http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Probability Density Function for the Critical Current Asymmetry of a HTS dc SQUID
Jen-Tzong Jeng,C. H. Wu,H. C. Yang,H. E. Horng,J. C. Chen,K. H. Huang,K. L. Chen,S. H. Liao,Y. C. Lin 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.48 No.5I
A dc SQUID consisting of grain boundary Josephson junctions may often be asymmetric owing to the large critical-current spread. In this work, the probability density function (PDF) for the critical-current asymmetry of high-transition-temperature-superconductor (HTS) dc SQUID was investigated. To model the critical-current spread in the grain boundaries, we assumed that the barrier thickness of the Josephson junction fluctuated according to a log-Weibull distribution. The resultant PDF for the critical-current spread that fits the histogram data of critical currents reported in literature was the gamma distribution. With the proposed distribution function, the corresponding PDF for the critical-current asymmetry parameter of a HTS dc SQUID was derived and compared with the experimental result. The proposed gamma distribution function is useful in modeling devices, such as the SQUID array and the superconducting quantum interference grating, consisting of many grain-boundary Josephson junctions.
Hybrid Observer Concept for Sensor Fusion of Sporadic Measurements for Underwater Navigation
Jens E. Bremnes,Astrid H. Brodtkorb,Asgeir J. Sørensen 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.1
Accurate underwater navigation systems are required for closed-loop guidance and control of unmannedunderwater vehicles (UUV). This paper proposes a sensor-based hybrid translational observer concept for underwater navigation using the hybrid dynamical systems framework, accounting for noisy, asynchronous and sporadicsensor measurements. Sensor measurements from an acoustic positioning system, a Doppler Velocity Log (DVL),an Inertial Measurement Unit (IMU) and a pressure gauge are used in the proposed observer. A method for filteringhigh-frequency noise is proposed, where the estimated states are obtained by taking a weighted discounted averageof a finite number of previous measurements predicted forwards to the current time. The attitude of the vehicle isassumed known, and the acceleration measurements are assumed to be continuously available. Measurements ofposition, depth and linear velocity are assumed to be asynchronous and sporadically available, that is, they do notarrive at the same time, and their sampling rates are not constant. Uniform global asymptotic stability (UGAS) is established using Lyapunov theory for hybrid systems. Results from simulations are presented in order to demonstratethe performance of the proposed method.
Jeng, Jen-Eing,Wu, Hui-Fang,Tsai, Meng-Feng,Tsai, Huey-Ru,Chuang, Lea-Yea,Lin, Zu-Yau,Hsieh, Min-Yuh,Chen, Shinn-Chern,Chuang, Wan-Lung,Wang, Liang-Yen,Yu, Ming-Lung,Dai, Chia-Yen,Tsai, Jung-Fa Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
To assess the contribution of tumor necrosis factor $(TNF){\beta}$ +252 polymorphisms to risk and prognosis of hepatocellular carcinoma (HCC), we enrolled 150 pairs of sex- and age-matched patients with HCC, patients with cirrhosis alone, and unrelated healthy controls. $TNF{\beta}$ +252 genotypes were determined by polymerase chain reaction with restriction fragment length polymorphism. Multivariate analysis indicated that $TNF{\beta}$ G/G genotype [odds ratio (OR), 3.64; 95%CI, 1.49-8.91], hepatitis B surface antigen (OR, 16.38; 95%CI, 8.30-32.33), and antibodies to hepatitis C virus (HCV) (OR, 39.11; 95%CI, 14.83-103.14) were independent risk factors for HCC. There was an additive interaction between $TNF{\beta}$ G/G genotype and chronic hepatitis B virus (HBV)/HCV infection (synergy index=1.15). Multivariate analysis indicated that factors associated with $TNF{\beta}$ G/G genotype included cirrhosis with Child-Pugh C (OR, 4.06; 95%CI, 1.34-12.29), thrombocytopenia (OR, 6.55; 95%CI, 1.46-29.43), and higher serum ${\alpha}$-fetoprotein concentration (OR, 2.53; 95%CI, 1.14-5.62). Patients with $TNF{\beta}$ G/G genotype had poor cumulative survival (p=0.005). Cox proportional hazard model indicated that $TNF{\beta}$ G/G genotype was a biomarker for poor HCC survival (hazard ratio, 1.70; 95%CI, 1.07-2.69). In conclusion, there are independent and additive effects between $TNF{\beta}$ G/G genotype and chronic HBV/HCV infection on risk for HCC. It is a biomarker for poor HCC survival. Carriage of this genotype correlates with disease severity and advanced hepatic fibrosis, which may contribute to a higher risk and poor survival of HCC. Chronic HBV/HCV infected subjects with this genotype should receive more intensive surveillance for early detection of HCC.
