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- 저자 : JOSHI, Yogesh (검색결과 634 건)
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JOSHI, Santosh,UPRETI, Dalip K.,THANH, Nguyen Thi,NGUYEN, Anh Dong,HUR, Jae-Seoun Cambridge University Press 2017 The Lichenologist Vol.49 No.3
<B>Abstract</B><P>The lowland area of southern Vietnam contains a high diversity of corticolous, crustose lichens, particularly in the family <I>Graphidaceae</I>. Two species, <I>Acanthothecis verrucosa</I> S. Joshi, Upreti & Hur and <I>Graphis exuta</I> S. Joshi, Upreti & Hur, are described new to science. <I>Acanthothecis verrucosa</I> is characterized by a verrucose, olive green thallus containing irregular to shortly lirellate apothecia, hyaline to brownish proper exciple apically lined by robust periphysoids, muriform ascospores, 30-70 × 15-20 μm, and the presence of psoromic and subpsoromic acids. <I>Graphis exuta</I> is characterized by a smooth, greenish white thallus, simple lirellae lacking thalline margin, entire labia coarsely white pruinose towards slit, muriform ascospores, 20-35×10-13 μm, and norstictic acid in the thallus. A new name, <I>Acanthothecis yokdonensis</I> S. Joshi & Hur, is proposed here for the species <I>Acanthothecis salazinica</I> S. Joshi & Hur, a later homonym of <I>A. salazinica</I> van den Boom & Sipman. In addition, 34 species from Vietnam are newly reported. A world key to the group of <I>Graphis</I> species characterized by short, simple and sessile lirellae lacking or with basal thalline margins (<I>nuda</I>-morph) is presented.</P>
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Joshi Deepa,Kashmira J.Gohil,Joshi Deepa 대한약침학회 2023 Journal of pharmacopuncture Vol.26 No.1
Objectives: Murraya paniculata (family-Rutaceae), popularly known as orange jasmine, is the most important evergreen plant. The Rutaceae family is economically significant due to its diverse edible fruits and essential oils. Methods: Murraya paniculata extracts (MPE) of leaf have been shown to include phenolic compounds, highly oxygenated flavonoids, flavanones, sesquiterpenoids, polymethoxy glycosides, and coumarins. Cyclocitral, methyl salicylate, trans-nerolidol, cubenol, isogermacrene, -cadinol, and cubeb-11-ene are all abundant in MPE. The usages of various parts of this plant, such as bark, leaves and flower, as a remedy for a variety of ailments as widely recorded in the traditional literature. The plant has anti-diabetic, anti-obesity, antibacterial, anti-implantation, anti-oxidative, cytotoxic, anti-diarrheal, antidepressant and anti-anxiety properties and many others. Results: The goal of the review is to reignite interest in this potential plant, encouraging researchers to continue their research in order to uncover novel therapeutic compounds for the treatment and management of a range of infections. The current review provided a comprehensive overview of this traditional unique plant. Conclusion: The review paves a way for exploring its active chemical elements with substantial pharmacological values further for potential benefits of mankind.
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Joshi, Pankaj,Joshi, Rakhi Kumari,Kim, Woo Jin,Lee, Sang-Ah Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Context: Insulin-like growth factor peptides play important roles in regulating cell growth, cell differentiation, and apoptosis, and have been demonstrated to promote the development of colorectal cancer (CRC). Objective: To examine the association of insulin-related biomarkers including insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3) and C-peptide with CRC risk and assess their relevance in predictive models. Materials and Methods: The odds ratios of colorectal cancer for serum levels of IGF-1, IGFBP-3 and C-peptide were estimated using unconditional logistic regression models in 100 colorectal cancer cases and 100 control subjects. Areas under the receiving curve (AUC) and integrated discrimination improvement (IDI) statistics were used to assess the discriminatory potential of the models. Results: Serum levels of IGF-1 and IGFBP-3 were negatively associated with colorectal cancer risk (OR=0.07, 95%CI: 0.03-0.16, P for trend <.01, OR=0.06, 95%CI: 0.03-0.15, P for trend <.01 respectively) and serum C-peptide was positively associated with risk of colorectal cancer (OR=4.38, 95%CI: 2.13-9.06, P for trend <.01). Compared to the risk model, prediction for the risk of colorectal cancer had substantially improved when all selected biomarkers IGF-1, IGFBP-3 and inverse value of C-peptide were simultaneously included inthe reference model [P for AUC improvement was 0.02 and the combined IDI reached 0.166% (95 % CI; 0.114-0.219)]. Conclusions: The results provide evidence for an association of insulin-related biomarkers with colorectal cancer risk and point to consideration as candidate predictor markers.
