Classification of Korean Rice Cultivars based on Reaction Pattern to Japanese Isolates of Blast Pathogen

Jin, Xuan-Ji,Lee, Eun-Jeong,Choi, Jae-Eul The Korean Society of Crop Science 2007 Journal of crop science and biotechnology Vol.10 No.1

Classification of blast resistance type of 129 Korean rice cultivars was carried out based on reaction pattern to 10 Japanese blast pathogen isolates(Pyricularia oryzae). The cultivars were divided into 11 groups based on the presumed resistance genes as follows; Pia type(19 cultivars), Pita-2 type(4), Pik type(3), Pib type(5), Piz type(11), Pik-s type(8), Pik and Pii type(4), Pia and Pita type(8), Pia and Pik type(6), Pita, Pik and Pii type(4) and no-grouping type(57). These results would provide important information to rice breeding for durable and broad resistance to rice blast.

Prostaglandin E1 Increases cGMP Levels in Beating Rabbit Atria: Lack of Effects of PGE1-induced Cyclic Nucleotides on Secretory and Contractile Functions

Xuan Shun Jin,He Xiu Quan,김선영,박성훈,김성주,이호섭,조경우 대한약리학회 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.5

Members of prostaglandin (PG) E-series elicit cellular effects mainly through adenylyl cyclase-cAMP signaling. The role of PGE2-induced increase in cAMP has been shown to be compartmentalized in the cardiac myocytes: PGE2-induced increase of cAMP is not involved in the control of cardiomyocytic contraction. The purpose of the present study was to define the effect of PGE1 on the cGMP levels and the role of PGE1 in the atrial secretory function. Experiments were performed in perfused beating rabbit atria and atrial contractile responses, cGMP and cAMP efflux, and atrial natriuretic peptide (ANP) secretion were measured. PGE1 increased cGMP as well as cAMP efflux concentration in a concentration-dependent manner, however, no significant changes in atrial secretory responses were observed (with 1.0μM PGE1; for cGMP, 144.76±37.5%, n=11 versus -16.81±4.76%, n=6, control, p< 0.01; for cAMP, 187.60±41.52%, n=11 versus 7.38±19.44%, n=6, control, p<0.01). PGE1 decreased atrial dynamics slightly but transiently, whereas PGE2 showed similar effects but with lower potency. Isoproterenol increased atrial cAMP efflux (with 2.0 nM; 145.71±41.89, n=5 versus 7.38±19.44%, n=6, control, p<0.05) and mechanical dynamics and decreased ANP secretion. The PGE1-induced increase in cGMP efflux showed a bell-shaped concentration-response curve. PGE1-induced increase of cGMP efflux was not observed in the presence of L-NAME, an inhibitor of nitric oxide (NO) synthase, or ODQ, an inhibitor of NO-sensitive guanylyl cyclase. L-NAME and ODQ showed no significant effect on the PGE1-induced transient decrease of atrial dynamics. These data indicate that PGE1 increases cGMP levels via NO-soluble GC signaling in the cardiac atrium and also show that PGE1-induced increases in cGMP and cAMP levels are not involved in the regulation of atrial secretory and contractile functions.

Environmental, Social, and Governance Performance and Corporate Sustainable Development in China

Xuan Wang(Xuan Wang),Shanyue Jin(Shanyue Jin) The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.1

Purpose - With the acceleration of global integration and the deepening of the market economy, sustainable development is receiving unprecedented attention worldwide. Corporate environmental, social, and governance (ESG) performance is one of the most important ways of promoting sustainable development. Companies with good ESG performance excel both operationally and financially, maintaining their competitive advantage and achieving sustainable corporate growth. This study examines the impact of ESG performance on corporate sustainability and identifies factors that influence this relationship from the perspective of external governance structures. Design/Methodology/Approach - This study investigates the impact of corporate ESG performance on corporate sustainability using a fixed-effects model with Chinese A-share listed companies from 2011 to 2020. It also explores the moderating roles of external audit quality, the shareholding ratio of institutional investors, and analyst attention on the impact of ESG performance on corporate sustainability. Findings - The findings show that corporate ESG performance can contribute to sustainable development. External audit quality, the shareholding ratio of institutional investors, and analyst attention have positive moderating effects on ESG performance, which can contribute to sustainable development. Research Implications - This study enriches theoretical research in ESG performance and sustainability, and identifies external governance factors that contribute to the relationship between the two. Consequently, it provides suggestions for listed company growth and sustainability practices

