Clinical anatomy of the maxillary sinus: application to sinus floor augmentation

Joe Iwanaga,Joe Iwanaga,Charlotte Wilson,Stefan Lachkar,Krzysztof A. Tomaszewski,Jerzy A. Walocha,R. Shane Tubbs 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.1

The anatomy of the maxillary sinus, especially its vascular anatomy, and its relationships with the teeth and alveolar processes have been well documented. The development of cone-beam computed tomography has resulted in dentists being more familiar with maxillary sinus floor augmentation procedures. This paper aims to revisit the classic anatomy of the maxillary sinus and review the newly published literature in order to help dentists diagnose in more detail and perform safer surgery of the maxillary sinus.

Stafne bone cavity: a rare cadaveric case report

Joe Iwanaga,Joe Iwanaga,T. L. Wong,Shogo Kikuta,R. Shane Tubbs 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.3

The Stafne bone cavity (SBC), also called the static bone cavity, salivary inclusion cyst, latent cyst, and lingual bone defect is an asymptomatic bony defect that is commonly located inferior to the mandibular canal and slightly above the inferior border of the mandible. It is rare to see the actual bony defect in the cadaver because of its relatively low incidence of 0.1% to 6.06%. We report a unilateral SBC found in a 76-year-old at death male Caucasian cadaver and involving the right mandible. The SBC was oval in shape with a smooth surface and measured 10.8×6.0 mm. The SBC was continuous with the right mylohyoid groove. Since actual photographs of the SBC are lacking in the literature, this report might provide additional insight for better understanding the SBC.

Quantitative analysis of the effect of triglyceride alkyl-chain length on the partitioning of highly lipophilic compounds to the mesenteric lymph in intestinal cells

Iwanaga, Kazunori,Kawabata, Yutaka,Miyazaki, Makoto,Kakemi, Masawo 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

The purpose of this study was to quantitatively clarify the effect of alky-chain length of a triglyceride in an emulsion on the partitioning of highly lipophilic compounds into the lymph fluid after their oral administration. Highly lipophilic anthraquinone derivatives were orally administered in emulsions to rats. Emulsions composed of long-, medium-, and short-chain triglycerides (LCT, MCT, and SCT emulsions, respectively) were used. The concentrations of the compounds in plasma and lymph fluid were periodically determined and their partitioning to the lymph was calculated using a mathematical model. Intestinal absorption of all compounds was enhanced and the plasma concentrations of the compounds were found to be in the following order: LCT emulsion>MCT emulsion>SCT emulsion. The amounts of each compound recovered in the lymph were not in agreement with their lipophilicity. Quantitative analysis revealed that the partitioning of the compounds to the lymph may be determined by the solubility of the compound in the triglyceride in the form of an emulsion and the amount of triglyceride transferred to the lymph fluid. These results suggest a possibility that the amount of a compound absorbed via the lymph route after oral administration can be quantitatively controlled by the formulations.

Recent Advances in the Innate Immunity of Invertebrate Animals

Iwanaga, Sadaaki,Lee, Bok Luel 한국생화학분자생물학회 (구 한국생화학회) 2005 BMB Reports Vol.38 No.2

Invertebrate animals, which lack adaptive immune systems, have developed other systems of biological host defense, so called innate immunity, that respond to common antigens on the cell surfaces of potential pathogens. During the past two decades, the molecular structures and functions of various defense components that participated in innate immune systems have been established in Arthropoda, such as, insects, the horseshoe crab, freshwater crayfish, and the protochordata ascidian. These defense molecules include phenoloxidases, clotting factors, complement factors, lectins, protease inhibitors, antimicrobial peptides, Toll receptors, and other humoral factors found mainly in hemolymph plasma and hemocytes. These components, which together compose the innate immune system, defend invertebrate from invading bacterial, fungal, and viral pathogens. This review describes the present status of our knowledge concerning such defensive molecules in invertebrates.

Recent Advances in the Innate Immunity of Invertebrate Animals

Iwanaga, Sadaaki,Lee, Bok-Luel Korean Society for Biochemistry and Molecular Biol 2005 Journal of biochemistry and molecular biology Vol.38 No.2

Invertebrate animals, which lack adaptive immune systems, have developed other systems of biological host defense, so called innate immunity, that respond to common antigens on the cell surfaces of potential pathogens. During the past two decades, the molecular structures and functions of various defense components that participated in innate immune systems have been established in Arthropoda, such as, insects, the horseshoe crab, freshwater crayfish, and the protochordata ascidian. These defense molecules include phenoloxidases, clotting factors, complement factors, lectins, protease inhibitors, antimicrobial peptides, Toll receptors, and other humoral factors found mainly in hemolymph plasma and hemocytes. These components, which together compose the innate immune system, defend invertebrate from invading bacterial, fungal, and viral pathogens. This review describes the present status of our knowledge concerning such defensive molecules in invertebrates.

