제주민요 <서우젯소리>의 분석적 연구

김인규 제주대학교 1992 논문집 Vol.34 No.1

In this study I have concentrated on the musical characteristics of Cheju Islaild with reference to Soˇuje-sori which is well known as a representative folksong of Cheju. Soˇuje-sori has spread throughout the whole island as a farming song, a fishing song, and a entertainment song. The melody of this song can also be found in the shaman rituals. Folksong and shanman music are regarded as preserving the basic musical characteristics of a society. Therefore the musical stucture of Soˇuje-sori may be considered as representative of Cheju folksongs, since it seems to contain all the elements of Cheju folk music. In my study I analysed the melodic structure, and also the rhythmic patterns and musical forms of Soˇuje-sori. I selected 9 Soˇuje-sori from Han'guk u˘Minsok u˘mak-Chejudo pyoˇn; The Folkmusic in Kora-Cheju Island's Section for this study. Seven songs are in C major and two songs are in F major, but I used solmization for ease of comparison. I find preferable because Korean vocal tones do not share the intonation of Western music. One melody of Soˇuje-sori consist of 4 rhythmic cycles(changdan) in a 12/8 pattern. Thrse 4 rhythmic cycles alternate between solo-verse and chorus sections(meginu˘n-sori and pannu˘n-sori) in paired cycles-the former two are solo, and the latter two are chorus. Therefore I divided one melody into four phrases according to the rhythmic cycle, and gave a special number to each phrase. For example, each phrase is subdivided into 4;as 〔195-Ⅰ-메(Me)-앞(Ap)〕. 3. To explain this, 「195」 means own number in Han'guk u˘Minsok i˘mak-Chejudo pyo˘n; The Folkmusic in Kore-Cheju Island's Section,「1」 means the order of the melody, 「메(Me)」 means the solo section, and 「앞 (AP)」 indicates the 1st and 2nd phrases as shown in 〔EXAMPLE 1〕. ◁그림 삽입 ▷ (원문을 참조하세요) I also used the Koreall mensural notation (choˇnganbo) to record the melody line with a solmization. This notation comprises a set of 12 squares (choˇngan); a square is one beat. So Notation 1. is the transcription of the 9 songs which were selected from Han'guk u˘Minsok i˘mak-Chejudo pyo˘n; The Folkmusic in Kore-Cheju Island's Section-. In 〔Notation 1〕 we find some similar musical phrases which have similar melodic patterns. These patterns can be divided into several types as shown in 〔Notation 2〕. However 〔Notation 3〕 shows various strurutural melodies, for example, the most simple structure employs just one tone 「sol」, but the rather complex one has the structure 「sol- la-do-la-sol-mi」. Through detailed analysis, I found 23 kindrs of structural melodies and also identified a common structure 「do-la-sol」. Those 「do-la-sol」 structures are found mainly in the 1st, 2nd 4rd melodies But as an exception, different types of melody structure, either 「sol」 or 「sol-la」, appears in the 3rd phrase of each melody. In conclusion, the musical form of the So˘uje-sori is 「A-A-B-A」, 「A」 means the common melody structure 「do-la-sol」 and 「B」 is the exception.

