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Jeon, Ju‐,Hyun,Yang, Ji‐,Yeon,Lee, Hoi‐,Seon John Wiley Sons, Ltd 2014 Pest Management Science Vol.70 No.7
<P><B>Abstract</B></P><P><B>BACKGROUND</B></P><P><B>The acaricidal activities of (±)‐camphor structural analogues against house dust mites were evaluated using the impregnated fabric disc bioassay.</B></P><P><B>RESULTS</B></P><P><B>The acaricidal effects of camphor and its structural analogues were evaluated against <I>Dermatophagoides farinae</I> and <I>D. pteronyssinus</I>. Based on the LD<SUB>50</SUB> values against <I>D. farinae</I>, (±)‐camphor (0.95 µg cm<SUP>−2</SUP>) was 38.75 times more effective than <I>N</I>,<I>N</I>‐diethyl‐<I>m</I>‐toluamide (DEET) (36.81 µg cm<SUP>−2</SUP>), followed by (+)‐camphor (1.41 µg cm<SUP>−2</SUP>), (−)‐camphor (2.03 µg cm<SUP>−2</SUP>) and (1R)‐camphor oxime (3.31 µg cm<SUP>−2</SUP>) in the impregnated fabric disc bioassay. However, camphor‐10‐sulfonic acid and camphoric acid had no observable activity against <I>D. farinae</I> or <I>D. pteronyssinus</I>. The acaricidal activities of camphor and its structural analogues against <I>D. pteronyssinus</I> were similar to those against <I>D. farinae</I>.</B></P><P><B>CONCLUSION</B></P><P><B>These results indicate that camphor and its structural analogues are suitable for producing acaricidal agents against house dust mites. © 2014 Society of Chemical Industry</B></P>