한방 이화주의 미백 및 피부 주름 개선 효과

이상진(Sang-Jin Lee),권이영(Yi-Young Kwon),조성원(Sung-Won Cho),권희숙(Hee-Suk Kwon),신우창(Woo-Chang Shin) 한국식품영양과학회 2013 한국식품영양과학회지 Vol.42 No.4

본 연구에서는 한방이화주의 피부 생리기능 활성을 알아보기 위해 70% EtOH 추출물의 피부 미백, 주름 개선 및 항염증 효과를 조사하였다. HEE은 tyrosinase 활성 억제 및 tyrosine을 기질로 melanin이 형성되는 pathway에 관여하는 주요한 인자인 TRP-1과 TRP-2를 저해하는 작용 기전을 통해 피부 색소침착의 주요 원인 물질인 melanin 생합성을 농도 의존적으로 저해하는 것을 확인하였다. HEE은 피부진피 내 피부 탄력을 유지하는 elastin을 분해하는 효소인 elastase의 활성을 저해하였고, 피부의 keratinocyte가 생성분비하는 MMP-2와 MMP-9의 단백질 발현과 proteolytic 활성을 억제하여 노화에 따른 피부 주름 생성 억제할 수 있는 가능성을 확인하였다. 또한 세포 독성 없이 LPS에 의해 유도된 염증 반응을 50% 저해하는 HEE의 농도(IC50)는 24.9 μg/mL이며, 50 μg/mL 농도로 처리하였을 때 염증 반응 저해 효과가 70%로 높은 효과를 가지는 것을 확인하였다. 이상의 결과를 종합하면 HEE의 피부 미백, 주름 개선 및 항염증에 우수한 효과를 나타내고 있으므로 기능성 화장품의 주요한 소재로 이용 가치가 높을 것으로 사료된다. Extrinsic skin aging is characterized by the loss of skin tone and resilience, irregular pigmentation, and deep wrinkles. The aim of this study was to investigate the effects of Ehwa Makgeolli containing oriental herbs (Glycyrrhiza uralensis Fisch., Lycium chinense MILL., Morus alba L., and Saururus chinensis Baill) on skin whitening and wrinkling in human skin cells. We prepared Makgeolli extracts (HEE) with 70% ethanol. HEE significantly inhibited in vitro mushroom tyrosinase activity and reduced the cellular and secreted melanin content of mouse melanoma melanocytes (B16F1 cells). HEE down-regulated the protein expression of tyrosinase related protein (TRP)-1/-2, a key player in melanogenesis. Treatment with HEE in human keratinoctyes (HaCaT cells) inhibited the proteolytic activities of matrix metalloproteinase (MMP)-2/-9 in a dose-dependent manner and dramatically reduced the expression of MMP-2/-9. In addition, HEE attenuated lipopolysaccharide (LPS)- induced nitric oxide production in murine macrophages (RAW264.7 cells). These results indicate that HEE may be a great cosmeceutical ingredient for its whitening, anti-wrinkle, and anti-inflammatory effects.

진도 북춤과 밀양 오북춤의 비교연구

박진희 韓國舞踊敎育學會 1998 韓國舞踊敎育學會誌 Vol.9 No.2

This study analyses the comparison of the southern west Jin-Do drum dance and the southern east Mil-yang give drum dance which has its own locational distinction and developmental procedure. The origin of Jin-do drum dance comes from the last act of the theatrical dance Jin-Do Dasire during the three nations period. It had formed as a recreational role but had been influxed into field hymn to enhance the field labor by following the drumbeats. Mil-Yang five drum dance had formed during the three provincial period as a ritual ceremony for the supplication of the harvest. Also it had formed as a recovery of the healthy life by dissolving the repression from the ruler by beating the drum. Both of these drum dances have similarities but have different origin motivations. In the form of Jin-Do drum dance, there are variety of patterns, subtle rhythms and high technical skilled movements, in which artistic value is hidden. On the other hand, in the Mil-yang five drum dance there are simple movement patterns with one count of beating, but the movements possess natural simplicity and dynamics. Performing Jin-Do dance, a drum is carried in the same way like so called Jang-Go. Instead of two drum sticks are used in Jin-do dance, in Mil-Yang dance there is only one stick is being used. These instrumental differences indicate that the Jin-Do dance reflects the social environment. In Jin-do Drum dance, there is no limitation not only of the number of members and the number of drums but also no differentiation of the gender as well. Contrary in Mil-Yang five Drum dance only men can attend, and there is storing limitation of the playing participants. However, besides the differences, two dances share some similarities. praying the nature's harvest and reflects the simplicity of peasant's movements. Beating drum, farmers threw away their labor repression nad sublimating to the tool of play.

