家兎에서 局所 血行遮斷 및 神經切斷이 筋肉變化에 미치는 影響에 關한 實驗的 硏究

蔡仁貞,李弘鍵 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.1

The pathogenesis of the ischemic myositis is still controversial although most agree that arterial obstruction or it’s reflex spasm is the main cause in the development of the ischemic contracture of the muscle. Concomitant venous occlusion and neural interruption must play an important role in the development of the ischemic myositis. In the meanwhile, failure in the early diagnosis and treatment of degeneration, be it due to occlusion of a major peripheral vesseles or to a compartmental compression and to interruption of a major nerves of a limb, may lead to a serious and irreversible change of the muscle. The purpose of this study is to evaluate and compare the degenerative or necrotic changes in skeletal muscles employing HBFP (hematoxylin basic fuchsin picric acid) stain following muscle ischemia or neural interruption and their restorations, either qualitatively and quantitatively. The author has undertaken an experimental study upon morphological changes of the muscle after ligation of vessels and cutting of nerve of the rabbit limb, and attempted to detect sequential changes in the affected muscle by histochemical staining method developed originally by Lie et al., that is, hematoxylin basic fuchsin picric acid (HBFP) staining method. One hundred and two rabbits weighing 2,000~2,500gm were divided into the three groups. In the group 1 which has 51 rabbits, the degenerative or necrotic changes were studied after the ligations of a) both femoral artery and vein b) the femoral artery and c) the femoral vein. Muscle biopsy was carried out of the tibialis anterior muscle after 5, 10 and 30 minutes, and 1,2,3,4,5,6,8,10,12,15,18,21,24 and 48 hours using one rabbit each time. In the group 2 which was 30 rabbits, the degenerative and necrotic or regenerative changes were studied after the release of the ligation of the femoral vessels a) when the degeneration were noted in the whole fibers and b) when the necrosis were noted in the half of whole fibers which are detected by the results of HBFP stain in the group 1. Muscle biopsy was carried out of the tibialis anterior muscle after 1,2,3,5,7 and 9 days using one rabbit each time. In the group 3 which was 21 rabbits, the degenerative of necrotic changes were studied after the cutting of the sciatic nerve. And then, muscle biopsy was carried out of the dame muscle with same intervals as for the group 1 and 2, that is from 5 minutes to 9 days, using one rabbit each time. The biopsied samples were fixed in formalin and stained with H & E and HBFP stain for microscopic evaluation of muscle changes. The results obtained are as follows: 1. After the ligations of the femoral vessels performed in the group 1, the earliest evidences of muscular degeneration were detected by HBFP staining method within 10 minutes. This is the case of the of the simultaneous ligation of the femoral artery and vein which is 32% of the total fibers. This is the case of the femoral artery ligation which is 28% of the whole. This is the case of ligation of the femoral vein which is 12% of the total. However, it was required more than 4 hours, 4 hours and 6 hours repectively to detect such changes by H&E staining method. 2. In the group 1, the degenerative or necrotic changes have progressed with time. In case of the simultaneous ligation of the femoral artery and vein the changes were most remarkable. In the case of the ligation of the femoral artery the changes were moderate. In the case of the ligation of the fenoral vein the changes were the smallest in a certain time. 3. In the group 1, the degenerative changes were detected by HBFP staining method in the whole fibers without evidences of the necrosis after 6 hours in the case of the simultaneous ligation of the femoral artery and vein; after 8 hours in the femoral artery ligation; after 18 hours in the femoral vein ligation. However, it was required 15 hours, 18 hours, and 48 hours respectively to detect such changes by H&E staining method without evidence of the necrosis. 4. In the group 1. the necrotic changes progressed in the half of the entire fibers in the case of the simultaneous ligation of the femoral artery and vein after 12 hours by HBFP staining method; in the case of the femoral artery ligation after 18 hours; in the case of the femoral vein ligation after 48 hours. 5. After the release of the femoral ligation after certain period of time given by the HBFP findings of the group 1, in the group 2, the necrotic changes became worse about 5% to 15% in the first or second days, and the changes were stabilized relatively up to the nineth day after its release by HBFP staining method. 6. After cutting the sciatic nerve in the group 3, the degenerative changes were detected within one hour by HBFP staining method, whereas it requires 9 days by H&E staining method to detect such changes. And as a whole, the degenerative changes progressed more slowly than in the group 1 and 2 in the course of time.