Anne E Olesen,Debbie Grønlund,Esben B Mark,Klaus Krogh,Jens B Frøkjær,Asbjørn M Drewes 대한소화기 기능성질환∙운동학회 2019 Journal of Neurogastroenterology and Motility (JNM Vol.25 No.4
Background/Aims Opioids cause gastrointestinal (GI) dysmotility, decrease gut secretion, and affect gut sphincters. Symptoms of opioid-induced bowel dysfunction may be alleviated by peripherally acting opioid antagonists like naloxegol, but detailed knowledge on GI effects of this drug is lacking. We hypothesized that naloxegol, compared to placebo, would reduce GI transit time and colonic fecal volume in opioid-treated healthy participants. Methods We conducted a randomized, double-blinded, single-center, 2-way cross-over study in 24 healthy males, randomized to a 6 day treatment period of oxycodone (15 mg twice a day) co-administered with either naloxegol (25 mg once a day) or matching placebo. Participants swallowed an electromagnetic capsule which determined GI transit times. Colonic fecal volume was quantified with magnetic resonance imaging both pre-treatment and post-treatment. Results Naloxegol reduced total GI transit time by 21% (56 hours vs 71 hours, P = 0.02) and colonic transit time by 23% (45 hours vs 59 hours, P < 0.01), compared to placebo. However, no difference in colonic fecal volume was found (818 mL vs 884 mL, P = 0.20). Conclusions Short-term administration of naloxegol in healthy participants reverses the retardation of total GI and colonic transit induced by oxycodone. This supports the use of naloxegol in the treatment of GI side effects to opioid treatment, and add knowledge to the current understanding of mechanisms behind peripherally-acting opioid antagonists.
Jeng, Jen-Eing,Tsai, Meng-Feng,Tsai, Hey-Ru,Chuang, Lea-Yea,Lin, Zu-Yau,Hsieh, Min-Yuh,Chen, Shinn-Chern,Chuang, Wan-Lung,Wang, Liang-Yen,Yu, Ming-Lung,Dai, Chia-Yen,Tsai, Jung-Fa Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
The pathogenesis of hepatocellular carcinoma (HCC) related to habitual betel quid (BQ) chewing is unclear. Risk of HCCis increased with adverse hepatic fibrosis. This study aimed to assess the impact of chronic viral hepatitis on adverse hepatic fibrosis in HCC related to BQ chewing. This hospital-based case-control study enrolled 200 pairs of age- and gender-matched patients with HCC and unrelated healthy controls. Serologic hepatitis B surface antigen (HBsAg), antibodies to hepatitis C virus (anti-HCV), ${\alpha}$-fetoprotein (AFP), and surrogate markers for significant hepatic fibrosis were measured. Information on substance-use habits was obtained with a questionnaire. By analysis of surrogate markers for hepatic fibrosis, the prevalence of significant hepatic fibrosis in patients chewing BQ was between 45.8% and 91.7%, whereas that for patients without BQ chewing was between 18.4% and 57.9%. The difference was significant (P <0.05 for each surrogate marker). Multivariate analysis indicated that cirrhosis with Child-Pugh C (odds ratio (OR) = 3.28; 95% confidence interval (CI), 1.29-8.37), thrombocytopenia (OR = 3.92, 95% CI, 1.77-8.68), AFP >400 mg/L (OR = 2.21, 95% CI, 1.05-4.66) and male gender (OR = 4.06, 95% CI, 1.29-12.77) were independent factors associated with habitual BQ chewing. In conclusion, adverse hepatic fibrosis and severe liver damage play important roles in the pathogenesis of BQ-related HCC, which could be aggravated by chronic hepatitis B and hepatitis C. BQ-cessation programs and prevention of chronic HBV/HCV infection are needed to prevent HCC related to BQ chewing.