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Joshi, Surabhi,Gowda, Ashwini Shivananje,Joshi, Chintan Korean Academy of Periodontology 2013 Journal of Periodontal & Implant Science Vol.43 No.6
Purpose: In this study, the effect of calcium sodium phosphosilicate (NovaMin) desensitizing agent, which is a powder-based system, and hydroxyethyl methacrylate and glutaraldehyde (Gluma desensitizer), which is liquid-based system, on dentinal tubule occlusion was analyzed by scanning electron microscope. The effects of the above two along with one control group were compared to determine the more effective method of sealing the dentinal tubules after initial application. Methods: Twenty specimens were allocated to each of 3 groups: Control, Gluma desensitizer, and NovaMin. Two additional samples were also prepared and treated with Gluma and NovaMin; these samples were longitudinally fractured. The specimens were prepared from extracted sound human premolars and were stored in 10% formalin at room temperature. The teeth were cleaned of gross debris and then sectioned to provide one to two dentin specimens. The dentin specimens were etched with 6% citric acid for 2 minutes and rinsed in distilled water. Control discs were dried, and the test discs were treated with the desensitizing agents as per the manufacturer's instructions. The discs as well as longitudinal sections were later analyzed under the scanning electron microscope. The proportions of completely occluded, partially occluded, and open tubules within each group were calculated. The ratios of completely and partially occluded tubules to the total tubules for all the groups was determined, and the data was statistically analyzed using nonparametric tests and statistical significance was calculated. Results: NovaMin showed more completely occluded tubules ($0.545{\pm}0.051$) while Gluma desensitizer showed more partially occluded tubules ($0.532{\pm}0.075$). The differences among all the groups were statistically significant ($P{\leq}0.05$). Conclusion: Both materials were effective in occluding dentinal tubules but NovaMin appeared more promising in occluding tubules completely after initial application.
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Joshi, Y.C.,Saingar, Shalini,Kavita, Kavita,Joshi, P.,Kumar, Rajesh Korean Chemical Society 2011 대한화학회지 Vol.55 No.4
The synthesis of biologically active 1H-1,4-diazepines 4a-d and 3H-1,5-benzodiazepines 5a-d in good yields, from the heterocyclization reaction of 2-(4-methylthio benzenesulfonyl)-1,3-dimethyl/1-methyl-3-phenyl/1,3-diphenyl/1-methyl-3-ethoxy propane-1,3-dione 3a-d with ethylenediamine (EDA) and o-phenylenediamine (o-PDA), respectively, in the presence of silica sulfuric acid (SSA) is described. The novel ${\beta}$-diketones/${\beta}$-ketoesters 3a-d were synthesized by the condensation reaction of 4-methylthiobenzenesulfonyl chloride 1 with various ${\beta}$-diketones/${\beta}$-ketoesters 2a-d. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral studies. The compounds 4a-d and 5a-d have been screened for antimicrobial, antifungal and anthelmintic activity. Silica sulfuric acid (SSA)를 이용하여 ethylenediamine (EDA)과 o-phenylenediamine (o-PDA)을 2-(4-methylthio benzenesulfonyl)-1,3-dimethyl/1-methyl-3-phenyl/1,3-diphenyl/1-methyl-3-ethoxypropane-1,3-dione 3a-d과의 헤테로고리화 반응을 통하여 좋은 생리활성을 나타내는 1H-1,4-diazepines 4a-d과 3H-1,5-benzodiazepines 5a-d을 좋은 수율로 합성하였다. 이 반응에서 ${\beta}$-diketones/${\beta}$-ketoesters 3a-d는 4-methylthiobenzenesulfonyl chloride 1과 다양한 ${\beta}$-diketones/${\beta}$-ketoesters 2a-d과의 축합반응으로 합성하였으며, 합성한 4a-d와 5a-d 화합물들에 대해서 fantimicrobial, antifungal 및 anthelmintic 활성을 측정하였다.