Temporal trends and in-hospital outcomes of primary percutaneous coronary intervention in nonagenarians with ST-segment elevation myocardial infarction

( Joon Young Kim ),( Myung Ho Jeong ),( Yong Woo Choi ),( Yong Keun Ahn ),( Shung Chull Chae ),( Seung Ho Hur ),( Taek Jong Hong ),( Young Jo Kim ),( In Whan Seong ),( In Ho Chae ),( Myeong Chan Cho ) 대한내과학회 2015 The Korean Journal of Internal Medicine Vol.30 No.6

Background/Aims: Data regarding the outcomes of primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in nonagenarians are very limited. The aim of the present study was to evaluate the temporal trends and in-hospital outcomes of primary PCI in nonagenarian STEMI patients. Methods: We retrospectively reviewed data from the Korea Acute Myocardial Infarction Registry (KAMIR) from November 2005 to January 2008, and from the Korea Working Group on Myocardial Infarction (KorMI) from February 2008 to May 2010. Results: During this period, the proportion of nonagenarians among STEMI patients more than doubled (0.59% in KAMIR vs. 1.35% in KorMI), and the rate of use of primary PCI also increased (from 62.5% in KAMIR to 81.0% in KorMI). We identified 84 eligible study patients for which the overall in-hospital mortality rate was 21.4% (25.0% in KAMIR vs. 20.3% in KorMI, p = 0.919). Multivariate analysis identified two independent predictors of in-hospital mortality, namely a final Thrombolysis in Myocardial Infarction (TIMI) flow < 3 (odds ratio [OR], 13.7; 95% confidence interval [CI], 3.2 to 59.0; p < 0.001) and cardiogenic shock during hospitalization (OR, 6.7; 95% CI, 1.5 to 30.3; p = 0.013). Conclusions: The number of nonagenarian STEMI patients who have undergone primary PCI has increased. Although a final TIMI flow < 3 and cardiogenic shock are independent predictors of in-hospital mortality, primary PCI can be performed with a high success rate and an acceptable in-hospital mortality rate.

Processing Effects of Feeds in Swine - Review -

Chae, B.J.,Han, In K. Asian Australasian Association of Animal Productio 1998 Animal Bioscience Vol.11 No.5

Processing is generally employed to alter the physical and chemical properties of feeds used in pig diets, using hammer/roller mills, pellet mills and extruders/expanders. The reported optimum particle sizes of corn are approximately $500{\mu}m$, $500-700{\mu}m$, $400-600{\mu}m$, for nursery, growing-finishing, and breeder pigs respectively. Optimum particle size of grains are affected by diet complexity. There was a trend towards reducing particle size in order to increase ADG in pigs fed a simple diet, though such was not the case for pigs fed a complex diet. Uniformity of particle size also affects the nutritional values of swine feeds. Uniform particle sizes would consistently give greater nutrient digestibilities. In terms of pellet quality, it is reported that a higher incidence of fmes in pelleted feeds has a direct correlation with poorer feed conversion ratio in pigs. Particle and pellet sizes are also very important for pelleting in terms of grinding, digestibility, stomach ulceration and pellet durability. A particle size of $600{\mu}m$, or slightly less, seemed optimal for com in fmishing pigs, and the 5/32 in. diameter pellets supported the best efficiencies of gain during nursery and finishing phases. Extruder and/or expander processes would allow the feed industry an increased flexibility to utilize a wider spectrum of feed ingredients, and improve pellet quality of finished feeds. It would appear that extruded or expanded diets containing highly digestible ingredients have little effect on the growth performance of pigs, and the feeding values of the feeds over pelleted diets were not improved as pigs grew. The extruder or expander is much more effective than a pelletizer in salmonella control. Gastric ulcerations and/or keratinizations were consistently reported in pigs fed mash and processed diets containing finely ground grains, whereas carcass quality was not affected by diet processing methods such as pelleting, extruding or expanding. In corn- or sorghum-based diets, the electrical energy consumption is 4-5 times higher in the expanding than in the pelleting process. But the expander's processing cost was half of that shown by an extruder. Finally, the decision of which feed processing technology to adopt would depend on the processing cost, and any potential improvement in growth performance and digestibilities of nutrients should offset the increased operating and capital costs related to the extruder/expander technology over mash or pelleting processes in pigs.

