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      • KCI등재

        비밀분산 기반의 2-Subset Difference 브로드캐스트 암호시스템

        이재환(Jae Hwan Lee), 박종환(Jong Hwan Park) 한국방송·미디어공학회 2015 방송공학회논문지 Vol.20 No.4

        브로드캐스트 암호시스템은 한명의 송신자가 다수의 수신자에게 안전하게 메시지를 전송하는 기법이다. 제안된 브로드캐스트 암호시스템 중 가장 효율적인 것은 트리구조에서 Subset Difference(SD) 기법을 이용한 것으로, 이를 구체화하기 위해 유사난수생성기(PRG: Pseudo-Random Generator)와 비밀분산(SS: Secret Sharing) 방식을 이용한 두 가지 방법이 존재한다. 2-SD 기법은 SD 기법을 일반화하는 것으로 하나의 집합에서 두 개의 부분집합을 동시에 탈퇴시킬 수 있는 방법이다. 2-SD 기법의 장점으로는 SD 기법에 비해 전송량을 더 줄일 수 있다는 것이다. 그러나 현재까지 PRG나 SS 기반에서 2-SD 기법을 설계한 결과는 알려지지 않았다. 본 논문에서는 2014년 Jae Hwan Lee[9]등이 제시한 SS 기반의 SD 기법을 확장하여 SS 기반의 2-SD 기법을 설계한다. 제안된 기법은 기존 SS 기반의 SD 기법에서 요구하는 암호문 헤더 전송량의 약 25% 줄이는 효과가 있다. 또한 암호 이론적으로 본 논문의 결과는 증명가능한 2-SD 기법을 최초로 제시한 것이다. Broadcast encryption system is a cryptographic primitive that enables a sender to broadcast a message to a set of receivers in a secure channel. Out of previous proposed broadcast encryption systems, the most effective is the one that uses the Subset Difference(SD) method in a binary tree structure. The SD method has been realized by two underlying approaches: Pseudo-Random Generator(PRG) and Secret Sharing(SS). 2-SD method is the generalized version of the SD method by which two subsets of revoked receivers can be dealt with by one subset (in an SD-based broadcast encryption system). The primary advantage of the 2-SD method is to further reduce the size of transmission overhead, compared to the SD method. Until now, however, there is no known broadcast encryption system that is based on such a 2-SD technique using either PRG or SS basis. In this paper, we suggest a new 2-SD broadcast encryption system using the SS-based technique that was suggested by Jae Hwan Lee et al. in 2014[9]. The new system can reduce the size of ciphertext by 25% of the one in the previous SS-based broadcast encryption system. Also, on a theoretical note, ours is the first 2-SD broadcast encryption system that is provably secure.

      • KCI등재

        The Anti-obesity Effects of Gambi-hwan Extract on Obese Rats Induced by High-fat Diet through the Expression of UCP-1 and PPAR-${\delta}$

        Lee,,Beom-Joon,Ryu,,Jae-Hwan,Kim,,Jae-Wan,Park,,Jong-Hun,Park,,Jae-Woo The Society of Korean Medicine 2007 대한한의학회지 Vol.28 No.4

        Objective : Recently there are a lot of attempts to treat obesity through energy expenditure. Especially UCP-1 and PPAR-${\delta}$ is known to play a key role for energy dissipation through the increasing thermogenesis. Gambi-hwan extract is a traditional medicine made of herbs containing the polyunsaturate fatty acids related to the energy expenditure. It is expected to reduce the weight by means of the expression of UCP-1 and PPAR-${\delta}$. Meterial and Method : We divided 21 rats into 3 groups and assigned 8 rats respectively. The normal group was administered normal diet, the control group was administered high-fat diet, and the G50 group was administered high-fat diet with Gambi-hwan extracts50 mg/kg. And then the weights of body, food intake, the changes of lipids in blood stream, and the expressions of UCP-1 and PPAR-${\delta}$ on adipose tissues were measured respectively. Result : The reduction of body weight and the increasing tendency of expression of UCP-1 and PPAR-${\delta}$ mRNA were shown in G50 group. In the G50 group the Triglyceride level is decreased and the HDL-cholesterol level and the expression of PPAR-${\delta}$ and UCP-1 protein on Visceral adipose tissue were significantly increased. Conclusion : This result indicates that Gambi-hwan Extract upregulate the expression of UCP-1 and PPAR-${\delta}$ in adipose tissue, which may contribute to reducing the weight of adipose tissue.

