완전 방실차단을 동반한 급성 심근염

이유선,정진옥,박용규,박형서,노상필,정승현,김정희,이재환,최시완,성인환 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

급성 심근염환자에서 발행한 완전 방실차단을 영구 심장박동 조율기로 치료한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Myocarditis, an inflammatory process involving the myocardal wall, may be caused by most infectious agents. Irrespective of its etiology, it presents commonly with evidence of heart failure, hypotension, and various electrocardiographic abnormalities. Patient with myocarditis may be asymptomatic or may have a rapidly progressive fatal disease. Medical management of patients with myocarditis includes specific therapy for underlying infection and control of the complication of myocarditis such as congestive heart failure and arrhythmia. Recently we had experienced myocarditis with complete atrioventricular block in 37-year-old man. Although he had shown complete recovery of heart failure, he had shown complete atrioventricular block, so we inserted permanent pacemaker. We report it with review of the literature.

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.

전기충격요법 사용에 관한 정신과의사의 견해 및 실시현황

정환증,변원탄 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.4

한국 정신과 의사 211명의 전기충격요법에 관한 의견을 다음과 같이 요약할 수 있었다. 1. 735가 치료방법으로서의 전기충격요법을 찬성하는 태도였고, 찬성하는 가장 큰 이유로서는 적응증만 잘 고려된다면 일반적으로 우수한 효과를 볼 수 있다는 것이었다. 그러나, 그 실제적인 사용에 있어서는 다수에서 조심스러운 태도를 보이고 있었고, 어떤 견해에 있어서는 미국의 정신과 의사들보다 훨씬 더 소극적인 태도를 가지고 있었다. 2. 전기충격요법의 적응증에 관한 한 역시 예상한 바와 같이 주요 우울장애, 조증 흥분, 정신분열증의 순으로 찬성하는 경향이 많았고, 이 방법을 선택한 이유로는 '응급처치로 시행하거나' 다른 치료방법에 실패했거나' '보다나은 결과를 얻기 위한 병용 치료로서 선택' 등이 가장 많았다. 3. 정신분열증에서의 전기충격요법은 사용의 한계를 나타내고 있었다. 4. 시행 이전의 동의나 시행 전 감사에 대해서는 비교적 엄격한 태도를 유지하고 있으나, 연성 전기충격요법, 편측 전기충격요법의 활용은 적었으며, 강력 또는 유지 전기충격요법 역시 시행율이 낮은 편이였다. 시행빈도는 79%가 주2-3회를 실시하는 것으로 나타났고, 향정신약물을 사용하던 환자에서 전기충격요법을 시행한 경우, 대체로 약간의 약물 감량을 실시하는 것으로 나타났다(59%) 5. 전기충격요법 시행 이후의 합병증으로는 골절이나 탈구, 직업 수행 능력에 영구적인 장애, 자발적인 경련 발작 등이 예상외로 많아 합병증은 역시 소홀히 할 수 없는 문제임을 나타내 보였으며, 전기충격요법 이후 24시간이내 사망을 경험한 예가 6경우가 있었다. The authors of this suveyed the opinions of 211 Korean psychiatrists about the use of Electoconvulsive Theraoy(ECT). The results of the survey are summarized as follows; 1. ECT was accepted with a favorable attitude by 73% of the psychiatrists surveyed. The most common reason for agreement was that if indication is followed the ECT generally produces excellent results. But in actual clinical practice most Korean psychiatrists are hesitant in preforming the ECT and have a somewhat less active attitude towards ECT than psychia trists in America. 2. The major indications for theuse of ECT were major depression, manic excithment and schizophrenia in the order of their frequency. The main reasons for the selection of ECT as a therapeutic tool were emergency therapy, when all other treatment methods have failed and as a combined treatment that can. 3. The use of the ECT for the treatment of schizophrenia was very limited for a few selected cases. 4. Korean psychiatrists showed relatively rigid adherence to obtaining the consent before ECT and the preoperational work-up. The softening and unilateral ECT had received little use in Korea and a similar tendency was shown towards intensive and maintenance ECT. Most psychiatrists(79%) tended to use the ECT 2 or 3 times a ewek with a majority of their patients. In cases where the ECT was used in concomitant with antipsychotic drug therapy, there showed a tendency for a slight reduction in drug dosages during the ECT. 5. Post-ECT complications and/or adverse effects were fracture, dislocation, premanent disability in occupational performane and spontaneous seizures etc. Occurrences of above complications seem to be mlre than expected in this study and this was not negligible. A total of six patients were known to habe expired within twenty-four hours after ECT.

