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      • 동북아 피더네트워크의 Win-win전략에 관한 연구

        장우준(Woo-jun jang),전찬용(Chan-Yong jeon),김태원(Tae-Won Kim),곽규석(Kyu-Seok Kwak),남기찬(Ki-Chan Nam) 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.3 No.1

        최근 중국은 양산항을 개장하여 선사 유치를 위한 다양한 혜택을 제공하고, 일본은 "수퍼중추항만 육성계획“을 세워 항만의 효율성을 바탕으로 비용을 낮추려는 노력을 하고 있다. 또한 선박의 대형화에 의한 중심항만(Hub Port) 위주의 기항과 북중국의 대량 물량 발생지역에 대한 직기항 경향으로 동북아 항만간의 경쟁이 더욱더 치열해 지고 있으며 동북아 역내 피더네트워크 강화의 필요성이 제기되고 있다. 따라서, 본 연구에서는 유럽 피더네트워크 전략 사례를 바탕으로 동북아 피더시장 현황을 파악하고 동북아 피더네트워크 구조를 분석함으로써 동북아 역내 항만 및 선사간의 과당경쟁을 지양하고 서로 Win-Win할 수 있는 터미널의 전략적 활용, 선사간 제휴 확대, 항만간 협력 강화를 위한 구체적인 전략을 제시하였다. Recently, China opened Yangshan port and provides a variety of benefits for shipping companies. Japan plans to reduce logistics costs and improve efficiency through the established "super major ports" project. According to the "hub and spokes" system, the number of direct calls toward North-Chinese ports are increasing. This changing environment has negative effects on the amount of transshipment cargos in Korean ports. In order to make a hub port of a domestic port, it is necessary to develop northeast Asian feeder networks. Therefore, this paper analyzes the structure of northeast Asian feeder networks through the case study of European feeder networks strategy. Finally, we suggests the plans to reinforce feeder networks, which are strategic terminal operation, strategic alliances between shipping companies and port co-operation, for win-win strategy in the competitive northeast Asian market.

      • KCI등재
      • ATM과 멀티미디어를 이용한 원격 교육 시스템

        장원호,박인호,류시국,강현석 慶尙大學校 1996 論文集 Vol.35 No.2

        Recently, student-oriented education paradigms are appeared. At this point, we expect that the future's education will be changed by the distance eduation system based on multimedia materials. This study decribes an integerated real-time multimedia distance eduation system that uses ATM technology, object-relational detabase management system, and multimedia authoring tools to use interactive multimedia materials among remote sites in real-time.

      • 연속식 MMA polymer 중합반응기의 Fuzzy FF/FB제어

        장원혁,강신춘,노시태 한양대학교 공학기술연구소 1992 공학기술논문집 Vol.1 No.1

        A feedforward control law which is efficient in eliminating the effect of measurable disturbances on process outputs is synthesized by a fuzzy modeling. Through analyzing the process operation data sets we constructed the fuzzy model that could calculate the manipulation at steady-state for the load and/or set-point change and designed a feedforward/feedback controller based on it. The designed controller was installed to a CSTR polymerization reactor and its performance was evaluated through simulations.

      • KCI등재후보

        난소 절제 백서에서 17β-Estradiol 투여가 골조직에 미치는 영향

        장원석,김종렬,박봉수,성일용 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.4

        This study was focused on the changes of mineral density and histopathologic features of osseous tissue when ovariectomized rats were administered with 17β-Estradiol. Forty-eight rats, 11 weeks of age, were divided into four groups, which are a normal control group, an ovariectomized control group, an experimental group 1 which was given 17β-estradiol immediately after the ovariectomy and an experimental group 2 which was given 17β-Estradiol 3 weeks after the ovariectomy. They were sacrificed at different time intervals (1, 3, 4 and 8 weeks) for histopathologic observation, histo-morphometric analysis and immunohistochemistry with fibronectin and CD34 antibody. Most rats showed the increase in bone density, which was the least in the ovariectomized control group. In histopathologic features of both the mandible and the tibia, the osteoclasts in bone marrow increased in the ovariectomized control group of more than 3 weeks. In histomorphometric analysis, the osteoclasts increased in both the mandible and the tibia in length of time. In comparison of the increase of osteoclast between four groups, it decreased as following order: the ovariectomized control group, the expermiental group 2 the experimental group 1, the normal control group. Especially the experimental group 1 and experimental group 2 at 4 weeks showed remarkable changes both in the mandible and in the tibia in comparison with the ovariectomized control group. In immunohistochemical anaylsis with fibronectin, the more week-ovariectomized control groups of both the mandible and the tibia showed weaker fibronectin expression in osteoblast and bone marrow. Among the experimental group 1 and 2, 4-week group showed the strongest expression. In immunohistochemical analysis with CD34, the mandible showed generally weak expression but 8-week experimental group 1 and 2 showed relatively moderate expression in osteoblast and bone marrow. In case of the same groups of tibia, 4-week group show the strongest expression. With all these results, it is assumed that 17β-Estradiol has more effect on the development and differentiation of osteoclasts than those of osteoblasts and contributes to the initial bone formation most efficiently by inhibiting osteoclastic action and stimulating osteoblasts.