      • KCI등재

        폐적(肺積) 폐옹(肺癰) 폐저(肺疽) 폐암(肺癌)에 관(關)한 문헌적(文獻的) 고찰(考察)

        한재수,오태환,정승기,이형구,Han,,Jae-Soo,Oh,,Tae-Hwan,Jung,,Sung-Gi,Rhee,,Hyung-Koo 대한한방내과학회 1991 大韓韓方內科學會誌 Vol.12 No.2

        This study has been carried out to investigate Pyu-Juk ( 肺積 ), Pyu-Ong ( 肺癰 ), Pyu-Ju ( 肺疽 ), Pyu-Am ( 肺癌 ) by referring to 56 literatures. The results were obtained as follows; 1. The treatllent-method of Pyu-Juk ( 肺積 ) are Ik Ki ( 益氣 ), SuI Yem Wha ( 洩陰火 ), So Juk ( 消積 ), Wha Juk ( 化積 ), Son Juk ( 損積 ), Ma Juk ( 摩積 ) Jo Chil Gi ( 調七氣 ), and herbs are Sik Bun Tang ( 息賁湯 ), Sik Bun Hwan ( 息賁丸 ), O Juk Hwan ( 五積丸 ), Ban ha Tang ( 半夏湯 ), Gil Gyung Tang ( 桔梗湯 ), Dae Chil Gi Tang ( 大七氣湯 ), Chil Gi Hwan ( 七氣湯 ) , Ga Gam Sik BlDl Hwan ( 加減息賁丸 ), Bil Rang San ( 檳郞散 ). 2. The treatment-method of Pyu-Ong ( 肺癰 ) Yang pyu ( 養肺 ), Yang Hyul ( 養血 ), Yang Gi ( 陽氣 ), Chung Geam Youn Pye ( 淸金潤肺 ), Hal Dam Bae Nong ( 豁痰排膿 ), Saeng Gi ( 生肌 ), herbs are Gil Gyung Tang ( 桔梗湯 ), Jung Ryuk Dae Jo Sa Pyu Tang ( ??大棗瀉肺湯 ), Chung Geom Wy Gyung Tang ( 千金 葦莖湯 ) Hwang Gi tang ( 黃嗜湯 ), Hyun Sam Chung Pyu Eum ( 玄蔘淸肺飮 ), Sip Mi Hwan ( 十味丸 ), Gil Gyung Baek San ( 桔梗白散 ), So Hong Eum ( 消膿飮 ), Sam Gi Bo Pyu Tang ( 蔘嗜補肺湯 ), sam Chul Gun Bi Tang ( 蔘朮健脾湯 ), Chung Pyu Gil Gyung Tang ( 淸肺桔梗湯 ), Yu Sung Hwan ( 如聖丸 ). 3. The treatment-method of Pyu-Ju ( 肺疽 ) are Be Bi ( 補脾 ), Bo Pyu ( 補肺 ), herbs are Hwang Gi Gum Jung Tang( 黃嗜補裨湯 ), lnSamBoPyuSan (人蔘補肺散) 4. The treatment-method of Pyu-Am ( 肺癌 ) are Bal Han ( 發汗 ), Chung Yul Hae Dok ( 淸熱解毒 ), Gang Hwa Do Dam ( 降火導痰 ), Hwa Rak Hwa a ( 和絡化瘀 ) Ik Pyu ( 益肺 ), Gun Bi ( 健脾 ), Ja Eum Yun Pyu ( 滋陰潤肺 ), Gi Hu Yang Bo ( 氣虛兩補 ), herbs are Gyul Yua Hae Dok Tang ( 莖熱解毒湯 ), Gang Hwa Jae ( 降火劑 ), Chil Yul Do Dam Tang ( 治熱導痰湯 ), Chong Ho Byul Gap Tang ( 靑蒿鱉甲湯 ), Ga gam Gil Gyung Tang ( 加減桔梗湯 ), Sang Mak San ( 生脈散), Yuk Mi Ji Hwang Tang ( 六味地黃湯 ), Baek Hap Go Geum Tang ( 百合固金湯 ), Dae Be Won Jun ( 大補元煎 ), Ga Mi Jae Che Bo Pyu Tang ( 加味載體補肺湯 ).

