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Jianxue Liu,Yonghao Ji,Hong Ai,Bo Ning,Junzhi Zhao,Yaoren Zhang,Guoliang Dun 대한영상의학회 2016 Korean Journal of Radiology Vol.17 No.3
Objective: To compare several noninvasive indices of fibrosis in chronic viral hepatitis B, including liver shear-wave velocity (SWV), hyaluronic acid (HA), collagen type IV (CIV), procollagen type III (PCIII), and laminin (LN). Materials and Methods: Acoustic radiation force impulse (ARFI) was performed in 157 patients with chronic viral hepatitis B and in 30 healthy volunteers to measure hepatic SWV (m/s) in a prospective study. Serum markers were acquired on the morning of the same day of the ARFI evaluation. Receiver operating characteristic (ROC) analysis was performed to evaluate and compare the accuracies of SWV and serum markers using METAVIR scoring from liver biopsy as a reference standard. Results: The most accurate test for diagnosing fibrosis F ≥ 1 was SWV with the area under the ROC curve (AUC) of 0.913, followed by LN (0.744), HA (0.701), CIV (0.690), and PCIII (0.524). The best test for diagnosing F ≥ 2 was SWV (AUC of 0.851), followed by CIV (0.671), HA (0.668), LN (0.562), and PCIII (0.550). The best test for diagnosing F ≥ 3 was SWV (0.854), followed by CIV (0.693), HA (0.675), PCIII (0.591), and LN (0.548). The best test for diagnosing F = 4 was SWV (0.965), followed by CIV (0.804), PCIII (0.752), HA (0.744), and LN (0.662). SWV combined with HA and CIV did not improve diagnostic accuracy (AUC = 0.931 for F ≥ 1, 0.863 for F ≥ 2, 0.855 for F ≥ 3, 0.960 for F = 4). Conclusion: The performance of SWV in diagnosing liver fibrosis is superior to that of serum markers. However, the combination of SWV, HA, and CIV does not increase the accuracy of diagnosing liver fibrosis and cirrhosis.
Jianxue Wang,Ruogu Wang,Pingliang Zeng,Shutang You,Yunhao Li,Yao Zhang 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.3
Traditional transmission planning usually caters for rated wind power output. Due to the low occurrence probability of nominal capacity of wind power and huge investment in transmission, these planning methods will leads to low utilization rates of transmission lines and poor economic efficiency. This paper provides a novel transmission expansion planning method for integrating largescale wind power. The wind power distribution characteristics of large-scale wind power output and its impact on transmission planning are analyzed. Based on the wind power distribution characteristics, this paper proposes a flexible and economic transmission planning model which saves substantial transmission investment through spilling a small amount of peak output of wind power. A methodology based on Benders decomposition is used to solve the model. The applicability and effectiveness of the model and algorithm are verified through a numerical case.
Wang, Jianxue,Wang, Ruogu,Zeng, Pingliang,You, Shutang,Li, Yunhao,Zhang, Yao The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.3
Traditional transmission planning usually caters for rated wind power output. Due to the low occurrence probability of nominal capacity of wind power and huge investment in transmission, these planning methods will leads to low utilization rates of transmission lines and poor economic efficiency. This paper provides a novel transmission expansion planning method for integrating large-scale wind power. The wind power distribution characteristics of large-scale wind power output and its impact on transmission planning are analyzed. Based on the wind power distribution characteristics, this paper proposes a flexible and economic transmission planning model which saves substantial transmission investment through spilling a small amount of peak output of wind power. A methodology based on Benders decomposition is used to solve the model. The applicability and effectiveness of the model and algorithm are verified through a numerical case.
Pynomial modeling for efficient predistortion of HPA
Hieu, Nguyen Thanh,Jianxue, Jin,Ryu, Heung-Gyoon 충북대학교 컴퓨터정보통신 연구소 2004 컴퓨터정보통신연구 Vol.12 No.3
High power amplifier (HPA) in transmitter of communication systems usually operates in near saturation point in order to achieve the maximum power efficiency. In this region, undesirable nonlinear distortions may be introduced. In this paper, we present a polynomial modeling method used for efficient predistortion to compensate for the nonlinear distortion. The polynomial models are derived from the electrical parameters in data sheets of actual amplifiers such as gain, the third order intercept point of output power and 1dB compression point. We can find the polynomial coefficients of predistorter from the HPA polynomial modeling. Then, it is simple and effective to suppress the nonlinear distortion. We also study the effects of predistortion on the SER performance of communication system with 16-QAM modulation format. From the simulation results, it can be shown that BER performance is improved by the proposed efficient predistortion.
