상아질 접착제의 미세누출에 관한 연구

손정민,최남기,김선미,양규호,박지일 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

본 연구는 여러가지 상아질 접착제들의 법랑질 변연과 상아질 변연에서의 미세누출을 비교 평가하기 위해 이루어졌다. 발거된 건전한 영구치의 협면과 설명에 5급 와동을 형성하고 형성된 50개의 와동을 무작위로 5개의 군으로 나누어 각군에 Adper™ Scotchbond™ Multi-purpose Plus Adhesive (SM; 3M ESPE. USA), Adper™ Single bond 2 (SB; 3M ESPE, USA), Clearfil™ SE Bond (SE; Kuraray Medical Inc., Japan), Adper™ Prompt™ L-Pop™ (PL; 3M ESPE, USA), G-Bond™ (GB; GC Co., Japan)를 적용하고 Filtec™ Z350 A3 (3M ESPE. USA)로 충전하였다. 시편을 37℃ 증류수에 24시간 보관한 후 5℃와 55℃에서 10초씩 1000회 열순환하고 2% methylene blue 용액을 24시간 넣어 염색한 뒤, 주수 하에 치아를 협설로 절단하여 색소의 침투 정도를 화상분석현미경을 이용하여 침투깊이를 측정한 뒤 각 군간의 미세누출 정도를 비교하여 침투깊이에 따라 0~3점으로 분류하여 다음과 같은 결과를 얻었다. 1. 범랑질 변연에서의 미세누출은 PL(0.85), SB(0.55), GB(0.50), SM(0.35), SE(0.25) 순이었으며 PL은 SM 및 SE와 통계학적으로 유의한 차이를 나타냈다(p<0.05). 2. 상아질 변연에서의 미세누출은 GB(2.10), SE(1.45), PL(1.40), SB(1.05), SM(0.70) 순이었으며 GB는 SB 및 SM과 통계학적으로 유의한 차이를 나타냈다(p<0.05). 3. 각 실험재료 군내에서 법랑질 변연에 비해 상아질 변연에서 미세누출이 더 크게 나타났으며, SE, PL, GB에서 통계학적으로 유의한 차이를 나타냈다(p<0.05). The objective of this study was to compare the microleakage of five adhesive systems in the enamel and dentin of permanent teeth. Class V cavity preparations with occlusal margins in enamel and gingival margins in dentin were prepared on both buccal and lingual surfaces of 25 extracted human molar teeth. The tested adhesives were: Adper Scotchbond Multi-purpose Plus Adhesive (SM), Adper Single bond 2 (SB), Clearfil SE Bond (SE), Adper Prompt L-Pop (pL) and G-Bond (GB). The results were as follows: 1. At the enamel margins, PL showed the highest leakage value(0.85), and others showed values of SB(0.55), GB(O.50), SM(O.35) and SE(0.25) in decreasing order. There were statistically significant differences in PL vs. SM and PL vs. SE(p<O.05). 2. At the dentin margins, GB showed the highest leakage value(2.10), and others showed values of SE(1.45), PL(1.40), SB(1.05), SM(0.70) in decreasing order. There were statistically significant differences in GB vs. SB and GB vs. SM(p<O.05). 3. Dentin margins showed high dye penetration rate than enamel margins in all material tested groups and there were statistically significant differences for SE, PL and GB.

Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats

Son, Ji-Seon,Kwon, Young-Bae The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.6