이산화질소 및 아황산 가스에 노출된 흰쥐에 대한 連翹敗毒散과 수종 한약물에 대한 실험적 연구

崔仁和,蔡炳允 慶熙大學校 1997 論文集 Vol.26 No.-

Sulfur dioxide and nitrogen dioxide are two major air pollutants. As it has been well known, the former plays indispensible role in London type smog incident and the latter is one of major components of photochemical oxidants. In the of industrial toxicology these two noxious gases are classified as irritant gas physiologically. And many reports on the acute and chronic intoxication by these two gases have been filed. Especially,a strong irritating nitrogen dioxide effect on the epithelium of air way tract are the formation or methemoglobin has been known as the main toxic action. Clinically pulmonary edema and congestion are beli-eved to main causes of death. Yongyopaedoksan(연요패독산) has been used in the oriental medical treatment of acute and chrom respiratory diseases, including laryngeal disorders and ocular irritant symptoms such as congestion burning, itching and scratch and so on. In order to investigate the clinical effect of Yongyopaedoksan(연요패독산), Maekmundong(麥門冬) Saengjihwang(生地黃) and Ilhwangyon(日黃連) on the rats exposured to 50ppm SO_2 & NO_2 for 5 hours an experimental study was done on hematologic changes, organ water contents and histopathologic pictures. The experimental groupe are the normal group, control group, S-1 group(oral medication Yongyopaedoksan), S-2 group(oral medication of Maekmundong), S-3 group(oral medication of Saengjihwang) and S-4 group(oral medication of Ilhwangyon). The results were summarized as follows; 1. On the hematologic change in the rats exposured to SO_2 in the Yongyopaedoksan group compared to the control, the increase in the value of hemoglobin & leucocytes was significant. In Maekmundong group, the number of leucocytes & eosinophil ratio were different significantly. In Saengjihwang group, the hematocrit values were increased significantly. 2. On the hematologic change in the rats exposured to NO_2 in the Yongyopaedoksan group compared to the control the hemoglobin hematocrit values and eosinophil ratio were decreased significantly. However the number of leucocytes was increased significantly. In the Maekmundong group, the reduction of hemoglobin & hematocrit values was significant. In the Saengjihwang group, the value of hemoglobin was reduced significantly. In the Ilhwangyon group, the decrease of the eosinophil ratio was significant. 3. On the change of water contents of left lung in the SO_2 exposure group, the Yongyopaedoksan Maekmundong & Saengjihwang group as compared to the control. the reduction was significant. 4. In the laryngeal histopathologic changes of SO_2 exposure group, all the sample groups were admitted of significant difference at congestion & inflammatory infiltrates as compared to the control. The edema of trachea in Saengjihwang & Ilhwangyon group as compared to the control were improved significantly. The congestion & inflammatory infiltrates of trachea ti four sample groups as compared to the control were improved significantly. 5. In the case of NO_2 exposure group, the edema and inflammatory infiltrates of larynx in Ilhwangyon on group as compared to the control were improved significantly. The edema of trachea in Saengjihwang & Ilhwangyon group as compared to the control was improved significantly. And the congestion & inflammatory infiltrates of trachea in all the sample groups as compared to the control were improved significantly.