Dongyang Ma,Liling Ren,Zhen Cao,Jianxue Li,Jian Cao,Wenyan Tian,Hong Yao 한국조직공학과 재생의학회 2016 조직공학과 재생의학 Vol.13 No.5
The repair of bone defects poses a great challenge for reconstructive surgeons. Although the development of tissue engineering has exhibited promise in replacing damaged bone, the fabrication of large constructs with functional blood vessels remains an obstacle. From the orthopedic surgeon’s point of view, the generation of axially vascularized bone, which can anastomose with the recipient vessel, might be a solution to this medical problem. In this study, we aimed to prefabricate an axially vascularized bone by combining a β-TCP scaffold, arteriovenous loop (AVL), and cell sheet in a bioreactor in vivo. Twelve rabbits were randomly allocated into two groups: the experimental group (presence of AVL) and the control group (absence of AVL). The constructs were explanted at 8 weeks postoperatively. The histomorphometric results showed 42.8±5.9% of the bone area in the AVL group and 26.6±3.5% in the control group. Similarly, vessel analysis revealed the average vessel density in the AVL group (12.5±3.3) was significantly more than that in the control group (6.1±1.5, p<0.05). Our research indicated that the combination of a β-TCP scaffold, AVL and cell sheet might engineer vascularized bone. This prefabrication strategy might facilitate clinical translation of bone tissue engineering in reconstructing large bone defects.
The topographic effect of ground motion based on Spectral Element Method
Liu, Xinrong,Jin, Meihai,Li, Dongliang,Hu, Yuanxin,Song, Jianxue Techno-Press 2017 Geomechanics & engineering Vol.13 No.3
A Spectral Element Method for 3D seismic wave propagation simulation is derived based on the three-dimensional fluctuating elastic dynamic equation. Considering the 3D real terrain and the attenuation characteristics of the medium, the topographic effect of Wenchuan earthquake is simulated by using the Spectral Element Method (SEM) algorithm and the ASTER DEM model. Results show that the high PGA (peak ground acceleration) region was distributed along the peak and the slope side away from the epicenter in the epicenter area. The overall distribution direction of high PGA and high PGV (peak ground velocity) region is parallel to the direction of the seismogenic fault. In the epicenter of the earthquake, the ground motion is to some extent amplified under the influence of the terrain. The amplification effect of the terrain on PGA is complicated. It does not exactly lead to amplification of PGA at the ridge and the summit or attenuation of PGA in the valley.
Jian Xue,Zefei Jiang,Fan Qi,Shuanghong Lv,Shaohua Zhang,Tao Wang,Xiaozhong Zhang 한국유방암학회 2014 Journal of breast cancer Vol.17 No.4
Purpose: In the present study, we investigated the incidence ofcardiotoxicity within 5 years of trastuzumab treatment and evaluatedpotential risk factors in clinical practice. Methods: The studycohort included 415 patients diagnosed with early breast cancer(EBC). Cardiotoxicity incidence was evaluated in patients receivingtrastuzumab and those who did not. Multivariate Cox proportionalhazards regression models were used to estimate hazardratios and 95% confidence intervals of potential risk factorsfor trastuzumab-related cardiotoxicity after appropriate adjustments. Results: Incidence of cardiotoxicity in patients treatedwith trastuzumab was significantly higher than that in controls(23.7% vs. 10.8%, p<0.001). This result was adjusted for factorsthat might increase the risk of cardiotoxicity, such as historyof coronary artery diseases or the use of anthracyclines for morethan four cycles. Conclusion: Our findings indicated that treatmentwith trastuzumab was strongly associated with cardiotoxicityin EBC patients.