HPLC를 이용한 지역 농산물의 비타민 B₆ 함량 분석

최소라 ( So-ra Choi ),송은주 ( Eun-ju Song ),송영은 ( Young-eun Song ),최민경 ( Min-kyung Choi ),한현아 ( Hyun-ah Han ),이인석 ( In-sok Lee ),신소희 ( So-hee Shin ),이기권 ( Ki-kwon Lee ),최용민 ( Young-min Choi ),김행란 ( Haeng-r 한국식품영양학회 2017 韓國食品營養學會誌 Vol.30 No.4

Contents of water soluble vitamin B6 in a total of 62 agricultural products cultivated in local areas in Korea were analyzed by high performance liquid chromatography with fluorescence detector (HPLC/FLD). To verify the method of vitamin B6 analysis, a quality control chart was formulated with in-house control using a mixture of broccoli and shiitake mushrooms. Among cereals, high content of vitamin B6 measured 234.3~260.3 μg/100 g in dried mung bean and soybean. Vitamin B6 content of non-glutinous and glutinous black rice measured 105.0 μg/100 g and 129.7 μg/100 g, respectively. In vegetables, high content of vitamin B6 were measured in passion fruit (104.3 μg/100 g), gat (55.7~84.3 μg/100 g), gomchwi (31.3~88.0 μg/100 g) and garlic (72.7~98.3 μg/100 g). Among fruits, gold kiwi 'Zespri' and green kiwi 'Hayward' revealed high vitamin B6 content of 116.3 μg/100 g and 78.7 μg/100 g, respectively. In persimmons, daebongsi had high vitamin B6 content (36.0~72.7 μg/100 g) than bansi and sweet persimmon. Vitamin B₆ content in dried jujube and persimmon increased more than 86.7 μg/100 g compared to fresh materials. Among specialty crops, green tea powder (64.7~251.0 μg/100 g) and sansuyu (172.3 μg/100 g) revealed high content. Of mushrooms, vitamin B6 content of Sparassis crispa (139.3 μg/100 g) was the highest. Vitamin B6 content information of agricultural products in local areas in Korea collected from this experiment will be used as valuable preliminary data for grasp national nutritional status.

3′‐Sialyllactose as an inhibitor of p65 phosphorylation ameliorates the progression of experimental rheumatoid arthritis

Kang, Li‐,Jung,Kwon, Eun‐,Soo,Lee, Kwang Min,Cho, Chanmi,Lee, Jae‐,In,Ryu, Young Bae,Youm, Tae Hyun,Jeon, Jimin,Cho, Mi Ra,Jeong, Seon‐,Yong,Lee, Sang‐,Rae,Kim, Wook,Yang John Wiley and Sons Inc. 2018 British journal of pharmacology Vol.175 No.23

<P><B>Background and Purpose</B></P><P>3′‐Sialyllactose (3′‐SL) is a safe compound that is present in high levels in human milk. Although it has anti‐inflammatory properties and supports immune homeostasis, its effect on collagen‐induced arthritis (CIA) is unknown. In this study, we investigated the prophylactic and therapeutic effect of 3′‐SL on the progression of rheumatoid arthritis (RA) in <I>in vitro</I> and <I>in vivo</I> models.</P><P><B>Experimental Approach</B></P><P>The anti‐arthritic effect of 3′‐SL was analysed with fibroblast‐like synoviocytes <I>in vitro</I> and an <I>in vivo</I> mouse model of CIA. RT‐PCR, Western blotting and ELISA were performed to evaluate its effects <I>in vitro</I>. Histological analysis of ankle and knee joints of mice with CIA was performed using immunohistochemistry, as well as safranin‐O and haematoxylin staining.</P><P><B>Key Results</B></P><P>3′‐SL markedly alleviated the severity of CIA in the mice by reducing paw swelling, clinical scores, incidence rate, serum levels of inflammatory cytokines and autoantibody production. Moreover, 3′‐SL reduced synovitis and pannus formation and suppressed cartilage destruction by blocking secretion of chemokines, pro‐inflammatory cytokines, https://en.wikipedia.org/wiki/Matrix_metalloproteinases and osteoclastogenesis <I>via</I> NF‐κB signalling. Notably, phosphorylation of p65, which is a key protein in the NF‐κB signalling pathway, was totally blocked by 3′‐SL in the RA models.</P><P><B>Conclusions and Implications</B></P><P>3′‐SL ameliorated pathogenesis of CIA by suppressing catabolic factor expression, proliferation of inflammatory immune cells and osteoclastogenesis. These effects were mediated <I>via</I> blockade of the NF‐κB signalling pathway. Therefore, 3′‐SL exerted prophylactic and therapeutic effects and could be a novel therapeutic agent for the treatment of RA.</P>