Prostaglandin $E_1$ Increases cGMP Levels in Beating Rabbit Atria: Lack of Effects of $PGE_1$-induced Cyclic Nucleotides on Secretory and Contractile Functions

Jin, Xuan Shun,Quan, He Xiu,Kim, Sun-Young,Park, Sung-Hun,Kim, Sung-Zoo,Lee, Ho-Sub,Cho, Kyung-Woo The Korean Society of Pharmacology 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.5

Members of prostaglandin(PG) E-series elicit cellular effects mainly through adenylyl cyclase-cAMP signaling. The role of $PGE_2$-induced increase in cAMP has been shown to be compartmentalized in the cardiac myocytes: $PGE_2$-induced increase of cAMP is not involved in the control of cardiomyocytic contraction. The purpose of the present study was to define the effect of $PGE_1$ on the cGMP levels and the role of $PGE_1$ in the atrial secretory function. Experiments were performed in perfused beating rabbit atria and atrial contractile responses, cGMP and cAMP efflux, and atrial natriuretic peptide(ANP) secretion were measured. $PGE_1$ increased cGMP as well as cAMP efflux concentration in a concentration-dependent manner, however, no significant changes in atrial secretory responses were observed(with $1.0{\mu}M\;PGE_1$; for cGMP, $144.76{\pm}37.5%$, n=11 versus $-16.81{\pm}4.76%$, n=6, control, p<0.01; for cAMP, $187.60{\pm}41.52%$, n=11 versus $7.38{\pm}19.44%$, n=6, control, p<0.01). $PGE_1$ decreased atrial dynamics slightly but transiently, whereas $PGE_2$ showed similar effects but with lower potency. Isoproterenol increased atrial cAMP efflux(with 2.0 nM; $145.71{\pm}41.89$, n=5 versus $7.38{\pm}19.44%$, n=6, control, p<0.05) and mechanical dynamics and decreased ANP secretion. The $PGE_1$-induced increase in cGMP efflux showed a bell-shaped concentration-response curve. $PGE_1$-induced increase of cGMP efflux was not observed in the presence of L-NAME, an inhibitor of nitric oxide(NO) synthase, or ODQ, an inhibitor of NO-sensitive guanylyl cyclase. L-NAME and ODQ showed no significant effect on the $PGE_1$-induced transient decrease of atrial dynamics. These data indicate that $PGE_1$ increases cGMP levels via NO-soluble GC signaling in the cardiac atrium and also show that $PGE_1$-induced increases in cGMP and cAMP levels are not involved in the regulation of atrial secretory and contractile functions.

High-performance liquid chromatographic determination of B3, new NAIDS drug in rat plasma : application to a pharmacokinetic study

Xuan Jin Gil,kim ji-hyun,li dong-xun,gong kyoung-hwan,prabagar balakrishnan,Rhee jong-dal,choi han-gon,yong chul soon 대한약학회 2004 大韓藥學會 總會 및 學術大會 Vol.2004 No.1

Prostaglandin E<SUB>1</SUB> Increases cGMP Levels in Beating Rabbit Atria: Lack of Effects of PGE<SUB>1</SUB>-induced Cyclic Nucleotides on Secretory and Contractile Functions

Xuan Shun Jin,He Xiu Quan,Sun Young Kim,Sung Hun Park,Sung Zoo Kim,Ho Sub Lee,Kyung Woo Cho 대한생리학회-대한약리학회 2007 The Korean Journal of Physiology & Pharmacology Vol.21 No.1

