Channel Characteristics of Indoor Wireless Infrared Communication System Due to Different Transceiver Conditions

Chuan Peng(팽천),Zan Wang(왕잔),Ji Do Kim(김지도),Jae Kyung Pan(반재경) 한국통신학회 2008 韓國通信學會論文誌 Vol.33 No.2A

In this paper, we consider the diffuse type of indoor wireless optical communication (WOC) system. To find the channel characteristics of indoor wireless infrared communication system, we investigate the simulation process to get the impulse response of diffuse type and analyze the scenario of the indoor structure which we have built. The simulation results of the impulse response include power ratio and time delay due to bounce times. We get and discuss the receiving power distribution according to six configurations which have different transmitter and receiver positions and reflection coefficients of the indoor structure assumed. The results of this paper are useful to design the indoor wireless optical communication systems.

XPC 939A>C and 499C>T Polymorphisms and Skin Cancer Risk: a Meta-analysis

Ji, Geng,Lin, Yuan,Cao, Song-Yu,Li, Luo-Zhu,Chen, Xin-Long,Sun, Bu-Mei,Chen, Chuan-Jun,Ma, Hong-Xia Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

The xeroderma pigmentosum complementation group C gene (XPC) has been identified as important for repairing UV-related DNA damage. Some subtle changes in this gene may impair repair efficiency and influence susceptibility to human cancers, including skin cancer. Two polymorphisms in XPC, 939A>C (rs2228001) and 499C>T (rs2228000), are considered to have possible associations with the risk of skin cancer, but the reported results have been inconsistent. Here we performed a meta-analysis of the available evidence regarding the relationship between these two polymorphisms and the risk of skin cancer. All relevant studies were searched using PubMed, Embase and Web of Science before February 2012. A total of 8 case-control studies were included in this analysis, and no convincing associations between the two polymorphisms and risk of skin cancer were observed in any of the genetic models. Stratified analyses by skin cancer type also did not detect significant associations in any subgroup. This meta-analysis suggested that the XPC 939A>C and 499C>T polymorphisms may have little involvement in susceptibility to skin cancer.

Channel Characteristics of Indoor Wireless Infrared Communication System Due to Different Transceiver Conditions

Chuan Peng,Zan Wang,Ji Do Kim,Jae Kyung Pan 한국통신학회 2007 한국통신학회 학술대회논문집 Vol.2007 No.11

Inverse Optimal Adaptive Stochastic Gain Assignment for a Class of Nonlinear Systems with Markovian Jump

Chuan-Rui Wang,Xing-Hu Wang,Hai-Bo Ji 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.4

This paper deals with the inverse optimal adaptive stochastic gain assignment problem for a class of Markovian jump nonlinear systems with constant unknown parameters. The Wiener noises have bounded but unknown covariance. It is shown that a sufficient condition to solve this problem is the existence of a Lyapunov function for a corresponding auxiliary system. By employing backstepping technique and common Lyapunov function method, an adaptive control law is designed, which solves this problem for a class of Markovian jump nonlinear systems in strict-feedback form. A numerical example is given to illustrate the theoretical analysis result.

Effect of Xeroderma Pigmentosum Complementation Group F Polymorphisms on Gastric Cancer Risk and Associations with H.pylori Infection

Zhang, Ji-Shun,Zhang, Chuan,Yan, Xue-Yan,Yuan, Zhi-Fang,Duan, Zhuo-Yang,Gao, Hui Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

We conducted a hospital case-control study by genotyping four potential functional single nucleotide polymorphisms (SNPs) to assess the association of Xeroderma pigmentosum complementation group F (XPF) with gastric cancer susceptibility, and role of XPF polymorphisms in combination with H.pylori infection in risk definition. A total of 331 patients with gastric cancer and 355 controls were collected. Four SNPs of XPF, rs180067, rs1799801, rs2276466 and rs744154, were genotyped by Taqman real-time PCR method with a 7900 HT sequence detector system. The gastric cancer patients were more likely to have smoking habit, a family history of cancer and H.pylori infection. We did not find any significant difference in the genotype distributions of XPF rs180067, rs1799801, rs2276466 and rs744154 between cases and controls. However, multivariate logistic analysis showed a non-significant decreased risk in patients carrying rs180067 G allele, rs1799801 T allele or rs2276466 T allele genotypes. A non-significant increased risk of gastric cancer was found in individuals carrying the rs744154 GG genotype. Stratification by H.pylori infection and smoking was not significantly different in polymorphisms of XPF rs180067, rs1799801, rs2276466 and rs744154. The four XPF SNPs did not show significant interaction with H.pylori infection and smoking status (P for interaction was 0.35 and 0.18, respectively). Our study indicated that polymorphisms in rs180067, rs1799801, rs2276466 and rs744154 may affect the risk of gastric cancer but further large sample size studies are needed to validate any association.

