A Cognitive Grammar Approach to the Antipassive Construction in English

Jing Ying Li,Kyu-Hong Hwang 한국언어과학회 2021 언어과학 Vol.28 No.4

An Embodied Cognition Approach to the Countability of Nouns in English

Jing Ying Li,황규홍 한국언어과학회 2022 언어과학 Vol.29 No.2

This paper reexamines the countability of English nouns based on the notion of embodied cognition. It is argued that both the prototype approach and the dynamic construal approach exemplify the embodiment view in terms of categorization in which the former can serve as the conceptual basis whereas the latter can function as a psychological basis. From a prototype approach, there are middle places between count and non-count nouns, so the boundary between the two subcategories is fuzzy. From a dynamic construal approach, it is suggested that there is no stable category and that we have only the contextual count nouns and non-count nouns. It is also proposed that nouns in this context tend to undergo a process of decategorization from the original categories and be recategorized into ad-hoc categories. The variability and flexibility of nouns as the semantic unit exhibit the contextuality and dynamics of human conceptualization by adopting the means of metaphor or metonymy. In addition, the interconversion of countability of nouns is also influenced by the domain of instantiation of the nouns, maximal and immediate scopes of human visual domains, and specificity and schematicity of the nouns.

Antiblurry Dejitter Image Stabilization Method of Fuzzy Video for Driving Recorders

( Jing-ying Xiong ),( Ming Dai ),( Chun-lei Zhao ),( Ruo-qiu Wang ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.6

Video images captured by vehicle cameras often contain blurry or dithering frames due to inadvertent motion from bumps in the road or by insufficient illumination during the morning or evening, which greatly reduces the perception of objects expression and recognition from the records. Therefore, a real-time electronic stabilization method to correct fuzzy video from driving recorders has been proposed. In the first stage of feature detection, a coarse-to-fine inspection policy and a scale nonlinear diffusion filter are proposed to provide more accurate keypoints. Second, a new antiblurry binary descriptor and a feature point selection strategy for unintentional estimation are proposed, which brought more discriminative power. In addition, a new evaluation criterion for affine region detectors is presented based on the percentage interval of repeatability. The experiments show that the proposed method exhibits improvement in detecting blurry corner points. Moreover, it improves the performance of the algorithm and guarantees high processing speed at the same time.

Prototypicality and Markedness in the English Passive

Jing Ying Li,Kyu-Hong Hwang 한국언어과학회 2020 언어과학 Vol.27 No.1

A Schema Category Theory-based Analysis of the Get+V-en Construction

Jing Ying Li,Kyu-Hong Hwang 한국언어과학회 2020 언어과학 Vol.27 No.3

The purpose of this paper is to investigate English Get+V-en construction on the basis of the schema category theory proposed by Langacker(1987, 2000, 2009). Contrary to the passive or non-passive attribution of the Get+V-en construction, this study proposes that the Get+V-en construction is a fuzzy set that designates the gradient feature and its schema instantiates itself by abstracting the general features of the prototype and its extension. The passivization of the Get+V-en construction ranks in three layers, where the central Get-passive (agentful or agentless) serves as the prototype at the first layer. The psychological, reflexive, and reciprocal Get-passives are regarded as semi-Get-passives, functioning as instantiation one at the second layer. Both the adjectival and the formulaic Get-passives can be construed as pseudo Get-passives, representing instantiation two at the third level. The component get shows gradient features from lexical to copular, and V-en demonstrates a dynamic change being either verbal or adjectival in different variants of the Get+V-en construction. The schematic characterization of the central Get-passive can be summarized as follows: Get is a ‘semi-grammaticalized’ word that lies in between lexical verbs and genuine auxiliaries; The Get-passive is generally compatible with dynamic verbs with a causative meaning denoting a resultative state; It is subject-oriented and characteristically used in clauses involving adversity or benefit.

Overexpression of microRNA-612 Restrains the Growth, Invasion, and Tumorigenesis of Melanoma Cells by Targeting Espin

Ying Zhu,Hao-liang Zhang,Qi-ying Wang,Min-jing Chen,Lin-bo Liu 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.2

microRNA (miR)-612 shows anticancer activity in several types of cancers, yet its function in melanoma is still unclear. This study was undertaken to investigate the expression of miR-612 and its biological relevance in melanoma cell growth, invasion, and tumorigenesis. The expression and prognostic significance of miR-612 in melanoma were examined. The effects of miR-612 overexpression on cell proliferation, colony formation, tumorigenesis, and invasion were determined. Rescue experiments were conducted to identify the functional target gene(s) of miR-612. miR-612 was significantly downregulated in melanoma tissues compared to adjacent normal tissues. Low miR-612 expression was significantly associated with melanoma thickness, lymph node metastasis, and shorter overall, and disease-free survival of patients. Overexpression of miR-612 significantly decreased cell proliferation, colony formation, and invasion of SK-MEL-28 and A375 melanoma cells. In vivo tumorigenic studies confirmed that miR-612 overexpression retarded the growth of A375 xenograft tumors, which was coupled with a decline in the percentage of Ki-67-positive proliferating cells. Mechanistically, miR-612 targeted Espin in melanoma cells. Overexpression of Espin counteracted the suppressive effects of miR-612 on melanoma cell proliferation, invasion, and tumorigenesis. A significant inverse correlation (r = -0.376, P = 0.018) was observed between miR-612 and Espin protein expression in melanoma tissues. In addition, overexpression of miR-612 and knockdown of Espin significantly increased the sensitivity of melanoma cells to doxorubicin. Collectively, miR-612 suppresses the aggressive phenotype of melanoma cells through downregulation of Espin. Delivery of miR-612 may represent a novel therapeutic strategy against melanoma.