Members of prostaglandin (PG) E-series elicit cellular effects mainly through adenylyl cyclase-cAMP signaling. The role of PGE<SUB>2</SUB>-induced increase in cAMP has been shown to be compartmentalized in the cardiac myocytes: PGE<SUB>2</SUB>-induced increase of cAMP is not involved in the control of cardiomyocytic contraction. The purpose of the present study was to define the effect of PGE<SUB>1</SUB> on the cGMP levels and the role of PGE<SUB>1</SUB> in the atrial secretory function. Experiments were performed in perfused beating rabbit atria and atrial contractile responses, cGMP and cAMP efflux, and atrial natriuretic peptide (ANP) secretion were measured. PGE<SUB>1</SUB> increased cGMP as well as cAMP efflux concentration in a concentration-dependent manner, however, no significant changes in atrial secretory responses were observed (with 1.0μM PGE<SUB>1</SUB>; for cGMP, 144.76±37.5%, n=11 versus -16.81±4.76%, n=6, control, p< 0.01; for cAMP, 187.60±41.52%, n=11 versus 7.38±19.44%, n=6, control, p<0.01). PGE<SUB>1</SUB> decreased atrial dynamics slightly but transiently, whereas PGE<SUB>2</SUB> showed similar effects but with lower potency. Isoproterenol increased atrial cAMP efflux (with 2.0 nM; 145.71±41.89, n=5 versus 7.38±19.44%, n=6, control, p<0.05) and mechanical dynamics and decreased ANP secretion. The PGE<SUB>1</SUB>-induced increase in cGMP efflux showed a bell-shaped concentration-response curve. PGE<SUB>1</SUB>-induced increase of cGMP efflux was not observed in the presence of L-NAME, an inhibitor of nitric oxide (NO) synthase, or ODQ, an inhibitor of NO-sensitive guanylyl cyclase. L-NAME and ODQ showed no significant effect on the PGE<SUB>1</SUB>-induced transient decrease of atrial dynamics. These data indicate that PGE1 increases cGMP levels via NO-soluble GC signaling in the cardiac atrium and also show that PGE<SUB>1</SUB>-induced increases in cGMP and cAMP levels are not involved in the regulation of atrial secretory and contractile functions.

한국과 중국의 블렌디드 러닝 분야의 연구동향 비교

현진용(Jin-Rong Xuan),박한우(Han-Woo Park) 한국콘텐츠학회 2022 한국콘텐츠학회논문지 Vol.22 No.9

블렌디드 러닝은 능동적 학습을 촉진하고 학생의 학습 효과를 향상하기 위해 교육에서 가장 많이 사용되는 방법의 하나로 꼽히며 대학이 학습자를 유치하는 가장 효과적인 방법의 하나로 간주한다. 이 논문은 문화차원이론을 바탕으로 문화적으로 유사하면서도 차이점을 보유하고 있는 한중 양국에서 블렌디드 러닝이 이루어지는 연구 동향을 분석한다. 연구 방법은 키워드 분석 및 시각화를 이용하였고 데이터는 WoS, KISS, CNKI에서 1990년부터 2022년 6월까지 게재된 블렌디드 러닝 관련 논문을 수집하여 분석을 진행했다. 연구 결과에 따르면, 보편화된 연구주제였던 블렌디드 러닝이 코로나 발생 이후부터 다양한 연구 분야 클러스터가 형성되어 세분되고 있다. 한국과 중국도 글로벌 연구 동향과 흡사하면서 각자 색다른 연구 동향이 보인다. 문화차원이론으로 분석하면 특히 절제와 장기지향적인 공통된 패턴이 보인다. 이 연구의 기대효과는 국가 문화가 교육과 연구의 패턴을 형성하는데 어떤 역할을 하는지에 대해 파악할 수 있다는 것이다. 또한 다문화 교육환경 속에서 효과적인 학습효과를 지닌 블렌디드 러닝을 개발하는데 유의미한 시사점을 제시할 수 있다. Blended Learning is one of the most popular methods in education for encouraging active learning and improving student learning effectiveness, and it is regarded as one of the most effective methods for universities to attract students. Based on the cultural dimension theory, this paper examined blended learning research trends in both South Korea and China, which are culturally similar but also differ. The research methods include keyword analysis and visualization. Academic papers on blended learning indexed by WoS, KISS, and CNKI from 1990 to June 2022 were collected and analyzed. According to the findings, since the outbreak of COVID-19, the common research topic of blended learning has been subdivided by forming clusters in various research fields. Korea and China exhibit similarities to global research trends while exhibiting differences based on cultural background. The cultural dimension theory-based analysis reveals a common pattern that is especially long-term oriented. The findings can suggest significant implications for designing what role national culture plays in forming patterns of education and research and for developing blended learning with effective impacts in a multicultural educational environment.

