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      • Detection and Prognostic Analysis of Serum Protein Expression in Esophageal Squamous Cell Cancer

        Jiang, Hong,Wang, Xiao-Hong,Yu, Xin-Min,Zheng, Zhi-Guo Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

        Objective: To assess differences in serum proteins in esophageal squamous cell carcinoma patients. Methods: 144 esophageal squamous cell carcinoma patients and 50 healthy volunteers were included in this study, with surface-enhanced laser desorption-ionization time-of-flight mass spectrometry and weak cation exchange magnetic beads. Follow-up allowed the relations between serum proteins and prognosis to be analyzed. Results: A total of 93 protein peaks were detected (molecular weight range: 1500-30000), 10 demonstrating statistically significant differences. There were no differences in protein peaks between 92 patients with a survival more than 2 years and 52 patients with survival less than 2 years. There were two significantly different protein peaks between 45 stage II patients with a survival more than 2 years and 14 stage II patients with survival less than 2 years. There was one significantly different protein peak between 22 stage III patients with a survival more than 2 years and 29 stage III patients with survival less than 2 years. Conclusion: Differences of serum proteins in esophageal squamous cell carcinoma are related to prognosis of patients. The protein fingerprint can be helpful for clinical diagnosis and treatment.

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        A comprehensive study on a propagating buckle in externally pressurized pipelines

        Jianghong Xue,Neng Gan 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.12

        Buckle propagation is a unique phenomenon occurring in deep-sea pipelines. In previous works, this phenomenon was investigated usinga ring technique in which the pipeline was assumed to be in plane strain condition and the energies absorbed in membrane stretchingand longitudinal bending were ignored. This paper presents a three-dimensional analysis of the buckle propagation phenomenon with anemphasis to address more complete factors that were not accounted for in the ring analysis. The analyses are based on the available solutionsof the transition zone obtained in our previous works. A comprehensive mechanism for buckle propagation phenomenon is describedfrom the point view of plastic stability theory for shells which enables the incorporation of the effects of transverse and longitudinalbending, membrane stretching and material strain hardening. The nondimensionalized buckle propagation pressure is represented interms of yield coefficient, strain hardening coefficient and membrane stretching factor. It is found that a buckle once initiated in a pipelinemay or may not propagate along the pipeline depending on its radius-to-thickness ratio. By comparing with various experimentalresults the theoretical predictions from this analysis are shown to provide very accurate estimations of the buckle propagation pressure fordifferent materials with diverse geometric parameters and material properties. This paper points to the need for more complete informationregarding the effects of transverse bending, membrane stretching and material strain-hardening on the buckle propagation pressure. Upon the requirement of application variations of the yield coefficient, strain hardening coefficient and membrane stretching factor withrespect to the radius-to-thickness ratio are sketched out. This eliminates the need for recourse the curves and allows a fast and convenientresolution of buckle propagation pressure for certain pipeline. Most importantly, the present analysis offers the potential for future designof pipelines being at once more rationally and parametrically complete, and yet compact and simple to apply.

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        Orthotropic Analysis of Steel Deck–Girder–Rib Systems Subjected to Transverse Load

        Mu Chen,Jianghong Xue,Ping Li,Fusong Jin 한국강구조학회 2019 International Journal of Steel Structures Vol.19 No.3

        As one of the advanced modern techniques, orthotropic steel decks are widely used in bridge engineering. Because of its structural complexity, theoretical analysis of mechanical performances of the orthotropic steel bridge deck is very diffi cult. Therefore, in the past 50 years, a series of experiments and fi nite element analysis have been used to obtain the information. A steel deck–girder–rib bridge system subjected to the transverse load is investigated in this paper. The bridge deck is laid on four simply-supported girders at the four edges and is reinforced by ribs in longitudinal direction. The longitudinally stiff ened deck is idealized as an orthotropic plate. The equivalent material properties in the longitudinal and breadth directions of the orthotropic plate are evaluated using micro-mechanics of composite material by treating the ribs as reinforcing fi ber-beams. Governing equations for the deck–girder–rib bridge systems are established and are solved using Ritz method. The analytical solutions are substantiated by comparing with the classic solutions of an isotropic deck with fi xed ends and with the fi nite element predictions. The analytical approach presented in this paper eliminates the very intricate and arduous kinematics study among deck–girder–rib and allows the bridge engineer to fast and convenient estimate the deformation in an orthotropic bridge deck.

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        Calculation of Deflection and Stress of Assembled Concrete Composite Beams under Shrinkage and Creep and Its Application in Member Design Optimization

        Yan Fang,Jianghong Mao,Yixue Zhang,Weiliang Jin,Diwei Tang,Jun Zhang 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.9

        There are a large number of concrete bonding interfaces in assembled concrete structures. Moreover, the problems of deformation and coordination at the interfaces lead to weak bonding under shrinkage and creep. The theoretical methods and analytical solutions for the long-term performance of composite structures in recent literatures are relatively complicated for the review or optimization in the design stage. Hence, a method for calculating the mid-span deflection of and the cross-sectional stress on composite beams under shrinkage and creep was developed based on the average curvature method. The calculation method was then verified by the experiments and the numerical simulations. Further, factors affecting the deflection of and the stress on the assembled concrete composite beams, including the loading age, the reinforcement ratio, the section dimensions, and the surface area in contact with the atmosphere were analyzed by using the developed method. The results revealed that the adjustment of the section dimensions and the loading time is the effective optimization approach. A framework for review or optimization of composite concrete beams based on the sensitivity analysis is proposed and a case study is carried out. The results of this work can helpfully be used to control the risk of additional deflections or cracking during the long-term operation of buildings.