MiR-188-5p regulates the proliferation and differentiation of goat skeletal muscle satellite cells by targeting calcium/calmodulin dependent protein kinase II beta

Jing Jing,Sihuan Zhang,Jinbo Wei,Yuhang Yang,Qi Zheng,Cuiyun Zhu,Shuang Li,Hongguo Cao,Fugui Fang,Yong Liu,Ying-hui Ling Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.12

Objective: The aim of this study was to reveal the role and regulatory mechanism of miR-188-5p in the proliferation and differentiation of goat muscle satellite cells. Methods: Goat skeletal muscle satellite cells isolated in the pre-laboratory were used as the test material. First, the expression of miR-188-5p in goat muscle tissues at different developmental stages was detected by quantitative reverse transcription polymerase chain reaction (qRT-PCR). In addition, miR-188-5p was transfected into goat skeletal muscle satellite cells by constructing mimics and inhibitors of miR-188-5p, respectively. The changes of differentiation marker gene expression were detected by qPCR method. Results: It was highly expressed in adult goat latissimus dorsi and leg muscles, goat fetal skeletal muscle, and at the differentiation stage of muscle satellite cells. Overexpression and interference of miR-188-5p showed that miR-188-5p inhibited the proliferation and promoted the differentiation of goat muscle satellite cells. Target gene prediction and dual luciferase assays showed that miR-188-5p could target the 3'untranslated region of the calcium/calmodulin dependent protein kinase II beta (CAMK2B) gene and inhibit luciferase activity. Further functional studies revealed that CAMK2B promoted the proliferation and inhibited the differentiation of goat muscle satellite cells, whereas si-CAMK2B restored the function of miR-188-5p inhibitor. Conclusion: These results suggest that miR-188-5p inhibits the proliferation and promotes the differentiation of goat muscle satellite cells by targeting CAMK2B. This study will provide a theoretical reference for future studies on the molecular mechanisms of skeletal muscle development in goats.

A hemoglobin-based oxygen-carrying biomimetic nanosystem for enhanced chemo-phototherapy and hypoxia alleviation of hepatocellular carcinoma

Jing-Qing Le,Fang Yang,Xun-Huan Song,Ke-Ke Feng,Ling-Wu Tong,Meng-Die Yin,Wen-Zhong Zhang,Ying-Qi Lin,Hui Wu,Jing-Wei Shao 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.123 No.-

Tumor microenvironment is characterized by low pH, high reactive oxygen species and hypoxia, whichprovides a suitable environment for cancer growth. The hypoxia not only elevates tumor angiogenesisand metastasis, but also is responsible for the development of treatment resistance, which graduallybecomes a significant impediment for cancer therapy. Therefore, we developed a biomimetic nanosystemcontaining hemoglobin extracted from red blood cells, chemotherapy drug sorafenib, sensitizer ursolicacid and photosensitizer indocyanine green for enhanced chemo-photo combination therapy of hepatocellularcarcinoma, which could not only enhance the chemotherapy effect of sorafenib bowing to thesensitizing effect of ursolic acid, but also achieved synergetic phototherapy in virtue of indocyaninegreen. Besides, the nanoparticles could effectively delivery exogenous oxygen to tumor site and amelioratethe tumor hypoxic environment with the assistance of hemoglobin. The dual-sensitization drugdelivery system was expected to effectively reduce the resistance of traditional treatment methodsagainst tumor hypoxia, providing a novel prospect for the synergistic hepatocellular carcinomatreatment.

A Nonlinear Controller Design Based on the Interpolation Chart

Ying-Jing Shi,Guang-Fu Ma 제어로봇시스템학회 2006 제어로봇시스템학회 국제학술대회 논문집 Vol.2006 No.10

Moth-Flame Optimization-Based Maximum Power Point Tracking for Photovoltaic Systems Under Partial Shading Conditions

Ji-Ying Shi,Deng-Yu Zhang,Fei Xue,Ya-Jing Li,Wen Qiao,Wen-Jing Yang,Yi-Ming Xu,Ting Yang 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.5

This paper presents a moth-flame optimization (MFO)-based maximum power point tracking (MPPT) method for photovoltaic (PV) systems. The MFO algorithm is a new optimization method that exhibits satisfactory performance in terms of exploration, exploitation, local optima avoidance, and convergence. Therefore, the MFO algorithm is quite suitable for solving multiple peaks of PV systems under partial shading conditions (PSCs). The proposed MFO-MPPT is compared with four MPPT algorithms, namely the perturb and observe (P&O)-MPPT, incremental conductance (INC)-MPPT, particle swarm optimization (PSO)-MPPT and whale optimization algorithm (WOA)-MPPT. Simulation and experiment results demonstrate that the proposed algorithm can extract the global maximum power point (MPP) with greater tracking speed and accuracy under various conditions.