Cytotoxic Oleane-type Triterpene Saponins from Glochidion eriocarpum

Nguyen Xuan Nhiem,김영호,Vu Kim Thu,Phan Van Kiem,Chau Van Minh,Bui Huu Tai,TRANHONG QUANG,Nguyen Xuan Cuong,Pham Hai Yen,Hye-Jin Boo,강정일,강희경 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.1

The anticancer activity of ten compounds from the aerial parts of Glochidion eriocarpum were evaluated on two human cancer cell lines, HL-60 and HCT-116. Compounds 1-4 displayed highly potent cytotoxic activity on the HCT-116 cancer cell line with IC50 values ranging of 0.41~1.16 μM. Compounds 1-4 significantly inhibited the HL-60 cell line with IC50 values ranging of 4.51~6.33 μM. These results suggested that the benzoyl group at the C-22 position in oleane-type triterpene saponins was essential for cytotoxicity towards tumor cells. Moreover, compounds 2 and 3 showed more potent cytotoxicity than compounds 1 and 4 against HL-60 and HCT-116 cells. With respect to the mechanism underlying cytotoxicity, compounds 1-4 increased chromatin condensation, a typical apoptotic characteristic in HL-60 and HCT-116 cells. In the mechanism of apoptosis induction, compounds 1-4 reduced Bcl-2expression, whereas the expression of Bax was increased compared to controls in HCT-116 cells. In addition, compounds 1-4 decreased the level of procaspase-3. The cleavage of poly (ADP-ribose) poly merase (PARP), a vital substrate of effector caspase, was observed in HCT-116 cells. Furthermore, the induction of apoptosis was also accompanied by an activation of extracellular signal-regulated kinase (ERK) and p38 kinase in HCT-116 cells. These findings provide evidence demonstrating that the pro-apoptotic effects of compounds 1-4 are mediated through the activation of ERK and p38 in HCT-116 cells.

A Location Method Based on Eight- Neighborhood Chain Code for Palmprint Image

Jing-xuan Jin,Rong-yi Cui 한국어정보학회 2008 한국어정보학 Vol.10 No.2

The crucial issue of precise location for on-line palmprint image was to detect corner of hand-shape contour accurately. The existing corner detection algorithm cannot extract corner useful for location automatically. Through analyzing the regularity of chain-code of hand-shape contour, a rapid and effective corner-detection method was proposed in this paper. Firstly, the method of LOG operator and eight neighborhood boundary –tracking algorithm was made use of to extract the hand-shape contour and its chain-code. Then, according to the regularity of hand-shape contour chain-code around corner, the corner of hand-shape contour was detected accurately. Finally, establish a coordinate system according to the corner detected and locate the palmprint image. The experiment results demonstrate the effectiveness and rapidness of the proposed method.

InP Quantum Dot - Organosilicon Nanocomposites

Mai Xuan Dung,Priyaranjan Mohapatra,Jin-Kyu Choi,Jin-Hyeok Kim,Sohee Jeong,Hyun-Dam Jeong 한국진공학회 2012 한국진공학회 학술발표회초록집 Vol.2012 No.2