만성두통 환자에서 한방 치료 후 인영혈 부위의 뇌혈류에 대한 연구

이충식 ( Chung Sik Lee ),박보라 ( Bo Ra Park ),박인숙 ( In Suk Park ),김지훤 ( Ji Hwon Kim ),이상언 ( Sang Eon Lee ),임진영 ( Jin Young Lim ),류영수 ( Yeoung Su Lyu ),강형원 ( Hyung Won Kang ),김태헌 ( Tae Heon Kim ) 대한한방신경정신과학회 2009 동의신경정신과학회지 Vol.20 No.1

Objectives: This study was performed to change of blood flow in In-Young(ST9) after treatment on chronic daily headache patients. Methods: Monitoring of TCD was examined in 10`s chronic daily headache patients before and after treatment. Mean velocity flow, systolic velocity and pulsatility index were analyzed from TCD at In-Young(ST9). The patients was laid for 20 minutes before treatment and also for treatment. Results: The results showed a significant(p<0.05: Paired T-test) decrease in mean velocity flow and systolic velocity. but there were no significant differences in pulsatility index. Conclusions: These results suggest that there were significant change on blood flow in In-young of chronic daily headache patients.

담도결석환자의 총수담관내 담즙에서 세균성장과 β-glucuronidase 활성도

이동기,홍사준,배선우,권상옥,장인호,김미라,강명서,이경원 연세대학교 원주의과대학 1992 원주의대논문집 Vol.5 No.1

InGaAs-based Tunneling Field-effect Transistor with Stacked Dual-metal Gate with PNPN Structure for High Performance

Ra Hee Kwon,Sang Hyuk Lee,Young Jun Yoon,Jae Hwa Seo,Young In Jang,Min Su Cho,Bo Gyeong Kim,Jung-Hee Lee,In Man Kang 대한전자공학회 2017 Journal of semiconductor technology and science Vol.17 No.2

We have proposed an InGaAs-based gateall-around (GAA) tunneling field-effect transistor (TFET) with a stacked dual-metal gate (DMG). The electrical performances of the proposed TFET are evaluated through technology computer-aided design (TCAD) simulations. The simulation results show that the proposed TFET demonstrates improved DC performances including high on-state current (Ion) and steep subthreshold swing (S), in comparison with a single-metal gate (SMG) TFET with higher gate metal workfunction, as it has a thinner sourcechannel tunneling barrier width by low workfunction of source-side channel gate. The effects of the gate workfunction on Ion, the off-state current (Ioff), and S in the DMG-TFETs are examined. The DMG-TFETs with PNPN structure demonstrate outstanding DC performances and RF characteristics with a higher n-type doping concentration in the In0.8Ga0.2As source-side channel region.