Acoustic Monitoring and Localization for Social Care
Stefan Goetze,Jens Schroder,Stephan Gerlach,Danilo Hollosi,Jens-E. Appell,Frank Wallhoff 한국정보과학회 2012 Journal of Computing Science and Engineering Vol.6 No.1
Increase in the number of older people due to demographic changes poses great challenges to the social healthcare systems both in the Western and as well as in the Eastern countries. Support for older people by formal care givers leads to enormous temporal and personal efforts. Therefore, one of the most important goals is to increase the efficiency and effectiveness of today’s care. This can be achieved by the use of assistive technologies. These technologies are able to increase the safety of patients or to reduce the time needed for tasks that do not relate to direct interaction between the care giver and the patient. Motivated by this goal, this contribution focuses on applications of acoustic technologies to support users and care givers in ambient assisted living (AAL) scenarios. Acoustic sensors are small, unobtrusive and can be added to already existing care or living environments easily. The information gathered by the acoustic sensors can be analyzed to calculate the position of the user by localization and the context by detection and classification of acoustic events in the captured acoustic signal. By doing this, possibly dangerous situations like falls, screams or an increased amount of coughs can be detected and appropriate actions can be initialized by an intelligent autonomous system for the acoustic monitoring of older persons. The proposed system is able to reduce the false alarm rate compared to other existing and commercially available approaches that basically rely only on the acoustic level. This is due to the fact that it explicitly distinguishes between the various acoustic events and provides information on the type of emergency that has taken place. Furthermore, the position of the acoustic event can be determined as contextual information by the system that uses only the acoustic signal. By this, the position of the user is known even if she or he does not wear a localization device such as a radio-frequency identification (RFID) tag.
Stability Analysis and Design of Steel Building Frames Using the 2005 AISC Specification
Donald W. White,Andrea E. Surovek,Bulent N. Alemdar,Ching-Jen Chang,Yoon Duck Kim,Garret H. Kuchenbecker 한국강구조학회 2006 International Journal of Steel Structures Vol.6 No.3
The 205 AISC Specification reflects the latest advances in the stability analysis and design of structural steel buildings. Theor devise their own methods within these constraints. It also provides several specific procedures. This paper first gives anoverview of the elastic analysis and design procedures in AISC (205) as wel as specific second-order distributed plasticitymethods upon which, in part, these procedures are based. The relationship between the AISC elastic provisions and the refinedinelastic methods is explained. Secondly, the paper highlights one interpretation of the AISC inelastic analysis and designgfour basic examples selected to ilustrate key characteristics of each of the methods.
Acoustic Monitoring and Localization for Social Care
Goetze, Stefan,Schroder, Jens,Gerlach, Stephan,Hollosi, Danilo,Appell, Jens-E.,Wallhoff, Frank Korean Institute of Information Scientists and Eng 2012 Journal of Computing Science and Engineering Vol.6 No.1
Increase in the number of older people due to demographic changes poses great challenges to the social healthcare systems both in the Western and as well as in the Eastern countries. Support for older people by formal care givers leads to enormous temporal and personal efforts. Therefore, one of the most important goals is to increase the efficiency and effectiveness of today's care. This can be achieved by the use of assistive technologies. These technologies are able to increase the safety of patients or to reduce the time needed for tasks that do not relate to direct interaction between the care giver and the patient. Motivated by this goal, this contribution focuses on applications of acoustic technologies to support users and care givers in ambient assisted living (AAL) scenarios. Acoustic sensors are small, unobtrusive and can be added to already existing care or living environments easily. The information gathered by the acoustic sensors can be analyzed to calculate the position of the user by localization and the context by detection and classification of acoustic events in the captured acoustic signal. By doing this, possibly dangerous situations like falls, screams or an increased amount of coughs can be detected and appropriate actions can be initialized by an intelligent autonomous system for the acoustic monitoring of older persons. The proposed system is able to reduce the false alarm rate compared to other existing and commercially available approaches that basically rely only on the acoustic level. This is due to the fact that it explicitly distinguishes between the various acoustic events and provides information on the type of emergency that has taken place. Furthermore, the position of the acoustic event can be determined as contextual information by the system that uses only the acoustic signal. By this, the position of the user is known even if she or he does not wear a localization device such as a radio-frequency identification (RFID) tag.