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Jayasinghe, J.D.H.E.,Elvitigala, D.A.S.,Whang, I.,Nam, B.H.,Lee, J. Academic Press 2015 Fish & shellfish immunology Vol.45 No.2
Haptoglobin (Hp) and serum amyloid A (SAA) are two vital proteins involved in inflammatory reactions and are classified as acute-phase proteins. They are released from hepatocytes under inflammatory conditions to protect healthy cells from being damaged by pathogens or from self-destructive mechanisms. In this study, a previously constructed black rockfish (Sebastes schlegeli) cDNA library was used to identify the full-length cDNA sequences of Hp and SAA homologs (RfHp and RfSAA, respectively) and characterize them at the molecular level. As expected, in silico analysis of these homologs showed the typical domain architectures of their known counterparts. Open reading frames of RfHp and RfSAA consisted of 942-bp and 313-bp DNA sequences, respectively. The derived polypeptide sequence of RfHp was composed of 313 amino acids (aa) with a predicted molecular weight of 34 kD, whereas RfSAA had a 121-amino acid sequence with a molecular weight of 13 kD. Phylogenetic analysis as well as pairwise sequence alignment results showed that RfHp was more closely related to Oreochromis mossambicus from an evolutionary perspective while RfSAA was closely related to the Epinephelus coioides ortholog. Although both genes were expressed ubiquitously in the tissues analyzed, they were particularly expressed in liver tissue, suggesting their origin in hepatocytes. Quantitative real-time PCR analysis indicated that both RfHp and RfSAA were significantly up-regulated by both bacterial and viral stimulation in liver tissue, affirming their putative importance in the acute phase of first-line host immune defenses.
Exploration of expansion patterns and prediction of urban growth for Colombo City, Sri Lanka
Jayasinghe Pavithra,Raghavan Venkatesh,Yonezawa Go 대한공간정보학회 2021 Spatial Information Research Vol.29 No.4
This study attempts to analyze and simulate urban growth pattern of Colombo city in Sri Lanka which is a dynamic and rapid urbanizing region. The spatiotemporal urban growth patterns during 1997–2019 were first analyzed by comparing Land Cover (LC) maps for time intervals between 1997–2008 and 2008–2019 using intensity and growth pattern analysis. Urban lands in Colombo have grown in a faster rate during 1997–2008 as compared to 2008–2019 period. The prominent spatial expansion pattern during 1997–2008 is outlying, as opposed to edge expansion which is predominant during 2008–2019. These major urban expansion patterns were modeled to predict the future urban structure of Colombo in 2030 using FUTURES (FUTure Urban-Regional Environment Simulation) model. FUTURES is a patch-based, multilevel modeling framework for simulating the emergence of landscape spatial structure in urbanizing regions. Simulated result generated from the model reveals substantial agreement with real ground urban changes showing a kappa value of 0.78. The model allows to predict three different scenarios, namely Business as Usual, Infill Growth and Sprawl showing over 100 km2 increase in urban lands by 2030. Predicted urban structure was then compared with proposed development plan. With certain limitations arising from available data, the model is effective in predicting possible urban scenarios and providing valuable inputs to support better decision making for sustainable development of Colombo city. The results demonstrated in this study would be useful in modelling urban growth in other cities and further validate the efficacy of the proposed workflow.
Jayasinghe Halke Widanelage Udeesh Satheesha KEMA학회 2023 근골격계과학기술학회 Vol.7 No.2
Background Even though the nature of the cricket game is gaining with time, there is a considerable increase in the incidence of injuries ranging from mild to severe. Purpose This study aims to examine the prevalence and anatomical distribution of non-contact musculoskeletal pain among adolescent elite cricket bowlers in Sri Lanka (n=102) over the competition period of the 2019 cricket season. Study design Secondary data collected from Division 1 boys’ schools in Colombo were used for the study. Subjects’ participation was dependent on both parental informed and voluntary consent. Participants were required to answer interviewer-administered questions regarding the presence of non-contact musculoskeletal pain during the competition period of the 2019 cricket season. The data were analyzed using descriptive statistics through the statistical package for the social sciences software. Methods Secondary data collected from Division 1 boys' schools in Colombo were used for the study. Subjects’ participation was dependent on both parental informed and voluntary consent. Participants were required to answer interviewer-administered questions regarding the presence of non-contact musculoskeletal pain during the competition period of the 2019 cricket season. The data were analyzed using descriptive statistics through the statistical package for the social sciences software. Results Among the total sample, 53% of the subjects experienced non-contact musculoskeletal pain. The prevalence of musculoskeletal pain specific to the anatomical site is mostly experienced in the lower back (36.3%), knee (6.9%), and ankle (5.9%) followed by shoulder (2.9%) and groin (1%). 47% of the subjects remained pain-free for the duration of the season. Conclusions Adolescent elite cricket bowlers reported a high prevalence of non-contact musculoskeletal pain. The lower back was the most common anatomical site to occur non-contact musculoskeletal pain. Each person in the multidisciplinary sports medicine team should consider about the conditioning of players to address the nature and the anatomical site of pain.