의사등방성 CFRP 적층판의 충격손상과 잔류강도에 미치는 고온환경의 영향

나승우,양인영 朝鮮大學校 機械技術硏究所 1998 機械技術硏究 Vol.1 No.1

본 연구에서는 고온하에서 의사등방성 CF/EPOXY 적층판이 이물충격손상을 받을때 충격에너지의 크기와 잔류굽힘강도와의 관계 및 충격에너지의 크기와 잔류강성계수와의 저하관계를 고찰하여 온도의 변화가 CFRP 적층재의 충격손상에 어떤 영향을 미치는가를 실험적 관계에서 고찰하였다. 상온에서는 충격손상에 의한 잔류강도 저하현상은 거의 없으나 시험편의 표면온도가 상승함에 따라 잔류강도는 저하하였다. 고온하에서 충격손상에 의한 굽힘강도 잔류계수 역시 충격면이 인장을 받은 경우가 충격면이 압축을 받는 경우 보다 작았으며, 굽힘강성 잔류계수는 온도변화 및 충격손상에는 상관없이 거의 일정하였다. This study deals with the effects of impact damages of CFRP laminates with respect to temperature changes through an observation of the interrelations between the impact energy vs. residual rigid modulus when the quasi-isotropic CFRP laminates are subjected to FOD (Foreign Object Damage) In the room temperature, the decreasing of the residual strength didn't generate by the impact damages. Also, with raising the specimen temperatures, the residual strength decreased for both the unimpacted specimen and the specimen subjected to impact damages. In the specimen of quasi-isotropic CF/FPOXY(〔0° 2/90°2/45° 2/-45°2〕sym), the decreasing for impact damage and the temperature change didn't occur in the case of the tension side of the impact surface than in compression side, In the case of impact surface under the tension, it was found that a buckling of local delamination was generated at the time the delamination section (F interfaces) was subjected to the compression. The CF/EPOXY specimen of quasi-isotropic laminates shows that the retention factors of bending strength is lower in the tension side of the impact surface than in the compression side. Bending stiffness retention factor remains almost constant irelevant to the temperature changes and the magnitude of impact damages.

국내 석회석들의 소성 탈황 동시반응 특성

신지훈 ( Ji Hoon Shin ),김예라 ( Yea Ra Kim ),국진우 ( Jin Woo Kook ),곽인섭 ( In Seop Kwak ),박경일 ( Kyoung Il Park ),이종민 ( Jong Min Lee ),이시훈 ( See Hoon Lee ) 한국공업화학회 2015 공업화학 Vol.26 No.5

In order to analyze and compare the desulfurization characteristics of five different kinds of domestic limestons, a thermogravimetric analyzer (TGA) was used in this study. Calcium carbonate contents of the domestic limestone varied from 91 to 96 wt%. Experimental temperature and sulfur dioxide concentration of 850 ℃ and 2,750 ppm, respectively were selected to simulate commercial operation conditions. In this study, the calcination and desulfurization reaction of limestones were simultaneously occurred and investigated to simulate in-situ desulfurization reaction in commercial circulating fluidized bed combustors. In addition, desulfurization reactivities of limes having the average particle sizes of 37.5, 90.5, 159, 356 and 750 μm were investigated. Desulfurization reactivities via simultaneous calcination and desulfurization reactions were 5-20% lower than those of using general desulfurization reactions.

초등학교 6학년 아동의 흡연에 관한 연구

박미라,박인숙 충남대학교 간호과학연구소 2003 충남대 간호학술지 Vol.6 No.1

The purpose of this study was to make a comparative analysis of smoking knowledge, attitude and behavior among children in their six year in elementary school to serve as a basis for the development of successful smoking prevention education program. The subjects were 600 boy and girl students in the sixth grade randomly selected from five elementary schools in north Chungcheong province. Data were collected for six days from September 2 through 7, 2002. To assess subjects smoking knowledge and attitude, Choi Hye-yeoung (2000)'s modified version of WHO(1982)'s Guidelines for the content of tobacco smoking surveys of the general population was again altered by this researcher for use in this study. The collected data were analyzed with SAS program. The frequency, percentage, mean and standard deviation were calculated, and t-test Chi-square test, ANOVA, and Logistics regression procedures were employed. The brief findings of this study were as 1) Out of the 600 students investigated, 21.83 percent(131 students) had a smoking experience, and among these students, 1.83 percent(11) smoked at present. 2) The collective average in smoking knowledge was 13.04 out of 19 points. The smoking-experience group got a mean of 12.78, and the non-experienced group got a mean of 13.12. The latter group had a slightly better knowledge than the former, but the difference between the two was insignificant(p=0.416). 3) The collective average in smoking attitude was 34.45, out of 40 points. The non-experienced group got a mean of 35.41, and the experienced group got a mean of 30.77. The former group had a more desirable attitude than the latter, and the gap between the two groups was very significant(p=0.000). 4) The smoking knowledge was positively correlated to the smoking attitude(r=0.24, p=0.000). 5) As for connections between smoking knowledge and general characteristics, school grades(F =10.97, p=0.000), the sources of smoking information(F=3.00, p=0.000), father educational background(F=4.06, p=0.003) and gender(t =-2.31, p=0.21) made a significant difference to the smoking knowledge. 6) Concerning relations between smoking attitude and general characteristics, the smoking attitude was different according to gender (t = -4.53, po=0.000), school grades(F=7.96, p=0.000), smoking or non- smoking of siblings(F=5.86, p=0.000), presence or absence of smoking friends(F=3.07, p=0.003), family atmosphere(F=4.87, p=0.008), experience of going on errands to buy a pack of cigarettes(t = -2.50, p=0.012), father's smoking or nonsmoking(F=4.87, p=0.026), and parent marital status (F=2.40, p=0.049). 7) Regarding connections between smoking experience and general characteristics, their smoking experience was different according to gender(x2=21.38, p=0.000), presence or absence of smoking friends (x2=55.81, p=0.000), smoking or nonsmoking of siblings(x2 = 15.11, p=0.004), experience of going on errands to buy a pack of cigarette(x2=7.50, p=0.006), mother's smoking or nonsmoking(x2 = 13.34, p=0.009), female relative's smoking or nonsmoking(x2 = 11.39, p=0.022), and mother's job (x2=4.64, p=0.031). 8) The factors associated with the smoking experience were the number of smoking friends(Wald x2=29.62, p=0.000) and smoking attitude(Wald x2=42.54, p=0.000).