Plant U-Box40 Mediates Degradation of the Brassinosteroid-Responsive Transcription Factor BZR1 in Arabidopsis Roots

Kim, Eun-Ji,Lee, Se-Hwa,Park, Chan-Ho,Kim, So-Hee,Hsu, Chuan-Chih,Xu, Shouling,Wang, Zhi-Yong,Kim, Seong-Ki,Kim, Tae-Wuk American Society of Plant Biologists 2019 The Plant cell Vol.31 No.4

<P>Brassinosteroid signaling tightly controls the degradation of the transcription factor BRASSINAZOLE RESISTANT1 specifically in roots.</P><P>Brassinosteroid (BR) regulates a wide range of physiological responses through the activation of BRASSINAZOLE RESISTANT1 (BZR1), whose activity is tightly controlled by its phosphorylation status and degradation. Although BZR1 appears to be degraded in distinct ways in response to different hormonal or environmental cues, little is known about how BR signaling regulates its degradation. Here we show that the BR-regulated U-box protein PUB40 mediates the proteasomal degradation of BZR1 in a root-specific manner in Arabidopsis (<I>Arabidopsis thaliana</I>). BZR1 levels were strongly reduced by plant U-box40 (PUB40) overexpression, whereas the <I>pub39 pub40 pub41</I> mutant accumulated much more BZR1 than wild type in roots. The <I>bzr1</I>-<I>1D</I> gain-of-function mutation reduced the interaction with PUB40, which suppressed PUB40-mediated BZR1 degradation in roots. The cell layer-specific expression of <I>PUB40</I> in roots helps induce selective BZR1 accumulation in the epidermal layer. Both BR treatment and loss-of-function of PUB40 expanded BZR1 accumulation to most cell layers. In addition, BZR1 accumulation increased the resistance of <I>pub39 pub40 pub41</I> to low inorganic phosphate availability, as observed in <I>bzr1</I>-<I>1D</I>. BRASSINOSTEROID-INSENSITIVE2-induced phosphorylation of PUB40, which mainly occurs in roots, gives rise to BZR1 degradation through enhanced binding of PUB40 to BZR1 and PUB40’s stability. Our results suggest a molecular mechanism of root-specific BZR1 degradation regulated by BR signaling.</P>

Adaptive Target Synchronization for Wireless Sensor Networks with Markov Delays and Noise Perturbation

Wuneng Zhou,Chuan Ji,Jinping Mou,Dongbing Tong,Yan Gao 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.5

This article focuses on the problem of adaptive target synchronization for the Wireless Sensor Networks (WSNs). By applying the LaSalle-type invariance principle and the M-matrix approach for stochastic differential delay equations with Markovian switching, several sufficient conditions to ensure adaptive target synchronization and adaptive exponential target synchronization in pth moment for WSNs with Markov delays and stochastic noises are derived. We further investigate the adaptive exponential target synchronization in probabilistic sense for the WSNs and obtain the almost sure adaptive exponential target synchronization. Via the adaptive feedback control techniques, some suitable parameters update laws are attained. We finally show some numerical simulations to illustrate the effectiveness of the results derived in this paper.

Proangiogenic functions of an RGD-SLAY-containing osteopontin icosamer peptide in HUVECs and in the postischemic brain

이한비,Yin-Chuan Ji,김승우,김일두,이혜경,이자경 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

Osteopontin (OPN) is a phosphorylated glycoprotein secreted into body fluids by various cell types. OPN contains arginine-glycineaspartate (RGD) and serine-leucine-alanine-tyrosine (SLAY) motifs that bind to several integrins and mediate a wide range of cellular processes. In the present study, the proangiogenic effects of a 20-amino-acid OPN peptide (OPNpt20) containing RGD and SLAY motifs were examined in human umbilical vein endothelial cells (HUVECs) and in a rat focal cerebral ischemia model. OPNpt20 exerted robust proangiogenic effects in HUVECs by promoting proliferation, migration and tube formation. These effects were significantly reduced in OPNpt20-RAA (RGD-4RAA)-treated cells, but only slightly reduced in OPNpt20-SLAA (SLAY-4SLAA)- treated cells. Interestingly, a mutant peptide without both motifs failed to induce these proangiogenic processes, indicating that the RGD motif is crucial and that SLAY also has a role. In OPNpt20-treated HUVEC cultures, AKT and ERK signaling pathways were activated, but activation of these pathways and tube formation were suppressed by anti-αvβ3 antibody, indicating that OPNpt20 stimulates angiogenesis via the αvβ3-integrin/AKT and ERK pathways. The proangiogenic function of OPNpt20 was further confirmed in a rat middle cerebral artery occlusion model. Total vessel length and vessel densities were markedly greater in OPNpt20-treated ischemic brains, accompanied by induction of proangiogenic markers. Together, these results demonstrate that the 20-amino-acid OPN peptide containing RGD and SLAY motifs exerts proangiogenic effects, wherein both motifs have important roles, and these effects appear to contribute to the neuroprotective effects of this peptide in the postischemic brain.

