Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

Microwave Absorption Characteristics of U-Type Ferrite Powders According to Substitution Elements and Its Compositions

Kwang‑Pil Jeong,Su‑Won Yang,Jin‑Hyuk Choi,Jeong‑Gon Kim 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.8

In this study, partially substituted U-type ferrite (Ba4MexCo2-xFe36O60, Me: Mn, Ni, Zn, x=0.5 and 1.0) powders weresynthesized by sol–gel method. The powders were analyzed for phase formation, morphology and magnetic properties byXRD, FE-SEM and VSM respectively. The synthesized ferrite powders were pressed into a series of toroidal shaped samples,in which the weight ratio of parafn to powder was 1:5. The complex scattering parameters were measured by using vectornetwork analyzer in the frequency range of 2–18 GHz and were employed in the calculation of refection loss with variousthicknesses. The minimum refection loss was observed in the substituted nickel sample as−24.4 dB (absorption rate 99.6%)with a thickness of 2.5 mm and the bandwidth was achieved 4.8 GHz (from 7.5 to 12.3 GHz) for refection loss≤ −10 dBin the substituted zinc sample.

FDM 장치에서 주사량과 시제품의 경사가 표면거칠기에 미치는 영향

권광진,전재억,정진서,김광희,하만경 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

Competitive power is rapidly manufacture product required consumers. Therefore, modern industry have changed from small item many production to many item small production. rapid production is necessary thing at the product development. Thus, rapid prototyping is appeared. If the graphic model was made by CAD, the production can be made in short term. That provide what the part was directly tested by the worker. It provide believable data. This study is experiment on surface roughness of part at FDM

티부틸디메틸실릴옥시기를 포함하는 퓨록산 유도체의 합성에 관한 연구

黃匡鎭,金光鎭,金鎭國 홍익대학교 산업기술연구소 2000 産業技術 Vol.10 No.-

The furoxan 6 containing TBDMS group was prepared by the dimerization of the corresponding nitric oxide that was generated in situ from the N-hydroxy iminoyl chloride 5. The synthetic route for the furoxan containing TBDMS provides more efficient NMR spectroscopic analysis to that using THP as a hydroxyl protecting group. In addition to this,the yield in [3+2] cycloaddition of the corresponding nitric oxide for the furoxan 6 was higher (〉95%) than that in the reaction using THP protecting group. Those results suggest us thst TBDMS group is considered as better protecting group than THP for the synthesis of furoxan containing thiol group.

통합체육수업이 장애대학생과 일반대학생의 태도에 미치는 영향

오광진 한국특수체육학회 2005 한국특수체육학회지 Vol.13 No.1

The purpose of this study was to identify the effects of inclusive physical education lessons on attitudes of college students with and without disabilities. Subjects for this study were college students with and without disabilities participating in inclusive physical education lessons in H college which was built for inclusion education. The samples included 197 college students (students with disabilities = 87, students without disabilities = 110). The questionnaire concerning attitudes toward inclusive physical education was developed by Oh Kwang-Jin (2001b) which consisted of 6 factors, 26-item, 5 of socio-demographics variables, and 6 of background variables. Independent t-test, Paired t-test, and One-way ANOVA were used for data analyses, and the reliability was confirmed by Cronbach's a value. Cronbach's a value was .88. The results were as follows: First, there was no significant difference in attitude toward inclusive physical education between college students with and without disabilities at pre (after 3-week) and post (after 15-week) test points, however there was a significant difference in attitude toward inclusive physical education within each college students with and without disabilities. Second, first and second semester college students didn't have significant difference in attitude toward inclusive physical education. Third, previous experiences in inclusive education lessons had significant difference on attitudes toward inclusive physical education. Four, previous experiences in inclusive physical education lessons had significant difference on attitudes toward inclusive physical education. Fifth, understanding of disability traits made a significant difference in attitudes toward inclusive physical education. These results implied attitudes toward inclusive physical education of college students with and without disabilities will be changed more positively, if they participated in inclusive physical education lessons systematically during 12 weeks.