Clinical Research Article : The analgesic effect of the ultrasound-guided transverse abdominis plane block after Laparoscopic cholecystectomy

( Yoon Suk Ra ),( Chi Hyo Kim ),( Guie Yong Lee ),( Jong In Han ) 대한마취과학회 2010 Korean Journal of Anesthesiology Vol.58 No.4

Background: Several methods are performed to control the pain after a laparoscopic cholecystectomy. Recently, the transverse abdominis plane block has been proposed to compensate for the problems developed by preexisting methods. This study was designed to evaluate the effect of the ultrasound-guided transverse abdominis plane block (US-TAP block) and compare efficacy according to the concentration of local analgesics in patients undergoing laparoscopic cholecystectomy. Methods: Fifty-four patients undergoing laparoscopic cholecystectomy were randomized into three groups. The patients in Group Control did not receive the US-TAP block. The patients in Group B0.25 and Group B0.5 received the US-TAP block with 0.25% and 0.5% levobupivacaine 30 ml respectively. After the general anesthesia, a bilateral US-TAP block was performed using an in-plane technique with 15 ml levobupivacaine on each side. Intraoperative use of remifentanil and postoperative demand of rescue analgesics in PACU were recorded. The postoperative verbal numerical rating scale (VNRS) was evaluated at 20, 30, and 60 min, and 6, 12, and 24 hr. Postoperative complications, including pneumoperitoneum, bleeding, infection, and sleep disturbance, were also checked. Results: The intraoperative use of remifentanil, postoperative VNRS and the postoperative demand of rescue analgesics were lower in the groups receiving the US-TAP block (Group B0.25 and Group B0.5) than Group Control. There were no statistically or clinically significant differences between Group B0.25 and Group B0.5. No complications related to the US-TAP block were observed. Conclusions: The US-TAP block with 0.25% or 0.5% levobupivacaine 30 ml (15 ml on each side) significantly reduced postoperative pain in patients undergoing laparoscopic cholecystectomy. (Korean Anesthesiol 2010; 58: 362-368)

멀티미디어 서버를 위한 슬롯 어드레싱 및 재참조 시간 기반 버퍼링 시스템 설계에 관한 연구

양종운,나인호 군산대학교 정보통신기술연구소 2000 情報通信技術硏究論文集 Vol.4 No.-

This paper is present how to maximize the buffer utilization in fixed amounts of buffer space and disk bandwidth. And, how to use concurrent streams in the multimedia server system to increasing data block's reusing rates. First, buffer sharing scheme that allows multiples to share buffers. Our analysis and preliminary simulation results indicate that buffer sharing could lead to as much as 50% reduction in total buffer space requirements. Second, we use buffer replacements scheme to data sharing, which is data blocks of reading from disk and reuse the data blocks to increasing disk bandwidth. Also, reduce the waiting time when users are request the any video stream in the stored in the multimedia server systems to satisfying real-time constraints and using fixed resource(i.e., buffer space, disk bandwidth and network bandwidth) Finally, we propose the schemes for reduce I/O bandwidth and maximizing the buffer utilizations in multimedia server systems.