Effects of Doctor-patient Communication on Quality of Life among Breast Cancer Patients in Southern China

Zhou, Qin,Shen, Ji-Chuan,Liu, Ying-Zhi,Lin, Guo-Zhen,Dong, Hang,Li, Ke Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

Objective: This study aimed to determine effects of doctor-patient communication on the quality of life among breast cancer survivors in 16 communities in southern China. Methods: Multistage random sampling was to use to recruit 260 females from the Guangzhou Cancer Registry Database who were diagnosed with breast cancer. A questionnaire provided data on the doctor-patient communication (including the doctor's attitude, the patient's participation with the medical decision and information about the disease) and QOL (quality of life), as measured using FACT-B. Univariate analysis, non-conditional logistic regression was used to evaluate the associations between the doctor-patient communication and QOL. Results: Females who received good attitudes from doctors demonstrated higher FACT-B (OR=4.65, 95% CI: 1.68-12.86), social well-being (OR=5.88, 95% CI: 2.16-16.05), emotional well-being (OR=4.77, 95% CI: 1.92-11.88), and functional well-being ((OR=5.26, 95% CI: 1.90-14.52) compared to the females who encountered worse attitudes from their doctor, adjusting for age, education, marriage, employment, family income, years since diagnosis, TNM stage, radiation therapy, chemotherapy and side effects, particularly when the TNM stage was 0-II and the patients exhibited no side effects. Regardless of the length of time after diagnosis, doctors' good attitudes resulted in higher QOL scores. Conclusions: This study demonstrated that the doctor-patient communication has a significant association with the QOL of breast cancer survivors, mainly dependent on the doctors' attitude. Effective intervention is required to develop optimal doctor-patient communication.

Simultaneous treatment with sorafenib and glucose restriction inhibits hepatocellular carcinoma in vitro and in vivo by impairing SIAH1-mediated mitophagy

Zhou Jing,Feng Ji,Wu Yong,Dai Hui-Qi,Zhu Guang-Zhi,Chen Pan-Hong,Wang Li-Ming,Lu Guang,Liao Xi-Wen,Lu Pei-Zhi,Su Wen-Jing,Hooi Shing Chuan,Ye Xin-Pin,Shen Han-Ming,Peng Tao,Lu Guo-Dong 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Transarterial chemoembolization (TACE) is the first-line treatment for unresectable intermediate-stage hepatocellular carcinoma (HCC). It is of high clinical significance to explore the synergistic effect of TACE with antiangiogenic inhibitors and the molecular mechanisms involved. This study determined that glucose, but not other analyzed nutrients, offered significant protection against cell death induced by sorafenib, as indicated by glucose deprivation sensitizing cells to sorafenib-induced cell death. Next, this synergistic effect was found to be specific to sorafenib, not to lenvatinib or the chemotherapeutic drugs cisplatin and doxorubicin. Mechanistically, sorafenib-induced mitophagy, as indicated by PINK1 accumulation, increased the phospho-poly-ubiquitination modification, accelerated mitochondrial membrane protein and mitochondrial DNA degradation, and increased the amount of mitochondrion-localized mKeima-Red engulfed by lysosomes. Among several E3 ubiquitin ligases tested, SIAH1 was found to be essential for inducing mitophagy; that is, SIAH1 silencing markedly repressed mitophagy and sensitized cells to sorafenib-induced death. Notably, the combined treatment of glucose restriction and sorafenib abolished ATP generation and mitophagy, which led to a high cell death rate. Oligomycin and antimycin, inhibitors of electron transport chain complexes, mimicked the synergistic effect of sorafenib with glucose restriction to promote cell death mediated via mitophagy inhibition. Finally, inhibition of the glucose transporter by canagliflozin (a clinically available drug used for type-II diabetes) effectively synergized with sorafenib to induce HCC cell death in vitro and to inhibit xenograft tumor growth in vivo. This study demonstrates that simultaneous treatment with sorafenib and glucose restriction is an effective approach to treat HCC, suggesting a promising combination strategy such as transarterial sorafenib-embolization (TASE) for the treatment of unresectable HCC.