천식에서 관련 유전자들 사이의 상호작용과 천식에대한 영향

이준혁,박성우,장안수,박춘식 순천향대학교 의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

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근로자의 이해관계자 참여수준에 관한 인식

송준호,김훈식 안양대학교 복지행정연구소 1999 福祉行政硏究 Vol.15 No.-

This article is an empirical study on participation level of stakeholders in korean companies. 283 questionnaires were analyzed which are composed of 12 items respectively. These items are classified stakeholders with six categories : employees, unions, professional groups, subcontractors, local residents and customers. As a result, employees perceive as follows : (1) The participation level of stakeholders is 3.1850 point in a survey of 6 polnt scale. This means negative cognition to participation level here. (2) That of large companies is higher than that of small-medium companies. (3) That of manufactured companies is relativdy higher than that of non-manufactured companies. (4) That of high profitable companies is slightly higher than that of low profitable companies. (5) That of male, clerk and high position employees are higher than that of female, production worker and low position employees.

노동조합 전임자제도의 개선방향

김훈식,송준호 안양대학교 사회과학연구소 2000 社會科學硏究 Vol.7 No.-

The trade unions and the managements are heavily conflicting owing to a matter concerning a payment of wage & salary for local union officers by their employers in each individual companies. Korean labor law now states that a payment of wage & salary by their employer is unfair labor practice. Therefore, the unions insist on amendment of the provision, the managements don't agree with the daim. This artide suggest some proposals for reasonable settlement between the unions and the managements as follows : 1) A payment of wage & salary for local union representatives must be decided by two parties, not a labor law's regulation. 2) The number of full-time local union officers need to be decreased, but on the other hand the number of part-timer must be increased. 3) It is necessary that the trade unions make efforts to highten the autonomy and the efficiency of operation. 4) Specific collective bargaining agreement on all types of compensation for union officers had better to be made in each companies respectively.

硬化性 物質(Sotradecol^ⓡ과 Tetracycline)을 利用한 腎動脈塞栓에 關한 實驗的 硏究

趙俊植,李秉喆 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

Transcatheter embolization. of renal artery using Gelfoam^ⓡ soaked in Sotradecol^ⓡ sodium tetradecyl sulfate) and Tetracycline solution in rabbits was performed to evaluate the effect of intra-arterial injection. Selective renal arteriography was done at 15 minutes, 1 week and 4 weeks after embolization. The rabbits were subsequently sacrificed and histopathologic examination performed. The result were as follows: 1. Initial segmental occlusion was sustained in 11 of 16 cases that performed follow-up angiography. Recanalized vessels showed irregular narrowing and marked decrease in number in 2 of 5 cases and progressive occlusion of segmental and proximal renal artery in 3 of 5 cases. 2. The infarcted kidneys were swollen and enlarged at 1 week. There were resulted in shrinkage of infarcted kidney and compansatory hypertrophy of opposite kidney depending on intitial extent of infarcted area at 4 weeks. 3. After embolization, minute collateral vessels were developed in 10 of 16 cases without remarkable nephrogram in infarcted area. 4. The effect of, Tetracycline seemed, to be similar to that of Sotradecol in producing arterial occlusion. 5% Tetracycline was :more injurious than 2.5% concentration in occlusion of renal artery. 5. Abscess formation within infarcted kidney was occurred in two cases using Sotradecol but not occurred in cases using Tetracycline. 6. Sotradecol and Tetracycline were the effective agents of producing persistent renal infarction with peripheral as well as central occlusion. It was consirdered that intra-arterial injection of Tetracycline was the available mean of producing persistent renal artery embolization.

