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      • 신경교 세포 기원 종양의 조직 병리와 p53 Protein 발현과의 관계

        류태희,최정목,강대영 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.1

        The p53 gene is one of the most extensively investigated tumor suppressor genes. Several neoplasms have been thoroughly investigated for altered p53 gene expression, including lung, breast, and colorectal cancers, but the studies of neuroglial tumors are rare. Immunohistochemically, we demonstrated p53 protein expression in 40 cases of 156 central nervous system tumors, which were collected from Jan. 1989 to June 1993 at the department of anatomical pathology, Chungnam National University hospital. The results are as follows; 1. The incidence of gliomas(25.6%) was the highest in brain tumors, followed by meningomas(16.7%), pituitary adenomas(15.4%), neurilemomas(14.1%) and metastatic tumors(9.6%). 2. The incidence of gliomas in males was slightly higher than in females(M:F = 1.1: 1). Gliomas were distributed among all age groups, and the mean age was 35.3 years. 3. The positivity of p53 protein expression was the highest in glioblastoma multiforme(75.0%), followed by anaplastic astrocytoma(66.7%), low grade astrocytoma(30.0%), oligodendroglioma(20.0%), and ependymoma(16.1%). 4. The p53 index(No. of p53 protein positive cells/No. of total cells) was 68.7 in the glioblastomamultiforme in the original tumor, while 91.8 in the recurrent glioblastoma multiforme. The results suggest that there is some correlation between the degree of the histopathologic differentiation in neurogical tumors and the p53 protein expression. In addition, the p53 protein detection may provide a clue in the identification of malignant progression in neuroglial tumors.

      • KCI등재후보

        해수유동모델 결과의 3차원 가시화를 위한 GUI 구현

        최우정,박성은,이원찬,구준호,서영상,김태현 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.3

        해수유동모델 결과를 3차원적으로 가시화하기 위한 그래픽 유저 인터페이스를 구축하는 과정에서 지리정보시스템(GIS) 기술을 활용하였다. 연안역 관리에서 GIS 기법은 산재되어 있는 방대한 자료들을 저장하고 이를 3차원으로 가시화하는 기능을 제공하며 해석적, 통계적, 모델링 도구로써 주어진 상황에 적합한 데이터 변환이 가능하도록 해준다. 해수유동모델은 개방경계에서 조석, 바람, 수온, 염분, 강물 유입 및 태양복사 등과 같은 모델입력값을 부여함으로써 구동되며 대상해역은 진해만으로 하였다. 녈 연구에서는 국산 GIS 소프트웨어인 GeoMania (v2.5)를 사용하여 진해만을 대상으로 시뮬레이션된 해수유동모델 결과의 3차원 가시화 모듈을 구축하였다. This study presents an application of GIS technologies to construct the graphic user interface for 3-dimensional exhibition of the results obtained by ocean hydrodynamic model. In coastal management studies, GIS provide a receptacle for scattered data from diverse sources and an improvement of the 3D visualization of such data. Within the frame of a GIS a variety of analytical, statistical and modeling tools can be applied to transform data and make them suitable for a given application. A 3D hydrodynamic model was driven by time-dependent external forcing such as tide, wind velocity, temperature, salinity, river discharge, and solar radiation under the open boundary condition. The Jinhae bay was selected as a case study. Here, we have used GeoMania v2. 5 GIS software and its 3D Analyst extension module to visualize hydrodynamic model result that were simulated around the Jinhae bay.

      • 회전체 균열과 진동신호와의 상관관계 연구

        김정태,조성호 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.1

        Application of instantaneous frequency analysis is implemented to investigate a crack inside a rotor. As important parameters of rotor crack detection, rotation speed and gravitational effect are studied. During the study, maximun crack size is increased up to 5% of the rotor radius and the rotating speed is changed from 40% to 50% and 60% of the critical frequency. The investigated results are as follow; (1) At 50 % of critical frequency, harmonic component of 2x is most sensitive to a crack. Also, the output of the instataneous frequency analysis shows stable pattern, whether it is in gravitation or horezental direction. (2) At a sub-critical speed, the amplitude of 2x component is larger than that of 1x. Also, the signal in gravitation direction becomes stable compared to the horizontal direction. Therefore, the vibration monitoring for a rotor craction crack detection is recommended to use the signal measured in the gravitational direction.

