한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

선천성 후비공 폐쇄증 : 7예의 분석

김창훈,이정권,최윤석,유신영,윤주헌 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.3

정전기력 구동 마이크로 액츄에이터를 이용한 Si 소재 탄성특성의 온도의존성 평가

鄭聖勳,李世昊,鄭增鉉,權東一 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.8

Electrostatically actuated testing devices were used to estimate the elastic modulus of single-crystalline Si for microeletromechanical systems. The devices were moved laterally by alternating electrostatic force at a series of frequencies, and then a resonance frequency was determined, with temperature cycling, by detecting the maximum displacement. The elastic modulus was calculated from the detected resonance frequency by Rayleigh's energy method. The elastic modulus decreased with heating and then increased with cooling, but after thermal cycle the specimen showed a permanent change to a value lower than the initial one. This phenomenon can be explained, to some extent, by the temperature-dependent variation in interatomic force of Si atoms, but the permanent change in elastic modulus implies that it may also be caused by the formation of a thermal oxide layer on the Si with increasing temperature. Composite bending theory was invoked to analyze the oxide effect and the thickness of the oxide layer formed during thermal cycling was estimated from the permanent change in the resonance frequency. The existence of the oxide layer was confirmed by field emission scanning electron microscopy. Finally, the method for compensating the decreasing elastic modulus with increasing temperature were proposed by using the temperature coefficient of elastic modulus.

10% Sodium Lauryl Sulfate에 의한 피부자극 반응에 대한 연구

이증훈 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

To assess the regional or individual variations of inflammatory response to an irritant, closed patch test with 10% sodium lauryl sulfate was done in nine volunteers. The test was performed at eight sites on the ventral sides of the forearms and on the upper backs of each volunteers. The degree of inflammation was greater on the upper backs than on the forearms. The degree of variations among test sites and subjects was greater on the forearms than on the upper backs.

월남전 당시 살포된 고엽제에 의해 발생한 것으로 생각되는 피부 질환

이증훈,김윤동,서기범,박장규 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Although many dermatologists need adequate information about Agent Orange-related skin lesions, there have been few researches about them. We observed various skin manisfestations from 266 Korean Vietnam veterans who visited Department of Dermatology, Chungnam National University Hospital, inculding seborrheic dermatitis(46%), xerotic eczema(45%), chloracne(30%), generalized pruritus (10%), dermographism (5%), chronic urticaria (4%), photosensitive dermatitis (3%), etc. Among them chloracne is well known as a disease which results from exposure to Agent Orange which was used for a defoliating agent during Vietnam war. It is a refractory acneiform eruption due to halogenated polyaromatic compounds(eg. dioxin, dibenzofurane, polychlorinated biphenyls, etc.). 2,3,7,8-tetrachlorodibenzo-p-dioxin, a kind of dioxin isomer, contained in the Agent Orange which was used for a defoliating agent during Vietnam war. It is characterized by recalcitrant comedones and cysts predominantly in the malar and postauricular area. We concluded that the various skin lesions in Vietnam veterans resulted from probably the chemicals in defoliant and further researches would be required to find out subjective guidelines for the evaluation of the skin lesions.

완선에 대한 항진균제(clotrimazole) 단독 및 스테로이드가 첨가된 복합체(Triamcinolone acetonide and Hydrocortisone)의 치료효과에 관한 비교 연구

이증훈,서우영,김기홍,최종수 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

Although the combination products of antifungal agents and corticosteroids are often used in the treatment of superficial fungal infections, their usefulness is not settled. The combined corticosteroids may promote the spread of fungi. On the other hand, they can bring rapid relief from signs and symptoms and increase the local concentrations of the antifungal agents in the skin due to the vasoconstrictive effect. This study was performed to compare an antifungal agent with its combination products with corticosteroids in the treatment of tinea cruris. Seventy-four patients with tinea cruris, aged 18-26 years, were admitted to the study. All ere soldiers living in the same conditions. Sixty patients completed 2 weeks of therapy : clotrimazole, 19 ; combination with trimacinolone acetonide, 28; combination with hydrocortisone, 13. All treatments almost completely improved the lesions at the end of 2-week period. No specific treatment was significantly better. After 4 weeks the relapse rate was highest in the group treated with clotrimazole combined with triamcinolone acetonide (75%), compared with clotrimazone alone (47%) or its combination with hydrocortisone (50%), but not significant statistically (p<0.05).