衛生昆蟲에 대한 無公害農藥(昆蟲發育沮害劑)의 殺蟲機作 및 應用技術開發硏究

金正和,李炯來,李仁煥,李容揆,崔鐘錫 충북대학교 농업과학기술연구소 1993 農業科學硏究 Vol.10 No.2

In recently, much pesticides were used for control of agricultural and medical insects. The result of using pesticides were social problem because of environmental pollutions with pesticides in urban and farm village. The environmental pollutions were very serious. This experiment was conducted to eluciated of reduce to environmental pollution bring about using pesticides (organophosphates, carbamates, pyrethroids, and insect growth regulators) for control of medical insects(house fly, Musca domestica L and mosquito, culex pipiens pallens copuillett) and carried out the method of pest control. And the result are summarized as follows. The Kyongbuk house fly strain treated with pyriproxyfen on third instar larvae were very high mortality and low emergence. When use it, at the same time, we can reduce degree of environ-mental pollution and house fly populations. Using of imidan was effective in Seoul and Chungnam house fly strains. In mosquito larvae, the efficacy of icon to chungbuk strain, propoxur to Chungnam and Chungbuk strain, imidan to Kyongbuk strain, fenthion to Chungnam strain were excellent. In result of spraying imidan and icon on adult mosquitoes, the efficacy of icon was excellent than imidan. In esterase electrophoresis, third instar larvae of Chungnam house fly strain fed on artificial diet mixed with pyriproxyfen LC50 were very high activity of -Est-αl in early stage(second day after third instar larvae fed on diet), and the activity of Est-αl was very strong in late stage(se-vents day after third instar larvae fed on diet). In Kyongbuk strain, -Est-αl and Est-αl were detected in early and late stage, and activities of and -Est-αl and Est-αl were detected almost equally in late stage. It was very characteristic in this experiment. Third instar larvae fed on diet mixed with pyriproxyfen LC95 were detected -Est-αl and Est-αl almost equally. It was believed moulting control in insects. In electrophoresis with head, thorax, abdomen of house fly adult, -Est-α2 -Est-αl, Est-αl, Est-α2, Est-α3 were detected in abdomen in susceptible strain and only -Est-αl, was net detected in thorax -Est-αl, was detected in head, thorax and abdomen of Chungbuk strain and -Est-αl was detected in head, -Est-α2 in thorax of same strain. Activities of chitinase in late instar larvae of house flies fed on artificial diet mixed with pyrip-roxyfen LC50 and LC95, in pyriproxyfen LC95, analysised low and high again with the lapse of time in Kyongbuk strain. This was believed that the activity of chitinase was became high just before emergence. The result of filter paper test with mosquitoes were very high index(265) of esterase activity in Chungnam strain among all mosquito strains. In this reason, we can suppose that used pyrip-roxyfen (IGR) in Chungnam area for control pest. In this reason, it was more reasonable made use of pyriproxyfen than other pesticide in Chungnam area.

<i>In vitro</i> and <i>in vivo</i> evaluation of a novel polymer-free everolimus-eluting stent by nitrogen-doped titanium dioxide film deposition

Park, Dae Sung,Bae, In-Ho,Jeong, Myung Ho,Lim, Kyung Seob,Sim, Doo Sun,Hong, Young Joon,Lee, So-Youn,Jang, Eun Jae,Shim, Jae-Won,Park, Jun-Kyu,Lim, Han Chul,Kim, Han Byul Elsevier 2018 Materials Science and Engineering C Vol.91 No.-

<P><B>Abstract</B></P> <P>Inflammation and thrombosis are linked to the use of polymer-based drug-eluting stents (DES). The aim of this study was to develop a polymer-free everolimus (EVL)-eluting stent using nitrogen-doped titanium dioxide (N-TiO<SUB>2</SUB>) and verify its efficacy by <I>in vitro</I> and <I>in vivo</I> assessment in a porcine coronary model. Various analytical approaches such as scanning electron microscopy and atomic force microscopy, electron spectroscopy, Fourier transform infrared spectrometry and contact angle measurement were employed for the characterization. As a part of biocompatibility assessment, platelet adhesion and smooth muscle cell (SMC) proliferation were examined. Bare metal stent (BMS), N-TiO<SUB>2</SUB> stent, everolimus-eluting N-TiO<SUB>2</SUB> (N-TiO<SUB>2</SUB>-EVL) stent, and commercialized EVL-eluting stent (EES) were randomly placed in forty coronary arteries in twenty pigs. After four weeks of implantation, the stents were subjected to histological and quantitative analysis. The N-TiO<SUB>2</SUB> film used in this study was well coated without any cracks or peeling. Surface hydrophilicity (88.8% of angle decrement) could be associated with the decrease in surface roughness post N-TiO<SUB>2</SUB> deposition (37.0%). The platelet adhesion on the N-TiO<SUB>2</SUB> surfaces was less than that on the BMS surface. The proliferation of SMC was suppressed in the N-TiO<SUB>2</SUB>-EVL group (30.2%) but not in the BMS group. In the animal study, the percent area restenosis was significantly decreased in the N-TiO<SUB>2</SUB>-EVL group compared to that in the BMS group. The results (BMS; 47.0 ± 11.00%, N-TiO<SUB>2</SUB>-EVL; 31.7 ± 10.50%, and EES; 29.1 ± 11.21%, <I>n</I> = 10, <I>p</I> < 0.05) were almost at par with those of the commercialized EVL-eluting stent. The introduction of N-TiO<SUB>2</SUB> deposition during fabrication of polymer-free DES may be an efficient accessorial process for preventing in-stent restenosis and thrombosis.</P> <P><B>Highlights</B></P> <P> <UL> <LI> N-TiO<SUB>2</SUB> surfaces can help to reduce the platelet adhesion. </LI> <LI> In porcine model, N-TiO<SUB>2</SUB> everolimus decreased in-stent restenosis and fibrin deposition. </LI> </UL> </P>

