Static aerodynamic force coefficients for an arch bridge girder with two cross section

Jian Guo,Minjun Zhua 한국풍공학회 2020 Wind and Structures, An International Journal (WAS Vol.31 No.3

Aiming at the wind-resistant design of a sea-crossing arch bridge, the static aerodynamic coefficients of its girder (composed of stretches of π-shaped cross-section and box cross-section) were studied by using computational fluid dynamics (CFD) numerical simulation and wind tunnel test. Based on the comparison between numerical simulation, wind tunnel test and specification recommendation, a combined calculation method for the horizontal force coefficient of intermediate and small span bridges is proposed. The results show that the two-dimensional CFD numerical simulations of the individual cross sections are sufficient to meet the accuracy requirements of engineering practice.

Applications of carbon-based materials in solid phase micro-extraction: a review

Jian Guo,Soo-Jin Park,Long-Yue Meng,Xinghua Jin 한국탄소학회 2017 Carbon Letters Vol.24 No.-

Use of multi-hybrid machine learning and deep artificial intelligence in the prediction of compressive strength of concrete containing admixtures

Jian, Guo,Wen, Sun,Wei, Li Techno-Press 2022 Advances in concrete construction Vol.13 No.1

Conventional concrete needs some improvement in the mechanical properties, which can be obtained by different admixtures. However, making concrete samples costume always time and money. In this paper, different types of hybrid algorithms are applied to develop predictive models for forecasting compressive strength (CS) of concretes containing metakaolin (MK) and fly ash (FA). In this regard, three different algorithms have been used, namely multilayer perceptron (MLP), radial basis function (RBF), and support vector machine (SVR), to predict CS of concretes by considering most influencers input variables. These algorithms integrated with the grey wolf optimization (GWO) algorithm to increase the model's accuracy in predicting (GWMLP, GWRBF, and GWSVR). The proposed MLP models were implemented and evaluated in three different layers, wherein each layer, GWO, fitted the best neuron number of the hidden layer. Correspondingly, the key parameters of the SVR model are identified using the GWO method. Also, the optimization algorithm determines the hidden neurons' number and the spread value to set the RBF structure. The results show that the developed models all provide accurate predictions of the CS of concrete incorporating MK and FA with R² larger than 0.9972 and 0.9976 in the learning and testing stage, respectively. Regarding GWMLP models, the GWMLP1 model outperforms other GWMLP networks. All in all, GWSVR has the worst performance with the lowest indices, while the highest score belongs to GWRBF.

Tristetraprolin Overexpression in Gastric Cancer Cells Suppresses PD-L1 Expression and Inhibits Tumor Progression by Enhancing Antitumor Immunity

Jian Guo,Huiheng Qu,Ting Shan,Yigang Chen,Ye Chen,Jiazeng Xia 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.7

The RNA-binding protein tristetraprolin (TTP) binds to adenosine- uridine AU-rich elements in the 3’-untranslated region of messenger RNAs and facilitates rapid degradation of the target mRNAs. Therefore, it regulates the expression of multiple cancer and immunity-associated transcripts. Furthermore, a lack of TTP in cancer cells influences cancer progression and predicts poor survival. Although the functions of TTP on cancer cells have previously been researched, the mechanism of TTP on the interaction between cancer cells with their microenvironment remains undiscovered. In this study, we admed to determine the role of cancer cell TTP during the interaction between tumor and immune cells, specifically regulatory T cells (Tregs). We evaluate the capability of TTP to modulate the antitumor immunity of GC and explored the underlying mechanism. The overexpression of TTP in GC cells dramatically increased peripheral blood mononuclear lymphocyte (PBML) -mediated cytotoxicity against GC cells. Increased cytotoxicity against TTP-overexpressed GC cells by PBMLs was determined by Treg development and infiltration. Surprisingly, we found the stabilization of programmed death-ligand 1 (PD-L1) mRNA was declining while TTP was elevated. The PDL1 protein level was reduced in TTP-abundant GC cells. PD-L1 gas been found to play a pivotal role in Treg development and functional maintenance in immune system. Taken together, our results suggest the overexpression of TTP in GC cells not only affects cell survival and apoptosis but also increases PBMLs -mediated cytotoxicity against GC cells to decelerate tumor progression. Moreover, we identified PD-L1 as a critical TTP-regulated factor that contributes to inhibiting antitumor immunity.

Contradiction

Jian Guo,Lu Fu 한국콘텐츠학회 2013 ICCC International Digital Design Invitation Exhib Vol.2013 No.-

A CFD Prediction of the Gas-Solid Suspension Flow through a Supersonic Nozzle

JianGuo Sun,Heuy Dong Kim,YingZi Jin 한국추진공학회 2012 한국추진공학회 학술대회논문집 Vol.2012 No.11

In many engineering applications such as rocket propulsions and pneumatic devices, the gas flows containing very fine solid particles are employed frequently. The presence of particles in high-speed flows results in a very complicated and interesting phenomena due to particle-turbulence interactions. It is difficult as well as costly to investigate such suspension flows. CFD approach may be a good means to get insight into the gas-solid suspension flows. The present study investigates the effect of particle diameter on the gas solid suspension flow through a supersonic nozzle. The numerical model based on the Discrete Phase Model (DPM) has been employed to simulate the particle movement. The results show that the different sizes of particle have different influence on the gas phase behavior. The structure of shock train, the separation point, and the vortex of the backflow are all changed as the particle diameter varied from small size to large size. As the particle diameter increases the flow characteristics behave differently. The separation point first moves toward the downstream, but after the critical value of the diameter, it moves back to upstream. The change of gas flow behavior in turn affects the particle distribution. When the particle diameter is too small or too big, the particle concentration at the shear layer will be weak.