대인관계 네트워크에서 연결정도와 노인의 신체적 건강 및정신적 건강과의 관련성 연구

채인화(Chae, In-Hwa),최승원(Choi, Sung-Won) 한국노년학회 2017 한국노년학 Vol.37 No.2

본 연구의 목적은 강화도 지역 노인의 신체적, 정신적 건강과 인간관계 크기를 설명해주는 사회연결망 연결 정도가 관련성이 있는지를 분석하여 노년기의 사회적 관계가 지역사회 노인의 건강을 예측할 수 있는지를 알아보고자 하는 것이다. 연구대상은 강화도 A군에 거주하는 65세 이상 남녀 노인 643명으로, 2011년에서 2012년 까지 실시된 “한국인의 사회적 삶, 건강과 노화에 대한 조사(KSHAP; Korean Social Life, Health and Aging Project)” 1년차 자료를 사용하여 위계적 회귀분석을 실시하였다. 분석결과 첫째, 통제변인으로 사용한 인구통 계학적 변인 중에서 성별, 소득, 연령은 노인의 신체적 건강과 상관관계를 보이는 것으로 나타났다. 남성이 여성보다, 소득이 높을수록, 연령이 낮을수록 신체적 건강이 더 좋은 것으로 나타났다. 둘째, 인구통계학적 변인 중에서 학력, 소득, 연령은 정신적 건강과 상관관계를 보이는 것으로 나타났다. 학력이 높을수록, 소득이 높을 수록, 연령이 낮을수록 정신적 건강이 더 좋은 것으로 나타났다. 셋째, 방향이 포함된 사회연결망에서 외향연 결정도와 내향연결정도 모두 노인의 신체적, 정신적 건강을 예측하는 것으로 나타났다. 본 연구결과는 한 개인의 대인관계가 노인의 건강을 예측하는 데 있어 내가 교류한다고 생각하는 사람의 수(외향연결정도) 뿐만 아니라 나와 교류한다고 생각하는 사람의 수(내향연결정도)도 같이 고려할 필요가 있다는 것을 시사하며, 방향에 따른 연결정도의 두 지표가 신체적, 정신적으로 취약할 수 있는 고립된 개인들을 찾아내는데 활용될 수 있다는 점에서 지역사회 노인에 대한 건강 증진 및 복지 차원에서 의미가 있다. The purpose of this study is to see if we can predict the health of seniors of community by analyzing the connection between social network degree and mental and physical health of old people who live in the areas of Gangwha Island. The subjects of the study were men and women aged 65 or over, a total of 643 that resided in Ganghwa A-county. The survey was conducted on Korean Social Life, Health and Aging Project from the year 2011 to 2012. Regression analysis was carried out using the data. The analysis results were as follows. First, it showed the relationships between income, gender, age out of demographic variables used as control variable and old persons’physical health. The research results showed that physical health was better in case of the higher incomes, men, and lower age. Second, out of demographic variables, educational background, income, age was shown to correlate with mental health. The research results showed that mental health was better in case of the higher incomes, higher educational background, and lower age. Third, in social network including direction, both out-degree and in-degree were shown to predict old people’s physical and mental health. The results of this study suggest that not only out-degree but also in-degree should be considered in predicting the health of elderly persons by a person s human relationship. Also, two indicators of degree are meaningful in the dimension of health promotion and welfare of the old in that they can be used for finding isolated individuals that can be physically and mentally vulnerable.