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Raman spectroscopic analysis to detect olive oil mixtures in argan oil
Rahul Joshi,조병관,Ritu Joshi,Santosh Lohumi,Mohammad Akbar Faqeerzada,Hanim Z Amanah,이재영,모창연,이훈수 충남대학교 농업과학연구소 2019 Korean Journal of Agricultural Science Vol.46 No.1
Adulteration of argan oil with some other cheaper oils with similar chemical compositions has resulted in increasing demands for authenticity assurance and quality control. Fast and simple analytical techniques are thus needed for authenticity analysis of high-priced argan oil. Raman spectroscopy is a potent technique and has been extensively used for quality control and safety determination for food products In this study, Raman spectroscopy in combination with a net analyte signal (NAS)-based methodology, i.e., hybrid linear analysis method developed by Goicoechea and Olivieri in 1999 (HLA/GO), was used to predict the different concentrations of olive oil (0 - 20%) added to argan oil. Raman spectra of 90 samples were collected in a spectral range of 400 - 1400 cm-1, and calibration and validation sets were designed to evaluate the performance of the multivariate method. The results revealed a high coefficient of determination (R2) value of 0.98 and a low root-mean-square error (RMSE) value of 0.41% for the calibration set, and an R2 of 0.97 and RMSE of 0.36% for the validation set. Additionally, the figures of merit such as sensitivity, selectivity, limit of detection, and limit of quantification were used for further validation. The high R2 and low RMSE values validate the detection ability and accuracy of the developed method and demonstrate its potential for quantitative determination of oil adulteration.
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Surabhi Joshi,Ashwini S,Chintan Joshi 대한치주과학회 2013 Journal of Periodontal & Implant Science Vol.43 No.6
Purpose: In this study, the effect of calcium sodium phosphosilicate (NovaMin) desensitizing agent, which is a powder-basedsystem, and hydroxyethyl methacrylate and glutaraldehyde (Gluma desensitizer), which is liquid-based system, on dentinaltubule occlusion was analyzed by scanning electron microscope. The effects of the above two along with one control groupwere compared to determine the more effective method of sealing the dentinal tubules after initial application. Methods: Twenty specimens were allocated to each of 3 groups: Control, Gluma desensitizer, and NovaMin. Two additionalsamples were also prepared and treated with Gluma and NovaMin; these samples were longitudinally fractured. The specimenswere prepared from extracted sound human premolars and were stored in 10% formalin at room temperature. The teethwere cleaned of gross debris and then sectioned to provide one to two dentin specimens. The dentin specimens were etchedwith 6% citric acid for 2 minutes and rinsed in distilled water. Control discs were dried, and the test discs were treated withthe desensitizing agents as per the manufacturer’s instructions. The discs as well as longitudinal sections were later analyzedunder the scanning electron microscope. The proportions of completely occluded, partially occluded, and open tubules withineach group were calculated. The ratios of completely and partially occluded tubules to the total tubules for all the groups wasdetermined, and the data was statistically analyzed using nonparametric tests and statistical significance was calculated. Results: NovaMin showed more completely occluded tubules (0.545±0.051) while Gluma desensitizer showed more partiallyoccluded tubules (0.532±0.075). The differences among all the groups were statistically significant (P≤ 0.05). Conclusion: Both materials were effective in occluding dentinal tubules but NovaMin appeared more promising in occludingtubules completely after initial application.
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Evaluation of benzene residue in edible oils using Fourier transform infrared (FTIR) spectroscopy
Ritu Joshi,조병관,Santosh Lohumi,Rahul Joshi,이재영,이훈수,모창연 충남대학교 농업과학연구소 2019 Korean Journal of Agricultural Science Vol.46 No.2
The use of food grade hexane (FGH) for edible oil extraction is responsible for the presence of benzene in the crude oil. Benzene is a Group 1 carcinogen and could pose a serious threat to the health of consumer. However, its detection still depends on classical methods using chromatography which requires a rapid non-destructive detection method. Hence, the aim of this study was to investigate the feasibility of using Fourier transform infrared (FTIR) spectroscopy combined with multivariate analysis to detect and quantify the benzene residue in edible oil (sesame and cottonseed oil). Oil samples were adulterated with varying quantities of benzene, and their FTIR spectra were acquired with an attenuated total reflectance (ATR) method. Optimal variables for a partial least-squares regression (PLSR) model were selected using the variable importance in projection (VIP) and the selectivity ratio (SR) methods. The developed PLS models with whole variables and the VIP- and SR-selected variables were validated against an independent data set which resulted in R2 values of 0.95, 0.96, and 0.95 and standard error of prediction (SEP) values of 38.5, 33.7, and 41.7 mg/L, respectively. The proposed technique of FTIR combined with multivariate analysis and variable selection methods can detect benzene residuals in edible oils with the advantages of being fast and simple and thus, can replace the conventional methods used for the same purpose.
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