In-direct localized surface plasmon resonance (LSPR)-based nanosensors for highly sensitive and rapid detection of cortisol

Jeon, Jinwoo,Uthaman, Saji,Lee, Jiyoung,Hwang, Hyejin,Kim, Gibum,Yoo, Pil J.,Hammock, Bruce D.,Kim, Christine S.,Park, Yeon-Su,Park, In-Kyu Elsevier 2018 Sensors and actuators. B, Chemical Vol.266 No.-

<P><B>Abstract</B></P> <P>Over-secretion of cortisol from the adrenal cortex is closely related to acute and chronic stress; thus, rapid and sensitive detection of cortisol in serum is of critical importance for preventing the progression of stress-related diseases. The binding of a biological molecule to the surface of metallic nanoparticles changes the local refractive index and in turn induces a shift in the localized surface plasmon resonance (LSPR) wavelength. Utilizing this phenomenon, we designed a novel disposable LSPR-based cuvette-type sensor for detecting cortisol in serum. The developed cuvette-type nanosensor consists primarily of an assembly of plastic unit sensors coated with gold nanoparticles on a single layer wherein cortisol-conjugated bovine serum albumin (BSA) is immobilized. In this system, a redshift in LSPR wavelength is induced by the binding of cortisol antibody onto cortisol-conjugated BSA immobilized on a gold nanoparticle surface in the nanosensor. In a competitive assay, the nanosensor could rapidly detect cortisol in both a PBS solution and serum (within 20 min) at concentrations ranging from 1 to 10,000 ng/mL (2.759–3 × 10<SUP>3</SUP> nmol/L), which is comparable to conventional enzyme-linked immunosorbent assay (ELISA) which typically requires longer than 4 h and complex sample preparation. Thus, we demonstrated that the LSPR-based nanosensor system developed in this study can provide a useful toolkit for a rapid, highly sensitive and reliable detection of cortisol hormone in a commercially available manner.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel disposable LSPR-based cuvette-type sensor for detecting cortisol in serum. </LI> <LI> Rapid, convenient, and sensitive method for detecting cortisol hormone in serum. </LI> <LI> Detect cortisol in both PBS solution and serum within 20 min at concentrations ranging from 1 to 10,000 ng/mL. </LI> </UL> </P>

