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유근종,윤지훈 國立 昌原大學校 産業技術硏究所 1999 産技硏論文集 Vol.13 No.-
Analysis of ventilation fan flow has been carried out using CFX CFD code. The ventilation fan is applied widely to enhance air flow in open space. Selection of the ventilation fan is an important factor to design air ventilation facility to control air quality. Therefore, the accurate flow analysis is required in process of proper ventilation fan selection. Detailed analysis of fan flow in open space has been performed for 4 different commercially available ventilation fan. Computed air velocities show typical jet flow characteristics. The fan flow expands up to 10m in both of lengthwise and spanwise direction. The analysis also shows that turbulent flow enhances mixing of air in the space. From the analysis, flow analysis using CFD method is found to be an effective tool to select a proper ventilation fan. However, further detailed analysis which includes mass transfer for prediction pollutant behavior is required to complete air quality analysis.
Transient diestrus-related diabetes mellitus in a dog
Ji-Houn Kang, Ah Young Kim, Mhan-Pyo Yang 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3
A 10-year-old intact female Cocker Spaniel weighing 15.3 kg presented with dysbasia. The dog had hyperglycemia and glucosuria at presentation. Neurological examination and magnetic resonance imaging on the following day indicated the onset of cervical disk disease. Four days later, the patient returned due to sudden vomiting and anorexia with severe dehydration. Abnormal laboratory findings included severe hyperglycemia with ketonuria. Plasma progesterone concentration was very high at presentation. She was hospitalized for critical care, and insulin administration with fluid therapy was initiated. Mean blood glucose concentration showed a gradual decline, and hyperglycemia with glucosuria disappeared four days after initiation of insulin therapy. This case demonstrated that high plasma progesterone concentration during diestrus can contribute to development of diabetes mellitus in intact female dogs
Acute Renal Proximal Tubular Dysfunction in Two Dogs Associated with Grapes Ingestion
Ji-Houn Kang,Dongwoo Chang,Byeongwoo Ahn,Ki-Jeong Na,Mhan-Pyo Yang 한국실험동물학회 2006 Laboratory Animal Research Vol.22 No.4
Acute renal failure caused by renal proximal tubular dysfunction was diagnosed in two dogs who had ingested grapes. In both cases serum biochemistry revealed severe azotemia, hyperphosphatemia, and hyponatremia. Normoglycemic glycosuria was observed, and the percentage of amino acids that were reabsorbed was reduced. Histopathological examination of the kidneys demonstrated diffuse tubular epithelial degeneration and necrosis manifested by nuclear pyknosis, and cytoplasmic vacuolation. The damage to the proximal tubules was more severe than to the distal or collecting tubules. These findings indicate that grapes ingestion in dogs may induce severe proximal tubular dysfunction, which in turn progresses to renal failure.
Kang, Ji-Houn,Lee, Geun-Shik,Jeung, Eui-Bae,Yang, Mhan-Pyo Cambridge University Press 2007 The British journal of nutrition Vol.97 No.1
<P><I>Trans</I>-10, <I>cis</I>-12-conjugated linoleic acid (t10c12-CLA) has been shown to alter immune function. PPARγ has been shown to potentially play an important role in regulating inflammatory and immune responses by modulating the activity of monocytes and macrophages. Previous studies have indicated that the phagocytic capacity of porcine peripheral blood polymorphonuclear cells (PMN) was enhanced by the culture supernatant fraction from t10c12-CLA-stimulated porcine peripheral blood mononuclear cells (PBMC) but not by t10c12-CLA itself. In the present study, we examined the effects of t10c12-CLA on PPARγ and TNF-α expression of porcine PBMC and the phagocytic capacity of PMN. t10c12-CLA increased TNF-α mRNA expression and production by PBMC. The phagocytic capacity of porcine PMN was enhanced by either culture supernatant fraction from PBMC treated with t10c12-CLA or recombinant porcine (rp) TNF-α. Anti-rpTNF-α polyclonal antibody inhibited the enhancement of PMN phagocytic capacity. t10c12-CLA also up regulated PPARγ mRNA expression in porcine PBMC. Bisphenol A diglycidyl ether, a PPARγ antagonist, not only completely negated the t10c12-CLA-stimulating effects on TNF-α expression and production by porcine PBMC, but also decreased the enhancement of PMN phagocytic capacity by the t10c12-CLA-stimulated porcine PBMC culture supernatant fraction. These results suggest that t10c12-CLA has an immunostimulating effect on porcine PMN phagocytic capacity, which is mediated by TNF-α from PBMC via a PPARγ-dependent pathway.</P>
이지훈 ( Ji Houn Lee ) 한국과학철학회 2005 과학철학 Vol.8 No.2
In the light of some ontological basis for the contemporary sciences, the ontological interpretation on the relation between the Whole and the Individual would be one of the important issues. Firstly, we defined the Whole as a mode, acting like a unity of causal power on to the parts, whose main properties would be the subjectivity and historicity. And the latter relates to concept of event : a crucial and non-deterministic change depending on a whole-context. This concept reveals some essential figures of the relation between the Whole and the Individual. After having redefined several terms, such as the potential and actual, we classified the event into two categories. The one relating to an individualization or an actualization, and the other to becoming of the whole which means the radical change of the whole triggered by a `part`. Finally we claimed two kinds of the events differ in perspective but have a common ontological basis.