      • 샌드블라스팅에 의한 도재의 표면처리가 브라켓의 전단결합강도에 미치는 영향

        장원주,김상철 원광대학교 생체재료·매식연구소 1999 원광생체재료·매식 Vol.8 No.1

        The purpose of this study was to evaluate the effect of sandblasting treatment on porcelain, on shear bond strength or bracket. This study was carried out with 192 samples which were divided into 24 groups according to 3 bonding agents and 8 surface treatment methods. Bonding agents were Ortho-oneTM, Transbond XTTM, Fuji Ortho LCTM, and surface treatment methods were differentiated by concentrations of etching agent, and use of silane or sandblasting. After surface treatment, porcelains was bonded with standard edgewise brackets and were stored in 37℃ saline for 24 hours. A universal testing machine was used to measure the shear bond strength of bracket to porcelain. The results were as follows : 1. The group which was treated with sandblasting or silane showed higher shear bond strength than the group which was treated with etching only. And the group which was treated with sandblasting, etching and silane showed the most highest shear bond strength(9.1-10.8 MPa). 2. No significant differences were found among bonding agents or concentrations of etching agent.

      • Sophora flavescens의 뿌리에서 유래한 Cholinesterase 저해 화합물

        장원희, 트란홍광, 김장훈, 양서영, 김영호 충남대학교 약학대학 의약품개발연구소 2021 藥學論文集 Vol.36 No.-

        Searching for cholinesterase inhibitory compounds from natural products is important to de- velop therapeutic agents for Alzheimer’s disease. Our previous research on the chemical components of Sophora flavescens roots resulted in the isolation of twelve flavonoids, kushenol E (1), maackiain (2), 8-prenylkaemperol (3), 8-prenylnaringenin (4), kushenol L (5), kushenol A (6), kushenol C (7), kushenol B (8), sophoraflavanone G (9), kushenol H (10), isoxanthohumol (11) and kurarinone (12) and their structures were elucidated by spectroscopic methods. Inhibitory effect of cholinesterase were tested using the Ellman's method. Most flavonoid compounds showed good inhibitory activities on cholinesterases. Kushenol E (1) and sophoraflavanone G (9) showed good inhibitory activities on acetylcholinesterase with IC50 values of 3.75 and 4.14 μM and butyrylcholinesterase with IC50 values of 2.00 and 0.75 μM, respectively. In addition, a kinetic analysis revealed that kushenol E (1) was non-competitive inhibitor with Ki value of 0.77 μM on acetylcholinesterase and 0.16 μM on butyrylcholinesterase, whereas sophoraflavanone G (9) was mixed type inhibitior with Ki value of 9.42 μM on acetylcholinesterase and 0.81 μM on butyrylcholinesterase. These findings suggest that flavonoid compounds from S. flavescens roots are potential cholinesterase inhibitors.

      • 四鹽化炭素로 肝障害를 誘導한 家兎에서의 抗結核劑의 排泄에 關한 硏究

        元章喜,權昌鎬 慶熙大學校 1984 論文集 Vol.13 No.-

        The drug metabolism of several antituberculosis was investigated in liver injuried rabbits. Antituberculosis drugs which used on this experiment were Rifampicin, Isoniazide and Pyrazinamide. The results were as follows. 1. Activities of sGOT and sGPT of rabbits induced liver injury by CCl_4 were increased (in sGOT, from 48.9 ± 1.48 units/ml to 370 ± 19 units/ml and in sGPT, from 42.5 ± 1.22 units/ml to 386 ± 32 units/ml) after the lapse of 24 hours from CCl_4 administration and then they were decreased gradually with the lapse of time (in sGOT, to 310 ± 25 units/ml and in sGPT, to 285 ± 26 units/ml after the lapse of 72 hours from CCl_4 administration). 2. The rifampicin which cxcreted mainly through bile at a small dose administration was excreted in urine at a large dose administration. 3. Each antituberculosis drugs which administrated on this experiment was excreted more quantity in urine of CCl_4 pretreated rabbits as compared with normal rabbits. particularly, Rifampicin was excreted far more quantity in urine of CCl_4 pretreated rabbits all the time. 4. From the above results, it was recognized that many notice about use of Antituberculosis drugs to liver injuried body must be required.

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