내경동맥 지배 영역의 급성 허혈성 뇌졸중 환자에서 초 선택적 국소적 Urokinase주입술

김인규,김명규,김재규,조기현,김세종 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

된장이 고지방 및 고콜레스테롤 식이를 급여한 흰쥐의 지질 대사에 미치는 영향

이인규,김종규 대한보건협회 2002 대한보건연구 Vol.28 No.3

OBJECTIVE: This study was performed to investigate the effects of dietary supplementation of Korean traditional soybean paste(doen-jang) on the changes of serum biochemical components and histopathological changes of organs in rats fed a high fat and/or a high cholesterol diet. DESIGN: This was a single open-group prospective clinical intervention. METHODS: A total of one-hundred and twenty eight 3-weeks old male Sprague-Dawley rats were divided into 16 groups by a randomized blocking method. The rats consumed one of the experimental diets, the control diet, a high fat diet(40% of the total calories), a high cholesterol diet(1% of the total weight), and a high fat and high cholesterol diet for 13 consecutive weeks. Each of these diet groups were divided into 4 groups one with no soybean paste added, one with just 0.5% soybean paste added, one with 1% soybean paste added, and one with 5% soybean paste added. These levels were taken from the data of the National Nutrition Survey of Korea from 1994 to 1998. From this data, we know that Koreans on an average eat less than 0.5% soybean paste per person, per day. A Korean traditional soybean paste was used for this study. All of the preparation methods for the soybean paste followed the recommendations of Korea Food Research Institute. After ripening 6 months it was incorporated into the diet. Blood specimens were obtained at the baseline and after 13 weeks of dietary intervention. At the end of the study the organs(liver, heart, and kidney) were excised, and pieces of the organs were taken for histopathological examinatoin. Fool intake, body weight, food efficiency ratio, relative organ weights, and fecal lipid levels were determined at the end of the experiment. RESULTS: The feeding of a high fat and/or a high cholesterol diet resulted in many deleterious effects including increased food intake, increased weight gain, increased organ weights, increased fecal lipid levels,increased serum triglyceride, total lipid, free-cholesterol, easter-cholesterol, total cholesterol, low-density lipoprotein(LDL) cholesterol level, and atherogenic index, and increased lipase, aspartate aminotransferase(AST), alanino aminotransferase(ALT), cholinesterase(ChEase), and lactate dehydrogenase(LDHase) activities, and decreased high-density lipoprotein(HDL) cholesterol level, and most significantly severe fatty changes, in the livers, compared with the control and soybean paste control groups. The feeding of 0.5% soybean paste reduced the adverse effects of the high fat and/or the high cholesterol diet on the food efficiency ratio, weight gain, relative organ weights, fecal lipid levels, and improved serum lipid component levels. Significant decreases(p<0.05) in triglyceride, total lipid, total cholesterol, and LDL-cholesterol were seen. A significant increase was found in the level of HDL-cholesterol(p<0.05). A decrease was observed in atherogenic index. Also it recovered the levels of lipase, AST, ALT, ChEase, and LDHase activities. No significant changes in levels of serum free-cholesterol and easter-cholesterol were observed. It was helpful to reduce the severs histopathological lesions of livers. Although changes in these findings were observed in all of the groups with soybean paste, the most profound inhibitory changes were evident at the 5% level of soybean paste in the results of histological study of livers. In each group, adding soybean paste reduced the adverse effects of a high fat and/or a high cholesterol diet in ratio to the amount of soybean paste added to the diet. CONCLUSIONS: Dietary supplementation of 0.5% soybean paste resulted in reductions in several risk factors for lipid metabolism in rats, fed a high fat and/or a high cholesterol diet especially improved serum lipid component levels and the histopathological lesions of the livers. The feeding of 1% and 5% soybean paste showed even more reduction of risk factors. These results suggest that Korean soybean paste has a protective effect on a high fat and/or a high cholesterol diet. Long-term, placebo-controlled clinical trials are needed to evaluate the effect of soybean paste on the lipid metabolism in the human population.

스티렌 폭로 근로자들의 기중 및 혈중 스티렌과 요중 만델산의 관계 분석

정호근,강성규,양정선,김기웅,이종성,조영숙,박인정 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.1

The concentration of styrene in air in blood and mandelic acid in urine were checked for the 60 workers with normal liver function, exposed to styrene. Styrene in air were sampled with personal air sampler at least 4 hours and analyzed by gas chromatography. Blood and spot urine were collected at the end of shift with a vacuum tube and a polythylene bottle and analyzed by gas chromatography and high performance liquid chromatography. Means of air and blood styrene and urine mandelic acid were 8.16 ppm(geometric mean), 0.199 mg/L, and 0.519 g/g creatinine, respectively. The concentration of styrene in air and mandelic acid in urine were high in the FRP factories and low in polymerization factory. Styrene in blood showed large difference by the working process. Styrene in air showed a good correlation with mandelic acid in urine(r=0.6369) and styrene in blood(r=0.6371). The mandelic acid in urine and styrene in blood corresponded to exposure of 50 ppm styrene were 0.890 g/g creatinine and 0.434 mg/L. However, hippuric acid in urine did not show any correlation with styrene in air. Urine mandelic acid excretion expected ratio showed a tendency to decrease according to obesity index and to increase with alcohol consumption.

하지 절단자 보행의 운동역학적 분석

임규찬,박윤서,배성제,정철수,신인식,김복영 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

This study was conducted to investigate the biomechanical characteristics of the gait pattern in an amputee for the purpose of improving the proper gait posture and designing the prosthetic. The subjects were six males amputees and one normal person. The ground reaction force was measured using AMTI force platform. The conclusions were as follows; 1. In case of amputee group, the ground reaction force was revealed in specific figure according to position in which they used the prosthetic, whereas in case of normal person the ground reaction force was revealed in the figure of two humps in regard of vertical axis. 2. In case of amputee group, the ground reaction force in time between fight foot contact and left foot contact was deviated from a figure of rectangle, whereas in case of normal person the ground reaction force was revealed in the figure of rectangle. 3. In case of amputee group, the ground reaction force referred to both feet angle point of view was revealed in irregular figure, whereas in case of normal person the ground reaction force was revealed about 47。