Extended crossing fibers of the mentalis muscle attaching to the contralateral mandible

Joe Iwanaga,Mi-Sun Hur,Shogo Kikuta,Soichiro Ibaragi,R. Shane Tubbs 대한해부학회 2021 Anatomy & Cell Biology Vol.54 No.4

Fibers of the facial muscles occasionally extend, cross the midline, and connect to surrounding structures on the contralateral side, perhaps enabling the mouth to make more delicate movements and generate more facial expressions. This case report describes a variant in which the extended fibers of the mentalis crossed the midline and indicates the relationship of these fibers to the surrounding structures. Some of the deepest fibers of the mentalis descended inferomedially and crossed transversely just below the chin prominence to attach to the periosteum of the mandible on the contralateral side. The variation presented in this study shed light on the interactions of the mentalis with the surrounding muscles.

The sphenopalatine vein: anatomical study of a rarely described structure

Joe Iwanaga,Eric Pineda,Yusuke Miyamoto,Grzegorz Wysiadecki,Samir Anadkat,R. Shane Tubbs 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.2

Although in counterpart, the sphenopalatine artery (SPA), has been well described in the medical literature, thesphenopalatine vein (SPV) has received scant attention. Therefore, the present anatomical study was performed. Additionally, we discuss the variations, embryology, and clinical significance of the SPV. Adult cadaveric specimens underwent dissection of the SPV. In addition, some specimens were submitted for histological analysis of this structure. The SPV was found to drain from the sphenoidal sinus and nasal septum. Small tributaries traveled through the nasal septum with the posterior septal branches of the SPA and nasopalatine nerve. The SPA and SPV were found to travel through the sphenopalatine foramen and another tributary was found to perforate the medial plate of the pterygoid process and to connect to the pterygoid venous plexus which traveled lateral to the medial plate of the pterygoid process. The vein traveled through the posterior part of the lateral wall of the nasal cavity with the posterior lateral nasal branches of the SPA and the lateral superior posterior nasal branches of the maxillary nerve. To our knowledge, this is the first anatomical study on the SPV in humans. Data on the SPV provides an improved anatomical understanding of the vascular network of the nasal cavity. Developing a more complete picture of the nasal cavity and its venous supply might help surgeons and clinicians better manage clinical entities such as posterior epistaxis, cavernous sinus infections, and perform endoscopic surgery with fewer complications.

Quantitative analysis of the effect of triglyceride alkyl-chain length on the partitioning of highly lipophilic compounds to the mesenteric lymph in intestinal cells

Kazunori Iwanaga,Yutaka Kawabata,Makoto Miyazaki,Masawo Kakemi 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

The purpose of this study was to quantitativelyclarify the effect of alky-chain length of a triglyceride in anemulsion on the partitioning of highly lipophilic compoundsinto the lymph fluid after their oral administration. Highly lipophilic anthraquinone derivatives were orallyadministered in emulsions to rats. Emulsions composed oflong-, medium-, and short-chain triglycerides (LCT, MCT,and SCT emulsions, respectively) were used. The concentrationsof the compounds in plasma and lymph fluidwere periodically determined and their partitioning to thelymph was calculated using a mathematical model. Intestinalabsorption of all compounds was enhanced and theplasma concentrations of the compounds were found to bein the following order: LCT emulsion[MCT emulsion[SCT emulsion. The amounts of each compound recoveredin the lymph were not in agreement with their lipophilicity. Quantitative analysis revealed that the partitioning of thecompounds to the lymph may be determined by the solubilityof the compound in the triglyceride in the form of anemulsion and the amount of triglyceride transferred to thelymph fluid. These results suggest a possibility that theamount of a compound absorbed via the lymph route afteroral administration can be quantitatively controlled by theformulations.

Development of a Compensatory Control System to Reduce Hysteresis of Steel Level Control Equipment in Continuous Casting Mold

T. Iwanaga,I. Kosakai,K. Ebina,M. Itashiki,K. Furukawa 대한전자공학회 1991 대한전자공학회 학술대회 Vol.1991 No.01

Evolving Adaptive Group Behavior in a Multi-Robot System

Saori Iwanaga,Kazuhiro Ohkura,Tomoya Matsuda 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

The field of multi-robot systems is sometimes called swarn robotics when the systems consist of many simple autonomous robots. However, each robot is usually assumed to have no learning mechanism for adapting to an embedded changing environment. Therefore, collective behavior is expected to emerge in the system only through interactions among the robots. This implies that they cannot be coordinating as a group. In this study, an evolutionary robotics approach is applied empirically to a multi-robot system to realize autonomous task allocation behavior as a kind of intelligent swarm robotics. Although artificial evolution has proven to be a promising approach to coordinate the controller of an autonomous robot, its effectiveness in developing beneficial collective behavior in a multi-robot system has not been verified. Serveral computer simulations are conducted to examine how artificial evolution contributes to autonomous task allocation in a multi-robot system.