공단지역과 청정지역에서 재배되는 농작물과 토양중 중금속함량 비교

이인숙,김동현,조영채 忠南大學校 環境問題硏究所 1995 環境硏究 Vol.13 No.-

This study was performed to investigate the degree of pollution and the relationship of heavy metal contents in crops and soils collected from unpolluted area of Cheong yang-gun and industrial complex areas of Taejon-city, Cheong ju-city, Cheon an-city, On yang-city from 1, August to 30,September, 1994. 4 industrial complex areas were divided into the area within industrial complex, the area of 1Km and 2Km distant from the industrial area. The author collected 6 kinds of crops(perilla leaf, chinese cabbage, radish, sweet potato, guinea pepper, and egg plant) and their soils from each areas and measured 7 items of heavy metals (Cd, Pb, Cr, Ni, Zn, Mn, Cu) by I.C.P. (Inductively Coupled Plasma Emission Spectroscopy). pH was also measured in soil samples. 1. In the crop samples, the average contents of Pb, Cr, Ni, Mn, and Cu were significantly increased in the industrial complex areas as compared with those in the unpolluted area. In the perilla leaf(Pb, Cr, Ni, Mn, Cu), chinese cabbage(Cr,Ni,Cu), radish(Pb, Cr, Ni, Cu), sweet potato(Pb, Cr, Ni, Zn, Cu), guinea pepper(Pb, Cr, Ni, Mn) and egg plant(Pb, Cr, Cu) the content of heavy metals of industrial complex areas were significantly increased as compared with those in unpolluted areas, Cheong yang-gun. 2. In the soil samples, the average contents of Cd, Pb, Cr, and Cu were also significantly increased in the industrial complex areas as compared with those in the unpolluted area, and Mn was significantly increased in the unpolluted area as compared with those in the industrial complex areas. 3. In the crop and soil samples, the average contents of Cd, Pb, Mn, and Cu were significantly increased in the soils as compared with those of the crops. However, the concentration of Cr in the crops was higher than that in the soils. 4. The contents of heavy metals in crops and soil showed decreasing tendency acording to the distance from the industrial complex area. There was a significant positive correlation beteen the contents of Zn, Mn and Cr in crops and soils. 5. The pH did not show a large difference by geographical location, and it maintained between pH 5.0 and pH 8.0.