2차병원에서의 소아과 환자의 응급실 및 외래 이용에 관한 연구

김진희,배진호,전진호,문정웅 인제대학교 2006 仁濟醫學 Vol.27 No.-

Objectives : To analyze the characteristics of the pediatric patients who visited the emergency room and outpatient department of secondary hospital in order to properly guide pediatric patients to use emergency room and raise the efficiency Methods : The authors investigated and analyzed sex, age, visit day, visit time, length of stay, hospitalization and diagnostic entities of the pediatric patients who visited the emergency room and outpatient department of Wallace Memorial Baptist Hospital from January 2003 to December 2005 in a retroactive approach with their medical records. Results : For the three years, the number of total patients who visited the emergency room was 56,051 and among them, the number of pediatric patients was 7,490 (13.4%). The age group of 1 to 2 years was the largest with 2,488 (33.2%). The male to female ratio was 1.34:1. Sunday was the day of the week that the largest number of patienst visited with 2,375 (31.7%) and nearly half (48.4%) of the patients visited the emergency room during the weekend. The time when the most patient visited the emergency room was between 8 pm to 12 am. Regarding the length of stay, the highest number of patients (65.0%) stayed in the emergency room for on hour or less, and the average length of visit was 1.5 hours, which was rather short. Most patients (68.8%) left the hospital after taking simple physical examination and procedure(prescription). The most frequent diagnoses for the pediatric patients who visited the emergency room were acute pharyngitis (26.0%), acute gastroenteritis (20.7%), fever (6.6%). During the same period, the total number of pediatric patients who visited the outpatient department was 125,513. The age group of 3 to 5 was the largest with 36,041 (28.7%). The male to female ratio was 1.34:1. 6.0% of total outpatients required treatment in a hospital. Most frequent diagnoses of the outpatients were asthma (24.4%), pneumonia (12.0%), vaccination (8.7%), febrile convulsion (8.4%), acute pharyngitis (6.6%), acute gastroenteritis (5.8%). Conclusion : It is considered that a large number of pediatric patients still have used emergency room for treatment of simple and mild diseases instead of visiting outpatient department and/or primary hospital. Thus further efforts are required to properly guide pediatric patients to use emergency room and to raise the efficiency of their use.

급성충수돌기염으로 발현된 방선균증 2예

조진원,송진영,김창억,민영훈,최창순,우흥정,현인규,김종현,유기철,채승완,손진희 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

The Actinomyces species are normal flora of oral cavity and upper intestine characterized as gram-positive, non-spore-forming anaerobic or mjcroaerophilic rods. Actinomycosis is a chronic suppurative and granulomatous disease characterized by abscess, sinus, abundant granulation and mass. The appendix is the commonly involved site among abdominal actinomycosis. Abdominal actinomycosis is often difficult to diagnose before operation because of no reliable clinical features and infrequency of the disease. We report two cases of abdominal actinomycosis which were manifested as acute appendicitis. Those were detected Incidentally tv the pathologist after routine appendectomy. Both patients were successfully treated with appendectomy followed by proper antibiotics use.

대학 e-러닝의 학습자 특성 및 교수자 특성 요인에 대한 한국과 중국의 인식도 차이

김희정(Hee jung Kim),장몽로(Zhang Meng Lu),조숙진(Sook jin Cho),이석준(Seog iun Lee) 건국대학교 경제경영연구소 2013 商經硏究 Vol.38 No.2