복부농양 및 액체저류의 경피적 카테타 배액술

조준식 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

Percutaneous catheter drainage using a combination of US, CT and fluoroscopic guidance has become the treatment of choice for various abdominal abscesses and fluid collections. It is an important alternative to surgical treatment because of its high success rate, low mortality rate and low complication. The Author analyzed the results of percutaneous catheter drainage in 30 patients with abdominal abscesses and fluid collections at Chungnam National University Hospital from May 1986 to Aug. 1988. The results were as follows: 1. Successful drainage of the collection with avoidance of operation was achieved in 24/30 (80%) patients and partial success in 3 patients among 6 failures and recurrences 2. There were 2 failures and 4 recurrence and these were due to phlegmon, organized tissue, multiplicity, fistulae, or underlying tumor. 3. Comlication was minor in most cases 4. The overall, complete and partial success rate was 90%, failure rate was 6.7% and recurrent rate was 13.3%.

위에 생긴 이소성 췌장의 진단에 있어 경구 조영제로 물을 사용한 후 조영증강 역동적 CT의 가치

조준식,신경숙 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

To describe the usual and unusual CT findings of heterotopic pancreatic of the stomach and to evaluate the usefulness of dynamic contrast-enhanced CT with water as an oral contrast agent in diagnosing heterotopic pancreas We retrospectively reviewed CT findings in 10 patients with pathologically proved gastric heterotopic pancreas by operation (n=9) or endoscopic resection (n=1). In three patients, conventional CT with diluted Gastrografin solution as an oral contrast agent was performed. In seven patients, two-phase dynamic CT scans after ingestion of 600-800 ml of water were obtained in the early phase and equilibrium phase. Dynamic CT findings of heterotopic pancreas were correlated with histopathologic findings. All 10 heterotopic pancreatic rests were detected with conventional CT or dynamic CT. In seven cases who underwent dynamic CT after ingestion of water, highly enhanced mucosal layers overlying the lesions were identified and all lesions were well delineated in the submucosal layer In four of these seven cases, heterotopic pancreas showed high enhancement similar to that of adjacent normal pancreatic enhancement in the early phase of dynamic CT. The usual CT findings of gastric heterotopic pancreas were oval-shaped submucosal masses (<3cm) in the gastric antrum. The unusual CT findings were infiltrating heterotopic pancreas into the muscle layer in one, cystic dilatation of heterotopic pancreatic ducts in two, and malignant change with mucin secreting cystadencoarcinoma in one. Gastric heterotopic pancreas usually showed oval-shaped submucosal masses (<3cm) in the gastric antrum with high enhancement similar the that of pancreatic enhancment in the early phase of dynamic CT. Our results suggest that contrast-enhanced dynamic CT after ingestion of water may be helpful in diagnosing gastric heterotopic pancreas.

두경부에서 생긴 림프종에서 EBV와 HTLV-1의 검색

박준식,정효순,권성우,이상숙 경북대학교 병원 2003 경북대학교병원의학연구소논문집 Vol.7 No.1

Background and Objectives : Extranodal non-Hodgkin's lymphoma(NHL) of the head and neck(H&N) accounts for 10-20% of all cases of NHL. Despite their frequency, the cause of these lymphomas is still poorly understood. Recently, the role of viral origin in NHLs, including Epstein-Barr virus(EBV), as the main cause of sinonasal lymphomas of T/NK cell phenotype and HTLV-1 as a cause of acute T-cell lymphoma/leukemia has been well documented. We investigated the clinicopathologic findings, immunophenotypic profile, and status of EBV and HTLV-1 DNA of patients with H&N lymphoma. Materials and Methods : Twenty-seven patients with NHL of H&N region were studied. There were 15 males and 12 females with the median age of 50 years. All patients were reclassified according to the Working formulation(WF) and REAL classification. EBV genome DNA and HTLV-1 RNA were surveyed by PCR assay using formalin-fixed and paraffin-embedded tissue blocks. Results : The tonsil was the most commonly involved site(44.4%) followed by nasal cavity(18.5%), nasopharynx(18.5%) and orbit(7.4%). Immunophenotyping revealed 19 cases of B cell lineage, 7 cases of T cell lineage and one case of null cell type. Most of B-cell lymphomas were diffuse large cell lymphomas(58%). Tonsillar lymphomas were all B-cell origin. Four of the five nasal cavity lymphomas and one nasopharyngeal lymphoma showed an angiocentric T/NK cell phenotype with strong association with EBV. EBV genome was detected in 15 of 26 H&N NHLs(57.7%). Seven of 19 B-cell lymphomas(36.8%) and all T/NK or null cell type lymphomas were positive for EBV DNA. However, there was no HTLV-1 positive cases found. Conclusions : It could be concluded that the high incidence of EBV of angiocentric T/NK-cell lymphomas of the nasal cavity may indicate a probable role of EBV in the development of these lymphomas.