高血壓性 腦卒中(中風)에 對한 東西醫學的 疫學硏究

鄭在赫,具本泓,張仁圭,崔栖영,柳東俊 中央醫學社 1983 中央醫學 Vol.45 No.3

Epidemiological studies were done on the 162 hypertensive cerebrovascular accid-ents cases admitted in the affiliated Oriental Medicine School Hospital Kyung Hee University in 1983 and the following results were obtained. 1. The male to female ratio of the patients was 1. 3 : 1 and the age distribution frequency was as follows; fifties, forties, seventies and thirties(Table 2). 2. In the C.T.A., there were 119 cases of cerebral thrombosis(73.5%) and 45 cases of intracerebral hemorrhage (26.5%). The ratio was 2.8 : 1. In the former the male to female ratio was 1.3 : 1, in the latter it was 1.2 : 1(Table 3). 3. There were considerable numbers of recurrent cases as shown in Table 4. The first attack was noted in 125 cases(77.2%), the 2nd attack 30 cases(18.5%), the 3rd attack 6 cases(3.1%), 4th attack 1 case(0.6%). The male to female ratio was as follows. In the first attack it was 1. 3 : 1, in the 2nd attack 1.1 : 1, the 3rd attack 5.0: 1, the 4th attack was noted only in one male case. 4. The occupational frequency order was as follows(Table 5). Unemployed initi-ated with 45 cases(27.8%), home care 21 cases, Unspecified 19 cases, office worker, business men, farmers and public official etc. 5. The regional distribution was as follows(Table 6). Seoul city led with 102 cases (63. 0%) then it was followed by Kyung-Gi, Chung-Cheong, Kyung-Sang, Kang-Won and Jon-Ra province. 6. The systolic pressures at admission were disclosed as follows(Table 7). There were 42 cases(male 20 cases-12.3%, female 22 cases-13.6%) of systolic hypertens-ive over the WHO standard of 160mmHg, the mean value of systolic pressure was 145mmHg. The diastolic pressures at admission were shown as follows(Table 8). There were 92 cases(56.8 %) (male 48 cases-29.6%' female 44 cases-27.2%) of diastolic hypertension over the WHO standard of 95mmHg, the mean value of diastolic pressure was 98mmHg. 7. The patient's favors to salty food, animal fatty food, cigarettes and alcoholic beverage were examined (Table 9). Salty' foods were favored by 78 cases(48.2%), animal fatty foods by 78 cases(48.2%), cigarettes by 64 cases(39.5%) and alcohol imbibers were noted in 77 cases(47.5%) as shown in table 9. 8. The family history of C. V.A and hypertension was studied (Table 10). In C. V.A there were 28 cases (17.3%) with parental history, 12 cases (7.4%) with siblings history and 7 cases (4.3%) with other relatives, and in hypertension there appeared 14 cases(8.6%) with parental history, 9 cases(5.6%) with sibling history and 6 cases(3.7%) with other relatives. 9. In the past history, hypertension led with 124 case s(76.5°%), then C.V.A 37 cases(22.9%) and diabetes mellitus 33 cases(20.4%)(Table 11). 10) In treatment the frequently used herbal recipes were Gamichungshimtang(), BoSimgunbitang( ), Kyuntongdudamtang( ) in 15% of the cerebral hemorrhage cases, respectively; Camichungshimtang( ) in 20% Yangkyeuksan(), Chowishungchumtang(), Yukmichihwangt-ang() in 6%, respectively, in cerebral thrombosis. The most frequently used acupuncture points in C. V. A were shown in Table 12. Taechung(), Habgok ( ), Joksamri(), Oekwan(), Chungjue( ), Jokimueb.(), Kokji(), Taebak() were frequency order used in C.V.A of both cerebral thrombosis and hemorrhage. 11. In admitted C.V.A patient care, it was stressed that the Oriental Medical Hospital plays important roles and, accordingly, the propriety of East-West medical cooperation was addressed. 12. Through classified disease distribution of admitted patients in the Oriental Medicine Hospital the epidemiological epitome of cerebrovascular accidents and other diseases was presented. * East-West medicine denotes a methodology of approaching a creative medicine through cooperation between East-West medicines.

전기화상후 Prostaglandin F2a와 Thromboxane B2의 증가에 대한 Flurbiprofen, Prednisolone 및 Gabexate mesilate의 억제효과

조병채,김인규,변진석,백봉수 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

This study was conducted to clarify the inhibitory effect of flurbiprofen, prednisolone, and gabexate mesilate on the synthesis of prostaglandin F2a and thromboxane B2 in the tissue of electrical burn. one hundred sixty Sprague-Dawley rats, 250gm of body weight in average, were divided into 4 groups of control, flurbiprofen, prednisolone and gabexate mesilate administred group. Fourty rats of the each group were subdivided into 1st, 2nd, 4th, 7th postburn day with 10 rats in each subgroup. Ten rats were used for normal values of prostaglandin F2a and thromboxane B2. Flurbiprodfen 30mg/kg was given per mouth, and prednisolone acetate 5mg/kg and gabaxate mesilate 50mg/kg were administred intramuscularly 5 minutes after burn injury and then once a day. All but bone tissue of within 2cm area of the current entry were harvested and ground into homogenate. The levels of prostaglandin F2a and thromoboxane B2 were measured by Radioimmunoassay. The results were as followings: In normal rat tissue, the level of prostagland F2a and thromboxane B2 were 15.8±1.8 and 17.6±2.8ng/mg protein in each. In the control group the levels of both prostaglandin F2a and thromboxane B2 increased abruptly to 5 times and 7 thimes in the first day and maintained the same level in the second day. After then they rapidly decreased and returned to a near normal level in the fourth day. The increase of thromboxane B2 was more remarkable than that of prostaglandin F2a. In the flurbiprofen group, the level of thromboxane B2 was not inerease but kept at a normal level. The average level of prostaglandin F2a in the post-burn first and second day was 59.5% lower than of the control group. The average level on the post-burn first and second day was 61% lower in thromboxane B2 and 33% lower in prostaglandin F2a in the prednisolone group, and 68% lower in throboxane B2 and 48% lower in prostaglandin F2a in the gabexate mesilate group, compared to the control group. These findings suggest that electrically injured tissue is vigrously progressive due to rapid increase of thromboxane B2 and prostaglandin F2a, as inflammatory mediators, in the post-burn first and second day, is nonprogressive after the post-burn fourth day. The flurbiprodfen was the most effective of the three drugs(flurbiprofen, gabexate mesilate, prednisolone in order of effectiveness) to suppress the synthesis of thromboxane B2 prostaglandin F2a of the electrieally injured tissue.