전통적인 면대면 교수-학습 환경에 대한 대안으로 인터넷을 통해 학습자의 학습 환경을 촉진하고 지원하며, 학습자가 자기 주도적(Self-Directed)으로 학습하도록 도와주는 e-러닝이 빠르게 확산되고 있다. e-러닝이 활성화 되면서 관련 분야의 연구도 활발하게 진행되고 있다. 한국과 마찬가지로 중국에서도 e-러닝 분야가 급속하게 성장하고 있으며 특히 대학 고등교육을 e-러닝으로 실시하려고 노력하고 있다. 그러나 중국 대학이 e-러닝을 효과적으로 실행하는 비율은 한국보다 낮고 e-러닝에 대한 연구도 충분히 이루어지지 않고 있다. 이에 본 연구는 한국과 중국 간의 대학 e-러닝의 학습 성과에 영향을 미치는 학습자 특성 및 교수자 특성 요인에 대한 인식도 차이를 알아보고자 한다. 이를 통해 e-러닝을 활용하고자 하는 중국 대학이나 기업에 국가별 특성에 적합한 e-러닝을 도입, 활용, 확산 등에 관련된 유용한 시사점을 제공하고자 하였다. 본 연구는 김희정･이석준･김종인(2011)의 연구에서 제시한 e-러닝의 학습자 특성 및 교수자 특성 요인을 도출하여 한국과 중국의 인식도 차이를 분석하고자 하였다. e-러닝 학습 경험이 있는 중국 대학생을 대상으로 설문지를 이용하여 자료를 수집하였으며 총 94부를 분석하였다. 간단한 기초통계를 비롯하여 신뢰도 분석과 한국과 중국 간 차이를 분석하기 위해 독립표본 T-검정 실시하였다. 분석 결과 한국과 중국 간 e-러닝의 학습자 특성과 교수자 특성의 인식에는 모두 차이가 있는 것으로 나타났는데 총 22개의 세부 요인 중 12개의 요인에서 한국과 중국 간 인식 차이가 있는 것으로 나타났다. E-learning is spreading rapidly as an alternative for traditional face-to-face ‘teaching-learning’ environment and as a tool for helping learners to study in a self-directed way by promoting and supporting their learning environment through the Internet. As e-learning is vitalized, its relevant researches are also proceeding briskly. China, like Korea, is enjoying swift growth of the e-learning sectors and especially trying to universities educations with e-learning. However, the rate of Chinese Universities’ effective use of e-learning is lower than that of Korea, and their e-learning related researches are not being achieved enough. Hence, this study will examine the perception differences in characteristic factors of learners and teachers, which influence the universities e-learning’s learning achievements in Korea and China. This will be able to help provide Chinese universities or companies with useful implications regarding the introduction, application, and diffusion of e-learnings suitable for the country’s characteristics. This study tries to analyze the perception differences between Korea and China, by deducting the characteristic factors of e-learning learners and teachers suggested in the study by Kim Hee-jung, Lee Seog-jun, and Kim Jong-in (2011). The data was collected by questionnaires targeting Chinese universities students who were having experience in e-learning use, and a total 94 of them were analyzed. Including the reliability analysis with simple basic statistics, the study conducted independent samples t-test in order to make analysis for differences between Korea and China. The analyses results indicate that the perception differences of learners and teachers exist there in all sectors between Korea and China. Out of a total of 22 detail factors, it was revealed that 12 of them show the perception differences between Korea and China.