진해만 해성점토의 토질특성에 관한 연구

이광열,윤성현,홍진원,안용수 東西大學校 2001 동서논문집 Vol.7 No.-

This study presents the physical and mechanical characteristics of dredged clays from Jin-Hae costar area. Dredged clays generally used as a land reclamation materials for land use in the shoreline. Experimental studied were performed on the samples directly obtained from the field. The results of direct shear test, unconfined test and consolidation test were presented for variable water contents. From the study, it is indicated that the strength of soil is decreased as increase of water contents, and the strength is increased as time passing.

일반중학생의 통합체육에 대한 태도 연구

오광진,최승권,김기영 한국특수체육학회 2002 한국특수체육학회지 Vol.10 No.1

the purpose of this study was to examine the middle school students' attitude toward inclusive physical education of students with disabilities. Subjects for this study was middle school students of 7-9 grades living in Seoul, South Korea The sample number used in the analysis was 497. The questionnaire concerning the middle school students' attitudes toward inclusive physical education was developed by Kwang-Jin Oh(2001) who consisted of 6 factors, 26-item. The reliability of the questionnaire was confirmed based on the calculation of Chronbach's α value. Chronbach's α value was .8753. This study produced the following results. First, the middle school students' attitudes toward inclusive physical education of students with disabilities according to gender, grades, experience of inclusive education, having friends with disabilities, and experience of inclusive physical education had significant differences. Second, gender and start of inclusive physical education had negative effects on attitude toward inclusive physical education of students with disabilities. These findings reported the middle school students contacted with students with disabilities had negative attitudes toward inclusive physical education.

이병주의 <철학적 살인>에 나타난 사랑의 법적 한계

안광진 ( An Kwang-jin ) 순천대학교 인문학술원 2019 인문학술 Vol.3 No.-

이병주의 단편소설 <철학적 살인>은 간통의 문제를 직접적인 소재로 잡고 법과 문학의 한계와 외연을 보여주고 있는 작품이다. 주인공 민태기는 대학시절 자신과 라이벌이었던 고광식이 아내와 정을 통하고 있다는 생각에 살인을 저지르고 만다. 그리고 그 행위에 대한 철학적 합리화와 고민을 통해 작가는 간통의 문제와 사랑의 책임, 주인공의 심리상태를 작가 나름의 치열한 의식을 통해 보여주고 있다. 이 소설이 보여주고 있는 문학과 법률과의 상관관계를 해석해 본다면, 첫째, 문학은 결코 법을 통해서 인간의 문제를 해결하지 않는다. 되려 법과 다른 차원에서 그 인간성의 자유로움과 구원을 추구하고 있다. 둘째, 문학은 법적 처벌과는 달리, 또한 인간적 신념과 철학이라 간주되는 것과도 달리, 가장 인간적인 본성을 드러내 보이는 데 그 초점을 맞추고 있다는 것이다. 결코 법의 처벌과 징계를 받고 있는 인간이라 해도 그 법을 인정하고 순응하지는 않는다는 것이 인간이라는 입장이다. 문학은 법적 처벌을 받는 인간을 다룬다 해도 법이 대상이 아니라 인간이 대상이라는 것이다. 셋째, 문학은 법적 처벌과는 달리 인간의 구원 가능성에 대한 희망 또한 제시하고 있다는 점이다. 전체적으로 소설 <철학적 살인>은 이병주의 작품들이 대개 그러하듯이 극적인 상황에서 인간이 처한 사랑과 질투와 구원의 문제를 심리적 묘사의 치열함으로 수준 높게 형상화한 작품이다. 작품의 진가는 주인공의 확신에 찬 살인 행위가 점차 변화과정을 겪으며 인간본성의 근저를 건드리고 구원의 가능성을 열어두는 부분이라 볼 수 있다. 한편 이 소설에서는 다시 한번 인간을 대하는 문학과 법률의 차이를 간결하게 보여주고 있다. Lee Byung-ju's short novel < Philosophy Murder > shows a direct subject of adultery, demonstrating the limitations and expansion of law and literature. The main character, Min Tae-gi, commits murder because he thinks Ko Kwang-shik, who was his rival in college, has an affair with his wife. And through the philosophical rationalization and agony of the main character, the author shows the problem of adultery, the responsibility of love, and the psychological state of the protagonist through the intense consciousness of the writer himself. If you interpret the correlation between the literature and the law that this novel shows, First, literature never solves human problems through law. It seeks freedom and salvation of human nature at a different level from the law. Second, literature, unlike legal punishment, also focuses on revealing the most human nature, as opposed to calling for human conviction and philosophy. They say that even a human being who is being punished and disciplined by the law, the literature does not going to accept the law. Third, literature, unlike legal punishment, also offers hope for the possibility of human salvation. Overall, the novel < Philosophical Murder > depicts the love, jealousy, and salvation of human beings in dramatic situations, as it is usually the case with Lee Byung-ju's works, with the intensity of psychological description. The true value of the story is that the protagonist's convincing murder is gradually undergoing a process of change touching the root of human nature and opening up the possibility of redemption. This novel, meanwhile, once again concisely illustrates the difference between literature and law.