高血壓性 腦卒中(中風)에 對한 東西醫學的 疫學硏究

鄭在赫,具本泓,張仁圭,崔栖瀅,柳洞俊 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 1983 東西醫學硏究所 論文集 Vol.2 No.1

Epidemiological studies were done on the 162 hypertensive cerebrovascular accidents cases admitted in the affiliated Oriental Medicine School Hospital Kyung Hee University in 1983 and the following results were obtained. 1. The male to female ratio of the patients was 1.3:1 and the age distribution frequency was as follows; fifties, forties, seventies and thirties(Table 2.) 2. In the C.V.A., there were 119 cases of cerebral thrombosis(73.5%) and 45 cases of intracerebral hemorrhage(26.5%). The ratio was 2.8:1. In the former the male to female ratio was 1.3:1, in the latter it was 1.2:1(Table 3). 3. There were considerable numbers of recurrent cases as shown in Table 4. The first attack was noted in 125 cases(77.2%), the 2nd attack 30 cases(18.5%), the 3rd attack 6 cases(3.1%) , 4th attack 1 case(0.6%). The male to female ratio was as follows. In the first attack it was 1.3:1, in the 2nd attack 1.1:1, the 3rd attack 5.0:1, the 4th attack was noted only in one male case. 4. The occupational frequency order was as follows(Table 5). Unemployed initiated with 45 cases(27.8%), home care 21 cases, Unspecified 19 cases, office worker, business men, farmers and public official etc. 5. The regional distribution was as follows(Table 6). Seoul city led with 102 cases (63.0%) then it was followed by Kyung-Gi, Chung-Cheong, Kyung-Sang, Kang-Won and Jon-Ra province. 6. The systolic pressures at admission were disclosed as follows(Table 7). There were 42 cases(male 20 cases-12.3%, female 22 cases-13.6%) of systolic hypertensive over the WHO standard of 160mmHg, the mean value of systolic pressure was 145mmHg. The diastolic pressures at admission were shown as follows(Table 8). There were 92 cases(56.8%)(male 48 cases-29.6%, female 44 cases-27.2%) of diastolic hypertension over the WHO standard of 95mmHg, the mean value of diastolic pressure was 98mmHg. 7. The patient's favors to salty food, animal fatty food, cigarettes and alcoholic beverage were examined(Table 9). Salty foods were favored by 78 cases(48.2%), animal fatty foods by 78 cases(48.2%), cigarettes by 64 cases(39.5%) and alcohol imbibers were noted in 77 cases(47.5) as shown in table 9. 8. The family history of C.V.A and hypertension was studied (Table 10). In C.V.A there were 28 cases(17.3%) with parental history, 12 cases(7.4%) with siblings history and 7 cases(4.3%) with other relatives, and in hypertension there appeared 14 cases(8.6%) with parental history, 9 cases(5.6%) with sibling history and 6 cases(3.7%) with other relatives. 9. In the past history, hypertension led with 124 cases(76.5%), then C.V.A 37 cases(22.9%) and diabetes mellitus 33 cases(20.4%)(Table 11). 10. In treatment the frequently used herbal recipes were Gamichungshimtang(加味淸心湯), Bosimgunbitang(補心健脾湯), Kyuntongdodamtang(腱痛導痰湯) in 15% of the cerebral hemorrhage cases, respectively, Gamichungshimtang(加味淸心湯) in 20%, Yangkyeuksan(凉膈散), Chowisungchongtang(調胃升淸湯), Yukmichihwangtang(六味地黃湯) in 6%, respectively, in cerebral thrombosis. The most frequently used acupuncture points in C.V.A were shown in Table 12. Taechung(太衡) , Habgok(合谷), Joksamri(足三里), Oekwan(外關), Chungjue(中渚), Jokimeub(足姙泣), Kokji(曲池), Taebak(太白) were frequency order used in C.V.A of both cerebral thrombosis and hemorrhage. 11. In admitted C.V.A patient care, it was stressed that the Oriental Medical Hospital plays important roles and, accordingly, the propriety of East-West medical cooperation was addressed. 12. Through classified disease distribution of admitted patients in the Oriental Medicine Hospital the epidemiological epitome of cerebrovascular accidents and other diseases was presented.