산업재해 환자의 삶의 질, 자살사고 및 우울증상

김수인,연규월,하은희,우행원,김영철 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : 최근 산업재해(이하 산재) 및 교통사고 발생이 증가하면서 사고 후유증으로 치료받는 환자들이 늘어나고 있다. 산재를 포함한 각종 사고들은 환자의 신체적 상태를 변화시킬 뿐 아니라 이로 인한 사회적, 직업적, 경제적 문제들을 초래하게 되고 환자의 삶 전체를 변화시킬수 있다. 본 연구에서는 산재가 환자들에게 미치는 정신적 영향을 알아보기 위해 산재 환자들과 대조군에서 삶의 질, 자살사고 및 우울증상을 비교하였다. 방 법 : 연구대상은 1999년 12월 21일부터 12월 30일 사이에 경상남도 울산 마산·창원지역의 입원한 산재환자 169명이었고 정상 대조군은 울산의 공업단지 내 일반근로자 166명이었다. 평가군과 대조군 모두 남성이었고, 19세에서 60세였다. 모든 대상에서 일반 인구학적 특성, 삶의 질, 자살사고, 우울 증상을 평가하였고, 산재 환자군의 경우 사고일시, 사고원인, 치료기간, 손상부위를 추가로 조사하였다. 주관적 삶의 질은 한국판 스미스클라인 비챰 삶의 질척도로 평가하였고, 자살사고는 Beck의 자살사고(思考)척도로 평가하였으며, 우울증상은 PRIME-MD를 개선한 Patient Problem Questionaire의 우울증 척도로 평가하였다. 결 과 : 산재환자군과 대조군간 일반 인구학적 요인에서 통계적으로 유의한 차이 없었다. 산재환자군이 대조군에 비해 유의하게 낮은 삶의 질 척도 점수를 나타냈고, 유의하게 높은 자살사고와 우울증상을 나타냈다(p<.05). 산재환자군에서 연령, 결혼상태, 치료기간과 삶의 질 점수는 관련이 있었다. 30대 이상의 연령에서 유의하게 낮았고 10∼20대 연령에서 유의하게 높았으며, 미혼이거나 이혼, 별거중인 경우 유의하게 삶의 질 점수가 낮았고, 치료기간이 길수록 낮았다. 치료기간과 자살사고가 관련있었으며, 치료기간이 길수록 자살사고가 많았다. 산재환자군에서 손상부위에 따라 삶의 질 점수, 자살사고 점수와 우울증상이 유의한 관련이 있었다. 삶의 질 점수는 요추부 손상군에서 높았고, 경추부 손상군과 다발성 좌상환자군에서 낮았다(p<0.01). 자살사고 점수는 경추부손상군과 다발성 좌상 환자군에서 높았고, 요추부 손상군에서 낮았다(p<0.01). 연구 대상군에서 삶의 질 점수, 자살사고 점수, 우울증상간 유의한 상관관계가 있었다. 결 론 : 본 연구 결과 산재환자들은 일반 근로자들과 비교하였을 때 삶의 질이 낮다고 느끼고 있었으며, 주관적으로 우울감과 자살사고를 많이 나타냈다. 따라서 산재로 인한 우울 및 자살등의 증상을 예방하기 위해서는 조기 정신과적 치료 중재가 반드시 필요하다고 생각된다. Objective : As the occupational and traffic accidents are increased, patients who are treated for complications of accidents have been increased in recent years. Accidents including industrial injury affect the physical state of the patients and make social, vocational, and economic problems, so that they can affect the whole life of the patients. We performed this study to compare subjective evaluation of quality of life, depressive symptoms, and suicide ideation in both industrial injury patients and control subjects in order to know how industrial injury affect patients in psychiatric aspect. Method : The subjects were 169 inpatients who met the inclusion criteria of industrial injury patients and 166 healthy control subjects. All subjects were male and their age is from 19 to 60 years old. Demographic variables, quality of life, depressive symptom, suicide ideation were assessed in subjects. The types of injury and duration of treatment were assessed in patients. The quality of life was measured using the Korean version of SmithKline Beecham 'Quality of Life' Scale(KvSBQOL), and the suicide ideation was measured using the Scale for Suicide Ideation(SSI), and the depressive symptom was measured using the Dpression scale of Patient Problem Questionaire(PPQ) which were devised from Primary Care Evaluation of Mental Disorder(PRIME-MD). Results : 1) There were no significant differences in the general demographic variables between industrial injury patients and control subjects. 2)Scores of KvSBQOL were significantly lower, and SSI and Depression scale of PPQ were significantly higher in the industrial injury patients than control subjects(p<0.05). 3) In industrial injury patients, there was a correlation between the age and the scores of KvSBQOL(p<0.01). The scores of KvSQOL were lowest in older than 30's, highest in 10's-20's. No significant correlation was recognized between the age and the suicide ideation, the depressive symptoms. Threre was a correlation between the marital status and the scores of KvSBQOL(p<0.01). In unmarried, divorced or separated state, the scores of KvSBQOL were significantly lower than married state. There was a correlation between the the duration of treatment and the scores of KvSBQOL, the suicide ideation. As the duration of treatment was longer, the scores of KvSBQOL were significantly lower(p<0.01), and the scores of SSI were significantly higher(p<0.01). 4) In industrial injury patients, there was a significant correlation between the type of injury nd the scores of KvSBQOL, the suicide ideation, and the depressive symptoms. The scores of KvSBQOL were highest in the L-spine injury patients, lowest in the C-spine injury and multiple contusion patients(p<0.01). The scores of SSI were higher in the C-spine injury and multiple contusion patients, lowest in the L-spine injury patients(p<0.01). 5) In subjects, there was significant correlation between the scores of KvSBQOL, the scores of SSI, and the Depression scale of PPQ. Conclusion : Industrial injury patients feel bad about the quality of life and have more depression and suicide ideation. As a results, psychiatric intervention is needed for prevention of depression and suicide due to industrial injury.