국가대표 남자 체조선수들의 실수 원인에 대한 질적 연구

정진근,김정완 한국스포츠심리학회 2003 한국스포츠심리학회지 Vol.14 No.1

본 연구의 목적은 국가대표 남자 체조선수들이 인식하고 있는 실수 원인을 면담을 통해 심층적으로 분석하여 실수 원인에 대한 정보를 제공함으로써 우수한 경기력 발휘에 어려움을 겪고 있는 일반선수들이나 현장에서 선수를 지도하는 지도자들에게 실수에 대한 대처방안을 강구할 수 있도록 하기 위함이다. 본 연구에서는 제14회 아시안 게임에 참가한 국가대표 남자 체조선수들을 대상으로 실수 원인을 밝혀내기 위하여 심층면담을 하였으며 면담을 통해 얻어진 자료를 귀납적 방법으로 내용 분석을 하였다. 내용 분석 한 결과는 다음과 같다. 실수의 원인은 신체적 요인, 심리적 요인, 인적 요인, 환경적 요인으로 모두 4가지 범주로 분류되었다. 신체적 요인의 범주 안에는 1가지의 원자료가 분류되었으며, 심리적 요인의 범주 안에는 가장 많은 8가지의 원자료가 분류되었다. 그리고 인적 요인에 3가지의 원자료가 분류되었고 환경적 요인에 1가지의 원자료가 분류되었다. 이러한 결과를 바탕으로 경기중 실수를 줄이기 위해서는 심리적 실수 유발 요인을 통제하는 것이 중요하며 따라서 실수의 심리적 원인에 적절히 대처할 수 있는 훈련과 연습이 필요하다는 제안을 하였다. The purposes of this study are to analyze the reasons of mistakes that male gymnastic players recognize through the interviewing and to plan to deal with those problems by presentation the informations about the reasons of mistakes to the general gymnastic players and the directors. This study makes the targets for the analysis the male gymnastic players that participated in the 14th Asian Games as the members of the national team. The materials that was drawn through the depth interviewing are analyzed inductively. The results of this study are as follows : The reasons of mistakes are classified into four categories : the physical factor, the psychological factor, the human relations factor, and the environment factor. There is a raw date in the physical factor, and 8raw date in the psychological factor. Then, there are 3raw date in the human relations factor, and a raw date in the environment factor. With these results in mind, the following recommendations may be possible. First, it is important that the psychological reasons are controlled to reduce the mistakes in the match. Second, it is necessary that the gymnastic players must practice and be trained to prepare the psychological reasons of the mistakes.

멕시코와 네팔에서 도입한 고추 유전자원의 풋마름병 및 역병 저항성

고보환,김정훈,전수경,이지선,김병수 慶北大學校 農業科學技術硏究所 2005 慶北大農學誌 Vol.23 No.-

Above 130 accessions of pepper consisting of 50 introductions from Mexico and Nepal, and resistant and susceptible controls were tested for resistance to bacterial wilt and to Phytophthora root rot at seedling stage by artificial inoculation. As the results, KC897, KC939, KC936 were newly found resistant to bacterial wilt in addition to already known resistance sources such as KC126, KC350, KC351, KC353. No new sources of resistance to Phytophthora root rot were found among the introductions from Mexico and Nepal.

環境 行政訴訟(I)

曺正煥 단국대학교 대학원 1988 學術論叢 Vol.12 No.-

Nowaday the environmental pollution, which is driving us, into the crisis of ruin, has been a serious problem day after day. The phenomenon is massive and collective trepass that resulted from the rapid change of the structure of industry and consumption, which civil law could not even imagine at the start of its formation. As the aspect of environmental pollution presently has a tendency to be expanded quantitatively, generalized regionally and complicated contently and intensified in the damage and damaged continually and cumulatively and positional nonsubstitution between sufferer and offender. It is difficult to remedy efficiently the environmental pollution with only the means of civil law remedy. It goos without saying that Administrative agency has the primary responsibility for the proper management of environment. In case Administrative agency, however, encrouches on peoples environmental right by exercising its public power or not exercising it illegally, Legal Remody in response to those cases must be secured. When a citizen opens an Environmental administrative litigation against the govrnment because he has been injured by the environmental pollution, he must be asked if he has the qualification of standing to sue. As the existence of legal interest is essential for the proof of standing to sue in general hearings of administrative litigation, legal interest as a criterion of acknowledging standing to sue is required to determin the magnitude of environmental interest in environmental administrative litigation. Concurring efforts between the goverement and citizens are indispensable for the environmental preservation. The court of justice must establish new patterns of judicial review considering the characteristic of environmental litigation which requires a highly professional, technical, and scientific judgment. It's quite encouraging that we have established articles environmental right in our new constitution. Hence, we must make supreme efforts in order that the people environmental right, which section 35 of the constitution of the republic of Korea assures, might be secured fully, not only by simple provision itself, but also be administrative litigation.