반도체 습식세정에서 오존이 첨가된 초순수수에 대한 연구

한정훈,박진구 漢陽大學校 工學技術硏究所 1997 工學技術論文集 Vol.6 No.1

The purpose of this study is to investigate the behavior of ozone in DI water that has been applied to replace H2O2 in semiconductor wet cleaning processes. The concentration of ozone as a gas phase was measured by both a titration and the electrolysis method. The titration method was more accurate than the electrolysis method. However, the concentration of ozone in DI water showed better accuracy in measurements using electrolysis method. The concentration of the generated ozone gas was a function of the applied power and the oxygen flow rate. The solubility of ozone in DI water was dependent on the input gas flow rate and concentration. To reach a saturation of ozone concentration in DI water, it took around 15 min. The solubility of ozone in DI water was a strong function of the input ozone concentration.

아연 전처치가 카드뮴 급성 중독에 미치는 영향에 대한 실험적 연구

이정훈,최정목,강대영 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

In an attempt to elucidate the effects of zinc on rat tissue changes induced by cadmium, the present study was undertaken in male Sprague-Dawley rats. Rats were intraperitoneally pretreated with zinc chloride(15.0mg/kg) for 3 days, and then were intraperitoneally given CdCl_2(3.0mg/kg). The body and organ weights of the experimental rats were weighed on the 1st, 3rd, 7th, 15th, 30th and 60th day after CdC_12 injection. The lungs, livers, kidneys and testes were microscopically illuminated and examined under the electron microscope. The results were as follows: 1. The cadmium induced toxicity were most prominent in the testes. The testes showed diffuse hemorrhage, followed by massive hemorrhagic necrosis, calcification and complete disappearance of normal parenchymal tissue(severe atrophy). 2. In the zinc treated group, there were no specific light microscopic changes in the organs. Marked ultrastructural changes were not observed, however the number of glycogen particles increased. 3. The cadmium toxicity to the lung was proportional to the number of days. The lung changes showed chronic bronchitis and progressive interstitial fibrosis of the alveoli. 4. In the cadmium treated group, the liver showed ultrastructural changes such as mitochondrial swelling, dilatation of rough endoplasmic reticulum, myelin figure formation, and decreased number of glycogen particles. The degree of ultrastructural changes slightly decreased in the zinc pretreated group. Also nuclear membrane irregularity was noted after experimental 30th day. 5. After 30th experimental day in the cadmium treated group, ultrastructural appearence of the proximal convoluted tubules of the kidneys showed detachment of microvilli, absence of basal cytoplasmic membrane invagination and irregular mitochondrial shape. In the zinc pretreated group, the degree of ultrastructural changes were mild compared to those of the cadmium only treated group. In conclusion, these experimental results suggest that cadmium toxicity was most prominent in the testes and can be the cause of infertility, and that zinc reduces ultrastructural cellular damage induced by cadmium in the rat tissues.

간접면역형광법을 이용한 쭈쭈가무시병의 혈청학적 진단

이증훈,성열훈 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

To determine the antibody titer for the diagnosis of tsutsugamushi disease by indirect immunof-luorescent test n Korea, the antibody titers of 6572 sera of the residents and 296 sera of the 109 patients confirmed as tsutsugamushi disease in the Cungcheung area were analyzed. At cut-off point of 1:40 specificity was 98% and sensitivity, positive predictive value and negative predictive value were 49%, 90%, 86% during the first week after onset, 85%, 94%, 95% during the second week, and 96%, 95%, 99% during the third week. At cut-off point of 1:80 specificity was 99% and sensitivity, positive predictive value and negative predictive value were 47%, 94%, 86% during the first week, 85%, 97%, 95% during the second week, and 96%, 97%, 99% during the third week. At cut-off point of 1:160 specificity was 100% and sensitivity, positive predictive value and negative predictive value were 31%, 995, 82% during the first week, 69%, 100%, 91% during the second week, and 89%, 100%, 97% during the third week.

쓰레기 종량제 개선에 대한 평가 연구

정경훈,최형일,김정애,박상일 조선대학교 환경공해연구소 2007 環境公害硏究 Vol.20 No.1

It is ten years since the volume based waste free system carried out. This aimed to analysis and estimate about the achievement of the volume based waste free system of the Ministry of Environment and Damyang-Gun. According to the analysis of its result, it is still unsatisfied to use the plastic bags of the volume based waste free system and to separate and throw away the wastes. The Public Opinion says that the Government needs to further step up publicity activities on the volume based waste free system by making good use of TV, newspaper, and magazine, and should offer the incentives to people who observe the volume based waste free system, In addition, it says that people in Damyang-Gun incinerate illegally(60.5%). Therefore. the study and supply of waste disposal method is necessary to people in Damyang-Gun, manufacturers themselves should collect wastes, and Damyang-Gun should expend the systematical device of collecting wastes. If these things go on, the volume based waste free system will be fixed.