Permanent magnet temperature estimation of high power density permanent magnet synchronous machines by considering magnetic saturation

Jian Gao,Chengxu Li,Wenjuan Zhang,Shoudao Huang 전력전자학회 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.12

This paper develops a method for permanent magnet (PM) temperature estimation in high power density permanent magnet synchronous machines (PMSMs) by considering magnetic saturation. Most of the previous methods in the literature are based on unsaturation. In this paper, the temperature estimation method of PMs is improved by adding a saturation coefficient. Once a machine is assembled, the inner and outer PM surfaces cannot be seen. Thus, it is impossible to realize visualization measurement of the permanent magnet temperature distribution. In this case, temperature sensors attached to the PM cam be used. However, the cost and robustness need to be considered. Therefore, in this paper, by solving a magnetic–thermal coupling finite element model, the temperature field distribution of a high power density PMSM is obtained. Then, an experimental platform is built to verify the model. Finally, the model is used to verify the reliability of the modified estimation method.

Polymorphisms in XRCC1 Gene, Alcohol drinking, and Risk of Colorectal Cancer: a Case-control Study in Jiangsu Province of China

Gao, Chang-Ming,Ding, Jian-Hua,Li, Su-Ping,Liu, Yan-Ting,Cao, Hai-Xia,Wu, Jian-Zhong,Tang, Jin-Hai,Tajima, Kazuo Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

To evaluate the relationship between alcohol drinking, XRCC1 codon 194 and 399 polymorphisms and risk of colorectal cancer, we conducted a case-control study with 315 colorectal cancer cases (105 colon, 210 rectal) and 439 population-based controls in Jiangsu Province of China. The XRCC1 codon 194 and 399 genotypes were identified using polymerase chain reaction and restrictrion fragment length polymorphism methods (PCR-RFLP). A structured questionnaire was used to elicit detailed information. Odds ratios (ORs) were estimated with an unconditional logistic model. In this study no significant differences were observed among the studied groups with regard to the genotype distribution of the XRCC1 codons 194 and 399 and the risk of colorectal cancer did not appear to be significantly influenced by genotype alone, whereas alcohol consumption showed a positive association (P for trend <0.01). When combined effects of XRCC1 polymorphisms and alcohol consumption were analyzed, we found that the 194Trp or 399Gln alleles further increased the colorectal cancer risk due to high alcohol intake. These findings support the conclusion that colorectal cancer susceptibility may be altered by gene-environment interactions.

A putative pathogen-resistant regulatory pathway between MicroRNAs and candidate target genes in maize

Jian Gao,Mao Luo,Chun Zhang,Hua Peng,Haijian Lin,Yaou shen,Maojun Zhao,Guangtang Pan,Zhiming Zhang 한국식물학회 2015 Journal of Plant Biology Vol.58 No.4

MicroRNAs (miRNAs) are a family of small non-coding RNAs that, in most cases, negatively regulate gene expression at the post-transcriptional level. Plant miRNAs have been implicated in developmental processes and adaptation to environmental stress including biotic and abiotic stresses. Here, we report a comprehensive analysis of miRNAs and associated target genes under banded leaf and sheath blight (BLSB) stress caused by R. solani in maize. Eight differentially expressed miRNAs were randomly selected from deep sequencing results and validated by qRT-PCR together with their putative target genes, most of which are transcription factors as well as metabolic genes involved in auxin signaling. The results revealed that majorities of the analyzed miRNAs show an inverse correlation with their corresponding predicted target genes. In addition, a putative regulatory network of miRNAs-mRNAs responsive to R. solani was constructed. This study provides insight into the regulatory functions of miRNAs, thereby expanding our knowledge of the molecular mechanisms of pathogen resistance.

SKEW CYCLIC CODES OVER F_p + vF_p

Gao, Jian The Korean Society for Computational and Applied M 2013 Journal of applied mathematics & informatics Vol.31 No.3

In this paper, we study a special class of linear codes, called skew cyclic codes, over the ring $R=F_p+vF_p$, where $p$ is a prime number and $v^2=v$. We investigate the structural properties of skew polynomial ring $R[x,{\theta}]$ and the set $R[x,{\theta}]/(x^n-1)$. Our results show that these codes are equivalent to either cyclic codes or quasi-cyclic codes. Based on this fact, we give the enumeration of distinct skew cyclic codes over R.

