vol.17 No.3

본 연구는 후발진입 기업의 시장진입과정을 탐색하였다. 본 연구에서는 해외시장진입과 국제화의 역동적인 비즈니스 네트워크 모델을 제시한다. 기존의 국제화 과정이론과 비교했을 때 공급자와 소비자 기업들 사이의 비즈니스 관계는 한쪽 측면의 경험학습과 해외시장 몰입에 초점을 두고 있다. 이러한 시각에서 벗어나 본 연구는 양측의 학습과 몰입에 초점을 맞추고 있다. 이는 또한 기업의 비즈니스 관계가 발전될 때 폭넓은 비즈니스 네트워크속에서 수반되어지는 것을 가정한다. 본 연구는 삼성전자의 영국시장 진입에 대한 하나의 심층적인 사례연구를 제공한다. 사례연구는 학습과 몰입의 세 가지 영역: 시장의 지리적인 위치확보, 시장으로 몰입된 조직기능들과 시장에 공급된 제품의 중요성과 제품수를 고려하였다. 그 세 가지 영역의 발전에서 비즈니스 관계의 역할 또한 보여준다. 사례에서는 삼성의 성공적이며 빠른 영국시장진입의 학습과 특히 비즈니스 네트워크 학습의 중요한 역할을 증명하였다. 그리고 점진적인 몰입도의 증가가 나타났다. This study explores the market entry process of a latecomer firm. It outlines a dynamic business-network model of foreign market entry and internationalization. Compared with received internationalization process theory it moves focus from unilateral experiential learning and foreign market commitment to bilateral learning and commitments in business relationships between supplier and customer firms. It also assumes that the firm, when developing a business relationship, becomes involved in a wider business network. The study presents an in-depth case study of Samsung Electronics` entry into the British market. The case study considers three areas of learning and commitment: geographical cover of the market, organization functions committed to the market and number and importance of products supplied in the market. It shows also the role of business relationships in the development of the three areas. The case demonstrates that in Samsung`s successful, rapid British market entry learning, and in particular, business network learning, plays an important role. It also indicates that commitments are gradual.