http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Time-varying Arbitrage Efficacy
( Jingzhi Chen ),( Yongcheol Shin ),( Huamao Wang ) 한국금융연구원 2022 금융연구 working paper Vol.2022 No.10
Arbitrageurs utilise leverage to capitalise on arbitrage opportunities. If an adverse shock is large enough to make leverage constraint binding, arbitrage activities become ineffective as they are forced to deleverage. As a main contribution we propose a novel measure of time-varying arbitrage efficacy that can identify the periods when arbitrage activities become ineffective. The arbitrage efficacy is shown to be a significant predictor of the financial market volatility and instability, more prominent during ineffective arbitrage periods that coincide with market turmoil. This suggests that the arbitrage efficacy can serve as an indicator of the marketwide downside risk.
Jingzhi Li,Ruiqi Feng,Zhihui Wen,Aili Zhang 한국생물공학회 2017 Biotechnology and Bioprocess Engineering Vol.22 No.4
To investigate effects of different pyruvate decarboxylases on isobutanol titers in Saccharomyces cerevisiae, single-gene deletion of the three PDCs genes encoding pyruvate decarboxylases were constructed in this study. In addition, we over-expressed Ilv2, which catalyzed the first step in the valine synthetic pathway, and Bat2, which was the cytoplasmic branched-chain amino-acid aminotransferase that catalyzed L-valine to 2-ketoisovalerate, to increase isobutanol production in the genetically modified strains. Our results showed that knockout of PDC5 were one of the main factors among the three PDC genes for improving isobutanol titers in S. cerevisiae. Additionally, we found that deletion of PDC5 in strain carrying overexpressed ILV2 and ARO10 resulted in 8-fold higher isobutanol productivity as compared to the control strain in micro-aerobic fermentations. Our results also suggested that engineered strain pdc5ΔpILV2 pARO10 generated lower ethanol titers and higher acetate acid titers than the control strain, while the growth rate and glucose consumption rate of engineered strain pdc5ΔpILV2 pARO10 were slightly lower than that of the control strain. Meanwhile, the biomass concentration of pdc5ΔpILV2 pARO10 decreased dramatically than that of the control strain.
Knockdown of RBBP6 enhances radiosensitivity of gastric cancer cells through p53 pathway
Bi Meng,Sun Jingzhi,Wang Fengtong,Li Shenchi 대한독성 유전단백체 학회 2022 Molecular & cellular toxicology Vol.18 No.4
Background Radiotherapy is regarded as commonly standard-of-care for the treatment of patients with gastric cancer. However, the resistance to radiotherapy impedes the efficiency of the therapy. Retinoblastoma-binding protein 6 (RBBP6), an independent prognostic factor of gastric cancer, contributed to the cancer progression. RBBP6 was associated with chemoresistance and radioresistance of colorectal cancer. However, the effect of RBBP6 on radiosensitivity of gastric cancer has not been investigated yet. Objective To investigate the effect of RBBP6 on radiosensitivity of gastric cancer. Results Knockdown of RBBP6 decreased the cell viability of gastric cancer cells after the irradiation. The cell proliferation of irradiation-treated gastric cancer cells was also suppressed by silence of RBBP6. Moreover, interference of RBBP6 promoted cell apoptosis of gastric cancer cells, and significantly aggravated irradiation-induced cell apoptosis ( p < 0.01). Protein expression of p21 and p53 in irradiation-treated gastric cancer cells was significantly increased by knockdown of RBBP6 ( p < 0.01). Silence of RBBP6 enhanced the in vivo inhibitory effect of irradiation on gastric cancer growth. Conclusion RBBP6 silence was considered to be a potential sensitizer for the radiotherapy of gastric cancer through activation of p53 signaling.
Yuejie Xie,Zhi-Fei He,Jingzhi Lv,En Zhang,Hong-Jun Li 한국축산식품학회 2016 한국축산식품학회지 Vol.36 No.6
The aim of this study was to explore the volatile compounds of hind leg, foreleg, abdomen and Longissimus dorsi in both male and female Hyla rabbit meat by solid phase microextraction tandem with gas chromatography mass spectrometry, and to seek out the key odorants via calculating the odor activity value and principal component analysis. Cluster analysis is used to study the flavor pattern differences in four edible parts. Sixty three volatile compounds were detected, including 23 aldehydes, 4 alcohols, 5 ketones, 11 esters, 5 aromatics, 8 acids and 7 hydrocarbons. Among them, 6 aldehydes and 3 acids were identified as the potential key odorants according to the ratio of concentration and threshold. The contents of volatile compounds in male Hyla rabbit meat were significantly higher than those in female one (p<0.05). The results of principal component analysis showed that the first two principal component cumulative variance contributions reach 87.69%; Hexanal, octanal, 2-nonenal, 2-decenal and decanal were regard as the key odorants of Hyla rabbit meat by combining odor activity value and principal component analysis. Therefore volatile compounds of rabbit meat can be effectively characterized. Cluster analysis indicated that volatile chemical compounds of Longissimus dorsi were significantly different from other three parts, which provide reliable information for rabbit processing industry and for possible future sale.
Xue, Shan,He, Zhifei,Lu, Jingzhi,Tao, Xiaoqi,Zheng, Li,Xie, Yuejie,Xiao, Xia,Peng, Rong,Li, Hongjun Korean Society for Food Science of Animal Resource 2015 한국축산식품학회지 Vol.35 No.1
The changes in fatty acid composition of total intramuscular lipid and phospholipids were investigated in the longissimus dorsi, left-hind leg muscle, and abdominal muscle of male Ira rabbits. Changes were monitored at 35, 45, 60, 75, and 90 d. Analysis using gas chromatography identified 21 types of fatty acids. Results showed that the intramuscular lipid increased and the intramuscular phospholipids (total intramuscular lipid %) decreased in all muscles with increasing age (p<0.05). An abundant amount of unsaturated fatty acids, especially polyunsaturated fatty acids, was distributed in male Ira rabbits at different ages and muscles. Palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), and arachidonic acid (C20:4) were the major fatty acids, which account to the dynamic changes of the n-6/n-3 value in Ira rabbit meat.