Many therapeutic roles have been proposed for sigma-1 receptor (Sig-1R), but the involvement of Sig-1R in neuropathic pain has currently not been well explored. The present study aimed to evaluate the anti-nociceptive effect of Sig-1R antagonist (BD1047) in a rat model of chronic compression of the dorsal root ganglion (CCD), which is a model of human foraminal stenosis and radicular pain. When stainless steel rods were inserted into the intervertebral foramen of lumbar vertebrae 4 and 5, the CCD developed reliable mechanical (from 3 day) and cold allodynia (from 1 day) as compared with the sham operation group. The spinal expressions of Sig-1R and phosphorylation of extracellular signal-regulated kinase (pERK) were significantly increased from day 3 to day 14 after CCD surgery, as is consistent with the manifestation of allodynia. The BD 1047 (10, 30, 100 mg/kg) administered on postoperative days 0~5 dose-dependently suppressed both the induction of allodynia and the elevation of the spinal pERK expression in a manner comparable with that of gabapentin (100 mg/kg). At 7 days post-CCD surgery, BD1047 (10, 30, 100 mg/kg) administration also produced anti-nociceptive effects on the mechanical and cold allodynia similar with those of gabapentin (100 mg/kg). Therefore, this data suggested that Sig-1R may play an important role in both the development and maintenance of CCD-induced neuropathy.

Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats

Ji Seon Son,Young Bae Kwon 대한생리학회-대한약리학회 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.6

Many therapeutic roles have been proposed for sigma-1 receptor (Sig-1R), but the involvement of Sig-1R in neuropathic pain has currently not been well explored. The present study aimed to evaluate the anti-nociceptive effect of Sig-1R antagonist (BD1047) in a rat model of chronic compression of the dorsal root ganglion (CCD), which is a model of human foraminal stenosis and radicular pain. When stainless steel rods were inserted into the intervertebral foramen of lumbar vertebrae 4 and 5, the CCD developed reliable mechanical (from 3 day) and cold allodynia (from 1 day) as compared with the sham operation group. The spinal expressions of Sig-1R and phosphorylation of extracellular signal-regulated kinase (pERK) were significantly increased from day 3 to day 14 after CCD surgery, as is consistent with the manifestation of allodynia. The BD 1047 (10, 30, 100 mg/kg) administered on postoperative days 0∼5 dose-dependently suppressed both the induction of allodynia and the elevation of the spinal pERK expression in a manner comparable with that of gabapentin (100 mg/kg). At 7 days post-CCD surgery, BD1047 (10, 30, 100 mg/kg) administration also produced anti-nociceptive effects on the mechanical and cold allodynia similar with those of gabapentin (100 mg/kg). Therefore, this data suggested that Sig-1R may play an important role in both the development and maintenance of CCD-induced neuropathy.

딥 앙상블을 이용한 딥러닝 기반의 항공 이미지 객체 탐지

박주찬(Joo-Chan Park),손성빈(Sung-Bin Son),이선훈(Seon-Hoon Lee),정준욱(Jun-Uk Jung),박용준(Yong-Jun Park),오흥선(Heung-Seon Oh) 제어로봇시스템학회 2021 제어·로봇·시스템학회 논문지 Vol.27 No.12

Object detection in aerial images is continuously studied for various purposes such as national security, disaster monitoring, and meteorological observation. It is difficult to improve recent object detection methods based on a single model using deep learning due to severe class imbalance. This paper proposes a deep ensemble method combining two models with different strengths and a class-dependent thresholding method by considering the object distribution. We demonstrate the superiority of our methods in a series of experiments. In addition, we take 1st place in both public and private scores in the Arirang satellite image AI object detection contest.

만성 족관절 외과 점액낭염 환자에서 OK-432 를 이용한 경화치료

이지혜 ( Ji Hye Lee ),허현주 ( Hyun Joo Heo ),오지윤 ( Ji Youn Oh ),장은주 ( Eun Joo Jang ),손지선 ( Ji Seon Son ) 전북대학교 의과학연구소 2014 全北醫大論文集 Vol.38 No.2

Conservative treatment on lateral malleolar bursitis is effective, but recurrence is common. Steroid injection or surgical procedure has been used for the treatment, but the recurrence rate is high. In this report, we present a case of lateral malleolar bursitis of the ankle that was treated by the injection of a sclerosant, OK-432 (Picibanil., Chugai Pharmaceutical Co, Japan) 0.03 mg. Sufficient sclerosing effect was acquired from 0.03 mg of OK-432, although the amount of OK-432 was less than previously reported. Sclerotherapy of OK-432 and active treatment for the complication can be safe and effective method of treatment for chronic lateral malleolar bursitis of the ankle.

