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      • 혼합 과일 발효주의 품질 특성 및 생리기능성

        신자원, 한상민, 박원종, 이종수 배재대학교 자연과학연구소 2014 自然科學論文集 Vol.25 No.1

        새로운 생리 기능성 과실주를 개발하고자 포도와 사과, 배, 복숭아 등을 이용하여 혼합 과일 발효주를 제조하여 이들의 품질특성과 생리기능성을 조사하였다. 혼합 과일 발효주의 에탄올 함량은 9.6% 이었고 총산함량과 휘발산 함량은 각각 0.73%와 0.086% 이었다. 또한 총 기호도는 신맛과 쓴맛이 살아있고 단맛이 적어 우수하였고 노화억제에 관련된 항산화 활성이 28.2% 이었고 항고혈압성 안지오텐신 전환효소 저해활성이 61.2% 로 우수하였다. To develop a new physiological functional wine, quality characteristics and its physiological functionality of the mixed fruit(Mf) wine were investigated. Ethanol contents of the Mf wine was 9.6%, and total acidity and volatile acid content were 0.73% and 0.086%, respectively. Anti-aging antioxidant activity of the Mf wine was 28.2% and anti-hypertensive angiotensin -converting enzyme inhibitory activity was very high 61.2%.

      • 위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

        김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

      • SCOPUSKCI등재
      • KCI등재

        색상 측정 기기를 이용한 복합레진 적층 수복과 단일 수복의 색상 비교 분석

        송영상,김자현,이빈나,장지현,장훈상,황윤찬,오원만,황인남 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2

        Objectives: This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers. Materials and Methods: For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering compositie resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin. Results: Color difference (△E*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at anythickness (△E* > 3.3). Conclusion: When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for chossing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel. (Restor Dent Endod 2012;37(2):84-89)

      • 자기공명영상을 이용한 정신분열병 환자의 뇌량크기 측정

        성상율,구자섭,조근호,원승희,이종훈,박종한 대한생물치료정신의학회 2004 생물치료정신의학 Vol.10 No.1

        Objectives : Nowadays many studies with MRI have reported structurai abnormalltles of corpus callosum of schizophrenic patients. However, the results are various and inconstant. In this study, we attempted to identify structural change of C O ~ U S cailosurn. Method : We measured the size of corpus callosum of the 24 schizophrenia patients (male 11, female 18) who were diagnosed by DSM-IV (19943, visited at department of psychiatry, catholic university hospital of Daegu from January 2002 to December 2003, by using midline sagittal slice of MRI. These results were compared with the size of corpus callosum of 25 controls (male 7, female 78). We divided corpus callosurn into 7 areas. We calculated and compared the areas of each subregion, mid-sagittal cerebral area, and entire corpus callosum. The results were analyzed by independent t-test. Result :When we compared subregion to corpus callosum adjusted wth mid-sagittal cerebral area, schlzoph-renia patients had significantly smaller genu (1.64k0.32 vs. 1.43k0.26 p<O.O5) and splenium (2.16f0.27 VS. 1.96+0.30 ; ~(0.05). Similarly, the ratio of total corpus callosum to midline sagittal cerebral area (%)(7.50*0.72 vs. 6.90t0.82 ~(0.05) was significantly smaller In schizophrenia than control group. Conclusion : In this study, we found significant differences in corpus callosum between schizophrenic patients and normal control group.

      • 담도에 국한되어 증상을 유발한 석회쓸개즙 2 예

        윤성우,이지영,하경호,이수경,한나,배효근,박선자 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

        Limy bile is a rare condition characterized by excessive precipitation of calcium carbonate in the gallbladder or bile duct. Recently we experienced two cases with obstructive jaundice in which limy bile in the common bile duct but not in the gallbladder for one case, and in the common bile duct and intra hepatic duct but not in the gallbladder for another case. The patients were treated by endoscopic sphincterotomy. Here, we report the cases and review the literature.