서정의 확장과 시(詩)로 쓰는 역사

김진희 ( Jin Hee Kim ) 국제비교한국학회 2011 비교한국학 Comparative Korean Studies Vol.19 No.2

여성의 역사에 대한 고정희의 시적 탐구는 문학과 역사에서 여성을 부각시킨 중요한 작업이다. 고정희의 역사시는 여성의 역사를 재구성하려 했다는 점에서 역사로서의 의미와 의의가 있으며, 한편 그 역사가 서정 장르를 통해 재구성되고 있기 때문에 서정과 서사의 경계적 특성을 갖는다. 이 글은 ``이야기 여성사`` 연작을 중심으로 미학적 특성 및 여성주의적 문제의식을 규명하고 있다. 고정희는 부패한 권력과 오염된 언어에 대한 비판이 새로운 역사 전망과 관련된 것임을 인식하고 인간의 평등과 자유를 구현할 수 있는 해방시를 만들고자 한다. 이를 위해 다양한 문학적 장치를 사용하고 있다. 우선 역사가 과거-현재-미래가 대화한다는 점을 작품에 수용하여 다성적 목소리와 상호 텍스트성을 통해 다양한 여성 삶의 이야기를 효과적으로 드러낸다. 그리고 역사가 지닌 이야기를 전달하기 위해 서간체와 장면제 시의 서사전략을 사용하여 독자의 정서적 유대감과 참여를 확대한다. 또한 작품 안의 인물을 통해 개성과 역사성을 함께 보여줌으로써 독자가 역사와 문학, 서사와 서정의 경계 부분에서 새로운 창조적 힘을 경험하게 한다. 고정희의 역사 시편들은 역사와 문학의 경계에서 남성 중심의 역사에 대한 비판을 수행하고, 여성-어머니의 가치라는 삶의 원리에 대한 지향을 통해 미래 역사에 대한 창조적 전망과 상상을 보여준다. Goh Jung Hee`s poetic survey of women`s history is an important undertaking that highlighted the place of women in literature and history. Goh`s historical poems are meaningful and significant as a history in that they attempted to reconfigure the history of women; moreover, it is critical that we consider this history within a literary framework as it is reconstructed through the genre of lyrics. This essay defines the aesthetic features and the feminist critique of Goh`s serialized poem, "The Stories of Women`s History." Recognizing that critiquing the corruption of power and the pollution of language was related to new historical views, Goh tried to create lyrics for liberation that embodied the concepts of human freedom and equality. To this end, she employed various literary devices; first, Goh demonstrated how the past, the present, and the future converse with one another in history and effectively revealed the diverse stories of women`s lives by way of polyphonous voices and intertextuality. In delivering these stories, Goh employed the epistolary style as well as the narrative strategy for presenting scenes in order to heighten the readers` sense of interconnectedness and to foster their participation. Furthermore, she showed at once the personality and the historicity of her characters as a way to help readers experience a new creative power on the border between history and literature, and between epic and lyric. Ultimately, Goh`s historical poems criticize the male-oriented history at the boundary of history and literature, and by placing value on the principle of life, particularly that of women-mothers, her poems offer a creative outlook and imagination for the future.

남자대학생의 흡연태도와 행동에 관한 연구

강경진,김정미,민혜영,안소진,오경숙,은경희,이현,이희선,홍주미,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

There have been so many researches about problems of cigarettes and relation of smoking and heath since 1950's and generally known that smoking is one of the worst factor of increasing disease and mortality. No matter what such many proofs about various problems of smoking have been researched, smoking rate of current male collage students has not been decreased. Besides, most of the researches about cigarette use and its addiction have been focused on the adolescent or adult women smokers or adult male, not male collage student. Therefore, the subject of this study is about smoking attitude and smoking behavior of male collage students by general features. Smoking attitude was analyzed by modifying 'Guidelines for the content of tobacco smoking surveys of the general population'(WHO, 1982). Two hundred of male collage students participated to the distributed questionnaire for one week in May. The smoking attitude was categorized into duration of smoking and number of cigarette per day(CPD), and nicotine dependency, investigated by Fagerstrom Tolerance Questionnaire(FTQ) (Fagerstorm & Schneider, 1989). All statistics were performed by procedure of SAS according to number, percentage, mean, standard deviation, and ANOVA. The results are as follows: 1. Smoking attitude level was mean 25.73±5.15 marks, ranging from 13 to 39 marks of the total 40 marks. 2. Duration of cigarettes, number of cigarette per day, and nicotine dependency were mean 5.14±2.84 years, 12.88±6.85 pieces, and 4.78±1.69, respectively. 3. Smoking attitude showed significance according to general features such as marital state and allowance, but the significance according to marital state is not valuable because the numerical difference is so big between married one and single that they cannot be compared with each other. 4. Duration of smoking was significant according to general features such as age and allowance. 5. Smoking amount showed significance the factors of age only. 6. ll1ere was no significance in nicotine dependency according to general features. As a result, smoking attitude of male collage student in this study shows moderate level. Smoking attitude and duration is significant according to allowance, and smoking amount is significant according to age. Nicotine dependency according to general features is not significant but comparing with the preceding study about adult male, male collage students in this study are respectively more nicotine-dependent than adult male smokers. In conclusion, the right allowance usage strategies and effective heath education focused on the young are needed. In addition, helpful programs and information spreading strategies are necessary for establishing higher level of smoking attitude. At last, systemic regulations in daily living for ""anti-nico-dependent"" and perspective reforming of male university student are needed for reducing nicotine dependency.