Structural Characterization of Microwave-Assisted Solution-Synthesized Strontium-Substituted Hydroxyapatite

Jianguo Liao,Yanqun Li,Xiali Guan,Jingxian Liu,Yongxiang Zhang,Yufen Xie,Zhengpeng Yang,Xingze Duan,Aiguo Zhou,Jiangnan Zhu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.10

Hydroxyapatite and strontium-substituted hydroxyapatite nanoparticles (n-HA and Sr-HA) were prepared by microwave-assisted solution synthesis with aqueous solutions of various Sr/(Sr+Ca) molar ratios ranging from 0% to 15%. The structural properties of the hydroxyapatite powders were investigated by X-ray powder diffraction, Fourier transform infrared spectroscopy and Raman spectra, field emission scanning electron microscopy coupled with energy dispersive X-ray spectrometry and transmission electron microscopy. The results confirmed that strontium ions had been incorporated into the hydroxyapatite lattice. The synthetic n-HA and Sr-HA nanocrystalline consisted of hydroxyapatite crystalline phase with hexagonal structure, and the particle size was 30–40 x 60–70 nm and 40–50 x 70–80 nm, respectively. The calcined HA particle size ranged from about 120 nm to 150 nm, the calcined Sr-HA products were composed of spherical aggregates with a size of about 70–100 nm. The incorporation of Sr ions lead to the formation of vacancies in the crystal structure of the HA. The results indicated that the strontium substitution did not change the crystal structures. More Sr resulted in less calcined crystallites and formed agglomerates owing to the size effect.

Static analysis of a radially retractable hybrid grid shell in the closed position

Jianguo Cai,Chao Jiang,Xiaowei Deng,Jianfeng Zhao,Yixiang Xu 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.6

A radially retractable roof structure based on the concept of the hybrid grid shell is proposed in this paper. The single-layer steel trusses of the radially foldable bar structure are diagonally stiffened by cables, which leads to a single-layer lattice shell with triangular mesh. Then comparison between the static behavior between the retractable hybrid grid shell and the corresponding foldable bar shell with quadrangular mesh is discussed. Moreover, the effects of different structural parameters, such as the rise-to-span ratio, the bar cross section area and the pre-stress of the cables, on the structural behaviors are investigated. The results show that prestressed cables can strengthen the foldable bar shell with quadrangular mesh. Higher structural stiffness is anticipated by introducing cables into the hybrid system. When the rise-span ratio is equal to 0.2, where the joint displacement reaches the minimal value, the structure shape of the hyrbid grid shell approaches the reasonable arch axis. The increase of the section of steel bars contributes a lot to the integrity stiffness of the structure. Increasing cable sections would enhance the structure stiffness, but it contributes little to axial forces in structural members. And the level of cable prestress has slight influence on the joint displacements and member forces.

New DPWM Method to Suppress the Low Frequency Oscillation of the Neutral-Point Voltage for NPC Three-Level Inverters

Jianguo Lyu,Wenbin Hu,Fuyun Wu,Kai Yao,Junji Wu 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.5

In order to suppress the low frequency oscillation of the neutral-point voltage for three-level inverters, this paper proposes a new discontinuous pulse width modulation (DPWM) control method. The conventional sinusoidal pulse width modulation (SPWM) control has no effect on balancing the neutral-point voltage. Based on the basic control principle of DPWM, the relationship between the reference space voltage vector and the neutral-point current is analyzed. The proposed method suppresses the low frequency oscillation of the neutral-point voltage by keeping the switches of a certain phase no switching in one carrier cycle. So the operating time of the positive and negative small vectors is equal. Comparing with the conventional SPWM control method, the proposed DPWM control method suppresses the low frequency oscillation of the neutral-point voltage, decreases the output waveform harmonics, and increases both the output waveform quality and the system efficiency. An experiment has been realized by a neutral-point clamped (NPC) three-level inverter prototype based on STM32F407-CPLD. The experimental results verify the correctness of the theoretical analysis and the effectiveness of the proposed DPWM method.

Influence of Solution Concentrations on Surface Morphology and Wettability of ZnO Thin Films

Jianguo Lv,Changlong Liu,Feng Wang,Zhitao Zhou,Zhenfa Zi,Yuan Feng,Xiaoshuang Chen,Feng Liu,Gang He,Shiwei Shi,Xueping Song,Zhaoqi Sun 대한금속·재료학회 2013 ELECTRONIC MATERIALS LETTERS Vol.9 No.2

ZnO thin films were grown on silicon substrates using a hydrothermal method. The XRD patterns show that all of the peaks can be attributed to the wurtzite structures of ZnO. The TC value of (002) plane and average crystal size increase first and then decrease with the increase of solution concentration. SEM and AFM results show that many dense hexagonal cylinder particles have been observed on the surface of the thin films, which grown at 0.08 and 0.10 mol/L. The surface roughness of the thin films deposited at 0.06,0.08, 0.10, and 0.12 mol/L are 24.5, 38.3, 32.0, and 39.4 nm, respectively. Surface wettability results show that the preferential orientation along c-axis and surface roughness contribute significantly to the hydrophobicity. The reversible switching between hydrophobicity and hydrophilicity is related to the synergy of the transition of wetting model, surface crystal structure, and surface roughness.