      • SCOPUSKCI등재

        Modulation of Melanin Synthesis by Amaranthus spp. L Seed Extract in Melan-a Cells

        ( Jae Ok Seo ), ( Moon Ho Do ), ( Jae Hak Lee ), ( Taek Hwan Lee ), ( Hussain Mustatab Wahedi ), ( Yong Un Park ), ( Sun Yeou Kim ) 한국생약학회 2016 Natural Product Sciences Vol.22 No.3

        Anti-melanogenic effects of amaranth (AT), one of the key source of squalene, were investigated in melanocytes. Amaranth seed powder was extracted with water and melan-a cells were treated with various concentrations of AT. By using HPLC, content of myo-inositol, one of potential active components, was measured in the crude extract of AT.AT reduced the melanin content in melan-a melanocytes and down-regulated melanogenic enzyme activity such as tyrosinase, TRP-1 and TRP-2. By regulating melanogenic enzyme activity, AT may be a potential natural source for whitening agent. Myo-inositol was detected in AT by HPLC and may be one of the active compounds from AT involved in the regulation of anti-melanogenesis. In this study, we demonstrated that AT has anti-melanogenesis properties. This new function of amaranth may be useful in the development of new skin-whitening products and its value as food.

      • KCI등재SCOPUS

        General Pharmacological Study of CJ-11828, an Amlodipine adipate

        Jae-Mook,CHOI,Sung-Hak,LEE,Il-Hwan,KIM,Jie-Eun,PARK,Choong,Sil,PARK,Yong,Sik,YOUN,Dong-Kwon,LIM,Sung-Hwan,CHO,Jun-Hwan,CHANG,Sun-Hee,DO,Eun-Joo,KIM,Young,Hoon,KIM 한국응용약물학회 2004 Biomolecules & Therapeutics(구 응용약물학회지) Vol.12 No.2

        This study was undertaken to evaluate the general pharmacological properties of CJ-11828, an amlodipine adipate, in experimental animals and in vitro system. CJ-11828 had no effects on general behavior, motor coordination, writhing syndromes, pentetrazol-induced chemoshock and electric shock in mice at dose levels of 3, 10, and 30 mg/kg, po. But there were decrease of body temperature, prolongation of sleeping time, and inhibition of intestinal activity in mice treated with CJ-11828 at doses of 10 and 30 mg/kg, po. CJ-11828 decreased the blood pressure in conscious dog at the dose level of 2 mg/kg, po, but it was expected as a result of pharmacological activity of CJ-11828. Any effect on respiratory system was not observed in conscious rat at doses of 3, 10, and 30mg/kg, po. The slight decrease in spontaneous motor activity was observed in mice treated with CJ-11828 at highdose, 30 mg/kg. In vitro experiments, CJ-11828 had no effect on agonists-induced contraction of isolated guinea pig ileum at 0.1, 1, and 10 μM. Based on these results, it was concluded that CJ-11828 had no pharmacological effect in these studies even up to the 36-fold anticipated clinical dose, 3 mg/kg.

      • KCI등재

        Hemiarthroplasty for Distal Humerus Fracture

        Jae-Man,Kwak,Erica,Kholinne,Yucheng,Sun,Gwan,Bum,Lee,Kyoung,Hwan,Koh,Jae-Myeung,Chun,In-Ho,Jeon 대한견주관절의학회 2018 대한견주관절학회지 Vol.21 No.3

        Background: Treatment of distal humerus fractures in osteoporotic elderly patients is often challenging. For non-reconstructible fractures with open reduction and internal fixation, total elbow arthroplasty (TEA) is an acceptable alternative. However, the relatively high complication rates and lifelong activity restrictions make TEA less ideal for elderly or low-demand patients. Efforts to identify or develop alternate procedures that benefit relatively young, high-demand patients have resulted in increased interest in hemiarthroplasty. This systematic review reports the clinical outcomes of hemiarthroplasty for distal humeral fractures. Methods: We systematically reviewed the databases of PubMed, Ovid MEDLINE, and Cochrane Library. All English-language studies published before June 2017 were considered for possible inclusion. Search terms included ‘distal humerus fracture' and ‘hemiarthroplasty'. Studies reporting outcomes (and a minimum of 1 year clinical follow-up) in human subjects after hemiarthroplasty (Latitude system) for distal humeral fractures were assessed for inclusion. Patient demographics, clinical and radiographic outcomes, and complications were recorded, and homogenous outcome measures were analyzed. Results: Nine studies with a total of 115 patients met the inclusion criteria. Among the included studies, the weighted mean follow-up time was 35.4 months. Furthermore, the weighted mean of the postoperative range of motion (107.6° flexion-extension, 157.5° for pronation-supination) and functional outcomes (Mayo elbow performance scores: 85.8, Disabilities of the Arm, Shoulder and Hand score: 19.6) were within the acceptable range. Conclusions: Our study indicates that hemiarthroplasty is a viable option for comminuted distal humerus fracture. Satisfactory functional outcomes were observed in most patients.

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