러시아인의 한국인식 : 19세기말~20세기초

강인구 서울시립대학교 서울학연구소 2001 서울학연구 Vol.- No.16

Before diplomatic relations existed Korea and Russia, Korea was already known to Russians. Despite the fact that Korean society isolated itself from the outside world from the 19th to the early 20th century, Russians received information about it in various ways. In the late 19th century Russian merchants, adventurers, scholars, diplomats, and military staff members frequently visited there. Even though Korea was a closed society, but Russians were continuously interested in its history, political situation, economic conditions, lifestyle, traditions, religions, the other aspects of Korean cultures, and their interest in Korean society gradually. After the country opened to the western world, the foreign relation of Korea were influenced by the interests and the foreign policy of the Imperial Powers. At this time Korea, China and Japan worried about further Russian expansion into northeastern Asia. This reflected the hostile thinking toward Russia held by other nations concerned with interest in this region, including England, China, Japan, and America. However there was a reason for this concern. In fact, since the middle 19th century when the borders in the Far East were settled, albeit roughly, the Russian government treated the matters of Manchuria and Korea Peninsula as one of its most important concerns, because they were connected with the problems of territorial integrity and economic development in this area. However this expansionist strategy of Russia proceeded unsuccessful, because the Powers, too, had a similar object, and, besides, the power of Russia was weak compared to the other Powers. Russians thought pre-modern Korea society to be under the control of China, after the Sino-Japanese war, the Russians thought that Korea was under the control of Japan, and that their theories about Chinese control were no longer applicable. In northeastern Asia, Russia aimed at getting an ice-free port, and this was very important from a national point of view. It was the contemporary problem of the Russians government to prevent Korea from being taken by the other Powers and, simultaneously, to have a more secure political, military, and economic influence in the region. Therefore it wanted to maintain the situation of 'an independent Korea'. Because the construction of the Siberian Railroad had not yet been finished and the other Powers were also concerned with the Korean Peninsula, it could enlarge its influence in it gradually. In the early twentieth century, the Russian government quickly changed its strategy for eastern expansion to a military line, even though this ran against the interests of Japan in the region. The Russian who visited Korea had pity and sympathy for the poverty they saw in towns and the poor life they witnessed in villages. They also paid attention to Korean diligence. The leaders of the Korean reformation movement believed that the Japanese would help Korea to reform itself and then become a strong power, but, as a matter of fact, Japanese had also prepared for aggression against Korea. Russians considered the actions of the Japanese toward Korea to represent a strategy of colonization. They had accurately estimated the intentions of the Japanese. In spite of being under influence of Chinese culture, for a long period of time there were many national characteristics peculiar to Koreans. Russians appreciated these national qualities. They judged that they were bright, active, and sensitive, and that they had a passion for education. They recognized that Confucianism was very important to Koreans. They considered the anti-Japanese spirit and the movement for an independent nation of Korea to be important stimuli in the awakening of Korean national character. In particular, they regarded the Dong-Hak movement and the Society of Independence as consequential factors inspiring Korean national sef-consciousness. In the twenty first century, Korean society is confronted with the problem of again opening the door in the new conditions of global society. Western-oriented intellectuals assert that these days are the time of globalization, so Korean need to open the whole Korean market to trade and reform under the IMF's direction. To maintain other opinions is very difficult. And there are no Russians to warn against the aggressive policy of Japan, for Russia has also opened itself to the outside world and has painfully withstood all hardships. If there is an aspect of the Korean character, which the Russians appreciated 100 years ago, it is that Korea must settle the problem of opening on the strategic level of the development of Korean society. In Korean society the problem of opening is a historical dilemma.

Protective Effects of Carnosine and Anserine on Oxidative Modification of Neurofilament-L Induced by Catechol Neurotoxin, Tetrahydropapaveroline

Inn Goo Kyeong,강정훈 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.2

Protective Effects of Carnosine and Anserine on Oxidative Modification of Neurofilament-L Induced by Catechol Neurotoxin, Tetrahydropapaveroline

Kyeong, Inn-Goo,Kang, Jung-Hoon Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.2

1948년 평양 소련문화원의 설립과 소련의 조소문화교류 활동

강인구(Kang Inn-Goo) 한국사연구회 1995 한국사연구 Vol.90 No.-

Nortriptyline 적정 용법을 위한 Population Pharmacokinetics 및 Bayesian Feedback법의 적용

신상구,김재진,장인진,홍진표,이경훈,우종인,박찬웅 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.5