케이지 사육시 사육밀도가 산란계의 깃털손상도, 계란품질, 혈액성상 및 스트레스 호르몬 농도에 미치는 영향

손지선(Ji Seon Son),김찬호(Chan Ho Kim),강환구(Hwan Ku Kang),김현수(Hyun Soo Kim),전진주(Jin Joo Jeon),홍의철(Eui Chul Hong),강보석(Bo Seok Kang) 한국가금학회 2020 韓國家禽學會誌 Vol.47 No.2

본 연구는 케이지 사육 시 사육밀도가 산란계의 깃털 손상도, 계란품질, 혈액성상 및 스트레스 호르몬 농도에 미치는 영향을 구명하기 위하여 수행되었다. 산란계(Hy-Line Brown) 700수를 공시하여 배터리 케이지에 750 ㎠/수 및 500 ㎠/수 사육밀도 처리구로 50 반복을 두어 32주부터 60주까지 총 28주간 실시하였으며, 사료와 물은 자유 급이 하였다. 사육밀도가 증가함에 따라 주령이 증가할수록 깃털손상도가 증가하였으며, 등과 꼬리 부위의 손상이 유의적으로 증가하였다. 계란품질(난중, Haugh unit, 난각 강도 등)은 사육밀도에 따른 처리구 간 유의적 차이는 나타나지 않았다. 또한, 혈구 성분 및 혈액 생화학 지표는 사육밀도에 의한 영향을 받지 않는 것으로 나타났다. 그러나 시험종료 시점의 혈액과 깃털 내 스트레스 호르몬인 corticosterone 농도를 분석한 결과, 500 ㎠/수 사육밀도에서 사육 시 750 ㎠ 보다 높게 나타났다. 결론적으로 케이지에서 500 ㎠/수 사육밀도 사육은 산란계의 깃털손상도를 증가시켜 부정적인 영향을 미치는 것으로 보이며, 향후 산란계의 행동과 관련된 추가 연구가 필요할 것으로 판단된다. The purpose of this study was to evaluate the effects of stocking density on feather condition, egg quality, blood parameters, and corticosterone levels of laying hens reared in conventional cages. A total of 500, 28 weeks-old Hy-Line Brown laying hens were evenly assigned to two stocking densities (750 and 500 ㎠/bird). There were 50 replicates of each treatment, each consisting of 750 ㎠/birds (n=6) or 500 ㎠/bird (n=4) birds in a cage, respectively. We observed an increase in the laying period of, the group that was assigned 500 ㎠/bird, however, this group experienced significant feather damage when compared with the group allotted 750 ㎠ bird. There was no effect of stocking densities on egg quality. These results suggest that the 500 ㎠/bird stocking density in the conventional cage can negatively affect feather condition and cause the birds to experience more stress than the group allotted 750 ㎠/bird.

반대편 눈확위신경 영역에 재발된 대상포진 1 예

손지선(Ji Seon Son),오광조(Kwang Jo Oh),이준례(Jun Rae Lee),최훈(Huhn Choe),한영진(Young Jin Han) 대한통증학회 2001 The Korean Journal of Pain Vol.14 No.2

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정황(context) 정보 추출을 위한 사용자 조사 방법의 속성 비교에 관한 연구

손지선(Son Ji-Seon),남성훈(Nam Sung-Hun),정지홍(Jung Ji-Hong) 한국디자인학회 2005 한국디자인학회 학술발표대회 논문집 Vol.2005 No.5