Prostacyclin synthase 유전자의 C1117A 다형성과 이형협심증과의 관련성

성인환,임대승,김정희,이재환,최시완,정진옥 대한내과학회 2004 대한내과학회지 Vol.66 No.4

목적 : Thromboxan A2의 혀관수축반응을 저해하는 prostacylin synthase exon 8 C117A의 변이가 관동맥 연축과 관련성이 있는지를 알아보고자 하였다. 방법 : 1998년 1월 1일부터 2000년 12월 31일까지 충남대학교병원 순환기내과에서 관동맥조형술과정맥내 에르고노빈 유발검사를 시행하여 관동맥 연축이 확진된 이형협심증 환자군(45예)과 정상 대조군(59예)을 대상으로 중합효소 연쇄반응법 및 restriction fragment length polymorphism을 이용하여 분석하였다. 결과 : Prostacyclin synthase exon 8 C117A 유전자형의 빈도는 대조군에서 A/A : A/C : C/C =3.4% : 30.5% : 66.1%, 이형협심증 환자군에서 A/A : A/C : C/C = 8.9% : 42.4% : 48.9%로 두 군간에 유의한 차이가 없었다. 대조군에 비해 변이형 협심증 환자군에서 남자의 비율과 흡연률이 높았지만, prostacyclin synthase exon 8 C117A 유전자형에 따른 군에서 당뇨병, 고혈압, 흡연, 고지혈증, 비만 등의 유의한 차이는 없었다. 결론 : 한국인에서 prostacyclin synthase exon 8 C117A 유전자 다형성과 관동맥 연축이 있는 이형협심증과의 유의한 연관성은 발견할 수 없었다. Backround : Coronary artery spasm plays an important role in the pathogenesis of variant angina(VA). Prostacyclin is one of the endothelium derived relaxing factors. The association between the novel single nucleotide polymorphism in the prostacyclin synthase gene and VA is not known. Therefore, we investigated the association between VA and the polymorphysm in the prostacyclin synthase gene. Methods : We compared 45 variant angina patients who had positive intravenous ergonovine test by coronary angiography with 59 control subjects who had negative intravenouis ergonovine test and normal coronary angiogram. Using the polymerase chain reaction-single-strand conformation polymorphism analysis, we identified a single nucleotide polymorphism, C117A, in exon 8. This nucleotide change did not cause an amino acid change in codon 373. Results : There was no significant difference in characteristics between the control group and the VA group, and there was no significant difference in the genotype distributions between the control group and the VA group. Conclusion : The C117A polymorphism in exon 8 of the prostacyclin synthase gene is not associated with variant angina.

'지역농업'재편과 지자체의 역할에 관한 연구

유정규,장우환 한국농업정책학회, 한국축산경영학회 2003 농업경영정책연구 Vol.30 No.3

This study focuses upon the following three points. Firstly, it presents the necessities, objectives, and policy directions of restructuring the regional agriculture. Secondly, the local government is emphasized as the subject which will lead the restructuring process. Lastly, it tries to find possibilities and limitations of the restructuring of regional agriculture, in particular through the case study about a local region, Maneui-myun, Chongwon-gun, Chungchungbuk-do. The study provides valuable implications about what are the desirable roles to be played by the local government as the leading subject for regional agricultural development.

고등학교 역도선수의 체중감량이 체력에 미치는 영향

신정섭,김세환 江原大學校附設體育科學硏究所 1997 江原大學校附設體育科學硏究所論文集 Vol.- No.21

This study was taken their weight and measured eight and measured kinds of physical fitness for the study intended for fourteen weight lifters in Kangwon Physical High School. The measure had been carried for ten days before the game. We have also measured the physical fitness while reducing their weight for two days. We compared the result after the loss in weight with that of before. As a result, we have the conclusion as follow 1. According to the statistics, there was no significant difference in muscular fitness (sit- up, back muscular strength, vertical arm pull test) between the two results. 2. There was no significant difference in leg muscula power (sarjent jump) statistically. 3. There was no significant difference in muscula endurance (handstand push-up, pull squat). 4. Statistically, we had no significant difference in agility (side-step) 5. The appropriate weight for lifters is about two kilograms lower than usual. Two kilograms mean about three percent of his own weight. As mentioned above, we can see that the method, the degree and the period of the loss in weight don't influence the physical strength for weight lifters. Therefore, they need to keep their weight proper all the time within the limit of around two kilo-grams of weight limits.