진행위암의 수술전 병기결정에서 문맥기 나선식 CT의 유용성 : Usefulness of Helical CT during the Portal Venous Phase

조준식,신경숙 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

The purpose of this study was to evaluate the effect of helical CT during the portal venous phase after oral ingestion of water in the preoperative staging of advanced gastric carcinomas. Of the patients underwent helical CT scanning for preoperative staging of gastric carcinoma, 70 patients with pathologically proved advanced gastric carcinomas were selected in this study. The patients ingested 600-800m1 of water as a oral contrast agent before CT scanning. A total 130150ml of nonionic contrast material was administered at the rate of 4ml/s. We obtained portal venous phase images at 60 s and equilibrium phase images at 3 min after the start of bolus administration of intravenous contrast material. Two-phase CT findings were prospectively evaluated and correlated with histopathologic findings according to TNM classification. The primary tumors were detected on CT scans in 69 (98.5%) of 70 cases. The accuracy of CT for T staging was 74.3% (52 of 70 cases). T staging was understaged in 13 cases (18.6%) and overstaged in five (7.1%). The accuracy for N staging was 67.1% (47 of 70 cases). N staging was understaged in 16 cases (22.9%) and overstaged in seven (10%). Our results suggest that helical CT during the portal venous phase can improve the accuracy of CT in the preoperative staging of advanced gastric carcinomas.

급성 폐쇄성 담관염의 치료에서 경피적 담배액술의 역할

조준식,김충현 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

Acute obstructive cholangitis may manifest clinically from mild to severe suppurative form. Percutaneous biliary drainage (PBD) provide alternative for nonoperative biliary decompression in acute obstructive cholangitis. We analyzed our experience of PBD in 35 patients with acute obstructive cholangitis. The underlying diseases were 26 maliganant tumors and 9 benign diseases. Acute suppurative cholangitis occurred in 11 of 35 patients and the causes were 6 benign disases due to bile duct stone and 5 maliganant tumors. PBD was performed succssfully in 32 of 35 patients, 29 patients were managed effectively, partial success in 3 patients, and failed in 3 patients as a result of septic shock and biliary-portal venous fistula. Palliative PBD for advanced malignant tumor underwent in 19 patients and preoperative PBD underwent in 13 patients. Successful surgery after effective biliary decompression was performed in 12 of 13 patients who underwent preoperative PBD. This analysis suggest that PBD is initial treatment of choice for acute suppurative cholangitis and can be performed safely in acute obstructive cholangitis for palliative or preoperative management.

비정규직 근로자의 고용실태와 개선과제

김훈식,송준호 안양대학교 사회과학연구소 2001 社會科學硏究 Vol.8 No.-

ABSTRACT Since the economic crisis in late 1997, the ratio of non-standard workers to all employees was heavily increased from 41.3% lo 51.7%. Therefore, the interest groups like companies, employees end the government respond positively or negatively. This paper give you some attractive proposals on employment matters of non-standard workers as follower : flexibility of employment period, enlargement of social insurances, practice of equal work & equal wage, abolition of premium in favor of standard workers, design of of employment portfolio, upgrde of working conditions, opportunity of transfer from non-standard worker to standard employees.