Growth Hormone 1 T1663A Polymorphism, Recreational Physical Activity and BMI, and Breast Cancer Risk in Chinese Women

Gao, Chang-Ming,Ding, Jian-Hua,Wu, Jian-Shong,Cao, Hai-Xia,Li, Su-Ping,Liu, Yan-Ting,Tang, Jin-Hai,Tajima, Kazuo Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.13

To evaluate the relationship between the growth hormone 1 (GH1) T1663A polymorphism, recreational physical activity and body mass index (BMI) with reference to breast cancer, we conducted a case-control study with 669 cases of breast cancer and 682 population-based controls in Jiangsu Province, China. A structured questionnaire was used to elicit detailed information. All subjects completed an in-person interview. GH1 genotypes were identified using PCR-RFLP methods. Odds ratios (ORs) were estimated with an unconditional logistic model. The distribution of GH1 genotypes was not significantly different between controls and cases ($x^2$=2.576, P=0.276). Results of stratified analysis by the participation status of the recreational physical activity showed that the persons with GH1 A allele were at a decreased risk of breast cancer (adjusted-OR=0.66; 95% CI, 0.50-0.87) only among inactive individuals. Stratified analysis by BMI showed that the genotype A/A was associated with a decreased risk of breast cancer only among individuals of the BMI <25 (adjusted-OR=0.80; 95% CI, 0.66-0.98). The findings of this study suggest that recreational physical activity and BMI may modify any association between the GH1 T1663A polymorphism and breast cancer risk.

Inhibition of Indoleamine 2,3-Dioxygenase Enhances the Therapeutic Efficacy of Immunogenic Chemotherapeutics in Breast Cancer

Jian Gao,Fusheng Deng,Weidong Jia 한국유방암학회 2019 Journal of breast cancer Vol.22 No.2

Purpose: Breast cancer has become a major public health threat in the current society. Anthracycline doxorubicin (DOX) is a widely used drug in breast cancer chemotherapy. We aimed to investigate the immunogenic death of breast tumor cells caused by DOX, and detect the effects of combination of DOX and a small molecule inhibitor in tumor engrafted mouse model. Methods: We used 4T1 breast cancer cells to examine the anthracycline DOX-mediated immunogenic death of breast tumor cells by assessing the calreticulin exposure and adenosine triphosphate and high mobility group box 1 release. Using 4T1 tumor cell-engrafted mouse model, we also detected the expression of indoleamine 2,3-dioxygenase (IDO) in tumor tissues after DOX treatment and further explored whether the specific small molecule IDO1 inhibitor NLG919 combined with DOX, can exhibit better therapeutic effects on breast cancer. Results: DOX induced immunogenic cell death of murine breast cancer cells 4T1 as well as the upregulation of IDO1. We also found that treatment with NLG919 enhanced kynurenine inhibition in a dose-dependent manner. IDO1 inhibition reversed CD8+ T cell suppression mediated by IDO-expressing 4T1 murine breast cancer cells. Compared to the single agent or control, combination of DOX and NLG919 significantly inhibited the tumor growth, indicating that the 2 drugs exhibit synergistic effect. The combination therapy also increased the expression of transforming growth factor-β, while lowering the expressions of interleukin-12p70 and interferon-γ. Conclusion: Compared to single agent therapy, combination of NLG919 with DOX demonstrated better therapeutic effects in 4T1 murine breast tumor model. IDO inhibition by NLG919 enhanced the therapeutic efficacy of DOX in breast cancer, achieving synergistic effect.