The prediction performance of population kinetics and Bayesian feedback method was evaluated with respect to accuracy, bias, correlation in 18 normal subject and 29 patients treated with nortriptyline. The root mean squared error(RMSE) served as a precision. To obtain the population kinetic parameter of nortriptyline in native Korean, NONMEM approach which including structural and statistical kinetic model was used in analysing the 250 plasma level data from 18 normal subjects after single oral dose of 50mg. The results obtained from the approach using population kinetics-Bayesian feedback method indicate that the future nortriptyline plasma concentration could be predicted with relatively high accuracy(34.9ng/ml) and preccision(RMSE ; 25.6%) with a single measurement of plasma nortriptyline level after the nortriptyline dose. The accurary(23.3ng/ml) and precision(RMSE ; 15.5%) of the prediction were much more improved with two-point measurements of plasma nortriptyline level. In conclusion, feedback approach based on the population kinetic parameters seems to be accurate and reliable for predicting individual dosage requirements in patients treated with nortriptyline.

Oxidative modification of ferritin induced by hydrogen peroxide

( Jung Hwan Yoon ),( Sung Ho An ),( Inn Goo Kyeong ),( Myeong Seon Lee ),( Sang Chul Kwon ),( Jung Hoon Kang ) 생화학분자생물학회(구 한국생화학분자생물학회) 2011 BMB Reports Vol.44 No.3

Excess free iron generates oxidative stress that may contribute to the pathogenesis of various causes of neurodegenerative diseases. In this study, we assessed the modification of ferritin induced by H2O2. When ferritin was incubated with H2O2, the degradation of ferritin L-chain increased with the H2O2 concentration whereas ferritin H-chain was remained. Free radical scavengers, azide, thiourea, and N-acetyl-L-cysteine suppressed the H2O2-mediated ferritin modification. The iron specific chelator, deferoxamine, effectively prevented H2O2-mediated ferritin degradation in modified ferritin. The release of iron ions from ferritin was increased in H2O2 concentration-dependent manner. The present results suggest that free radicals may play a role in the modification and iron releasing of ferritin by H2O2. It is assumed that oxidative damage of ferritin by H2O2 may induce the increase of iron content in cells and subsequently lead to the deleterious condition. [BMB reports 2011; 44(3): 165-169]

노루궁뎅이 버섯균사체를 이용한 비타민나무 발효물이 생체고분자의 산화적 변형과 세포사멸에 미치는 보호 영향

김승섭(Seung-Sub Kim),경인구(Inn-Goo Kyeong),이미라(Mi-La Lee),김동구(Dong-Goo Kim),신지영(Ji-Young Shin),양진이(Jin-Yi Yang),이광호(Gwang-Ho Lee),음원식(Won-Sik Eum),강정훈(Jung-Hoon Kang) 한국식품영양과학회 2015 한국식품영양과학회지 Vol.44 No.1

본 연구에서는 노루궁뎅이 버섯균사체를 비타민나무 잎에 배양하여 조제한 노루궁뎅이 버섯균사체-비타민나무 발효물 열수 추출물이 생체고분자의 산화적 손상과 세포사멸을 보호할 수 있는지를 관찰하였다. 노루궁뎅이 버섯균사체-비타민나무 발효물의 항산화 활성을 DPPH radical, ABTS radical, peroxyl radical 소거활성 측정을 통해 알아보았다. 그 결과 노루궁뎅이 버섯균사체-비타민나무 발효물을 처리한 DPPH radical 소거활성은 500 μg/mL 농도에서 65.06%, ABTS radical 소거활성은 50 μg/mL 농도에서 98.83%, peroxyl radical 소거활성은 100 μg/mL 농도에서 44.03%로 높은 항산화 활성을 나타내었다. 노루궁뎅이 버섯균사체-비타민나무 발효물은 DNA의 산화적 손상을 효과적으로 억제하였다. 노루궁뎅이 버섯균사체-비타민나무 발효물 역시 사람의 혈청단백질과 Cu,Zn-SOD의 산화적 손상을 억제하였다. 세포에 H₂O₂를 처리하였을 때 세포생존율에 비하여 발효물을 100 μg/mL 농도로 전 처리한 세포생존율은 21.59% 높게 증가되었다. 또한 발효물을 50 μg/mL 농도로 처리했을 경우 세포 내 ROS의 축적이 유의적으로 감소되었다. 따라서 노루궁뎅이 버섯균사체-비타민나무 발효물은 항산화 활성뿐만 아니라 산화적 스트레스에 의해 야기되는 세포 독성에 대한 보호 작용이 뛰어난 것으로 사료된다. In this study, hot water extract from sea buckthorn (Hippophae rhamnoides L.) leaves fermented with Hericium erinaceum mycelium (SBT-HE) was assessed for protection against oxidative modification of biological macromolecules and cell death. Antioxidant activity of SBT-HE was evaluated based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, 2,2"-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical, and peroxyl radical scavenging assays. SBT-HE showed 65.06% DPPH radical scavenging activity at 500 μg/mL, 98.83% ABTS radical scavenging activity at 50 μg/mL, and 44.03% peroxyl radical scavenging activity at 100 μg/mL. SBT-HE significantly inhibited DNA strand breakage induced by peroxyl radical. SBT-HE also prevented peroxyl radical-mediated human serum albumin modification. SBT-HE effectively inhibited H2O2-induced cell death and significantly increased cell survival by 21.59% at 100 μg/mL. SBT-HE also reduced intracellular reactive oxygen species levels in H₂O₂-treated cells. The results suggest that SBT-HE can contribute to antioxidant activity and protect cells from oxidative stress-induced cell injury.