      • 페라이트 도금법으로 제작된 Ni_(x)Fe_(3-x)O₄박막의 자외선차단 효과에 대한 연구

        하태욱,이용희,최종정,차정원 한국공업화학회 2003 응용화학 Vol.7 No.2

        Nickel-ferrite Ni_(x)Fe_(3-x)O₄ thin film was fabricated by ferrite plating method in order to make sunglass which intercept ultraviolet ray and electromagnetic field. The transmittance of nickel-ferrite Ni_(x)Fe_(3-x)O₄ thin film is down clearly below 400㎚. And it shows that the nickel-ferrite thin film of x=0.09 in nickel composition rate was intercepted ultraviolet ray. We expect that sunglass coated with Ni_(x)Fe_(3-x)O₄ thin film will use for interception of ultraviolet ray and electromagnetic field.

      • 멀티 플랫폼상의 컴포넌트 연동 방법 연구

        김정현,김태웅,김태공,전순미,최항묵 인제대학교 2002 仁濟論叢 Vol.17 No.1

        소프트웨어 개발 방법론이 객체지향개발 방법론(OOD : Object Oriented Development)에서 점차 컴포넌트 기반 개발 방법론(CBD : Component Based Development)으로 변화되어 가는 추세이다. 경험이 많은 개발자에 의해 개발된 컴포넌트는 소프트웨어 재사용이 뛰어나고, 이미 많은 곳에서 사용 중이므로 안정성 및 신뢰성이 인정된다. 하지만 개발언어와 플랫폼의 특성에 따라 컴포넌트의 조합에 있어 어려움이 따른다. 이에 본 연구에서는 HTTP와 XML을 이용하여 개발언어와 플랫폼에 독립적으로 컴포넌트를 조합할 수 있는 방안에 대해 연구하고 기존의 컴포넌트에 HTTP와 XML을 이용한 컴포넌트 호출을 보인다.

      • 돼지 적리에 대한 Sedecamycin의 야외적용 효과

        金泰鐘,朴政文 건국대학교 동물자원연구센터 1991 動物資源硏究誌 Vol.16 No.-

        This experiment was carried out to study the benificial, prophylatic and threapeutic effects on the sedecamycin as a feed supplement for pig. As a results of the study, the following conclusion were obtained: 1. The daily weight gain and feed conversion ratio of sedecamycin administration group was statisticaly significant excellent than that of the control group in pigs(p<0.01, p<0.0.5). 2. In the prophylatic effects, sedecamycin administration group was inhibiter occurrence of swine dysentery than control group in piglets. 3. In the threapeutic effects, sedecamycin administration group was statisticaly significant excellent than that of the control group in piglets(p<0.05).