Causing Troubles Elsewhere: The Shining Path and Its International Networks, 1980-1993

Jian Gao 한국라틴아메리카학회 2021 라틴아메리카연구 Vol.34 No.1

As a Maoist organization, the Shining Path inflicted terror and violence in Peru throughout the 1980s and early 1990s. Facing strong domestic resistance and vehement international condemnation, this militant group was never able to establish a communist regime in Peru as its leader Abimael Guzmán had envisioned. With little domestic support and amid frequent international denouncements, the Shining Path looked beyond the Peruvian borders for trouble and capitalized on its transnational connections to enhance its survival. Its global networks spanned the Americas, Europe, and even reached to North African countries like Libya, which lacked connections to Peru or communist countries. While the Shining Path was unable to create a massive communist regime as it wished, it did, however, generate fear and violence within Peru and beyond. From this perspective, the organization altered its strategic political goal to the process goal of effecting chaos and fear among the global communities. Ironically, the supposed allies of Shining Path, according to the Maoist ideology, actually turned against the communist organization-peasants from rural Peru resented the disruption of their lives caused by Shining Path, while China, the cradle of Maoism, along with the Soviet Union and Cuba, condemned the guerrillas as terrorists. By examining the expansive transnational sources generated by the Foreign Broadcast Information Service of the Central Intelligence Agency (CIA) and the official newspaper of the Chinese government, Renmin Ribao, this paper contributes to the recent and growing historiography that has analyzed diverse political movements in Latin America beyond their immediate geographical origins.

Eliminating the Third Harmonic Effect for Six Phase Permanent Magnet Synchronous Generators in One Phase Open Mode

Jian Liu,Gui-jie Yang,Yong Li,Hong-wei Gao,Jian-yong Su 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.1

To insure stable operation and eliminate twice torque ripple, a topology for a six phase permanent magnet synchronous generator (SP-PMSG) with a neutral point connected together was analyzed in this paper. By adopting an extended transformation matrix, the mathematic model of the space vector control was established. The voltage and torque equations were deduced while considering the third harmonic flux and inductance. In addition, the suppression third harmonic method and the closed loop control strategy were proposed. A comparison analysis indicates that the cooper loss minimum method and the current magnitude minimum method can meet different application requirements. The voltage compensation amount for each of the methods was deduced which also takes into account the third harmonic effect. A simulation and experimental result comparison validates the consistency through theoretical derivation. It can be seen that all of the two control strategies can meet the requirements of post-fault.

Main Experiences on Recycling of Waste in South Korea

Gao Jian 한국유통과학회 2012 Asian Journal of Business Environment (AJBE) Vol.2 No.1

South Korea has made remarkable achievements and gained many experiences on waste disposal and recycling, which help our country to develop cyclic economy and construct a harmonious society. This paper summarizes the policies, regulations and specific practices on waste disposal and recycling including industrial waste and household waste in South Korea so as to provide some references for the establishment of policies related to the waste recycling in our country.

Polymorphisms in the Thymidylate Synthase Gene and Risk of Colorectal Cancer

Gao, Chang-Ming,Ding, Jian-Hua,Li, Su-Ping,Liu, Yan-Ting,Cao, Hai-Xia,Wu, Jian-Zhong,Tajima, Kazuo Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

To evaluate the relationship between polymorphisms (28 bp repeated sequences in 5'-UTR and 6-bp ins/del in 3'-UTR) in then thymidylate synthetase gene (TS) and risk of colorectal, colon and rectal cancers, we conducted a case-control study with 315 cases of colorectal cancer and 439 population-based controls in Jiangsu province, China. TS genotypes were identified using PCR.RFLP (restriction fragment length polymorphism) methods. Odds ratios (ORs) were estimated with an unconditional logistic regression model. We found that the distributions of 5'-UTR genotypes in TS were significantly different between controls and male colon cases (${\chi}^2$=8.25, P = 0.016). Compared with 3R/3R genotype, individuals with the 2R allele were at an increased risk of colon cancer (age-, BMI-, smoking- and alcohol drinking-adjusted OR=1.98, 95%CI: 1.11-3.53) among men. In ccontrast, the 6-bp ins/del polymorphism at the TS 3'- UTR did not influence risk of the colorectal, colon and rectal cancers. When combined genotypes for both TS 5'-UTR and 3'-UTR polymorphisms were evaluated, individuals with the 5'-UTR 2R allele had a OR of 3.61 (95%CI: 1.38-9.49) for colon cancer among men with the 3'-UTR .6bp/-6bp genotype. These results show that the polymorphism of the 28 bp repeated sequences in TS 5'-UTR could influence susceptibility to colon cancer and that there was a coordinated effect between TS 3'-UTR and 5'-UTR polymorphisms in increasing risk of colon cancer among Chinese men.