Cultural Tourism: as A Strategy for Peace Building in Sri Lanka
( Jayasinghe J. D. D. P ) 한국문화관광학회 2022 문화관광연구 Vol.24 No.2
This paper propose the cultural tourism as a strategy for peace building in Sri Lanka examining the cultural festival tourism .Main argument in this article is that the cultural tourism leads to inter cultural understanding, developing mutual relations and building trust among each other. Since the existing peace building approaches are more political, cultural tourism is a strategy could be developed in to practical achievement of the goals of peace building. The methodological approach utilized is qualitative research paradigm, based on grounded theory. Kataragama cultural festival, with its multi ethnic, multi religious characteristics has produced an ideal background for exploration and sustains the above argument.
Jayasinghe J. D. D. P 세계문화관광학회 2009 Conference Proceedings Vol.10 No.0
This paper propose the cultural tourism as a strategy for peace building in Sri Lanka examining the cultural festival tourism. Main argument in this article is that the cultural tourism leads to inter cultural understanding, developing mutual relations and building trust among each other. Since the existing peace building approaches are more political, cultural tourism is a strategy could be developed in to practical achievement of the goals of peace building. The methodological approach utilized is qualitative research paradigm, based on grounded theory. Kataragama cultural festival, with its multi ethnic, multi religious characteristics has produced an ideal background for exploration and sustains the above argument.
Vulnerability of roofing components to wind loads
Jayasinghe, N.C.,Ginger, J.D. Techno-Press 2011 Wind and Structures, An International Journal (WAS Vol.14 No.4
The vulnerability of roofing components of contemporary houses built in cyclonic regions of Australia is assessed for increasing wind speeds. The wind loads and the component strengths are treated as random variables with their probability distributions derived from available data, testing, structural analysis and experience. Design details including types of structural components of houses are obtained from surveying houses and analyzing engineering drawings. Wind load statistics on different areas of the roof are obtained by wind tunnel model studies and compared with Australian/New Zealand Standard, AS/NZS 1170.2. Reliability methods are used for calculating the vulnerability of roofing components independently over the roof. Cladding and batten fixings near the windward gable edge are found to experience larger negative pressures than prescribed in AS/NZS 1170.2, and are most vulnerable to failure.
Vulnerability of roofing components to wind loads
N.C. Jayasinghe,J.D. Ginger 한국풍공학회 2011 Wind and Structures, An International Journal (WAS Vol.14 No.4
The vulnerability of roofing components of contemporary houses built in cyclonic regions of Australia is assessed for increasing wind speeds. The wind loads and the component strengths are treated as random variables with their probability distributions derived from available data, testing, structural analysis and experience. Design details including types of structural components of houses are obtained from surveying houses and analyzing engineering drawings. Wind load statistics on different areas of the roof are obtained by wind tunnel model studies and compared with Australian/New Zealand Standard, AS/NZS 1170.2. Reliability methods are used for calculating the vulnerability of roofing components independently over the roof. Cladding and batten fixings near the windward gable edge are found to experience larger negative pressures than prescribed in AS/NZS 1170.2, and are most vulnerable to failure.
CONTROLLED ELECTRIC FIELD-ASSISTED JETTING FROM VISCOUS AND NANOSUSPENSION MEDIA DROPLETS
S. N. JAYASINGHE 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2006 NANO Vol.1 No.3
This paper reports a study into forming a jet-on-demand to continuous microthreads by subjecting electric fields on high viscosity and low conducting media (concentrated nanosuspensions and dielectric mediums) droplets, placed on a conducting copper plate, which has a similar plate above at a distance of ~ 10 mm. The media used in this investigation has a viscosity ≫ 1000 mPa s and an electrical conductivity ≪ 10-6 Sm-1 and in the case of nanomaterial loading in suspension is 003E; 15 wt.%. The investigation illustrates both the ability to form jets in this configuration and the importance of the volume of media placed as a droplet which has a direct result on the formation of a jet subsequently fragmentating to droplets. At a droplet volume of < Q0, the resting droplet when under the influence of an applied electric field deforms forming a cone, much like those referred to as the "Taylor Cones". On increasing the volume of the droplet to Q0 and applying a voltage of ~ 4.6 kV across the plates, the apex of the cone was observed to pulsate. On further increasing the applied voltage, giving rise to an electric field strength of ~ 0.55 kV/mm, the pulsating apex stabilizes to evolve a stable jet which undergoes instabilities promoting the generation of droplets. Consequently, a fine jet-on-demand is obtained. On increasing the droplet volume to > Q0, forms jets on both plates. The study elucidates the importance of this jetting approach for forming droplet relics containing self-assembled nanoparticles to continuous microthreads from concentrated nanosuspensions and dielectric media for forming structures by deposition that are most useful and have widespread applications in materials science and engineering. Hence, the physical behavior of this droplet deformation — jetting — forming droplets under an imposed field, outlines the discussion presented in this paper.