영어시조에 나타난 위트에 대하여

김진희(Kim, Jin-Hee) 한국시조학회 2015 시조학논총 Vol.42 No.-

영어시조란 영어로 쓰인 시조를 말한다. 본고에서는 영어시조가 지닌 한 특성인 위트에 대해 논의하였다. 위트는 영어권에서 시조를 논의할 때 종종 주목받아온 특성이며, 실제로 영어시조에는 매력적인 위트가 보이는 작품들이 다수 존재한다. 이렇듯 위트가 영어시조에서 부각된 양상과 그 문학적 가능성을 본고에서는 살펴보았다. 비평적 의미에서의 위트는 ‘부조화의 조화’를 핵심으로 하며, 비상한 이미지나 역설, 아이러니 등을 통해 흔히 구현된다. 본고에서는 이러한 비평적 의미에서의 위트가 시조에서 구현되어 인식적?풍자적?해학적 즐거움을 유발하는 양상을 고찰하였다. 먼저 고시조에 나타난 위트의 예를 들어 비교의 자료로 삼은 후, 이어 영어시조를 살펴보았다. 경구시와 소네트 같은 기존 장르, 아이러니와 위트에 대한 오랜 문학적 관념등과의 연관 속에서 시조는 영어권에 수용되었다. 삼장 구조 중 종장의 반전이 지닌 묘미, 이에서 발생하는 아이러니와 위트는 영어권 사람들에게 시조가 어렵지 않게 수용되고 창작될 수 있었던 주요소였다. 이에 영어시조에는 위트를 통해 인식적?풍자적?해학적 즐거움을 주는 내용이 풍부하게 담길 수 있었다. 이러한 위트는 물론 고시조에도 내재되어 있는 것이다. 그러나 신랄한 풍자나 과장된 해학만이 아니라, 각박한 일상 속에서도 문득 스쳐지나가는 다양한 해학적 순간들을 포착해 낸 것은 영어시조에서 두드러지는 특징이라 할 수 있다. 일상의 힘을 북돋아 줄 수 있는 일상 속의 시로서 시조가 지닌 가능성을 영어시조는 보여 주고 있다. English sijo is the sijo poems written in English. This paper considered English sijo especially in association with its wit. In English-speaking countries, wit has been often emphasized as one of the main characteristics of the sijo genre, and it is often found in many English sijo poems. As a critical term, wit indicates a kind of "concord of discord", which consists of dissimilar images, paradox, irony, etc. This paper investigated how English sijo embodied this kind of critical wit and created three kinds of delight; those are intelligent, sarcastic, and humorous one. First, I examined old Korean sijo poems and the wit embedded in them, and then I compared them to the case of English sijo. Sijo was received in English-speaking countries in the context of the literary genre tradition such as the epigram and the sonnet, and of the literary concepts such as irony and wit. In this context, sijo, which has a three-divided semantic structure and a twist in the last part, often containing irony and wit, could be received and composed without much difficulty in Englih-speaking countries. Many English sijo poems contain wit, and they make abundant delight, which is intelligent, sarcastic, or humorous. Wit is found in Korean old sijo too, but the wit that catches humorous moments variously in everyday lives, rather than show acid sarcasm or exaggerated comic scene, is a remarkable characteristic of the English sijo. English sijo presents the possibility of the sijo genre as the poetry of everyday life, which presents various aspects of daily lives in a warm and delightful perspective.

VRE 감염증의 임상상, 미생물학적 특성 분석 및 유전적 관련성 비교 : 전국 6개 병원에서 분리된 VRE를 중심으로

정희진,박정원,엄중식,하경임,신종희,김정미,이혜수,박영희,김우주,박승철 대한감염학회 2002 감염 Vol.34 No.5

해조류를 이용한 항생재 대체 사료 첨가제 개발

박진용,김진욱,이희현,이송애,김진욱,이재화 신라대학교 자연과학연구소 2005 自然科學論文集 Vol.14 No.-

우리나라의 항생제 남용 문제는 세계적으로 심각 하다고 한다. 이러한 문제를 해결하기 위해서 정부는 다양한 정책을 도입하고 있으며 특히 축산물의 항생제 남용 문제를 해결하기위해 사료 관리법을 강화하여 항생제 사용을 억제하고 있어 항생제를 대체 할 물질이 필요하다. 이런 문제를 해결하기 위해서 우리나라의 다양한 해조류를 이용한 항생제 개발을 통해서 항생제 남용 문제를 해결하고 소비자들에게 믿을 수 있는 축산물을 제공 할 것으로 보인다. Feed official law was strengthened recently. The antibiotic use is suppressed with feed official law reinforcement. The antibiotic transfer material is necessary. To use the seaweeds and transfer the antibiotic. It is a possibility of a high income. This is new bio industry. This the goods production which is competitive power is possible. It is a possibility of eating the livestock where also the consumers are good.