의료방사선관리의 국제화 연구 : 핵의학분야의 의료방사선관리

김인규,오헌진,김혁주,오현주,박기정,이광용,이병영,정승환,강영규,이현구,김귀야,한상용,김연교,양현규,이명철 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

의료방사선은 인간의 질병진료와 예밤에 활용되어 각종 질병으로부터의 적절한 진단 및 의학발전에 중대한 역할을 담당하고 띤다. 또한 인공방사선원중 가장 큰 비중을 차지하고 있으며, 방사선원을 이웅한 이득과 손실을 생각쌀 때 피폭선량의 최소화 및 곡률적영향의 최소화를 위해 이득을 최대화하는 노력을 하고 있다. 진단뿐만 아니라 치료에도 사응하고 있는 인공방사선원의 적절한 관리를 위한 조사 및 연구는 국내에서는 아픽까진 실시되지 않았으며, 국외에서는 이미 활발한 조사 덴 연구가 이루어 지 고 있다. 일반적으로 의료기관의 핵의학분야에서 환자의 진단 및 치료에 사용되는 방사성의약품으로는 Tc-99in, Ga-67, 1-131, 71-201 등이 있으며 이를 이용한 방사능측정웅장비 및 치료뭉장비에는 Gamma Camera, 감마선재측기, 베타선계측기, Dose CaTibrator, PET(양전자방출전산화단층촬영장치)등이 있다. 이어 식푿의약품안전청f"서는 핵의학분야의 방사선보건학적 연구를 위해 핵의학분야의 진료와 관련된 인력, 시설, 장비, 방사성의약품의 사응, 핵의학적 진료형태 및 핵의학적 진료장치에 대한 성능관리등에 대해 조사·연구하였다. A nationwide survey was conducted in the Korea in 2001 to determine the facilities available and the level of activity at centres where radionuclide and therapy was practised in 2000. A response rate of 75% indicated that 120 centres were providing radionuclide therapy and diagnosis. About the good treatment of radionuclide using in medical, researched so many country, but not yet in. Generally nuclear medical part use Tc-99m, Ga-67, I-131, Tl-201 in diagnosis and therapy, radiation detector and equipment for therapy use Gamma Camera, beta-counter, Dose Calibrator PET(Positron Emission Tomography). 81% rate of centre has Gamma Camera and 97% rate of use Tc-99m, I-131 radionuclide. In-vitro did more than in-vivo test absolutely. So in KFDA researched in unclear medical part in Man-Power, facilities, equipment use of nuclear medicine, part of diagnosis and diagnosis equipment.