      • 자궁 경부에서 발생한 상피내 암종과 침윤성 암종의 간질 변화에 관한 병리조직학적 연구

        고성민,노광을,이민전,김용임,이미자,전호종,서재홍 조선대학교 1993 The Medical Journal of Chosun University Vol.18 No.2

        Connective tissue seems to be involved in malignancy by lytic processes as a crucial element in invasive growth. This looks relatively simple, but data have emerged that the stroma is not just a passive but rather an active participant. Recent advances in the borderland between cancer and connective tissue research have increasingly made it clear that the relationship between malignant tissue and its stroma is a very intricate one. The present study was performed in order to investigate the variety of stromal reactivity and alterations of basement membrane accompanying malignant growth and the distribution of Langerhans cells and T and B lymphocytes in cervical epithelium affected by intaepithelial neoplasia and invasive cervical carcinoma. The subjects in this were 14 cervicitis, 42 cervical intraepithelial neoplasia, 14 microinvasive cervical carcinoma and 14 invasive cervical carcinomas. A total of 84 formalin-fixed and paraffin-embedded specimens of normal, inflamed and neoplastic uterine cervix have been studied in order to correlate the epithelial changes with the expression of α-smooth muscle actin, S-100 protein, α_1-antichymotrypsin, lysozyme, LCA, CD20, UCHL1, OPD4, CD1, CD4, CD8, CD68 and typeⅣ collagen in stroma. The results of immunohistochemical and electron microscopical examinations yield virtually identical findings 1) The number of α-smooth muscle actin positive cells and the intensity of stain were related to the increasing grading of cervical intraepithelial neoplasia and invasive cervical carcinoma. 2) Normal cervix and cervical intraepithelial neoplasia grade Ⅰ and Ⅱ showed continuous basement membrane but invasive cervical carcinoma showed highly variable basement membrane deposition ranging from continuous to almost completely absent. 3) The cervical intraepithelial neoplasia Ⅲ and invasive cervical carcinoma showed an increase in spindle shaped Langerhans cells associated with increased numbers of stroma and intraepithelial lymphoid cells. The evaluation of collagen Ⅳ in basement membrane, S-100 protein and CD1 in Langerhans cells and α-smooth muscle actin in stromal cells of the uterine cervix may be an useful adjunct to diagnostic criteria of cervical intraepithrlial neoplasia and invasive cervical carcinoma, and may help understanding of the mechanisms of mesenchymal epithelial interactions during neoplasia.

      • 화훼식물의 분류와 區系에 관한 연구 : 부산.경남을 중심으로

        이옥자,문성기 慶星大學校 1998 論文集 Vol.19 No.1

        1. Horticulture plants for flowers searched in trading centers of flower and flower growing gardens of Pusan city and Kyungnam province amount to 115kinds and its taxonomical category were 3 divisions, 4 classes, 2 subclasses, 29 orders, 16 suborders, 43 families, 88 genera by Enger classification system. 2. According to the biogeographycal floristic regions of flower horticulture plants in this study Boreal region has 42 kinds(37.5%), Neotropical 31 kinds(21.5%), otherwise South African has 9 kinds(6.3%), Australian 6 kinds(4.2%), Antarctic 2 kinds(1.4%) in order. 3. In general Korean names of 40 kinds of flower horticulture plants were called as genus name of scientific name for example Korean name of "ACHIMENES" come from Achimenes and "ADIANTUM" come from Adiantum.

      • Papaverine이 저분극된 토끼 유두근의 수축력과 활동전압에 미치는 영향

        임인자,조성일,엄대용,이상돈 중앙대학교 의과대학 의과학연구소 1991 中央醫大誌 Vol.16 No.3

        In Partially deppolarized, isolated papillary muscle from rabbit heart, the effect of papaverine on contractile force and calcium mediated slow action potential was investigated. Results were as follows; 1. Papaverine induced the negative inotropic effect dose-dependently in the majority of preparations, although some preparations showed the opposite namely positive inotropic response. The significant correlation was found between the degree of depression in tension and increase that of in drug concentration. 2. The contractile force depressed by papaverine was restored by calcium(4 mM). 3. In partially depolarized papillary muscle, papaverine reduced slightly both action potential amplitude and upstroke velocity (dV/dt_max). The duration of action potential (duration of 90% repolarization) was also increased by papaverine in a dose-dependent manner. 4. The resting membrane potential was not altered in low concentrations (10^-7∼5X 10^-6M) of papaverine, however, it was significantly decreased in high concentration (10^-5∼5X 10^-5M) of the drug. The slightly increased overshoot potential was also observed in the above at high concentration range. From these results, it is suggested that in papillary muscle of rabbit heart, inhibitory effect of papaverine on the contractility may be attributable to its antagonistic action on the calcium current rather than its inhibitory effect on the phosphodiesterase activity. The local anesthetic property of the drug may also contribute to the papaverine induced decreases in both contractile force and upstroke velocity. The prolongation of action potential duration brought by papaverine appears to be induced not by increase in calcium currents but by a decrease in K^+ conductance.

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