FDM에서 Build Orientation이 쾌속조형물의 표면에 미치는 영향

전재억,서진호,권광진,권혁준,정진서,하만경 한국공작기계학회 2002 한국공작기계학회 춘계학술대회논문집 Vol.2002 No.-

Fused deposition (FD) modeling by Stratasys Inc., is one of the material deposition subfamilies of solid freeform fabrication (SFF) technologies. In this process, build material in the form of a flexible filament, is heated to a semi-liquid state and extruded from a controlled deposition head onto a fixtureless table in a temperature controlled environment. The position of nozzle is computer controlled relative to the base, which allows geometric complex models to be made to precise dimensions. FDM provide what the part was directly tested by the worker. It provide believable data. This Study is identify to surface roughness by build orientation adjustment. So, the paper is the study on surface roughness by build orientation at FDM.

세포질내 정자주입법(ICSI)에 있어서 정자흡입 및 난자내 주입방법에 관한 연구

이택후,김항진,송건호,김대근,전상식,박윤규,서태광,전병균,류은경,이은숙,문진수,김광철 경북대학교 의학연구소 2000 경북대학교병원의학연구소논문집 Vol.4 No.1

Study on Method of Sperm Aspiration and Injection into an Oocyte in Intracytoplasmic Sperm Injection(ICSI) Immobilization of spermatozoa prior to intracytoplasmic sperm iniection(ICSI) sometimes results in crooked tail and this makes it difficult to aspirate sperm into an injection pipette tail first. Head-first sperm aspiration into an injection pipette avoid this problem due to the bigger size of the sperm head. The effect of head or tail-first sperm injection into an oocyte on fertilization cleavage, percentage of grade I embryos and development to blastocyst stage in ICSI program has been studied. A single living immobilized spermatozoa from oligoasthenozoospermic patient was injected into an oocyte head-first or tail-first according to the treatment. Eighteen hours after microinjection, oocytes ware inspected for survival and fertilization Fertilized oocytes with two pronuclei were cultured in 30μl drop of mHTF supplemented with 10% heat-inactivated follicular fluid(FF) at 37℃. On day 2. embryo transfer was performed with cleaved embryos. The remaining 2-8 cell stage embryos were co-cultured with BRL cells in mHTF + 10% FF for 72 hours and the developmental stage was observed. The data were analyzed by Analysis of Variance. A total of 164 oocytes from 36 cycles were assigned to earth treatment and ICSI was performed(88 head-first, tail-first). The rates of normal fertilization were 81.8% and 76.3% for head-first and tail-first, respectively. Of the fertilized oocytes, the percentage of cleaved embryos and the percentage of grade 1 embryo among cleaved embryos were 88.9% and 68.8%, 93.1% and 74.1% for head-first and tail-first, respectively. Of the 2-8 cell embryos cultured, 44.4%(16/36) and 50.0%(10/20) for head first and tail first, respectively developed to blastocyst stage. There were no differences in fertilization, cleavage, rates of grade 1 embryos, and development to blastocyst stage. In conclusion, head-first or tail-first sperm injection into an oocyte in ICSI program does not affect fertilization and subsequent embryo development to blastocyst stage in vitro.