      • KCI등재

        맹출장애를 보이는 상악 전치의 맹출유도

        심정호,음종혁,정태성,김신 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.1

        상악 전치의 맹출장애는 임상적으로 비교적 흔한 치열발육 이상으로 환자측에서 인지하기 쉬우며 심미적, 사회 심리적으로 중요한 문제가 될 수 있다. 맹출장애의 치료방법으로는 주기적 관찰, 공간 확보, 치은 절제술을 포함한 단순 노출 교정적 견인 외과적 노출과 교정적 견인의 병행, 발거 후 자가치아이식 등 여러 방법이 있다. 이 중 적절한 치료방법을 선택하기 위해서는 우선 환자의 내과적, 치과적 병력을 고려해야 하고 치아의 위치, 상태, 치근 형성정도 및 만곡여부, 맹출을 위한 공간 확보 여부, 주위 치조골 및 치주조직의 상태 , 견인 방법 , 이동에 소요되는 기간 등을 고려해야 한다. 저자는 상악 전치부의 맹출장애를 보이는 두 증례를 치험한 바, 첫 번째 증례는 상악 우측 중절치의 이소맹출과 우측 견치의 맹출지연을 주소로 내원한 환자로서, 견치를 노출시킨 후 견인을 시행하였으며 현재 우측 중절치를 배열중이다. 두 번째 증례는 상악 좌측 중절치의 맹출지연을 주소로 내원한 환자로서, 상악 좌측 중절치를 발거한 후 자가치아이식을 시행하였다. 위 증례를 통해서 치아의 맹출력을 기대할 수 없거나 맹출방향이 비정상적인 경우에는 외과적 노출과 견인을 동반한 방법을 우선 적용할 수 있으나, 치아의 위치 이상이 심각하거나 치근의 위치가 과도하게 이탈된 경우에는 자가치아이식을 포함한 외과적 술식이 맹출유도에 도움이 된다는 사실을 확인하였다. Unerupted maxillary anterior teeth is not a common case, However it may present practitioners with management problem. The cause of impaction is considered to be multifactorial, and local cause is the most common. These impacted teeth require surgical intervention, removal, transplantation, or surgical exposure, with or without orthodontic traction to align the malpositioned tooth. The preferred option is surgical exposure and or thodontic correction. Surgical intervention and orthodontic correction should not be delayed to avoid unnecessary difficulties in aligning the tooth in the arch. Surgical exposure should be performed with the intent of providing sufficient attached gingiva rather than simply uncovering the crown, which results in only alveolar mucosal attachment. Attached gingiva is essential to secure the gingival tissues to the adjacent teeth at the dentogingival junction. Thus preventing loss of periodontal tissues as a result of the pull of the surrounding soft tissues and facial museles. Labially impacted maxillary anterior teeth uncovered with an apically positioned flap technique have more unesthetic sequelae than those uncovered with a closed-eruption technique. In the case of severly displaced impacted teeth, autotransplantation ensures preservation of the alveolar bone and will facilitate future placement of an osseointegrated implant once growth has ceased or if ankylosis/resorption of the transplant occurs.

      • 대학생의 비만실태와 식생활 양상에 관한 연구

        이정윤,송태희 서울보건대학 1997 서울보건대학 부설 한국보건과학연구소 논문집 Vol.4 No.1

        The purpose of this survey was to investigate the prevalence of obesity, eating behaviour and life style of college students. This survey was carried out anthropometry and questionnaires in 236 male and 248 female college students in Seoul and Kyongi area. The results are summerized as follows : 1) Average skinfold thickness of the triceps and subscapular in female students were higher than those of male students. Average percentage of body fat in female was higher than that of male. The average BMI, WLI, OR of male were 21.8, 100.6, -1.7, respectively and those of female were 20.4, 99.3, -5.7,respectively. Distribution of BMI, WLI, OR and %BF indicated that BMI was more sensitive for identifying underweight whereas %BF was more sensitive for identifying overweight of female. 2) By BMI, 37% of students belong to underweight groups shereas 7% overweight and obesity ones. The female students showed lower obesity indice than the male. Self-evaluated obesity seemed likely to overestimate their body shapes above BMI, which lead to high unsatisfaction toward their body shape. Males want to gain weight slightly and females want to lose 4.9kg weight. All females want to lose weights. Obese male and females want to lose 12kg, 16kg weights, respectively. 3) Obese group had rapid eating rate, overeating habit, preferences of greasy food and instant food more than any other groups. The preferences of fast food, high caloric density food were lower in obese group than in

      • 환경소음의 등고선 표현방법

        金貞泰 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

        A software for predicting apartment noise level is introduced. The program is based on the ray tracing technique which is widely used in the environmental noise analysis and prediction. Especially suited for prediction of environmental noise in apartment complexes, the program features an advanced graphics routine by incorporating bilinear interpolation. As an application, the railway noise distribution in an apartment environment is analyzed. A 3D graphics routine is also developed for illustrating the noise level.

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