제품 사용의 관찰범위에 따른 사용자 행위 데이터 비교 분석에 관한 연구 : 주거공간에서의 사용자 행위 관찰 사례를 중심으로

손지선(Ji Seon Son),정지홍(Ji Hong Jung) 한국HCI학회 2006 한국HCI학회 학술대회 Vol.2006 No.2

안산시 부곡동 매입임대주택 거주자 복지욕구 조사

김지선(Kim Ji Seon),용명학(Yong Myung Hak),이은주(Lee Eun Joo),강진이(Kang Ji Ny),윤민주(Yun Min Ju),유상미(Yoo Sang Mi),성언경(Seong Eon Kyeong),안주희(An Ju Hee),홍서현(Hong Seo Hyeon),오명림(Oh Myeong Rim),손경진(Son Gyeong Jin),지 한국상담복지경영학회 2019 상담복지경영연구 Vol.- No.2

본 연구는 안산시 부곡동 지역의 현황을 파악하고 문제 및 욕구를 사정하여 향후 부곡종합사회복지관의 신규 프로그램 및 개발에 기초자료로 활용될 것이며, 부곡종합사회복지관이 지역사회 문제 및 욕구를 주민들과 함께 할 수 있는 마을공동체 허브로 변신하기 위함에 목적이 있다. 본 연구의 결과를 살펴보면, 아동을 대상으로 한 프로그램에 대한 욕구를 살펴보면, 1순위로 아동발달지원센터 참여할 의향이 44.4%, 피아노교실 참여 55.6%, 아동난타 44.4%로 나타나, 본 복지관에서는 아동발달지원센터 이용 확대를 위한 지원을 강화할 필요가 있고, 피아노 교실 및 아동난타 프로그램 및 서비스를 확대할 필요가 있는 것으로 나타났다. 청소년을 대상으로 한 프로그램에 대한 욕구를 살펴보면, 1순위로 청소년 자원봉사학교 66.7%, 명문대학 탐방 참여 44.4%, 청소년 진로체험 55.6%로 나타났다. 따라서, 본 복지관에서는 청소년 자원봉사를 위한 다양하고 전문적인 프로그램을 진행할 필요가 있다. 성인을 대상으로 한 프로그램에 대한 욕구를 살펴보면, 1순위로 동그라미 빨래방 25.7%, 취업훈련 20.0%, 2순위로 김장지원서비스 14.7%, 무료 점심 나누기 11.4%로 나타나, 본 복지관에서는 성인을 대상으로 취업훈련에 대한 프로그램 및 서비스를 강화할 필요가 있다. 노인을 대상으로 한 프로그램에 대한 욕구를 살펴보면, 1순위로 무료진료 48.8%, 김장지원서비스 47.6%로 나타나, 본 복지관에서는 노인을 대상으로 무료 진료 프로그램 및 서비스를 강화할 필요가 있고, 김장지원서비스도 확대할 필요가 있는 것으로 나타났다. This study will be used as basic data for new programs and developments of the Bugok Social Welfare Center in the future by grasping the current status of the Bugok-dong area in Ansan-si and assessing the problems and needs, and the Bugok Social Welfare Center will be able to share community problems and needs with residents. The purpose is to transform into a village community hub. Looking at the results of this study, looking at the needs of children s programs, the intention to participate in the Children s Development Support Center was 44.4%, 55.6% participating in the piano classroom, and 44.4% child hitting. It was found that there is a need to strengthen support to expand the use of support centers, and to expand piano classrooms and children s hitting programs and services. Looking at the needs of the program for young people, 66.7% of youth volunteer schools, 44.4% of participating in prestigious university visits, and 55.6% of youth career experiences were ranked first. Therefore, the welfare center needs to carry out various and specialized programs for youth volunteering. Looking at the desire for the program for adults, the first rank was circled laundry 25.7%, job training 20.0%, second rank kimjang support service 14.7%, free lunch break 11.4%. There is a need to strengthen training programs and services. Looking at the needs for programs targeted at the elderly, the number of free medical treatment was 48.8% and Kimjang support service 47.6% as the first priority. It turned out to be necessary to enlarge.