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        A Generalized Markov Chain Model for IEEE 802.11 Distributed Coordination Function

        ( Ping Zhong ),( Jianghong Shi ),( Yuxiang Zhuang ),( Huihuang Chen ),( Xuemin Hong ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.2

        To improve the accuracy and enhance the applicability of existing models, this paper proposes a generalized Markov chain model for IEEE 802.11 Distributed Coordination Function (DCF) under the widely adopted assumption of ideal transmission channel. The IEEE 802.11 DCF is modeled by a two dimensional Markov chain, which takes into account unsaturated traffic, backoff freezing, retry limits, the difference between maximum retransmission count and maximum backoff exponent, and limited buffer size based on the M/G/1/K queuing model. We show that existing models can be treated as special cases of the proposed generalized model. Furthermore, simulation results validate the accuracy of the proposed model.

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        An Improved Contention Access Mechanism for FPRP to Increase Throughput

        Qi Yang,Yuxiang Zhuang,Jianghong Shi 한국전자통신연구원 2013 ETRI Journal Vol.35 No.1

        Five-phase reservation protocol (FPRP) is a contentionbased media access control protocol for wireless ad hoc networks. FPRP uses a five-phase reservation process to establish slot assignments based on time division multiple access. It allows a node to reserve only one slot in an information frame. Once a node has reserved a slot, it will cease contending for other slots. As a result, there may be less contending nodes in the remaining slots, so the time slots in an information frame are not fully used by FPRP. To improve time slot utilization, this paper proposes an improved pseudo-Bayesian algorithm, based on which an improved contention access mechanism for FPRP is proposed, in which nodes are allowed to contend for more than one slot in a reservation frame according to a certain probability/priority. Simulation results indicate that the proposed mechanism performs better than FPRP in time slot utilization and hence the network throughput under various scenarios.

      • Co-DDTMA : Cooperative Distributed TDMA for Vehicular Networks

        Zhen Chen,Zhengyu Liu,Jianghong Han,Songhua Hu,Yang Lu 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.2

        In recent years, Vehicular Ad Hoc Networks (VANET) has experienced a rapid development due to the advancement of wireless communication technologies, and now emerges as a promising way to provide road safety, traffic efficiency and infotainment applications. However, it is a challenge to design a reliable and efficient Medium Access Control (MAC) protocol for VANET due to its frequent topology changes and unreliable wireless links. Cooperative communication, on the other hand, can enhance the reliability of wireless links by exploiting the broadcast nature of the wireless communication. A cooperative scheme for MAC is proposed for VANET in this paper, referred to as Cooperative Distributed TDMA (Co-DTDMA). In the Co-DTDMA, neighboring nodes utilize its idle slots for cooperatively retransmitting a packet which has failed to reach the destination. Since the cooperative retransmission is conducted in node's own idle slot, the proposed scheme does not interrupt the normal transmission. Both theoretical analysis and simulation results demonstrate that the proposed scheme greatly increases the probability of successful packet transmission and decreases the packet transmission delay.

      • KCI등재

        Feasibility Study of Radiation Dose Reduction in Adult Female Pelvic CT Scan with Low Tube-Voltage and Adaptive Statistical Iterative Reconstruction

        Xinlian Wang,Wen He,Jianghong Chen,Zhihai Hu,Liqin Zhao 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.5

        To evaluate image quality of female pelvic computed tomography (CT) scans reconstructed with the adaptive statistical iterative reconstruction (ASIR) technique combined with low tube-voltage and to explore the feasibility of its clinical application. Ninety-four patients were divided into two groups. The study group used 100 kVp, and images were reconstructed with 30%, 50%, 70%, and 90% ASIR. The control group used 120 kVp, and images were reconstructed with 30% ASIR. The noise index was 15 for the study group and 11 for the control group. The CT values and noise levels of different tissues were measured. The contrast to noise ratio (CNR) was calculated. A subjective evaluation was carried out by two experienced radiologists. The CT dose index volume (CTDIvol) was recorded. A 44.7% reduction in CTDIvol was observed in the study group (8.18 ± 3.58 mGy) compared with that in the control group (14.78 ± 6.15 mGy). No significant differences were observed in the tissue noise levels and CNR values between the 70% ASIR group and the control group (p = 0.068–1.000). The subjective scores indicated that visibility of small structures, diagnostic confidence, and the overall image quality score in the 70% ASIR group was the best, and were similar to those in the control group (1.87 vs. 1.79, 1.26 vs. 1.28, and 4.53 vs. 4.57; p = 0.122–0.585). No significant difference in diagnostic accuracy was detected between the study group and the control group (42/47 vs. 43/47, p = 1.000). Low tube-voltage combined with automatic tube current modulation and 70% ASIR allowed the low CT radiation dose to be reduced by 44.7% without losing image quality on female pelvic scan.

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