인진쑥 노루궁뎅이 버섯균사체 발효물의 항산화 활성

김승섭(Seung-Sub Kim),경인구(Inn-Goo Kyeong),이미라(Mi-La Lee),김동구(Dong-Goo Kim),신지영(Ji-Young Shin),양진이(Jin-Yi Yang),이광호(Gwang-Ho Lee),음원식(Won-Sik Eum),강정훈(Jung-Hoon Kang) 한국유화학회 2014 한국응용과학기술학회지 Vol.31 No.4

The hot water extract from Artemisia capillaris fermented with Hericium erinaceum mycelium (AC-HE) were assessed for the protection against oxidative modification of biological macromolecules and cell death. Antioxidant activity of AC-HE evaluated using 2,2-diphenyl-1-picrylhydrazyl radical, 2,2 -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical and peroxyl radical scavenging assays. AC-HE showed 61.73% DPPH radical scavenging activity at 500μg/mL, 97.39% ABTS radical scavenging activity at 250 μg/mL, and 44.18% peroxyl radical scavenging activity at 100 μg/mL. AC-HE were shown to significantly inhibited DNA strand breakage induced by peroxyl radical. AC-HE also prevented peroxyl radical-mediated human serum albumin modification. AC-HE effectively inhibited H2O2 induced cell death and significantly increased of the 11.47% cell survival at 100 μg/mL. AC-HE also decreased intracellular reactive oxygen species (ROS) levels in H2O2-treated cells. The results suggested that AC-HE can contribute to antioxidant and protected cells from oxidative stress-induced cell injury. 노루궁뎅이 버섯균사체(Hericium erinaceum)를 인진쑥(Artemisia capillaris)에 배양하여 조제한 AC-HE 열수 추출물이 생체고분자의 산화적 손상과 세포사멸을 보호할 수 있는 지를 관찰하였다. AC-HE의 항산화 활성을 DPPH radical, ABTS radical, peroxyl radical 소거활성 측정을 통해 알아보았다. 그 결과 DPPH radical 소거활성은 500 μg/mL 농도에서 61.73%, ABTS radical 소거활성은 250μg/mL 농도에서 97.39%, peroxyl radical 소거활성은 100 μg/mL 농도에서 44.18%로 나타났다. AC-HE은 DNA의 산화적 손상을 효과적으로 억제하였다. 또한 생체고분자물질인 사람의 혈청단백질의 산화적 손상을 억제하였다. 세포에 H2O2를 처리하였을 때 세포생존율에 비하여 발효물을 100 μg/mL농도로 전 처리한 세포생존율은 11.47% 증가했으며, 발효물을 50 μg/mL 농도로 처리했을 경우 세포내 ROS의 축적이 유의적으로 감소되었다. 따라서 AC-HE은 항산화 활성뿐만 아니라 산화적 스트레스에 의해 야기되는 세포 독성에 대한 보호 작용이 뛰어난 것으로 사료되었다.

Fermented Ethiopia Mocha Sidamo G2 coffee bean with Monascus ruber Mycelium Exhibits Anti-obesity Property and Improves Lipid Metabolism

Hoon Kim,yung-Joo Suh,Jun-Soo Lee,Kwang-Won Yu,Inn-goo Kyeong,Hee-yeon Lee,Ji-Young Shin 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

단위수량 및 팽창재 사용량이 콘크리트의 굳지않은 특성 및 건조수축에 미치는 영향

박천진(Park, Chun Jin),손호정(Son, Ho Jung),홍석인(Hong Seok Inn),한민철(Han, Min Cheol),한천구(Han, Cheon Goo) 한국콘크리트학회 2010 한국콘크리트학회 학술대회 논문집 Vol.2010 No.11