도시지역 일부 고등학생들의 우울과 불안에 관한 조사 연구

곽은주,송인순,정용준,조영채 韓國保健敎育.健康增進學會 2003 보건교육건강증진학회지 Vol.20 No.2

This study has examined the degree of depression and anxiety among high school students in an urban area and then explored the factors influencing their depression and/or anxiety status. Self-administered questionnaires were offered to 2,381 students from ten high schools in Daejon Metropolitan City. The items for investigation included such factors as various characteristics of school and family life, daily life style, and the degree of depression and anxiety. Based on the study results, the following conclusions were made; 1. The distribution according to the depression degree has shown that 61.9% of students were normal, 32.9% of students had mild depression, 5.0% moderate depression, and 0.3% severe depression. As for anxiety, 40.2% of students were normal, while 19.1% were classified as having anxiety and 40.7% borderline anxiety. 2. As regards to the degree of depression and anxiety, it was greater in girls than boys, in 3rd graders than 1st and 2nd graders, and in the groups who have recieved lower grades in studies, who had poor relations with their friends and a low feeling of satisfaction with school life. In particular, concerning various characteristics of family life, the scores of depression and anxiety were higher in the groups whose financial conditions were poor, whose parents' interests were lower, whose degree of satisfaction with their family and school life was lower, than their counterparts. 3. According to their life styles higher scores of depression and anxiety were found in the groups whose sleeping time was inappropriate, whose breakfasts were skipped, who ate daily snacks, who didn't take regular exercises, and who had poor health habits, compared to their counterparts, respectively. 4. As for the correlation between the degree of depression and its associated variables, the higher scores of depression were in positive correlation with the groups who had lower grades in studies, poor relation with their friends, low feeling of satisfaction with school and home life, low parents' interest, poor subjective condition of health, breakfast skipping, lack of regular exercises, and lower indices of health habits. 5. As for anxiety, the higher scores of anxiety were in the positive correlation with the groups with poor relation with their friends, low feeling of satisfaction with school and family life, poor subjective condition of health, lack of regular exercises, and poor health habits. 6. The influential factors on the depression of students were selected such as subjective condition of health, sex, feeling of satisfaction with family and school life, grades in studies, relation with their friends, presence of regular exercises, degree of interest of parents, sleeping time, cigarette smoking and eating breakfast. 7. The influential factors on the anxiety state of students were selected such as subjective condition of health, feeling of satisfaction with family and school life, sex, sleeping time, regular exercises, cigarette smoking, snacking and relations with their friends. The present study results suggest that girls rather than boys, higher graders than lower ones are more vulnerable to anxiety and depression state, and besides, various characteristics of school and family life, and daily life style can be influential on students' emotional states. Therefore, better management of psychological status of students is thought to require a wide variety of measures to modify the influencing factors and to encourage social support.